Centessa PharmaceuticalsCNTA
13F holders, Q4 2025 (December 31)147holders +22
40new positions
20sold out
6famous investors
$25.01avg. 13F price*
At the end of Q4 2025, 147 institutions reported holding Centessa Pharmaceuticals Ltd. (CNTA) in their 13F filings, up 22 from Q3 2025. 40 opened new positions and 20 sold out. The largest holders were Medicxi Ventures Management (Jersey) Ltd ($499.3M), Avoro Capital Advisors LLC ($364.0M) and Adage Capital Partners Gp, L.L.C. ($282.2M). 6 famous investors held it, including Lee Ainslie (0.4% of Maverick Capital's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Centessa Pharmaceuticals Ltd.
- CUSIP
- 152309100
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 40 | $260.7M |
| Exits | 20 | $91.2M |
All 13F filers, Q3 2025 → Q4 2025: 32,338,858 shares bought and 16,902,525 shares sold, net +15,436,333 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 147 holders
| Medicxi Ventures Management (Jersey) Ltd | 59.80% | No change | 19,963,157 | $499.3M |
| Avoro Capital Advisors LLC | 3.58% | Add +34.7% | 14,555,555 | $364.0M |
| Adage Capital Partners Gp, L.L.C. | 0.43% | Add +12.4% | 11,281,741 | $282.2M |
| Index Venture Life Associates VI Ltd | 100.00% | No change | 9,961,789 | $249.1M |
| FMR LLC | 0.01% | Add +42.8% | 8,961,939 | $224.1M |
| General Atlantic, L.P. | 5.33% | Reduce -36.8% | 6,117,715 | $153.0M |
| Farallon Capital Management, L.L.C. | 0.70% | Add +24.1% | 5,377,068 | $134.5M |
| TCG Crossover Management, LLC | 3.55% | Add +36.7% | 4,286,480 | $107.2M |
| Janus Henderson Group PLC | 0.05% | Reduce -24.3% | 4,093,608 | $102.4M |
| Siren, L.L.C. | 3.00% | Add +24.8% | 4,027,517 | $100.7M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -18.3% | 3,927,343 | $98.2M |
| EcoR1 Capital, LLC | 3.57% | Add +466.4% | 3,115,000 | $77.9M |
| Perceptive Advisors LLC | 1.34% | Reduce -5.9% | 2,917,634 | $73.0M |
| Franklin Resources Inc. | 0.01% | Reduce -7.4% | 2,368,381 | $59.2M |
| Federated Hermes, Inc. | 0.10% | Add +33.9% | 2,342,139 | $58.6M |
| First Light Asset Management, LLC | 4.36% | Reduce -37.3% | 2,278,940 | $57.0M |
| Braidwell LP | 2.10% | New | 2,188,320 | $54.7M |
| Deep Track Capital, LP | 1.14% | New | 2,000,000 | $50.0M |
| Millennium Management | 0.03% | Add +107.3% | 1,870,671 | $46.8M |
| RTW Investments, LP | 0.45% | Reduce -21.9% | 1,790,837 | $44.8M |
| Maverick Capital | 0.44% | New | 1,643,724 | $41.1M |
| Foresite Capital Management VI LLC | 10.31% | Add +3.8% | 1,364,019 | $34.1M |
| Cormorant Asset Management, LP | 1.88% | Reduce -31.2% | 1,325,000 | $33.1M |
| Capital World Investors | 0.00% | Add +69.2% | 1,158,699 | $29.0M |
| Stempoint Capital LP | 4.95% | Add +76.1% | 1,154,114 | $28.9M |
| American Century Companies Inc. | 0.01% | Add +3.0% | 1,129,758 | $28.3M |
| Morgan Stanley | 0.00% | Reduce -1.4% | 1,109,098 | $27.7M |
| Sofinnova Investments, Inc. | 1.19% | New | 1,104,274 | $27.6M |
| Commodore Capital LP | 1.66% | Reduce -64.9% | 1,000,000 | $25.0M |
| Bank of America Corp. | 0.00% | Add +71.7% | 949,544 | $23.7M |
| Jain Global LLC | 0.23% | Add +278.5% | 915,803 | $22.9M |
| D. E. Shaw & Co. | 0.02% | Add +1191.6% | 831,636 | $20.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +214.7% | 779,001 | $19.5M |
| Octagon Capital Advisors LP | 2.35% | Reduce -9.6% | 750,000 | $18.8M |
| Baker Bros. Advisors LP | 0.10% | New | 670,751 | $16.8M |
| Affinity Asset Advisors, LLC | 1.11% | Reduce -45.8% | 600,552 | $15.0M |
| BlackRock, Inc. | 0.00% | Add +45.1% | 592,604 | $14.8M |
| PFM Health Sciences, LP | 1.52% | Reduce -11.2% | 591,601 | $14.8M |
| 5AM Venture Management, LLC | 4.57% | Reduce -14.7% | 580,945 | $14.5M |
| Woodline Partners LP | 0.06% | Add +437.1% | 578,251 | $14.5M |
| UBS Group AG | 0.00% | Add +531.0% | 537,518 | $13.4M |
| Citadel Advisors | 0.01% | Add +279.0% | 519,962 | $13.0M |
| Armistice Capital, LLC | 0.31% | Add +32.3% | 500,000 | $12.5M |
