Castle BiosciencesCSTL

13F holders, Q1 2026 (March 31)
186holders −9
24new positions
34sold out
6famous investors
$24.55avg. 13F price*

At the end of Q1 2026, 186 institutions reported holding Castle Biosciences Inc. (CSTL) in their 13F filings, down 9 from Q4 2025. 24 opened new positions and 34 sold out. The largest holders were BlackRock, Inc. ($73.2M), RTW Investments, LP ($67.7M) and Principal Financial Group Inc. ($43.5M). 6 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Castle Biosciences Inc.
CUSIP
14843C105
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200 Q1 2024: 151Q1 2024Q2 2024: 159Q2 2024Q3 2024: 185Q3 2024Q4 2024: 197Q4 2024Q1 2025: 180Q1 2025Q2 2025: 152Q2 2025Q3 2025: 173Q3 2025Q4 2025: 195Q4 2025Q1 2026: 186Q1 2026Q2 2026: 176Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions24$10.3M
Exits34$34.1M

All 13F filers, Q4 2025 → Q1 2026: 3,356,533 shares bought and 3,073,156 shares sold, net +283,377 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 186 holders

BlackRock, Inc. 0.00% Reduce -3.9% 2,982,946 $73.2M
RTW Investments, LP 0.67% Add +30.4% 2,758,335 $67.7M
Principal Financial Group Inc. 0.02% Reduce -2.1% 1,769,877 $43.5M
Portolan Capital Management, LLC 1.76% Reduce -21.9% 1,350,283 $33.1M
Vanguard Capital Management LLC 0.00% — 1,177,522 $28.9M
Dimensional Fund Advisors LP 0.01% Reduce -9.1% 1,039,761 $25.5M
Summit Partners Public Asset Management, LLC 1.07% Reduce -11.2% 940,685 $23.1M
Vanguard Portfolio Management LLC 0.00% — 861,771 $21.2M
Allianz Asset Management GmbH 0.02% Add +30.4% 811,324 $19.9M
State Street Corp. 0.00% Add +4.4% 769,079 $18.9M
Geode Capital Management, LLC 0.00% Add +1.8% 728,100 $17.9M
AIGH Capital Management LLC 2.97% Reduce -5.5% 590,601 $14.5M
Qube Research & Technologies Ltd 0.02% Add +137.6% 559,583 $13.7M
Palisade Capital Management, LP 0.47% Reduce -5.6% 535,884 $13.2M
Renaissance Technologies 0.02% Add +8.1% 532,800 $13.1M
Nuveen, LLC 0.00% Reduce -0.5% 522,127 $12.8M
Acadian Asset Management LLC 0.02% Add +24.1% 484,441 $11.9M
Wasatch Advisors LP 0.07% Reduce -15.3% 455,036 $11.2M
Morgan Stanley 0.00% Add +110.7% 428,934 $10.5M
Eventide Asset Management, LLC 0.16% Add +26.7% 386,425 $9.5M
Connor, Clark & Lunn Investment Management Ltd. 0.02% Reduce -2.9% 377,082 $9.3M
Millennium Management 0.01% Add +14.4% 353,319 $8.7M
Goldman Sachs Group Inc. 0.00% Add +18.8% 341,171 $8.4M
Schroder Investment Management Group 0.01% Reduce -39.3% 298,941 $7.0M
Northern Trust Corp. 0.00% Add +4.1% 273,101 $6.7M
Silvercrest Asset Management Group LLC 0.05% Add +31.0% 268,535 $6.6M
Kornitzer Capital Management Inc. 0.14% Reduce -1.3% 264,396 $6.5M
Bridgeway Capital Management, LLC 0.13% Add +3.4% 255,184 $6.3M
Two Sigma Investments, LP 0.01% Add +196.0% 248,840 $6.1M
Advisors Capital Management, LLC 0.07% Reduce -0.9% 248,376 $6.1M
SG Americas Securities, LLC 0.01% Add +1051.8% 244,886 $6.0M
Charles Schwab Investment Management Inc. 0.00% Reduce -0.3% 241,880 $5.9M
New York State Common Retirement Fund 0.01% No change 233,046 $5.7M
Tudor Investment Corporation 0.03% Add +33.4% 222,982 $5.5M
Panagora Asset Management Inc. 0.02% Add +383.4% 222,353 $5.5M
D. E. Shaw & Co. 0.00% Add +32.7% 211,966 $5.2M
Vanguard Fiduciary Trust Co. 0.00% — 188,211 $4.6M
Allspring Global Investments Holdings, LLC 0.01% Add +0.9% 160,663 $3.9M
Campbell & CO Investment Adviser LLC 0.21% New 148,824 $3.7M
