Crispr Therapeutics AGCRSP
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 481 institutions reported holding Crispr Therapeutics AG (CRSP) in their 13F filings, up 40 from Q3 2025. 70 opened new positions and 52 sold out. The largest holders were ARK Investment Management ($551.8M), BlackRock, Inc. ($393.7M) and Orbis Allan Gray Ltd ($312.0M). 5 famous investors held it, including Cathie Wood (3.7% of ARK Investment Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Crispr Therapeutics AG
- CUSIP
- H17182108
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 70 | $83.2M |
| Exits | 52 | $54.4M |
All 13F filers, Q3 2025 → Q4 2025: 5,192,247 shares bought and 4,814,359 shares sold, net +377,888 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 481 holders
| ARK Investment Management | 3.66% | Add +7.5% | 10,522,057 | $551.8M |
| BlackRock, Inc. | 0.01% | Add +6.5% | 7,508,178 | $393.7M |
| Orbis Allan Gray Ltd | 1.31% | Add +19.4% | 5,950,145 | $312.0M |
| Capital International Investors | 0.05% | Add +4.3% | 5,892,745 | $309.0M |
| State Street Corp. | 0.01% | Reduce -6.3% | 3,753,440 | $196.8M |
| T. Rowe Price Investment Management, Inc. | 0.11% | Reduce -1.7% | 3,226,595 | $169.2M |
| GSK plc | 21.14% | — | 3,220,627 | $168.9M |
| UBS Group AG | 0.03% | Add +7.9% | 2,524,144 | $132.4M |
| Vanguard Group Inc. | 0.00% | Reduce -4.1% | 2,268,394 | $119.0M |
| Geode Capital Management, LLC | 0.01% | Add +5.0% | 2,249,223 | $118.0M |
| SR One Capital Management, LP | 15.14% | No change | 2,038,763 | $106.9M |
| Sumitomo Mitsui Trust Group, Inc. | 0.06% | Reduce -9.5% | 1,958,111 | $102.7M |
| Amova Asset Management Americas, Inc. | 1.19% | Reduce -9.5% | 1,958,111 | $102.6M |
| FMR LLC | 0.01% | Add +3.6% | 1,953,957 | $102.5M |
| EcoR1 Capital, LLC | 3.34% | No change | 1,389,276 | $72.9M |
| Bank of America Corp. | 0.00% | Reduce -2.4% | 1,096,887 | $57.5M |
| NEA Management Company, LLC | 2.83% | No change | 1,058,570 | $55.5M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +4.5% | 1,030,182 | $54.0M |
| Dimensional Fund Advisors LP | 0.01% | Add +3.4% | 907,107 | $47.6M |
| Loomis Sayles & Co. L P | 0.06% | Reduce -1.1% | 899,331 | $47.2M |
| Susquehanna International Group, LLP | 0.06% | Add +4.9% | 853,971 | $44.8M |
| Northern Trust Corp. | 0.01% | Reduce -3.2% | 755,105 | $39.6M |
| Morgan Stanley | 0.00% | Reduce -52.3% | 667,060 | $35.0M |
| Squarepoint Ops LLC | 0.06% | New | 581,108 | $30.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.5% | 542,954 | $28.5M |
| Norges Bank | 0.00% | — | 490,206 | $25.7M |
| Two Sigma Investments, LP | 0.04% | Reduce -55.0% | 470,621 | $24.7M |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 1.41% | Add +37.6% | 389,519 | $20.4M |
| Wells Fargo & Company | 0.00% | Add +5.2% | 318,878 | $16.7M |
| Bank of New York Mellon Corp | 0.00% | Add +2.1% | 310,954 | $16.3M |
| Ameriprise Financial Inc. | 0.00% | Reduce -4.7% | 297,244 | $15.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +18.0% | 275,632 | $14.5M |
| Citadel Advisors | 0.01% | Add +60.2% | 267,685 | $14.0M |
| Barclays PLC | 0.01% | Reduce -28.5% | 249,988 | $13.1M |
| Vestmark Advisory Solutions, Inc. | 0.18% | Add +4.4% | 249,548 | $13.1M |
| Nuveen, LLC | 0.00% | Add +0.3% | 183,384 | $9.6M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -13.1% | 167,464 | $9.0M |
| LPL Financial LLC | 0.00% | Reduce -19.1% | 170,831 | $9.0M |
| Raymond James Financial Inc. | 0.00% | Add +52.2% | 167,148 | $8.8M |
| Royal Bank of Canada | 0.00% | Reduce -64.5% | 165,565 | $8.7M |
| Two Sigma Advisers, LP | 0.02% | Reduce -71.7% | 162,400 | $8.5M |
| Swiss National Bank | 0.01% | Add +1.5% | 161,500 | $8.5M |
| TD Asset Management Inc | 0.01% | Reduce -9.3% | 158,416 | $8.3M |
| Contrarius Group Holdings Ltd | 0.40% | Reduce -42.1% | 156,605 | $8.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 148,901 | $7.8M |