| Jane Street Group, LLC | 0.01% | Add +1893.3% | 480,204 | $12.0M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -41.8% | 468,815 | $11.7M |
| Silverarc Capital Management, LLC | 1.66% | Add +224.4% | 458,203 | $11.5M |
| Walleye Capital LLC | 0.07% | New | 441,160 | $11.0M |
| Candriam S.C.A. | 0.05% | Add +15.3% | 395,623 | $9.9M |
| Qube Research & Technologies Ltd | 0.01% | New | 378,740 | $9.5M |
| TD Asset Management Inc | 0.01% | Reduce -19.4% | 376,344 | $9.4M |
| Royce & Associates LP | 0.09% | Add +46.7% | 362,873 | $9.1M |
| Voloridge Investment Management, LLC | 0.03% | New | 348,279 | $8.7M |
| SummitTX Capital, L.P. | 0.25% | New | 332,708 | $8.3M |
| Rock Springs Capital Management LP | 0.42% | Add +368.0% | 324,015 | $8.1M |
| Saturn V Capital Management LP | 1.30% | Reduce -61.5% | 282,692 | $7.1M |
| Ameriprise Financial Inc. | 0.00% | Add +159.4% | 280,120 | $7.0M |
| Renaissance Technologies | 0.01% | Add +69.7% | 279,300 | $7.0M |
| SG Americas Securities, LLC | 0.01% | Add +1017.7% | 263,625 | $6.6M |
| Nantahala Capital Management, LLC | 0.38% | Reduce -37.1% | 254,803 | $6.4M |
| WCM Investment Management, LLC | 0.01% | New | 257,190 | $6.4M |
| HighMark Wealth Management LLC | 2.41% | Reduce -0.2% | 236,785 | $5.9M |
| Marshall Wace, LLP | 0.01% | Add +90.3% | 216,130 | $5.4M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -19.4% | 211,253 | $5.2M |
| Logos Global Management LP | 0.33% | Reduce -61.9% | 200,000 | $5.0M |
| Fred Alger Management, LLC | 0.02% | Reduce -14.8% | 162,147 | $4.1M |
| Deutsche Bank AG | 0.00% | New | 156,205 | $3.9M |
| Platinum Investment Management Ltd. | 0.90% | Reduce -16.8% | 155,101 | $3.9M |
| Burkehill Global Management, LP | 0.26% | New | 150,000 | $3.8M |
| Trexquant Investment LP | 0.03% | Add +135.2% | 146,523 | $3.7M |
| Blue Owl Capital Holdings LP | 1.09% | Reduce -17.7% | 139,450 | $3.5M |
| Tudor Investment Corporation | 0.02% | Add +110.7% | 121,810 | $3.0M |
| Legal & General Group Plc | 0.00% | Add +3.7% | 105,427 | $2.6M |
| Eagle Health Investments LP | 0.57% | No change | 103,100 | $2.6M |
| Holocene Advisors, LP | 0.01% | New | 101,597 | $2.5M |
| Rhenman & Partners Asset Management AB | 0.23% | New | 100,000 | $2.5M |
| Verition Fund Management LLC | 0.01% | Reduce -17.0% | 94,912 | $2.4M |
| Diadema Partners LP | 1.34% | New | 90,000 | $2.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -7.8% | 87,610 | $2.2M |
| Squarepoint Ops LLC | 0.00% | Add +321.4% | 81,812 | $2.0M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.00% | Reduce -30.0% | 81,525 | $2.0M |
| JPMorgan Chase & Co. | 0.00% | Reduce -66.3% | 81,486 | $2.0M |
| XTX Topco Ltd | 0.05% | New | 79,077 | $2.0M |
| Voleon Capital Management LP | 0.04% | New | 79,074 | $2.0M |
| Spruce Street Capital LP | 0.64% | — | 77,997 | $2.0M |
| Russell Investments Group, Ltd. | 0.00% | Reduce -59.0% | 74,819 | $1.9M |
| Cinctive Capital Management LP | 0.11% | Reduce -21.4% | 72,831 | $1.8M |
| Aquatic Capital Management LLC | 0.05% | New | 69,755 | $1.7M |
| Two Sigma Investments, LP | 0.00% | No change | 57,444 | $1.4M |
| Wellington Management Group LLP | 0.00% | Reduce -39.3% | 50,180 | $1.3M |
| Seven Grand Managers, LLC | 0.10% | New | 50,000 | $1.3M |
| HighVista Strategies LLC | 0.29% | Reduce -29.7% | 44,490 | $1.1M |
| Persistent Asset Partners Ltd | 0.52% | New | 43,266 | $1.1M |
| ADAR1 Capital Management, LLC | 0.07% | Reduce -28.1% | 38,566 | $965K |
| B. Metzler seel. Sohn & Co. AG | 0.01% | New | 38,432 | $961K |
| Gsa Capital Partners LLP | 0.07% | Add +76.5% | 33,104 | $828K |
| Boothbay Fund Management, LLC | 0.02% | Add +52.5% | 32,508 | $813K |
| Voya Investment Management LLC | 0.00% | No change | 29,670 | $742K |
| PSP Research LLC | 0.48% | — | 21,879 | $547K |
| Atom Investors LP | 0.04% | New | 18,347 | $459K |
| Meridian Wealth Partners, LLC | 0.06% | No change | 18,101 | $453K |
"% of holder's portfolio" is CNTA's weight in each manager's 13F, not the share of Centessa Pharmaceuticals Ltd. the manager owns.