Empowered Funds, LLC 0.02% Add +8.4% 132,184 $3.2M
Trexquant Investment LP 0.02% Add +101.9% 130,434 $3.2M
Parkman Healthcare Partners LLC 0.32% Reduce -16.2% 126,150 $3.1M
BNP Paribas Financial Markets 0.00% Reduce -18.6% 122,156 $3.0M
Citadel Advisors 0.00% Reduce -67.0% 120,977 $3.0M
Franklin Resources Inc. 0.00% Add +12.8% 90,909 $2.2M
Bank of New York Mellon Corp 0.00% Add +1.9% 88,654 $2.2M
JPMorgan Chase & Co. 0.00% Reduce -1.4% 88,771 $2.1M
American Century Companies Inc. 0.00% Add +1.7% 79,107 $1.9M
Orion Porfolio Solutions, LLC 0.02% Add +0.3% 74,896 $1.8M
Mackenzie Financial Corp. 0.00% Add +98.6% 74,111 $1.8M
Bank of America Corp. 0.00% Reduce -74.2% 67,810 $1.7M
SummitTX Capital, L.P. 0.05% Add +285.0% 67,033 $1.6M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -6.7% 64,964 $1.6M
AQR Capital Management 0.00% Add +1.6% 64,880 $1.6M
Envestnet Asset Management Inc. 0.00% Reduce -0.2% 61,865 $1.5M
Invesco Ltd. 0.00% Reduce -55.0% 61,012 $1.5M
Swiss National Bank 0.00% No change 57,300 $1.4M
FMR LLC 0.00% Add +19.2% 50,412 $1.2M
UBS Group AG 0.00% Reduce -65.3% 49,163 $1.2M
Man Group plc 0.00% Add +306.9% 47,138 $1.2M
Formula Growth Ltd. 0.51% New 46,000 $1.1M
Quantinno Capital Management LP 0.00% Add +387.3% 45,476 $1.1M
Jane Street Group, LLC 0.00% Reduce -74.8% 42,562 $1.0M
Schonfeld Strategic Advisors LLC 0.01% Add +97.5% 42,413 $1.0M
Alliancebernstein L.P. 0.00% No change 25,270 $983K
Rhumbline Advisers 0.00% Reduce -0.2% 38,378 $942K
T. Rowe Price Associates Inc. 0.00% Add +10.7% 37,792 $928K
KBC Group NV 0.00% New 36,932 $907K
Nomura Holdings Inc. 0.01% New 35,748 $878K
Sei Investments Co. 0.00% Reduce -11.8% 35,046 $860K
Algert Global LLC 0.01% Add +83.3% 34,778 $854K
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +17.1% 34,387 $844K
ExodusPoint Capital Management, LP 0.01% New 32,608 $801K
Corient Private Wealth LP 0.00% New 31,870 $782K
California State Teachers Retirement System 0.00% Reduce -0.8% 27,513 $675K
Arrowstreet Capital, Limited Partnership 0.00% Add +286.1% 27,142 $666K
Barclays PLC 0.00% Reduce -62.8% 26,810 $658K
Harbor Capital Advisors, Inc. 0.05% Add +90.7% 25,614 $629K
Fox Run Management, L.L.C. 0.11% Add +19.9% 26,247 $618K
STRS Ohio 0.00% Add +98.4% 25,000 $614K
Deutsche Bank AG 0.00% Add +8.0% 24,164 $593K
Truist Financial Corp. 0.00% Add +0.7% 23,781 $584K
Y-Intercept (Hong Kong) Ltd 0.01% Add +77.4% 23,501 $577K
Magnetar Financial LLC 0.01% New 23,332 $573K
Legal & General Group Plc 0.00% Reduce -22.0% 23,184 $569K
Quantbot Technologies LP 0.02% Add +46836.2% 22,060 $542K
Inspire Investing, LLC 0.03% Add +75.2% 21,045 $517K
XTX Topco Ltd 0.01% Reduce -8.3% 20,283 $498K
Brevan Howard Capital Management LP 0.00% New 18,560 $456K
Engineers Gate Manager LP 0.01% Reduce -20.4% 18,256 $448K
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 17,653 $433K
MetLife Investment Management, LLC 0.00% Add +5.3% 16,722 $411K
First Bank & Trust 0.07% Reduce -1.2% 16,504 $405K
Dynamic Technology Lab Private Ltd 0.06% New 15,913 $391K
HRT Financial LP 0.00% Reduce -66.7% 15,858 $389K
Diversify Wealth Management, LLC 0.01% Add +36.0% 15,760 $382K
Perkins Capital Management Inc. 0.35% Reduce -45.0% 15,415 $378K
Janus Henderson Group PLC 0.00% No change 15,037 $369K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +27.3% 15,028 $369K