| Versant Venture Management, LLC | 5.17% | No change | 148,831 | $7.8M |
| Citigroup Inc. | 0.00% | Add +119.4% | 132,693 | $7.0M |
| Marex Group Ltd | 0.07% | Add +3.0% | 127,546 | $6.7M |
| No Street GP LP | 0.44% | New | 125,000 | $6.6M |
| Rhumbline Advisers | 0.01% | Reduce -4.1% | 118,778 | $6.2M |
| Reynders McVeigh Capital Management, LLC | 0.29% | Add +3.1% | 116,514 | $6.1M |
| California Public Employees Retirement System | 0.00% | Add +6.2% | 116,104 | $6.1M |
| Rockefeller Capital Management L.P. | 0.01% | Reduce -24.1% | 112,667 | $5.9M |
| Private Advisor Group, LLC | 0.03% | Reduce -9.2% | 107,259 | $5.6M |
| Algert Global LLC | 0.08% | New | 102,850 | $5.4M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -34.5% | 101,014 | $5.3M |
| Wealth Enhancement Advisory Services, LLC | 0.01% | Add +6.4% | 89,356 | $5.2M |
| Beck Bode, LLC | 0.86% | New | 98,801 | $5.2M |
| Alliancebernstein L.P. | 0.00% | Add +11.6% | 96,357 | $5.1M |
| Capital International Sarl | 0.08% | Reduce -4.9% | 94,769 | $5.0M |
| Baker Chad R | 0.89% | Add +0.1% | 93,270 | $5.0M |
| Group One Trading LLC | 0.15% | Reduce -3.4% | 93,954 | $4.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Reduce -9.6% | 89,708 | $4.7M |
| Legal & General Group Plc | 0.00% | Reduce -4.9% | 87,911 | $4.6M |
| Van Eck Associates Corp. | 0.00% | Add +2.6% | 85,831 | $4.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +11.0% | 84,940 | $4.5M |
| Himension Capital (singapore) Pte. LTD. | 0.27% | Add +16.7% | 84,390 | $4.4M |
| Neo Ivy Capital Management | 0.65% | New | 78,726 | $4.1M |
| California State Teachers Retirement System | 0.00% | Add +4.3% | 78,123 | $4.1M |
| Commonwealth Equity Services, LLC | 0.01% | Add +13.1% | 78,113 | $4.1M |
| Slow Capital, Inc. | 0.48% | Add +4.6% | 76,630 | $4.0M |
| Deutsche Bank AG | 0.00% | Add +8.8% | 70,492 | $3.7M |
| Nwam LLC | 0.19% | Reduce -39.2% | 61,843 | $3.4M |
| Cetera Investment Advisers | 0.00% | Add +0.1% | 63,913 | $3.4M |
| Congress Asset Management Co. | 0.02% | Reduce -7.0% | 63,336 | $3.3M |
| Invesco Ltd. | 0.00% | Reduce -6.9% | 60,796 | $3.2M |
| Osaic Holdings, Inc. | 0.00% | Add +5.9% | 59,211 | $3.1M |
| Jones Financial Companies LLLP | 0.00% | Add +28.6% | 57,489 | $3.0M |
| EverSource Wealth Advisors, LLC | 0.11% | Reduce -41.0% | 57,465 | $3.0M |
| Guggenheim Capital LLC | 0.02% | Reduce -0.8% | 57,021 | $3.0M |
| Envestnet Asset Management Inc. | 0.00% | Reduce -19.6% | 56,572 | $3.0M |
| Green Alpha Advisors, LLC | 2.68% | Add +1.3% | 55,737 | $2.9M |
| Capital International Ltd. | 0.10% | Reduce -9.8% | 55,519 | $2.9M |
| Benjamin Edwards Inc. | 0.03% | Add +0.8% | 54,636 | $2.9M |
| First Trust Advisors LP | 0.00% | New | 54,325 | $2.8M |
| National Bank of Canada | 0.00% | Add +445.0% | 53,525 | $2.8M |
| Stifel Financial Corp. | 0.00% | Add +35.4% | 52,180 | $2.7M |
| Curi Capital, LLC | 0.05% | Reduce -1.7% | 50,591 | $2.7M |
| Lazard Asset Management LLC | 0.00% | Reduce -13.8% | 50,246 | $2.6M |
| State of Wisconsin Investment Board | 0.01% | Reduce -6.8% | 48,172 | $2.5M |
| MetLife Investment Management, LLC | 0.01% | Reduce -0.5% | 48,011 | $2.5M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,745 | $2.4M |
| Cambridge Investment Research Advisors, Inc. | 0.01% | Reduce -4.7% | 44,408 | $2.3M |
| Privium Fund Management B.V. | 0.41% | Add +7.2% | 42,874 | $2.2M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -1.1% | 41,530 | $2.2M |
| Palo Alto Investors LP | 0.30% | No change | 41,226 | $2.2M |
| Qsemble Capital Management, LP | 0.18% | New | 40,586 | $2.1M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +0.2% | 40,338 | $2.1M |
| Tudor Investment Corporation | 0.01% | New | 39,468 | $2.1M |
| Wealth Enhancement Trust Services, Inc. | 0.26% | — | 38,753 | $2.0M |
"% of holder's portfolio" is CRSP's weight in each manager's 13F, not the share of Crispr Therapeutics AG the manager owns.