Summit Global Investments 0.02% Add +10.9% 13,718 $337K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +3.4% 13,676 $336K
Oak Harvest Investment Services 0.03% No change 13,485 $331K
Parallel Advisors, LLC 0.01% Reduce -4.9% 13,301 $327K
Birchview Capital, LP 0.18% Reduce -84.0% 12,900 $317K
Wells Fargo & Company 0.00% Reduce -62.3% 12,892 $316K
Los Angeles Capital Management LLC 0.00% Reduce -46.1% 12,728 $312K
Creative Planning 0.00% Reduce -22.7% 12,479 $306K
Manufacturers Life Insurance Company, The 0.00% Add +46.5% 12,438 $305K
Jump Financial, LLC 0.01% Add +123.6% 12,300 $302K
Gsa Capital Partners LLP 0.02% New 12,236 $300K
Vanguard Global Advisers, LLC 0.00% — 11,502 $282K
Canada Pension Plan Investment Board 0.00% Add +81.0% 11,400 $280K
Jackson Creek Investment Advisors LLC 0.08% Reduce -0.2% 11,214 $275K
Graham Capital Management, L.P. 0.01% Add +1.9% 11,133 $273K
TritonPoint Partners, LLC 0.10% No change 10,777 $265K
Lido Advisors, LLC 0.00% Reduce -0.1% 10,031 $246K
Green Alpha Advisors, LLC 0.24% Reduce -2.8% 9,945 $244K
LPL Financial LLC 0.00% Reduce -10.8% 9,700 $238K
State of Wyoming 0.03% Add +215.9% 9,522 $234K
Susquehanna International Group, LLP 0.00% New 9,520 $234K
Russell Investments Group, Ltd. 0.00% Add +274.4% 9,315 $229K
Cetera Investment Advisers 0.00% Add +3.1% 9,208 $226K
Simon Quick Advisors, LLC 0.01% No change 8,561 $210K
Numerai GP LLC 0.02% New 8,307 $204K
Glenmede Trust Co. NA 0.00% Reduce -0.3% 8,168 $201K
Police & Firemen's Retirement System of New Jersey 0.00% No change 7,829 $192K
Vanguard Investments Australia, Ltd. 0.00% — 7,553 $185K
KLP Kapitalforvaltning As 0.00% No change 6,200 $152K
Assetmark, Inc. 0.00% Add +9.3% 5,779 $142K
China Universal Asset Management Co., Ltd. 0.01% Add +10.9% 5,276 $130K
Citigroup Inc. 0.00% Reduce -87.6% 4,027 $99K
Globeflex Capital L P 0.01% No change 3,759 $92K
CANADA LIFE ASSURANCE Co 0.00% No change 3,244 $80K
Harbour Investments, Inc. 0.00% Add +3.5% 3,248 $80K
Cwm, LLC 0.00% Add +30.8% 3,010 $74K
Farther Finance Advisors, LLC 0.00% Reduce -28.4% 2,388 $60K
Ameritas Investment Partners, Inc. 0.00% No change 2,373 $58K
Tower Research Capital LLC (TRC) 0.00% Reduce -20.3% 1,604 $39K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +9.4% 1,551 $38K
State of Alaska, Department of Revenue 0.00% No change 1,553 $38K
Federated Hermes, Inc. 0.00% Add +89.2% 1,249 $31K
Covestor Ltd 0.02% Add +9.8% 1,096 $27K
Sterling Capital Management LLC 0.00% Reduce -40.7% 971 $24K
Osaic Holdings, Inc. 0.00% Reduce -97.7% 857 $21K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Reduce -58.6% 761 $19K
GF Fund Management Co. LTD. 0.00% Add +13.1% 648 $16K
First Horizon Corp. 0.00% Reduce -13.4% 587 $14K
Hughes Financial Services, LLC 0.00% Add +2.3% 446 $11K
Rossby Financial, LCC 0.00% No change 429 $11K
Rockefeller Capital Management L.P. 0.00% Add +397.7% 433 $11K
Meeder Asset Management Inc. 0.00% New 387 $10K
Quadrant Capital Group LLC 0.00% No change 336 $8K
Group One Trading LLC 0.00% New 292 $7K
Advisory Services Network, LLC 0.00% New 287 $7K
Nisa Investment Advisors, LLC 0.00% Reduce -8.9% 256 $6K
Versant Capital Management, Inc 0.00% Add +35.9% 246 $6K
Jones Financial Companies LLLP 0.00% Reduce -51.5% 250 $6K
MassMutual Private Wealth & Trust, FSB 0.00% New 202 $5K
PNC Financial Services Group, Inc. 0.00% Reduce -70.2% 163 $4K
Royal Bank of Canada 0.00% Reduce -79.5% 177 $4K
Huntington National Bank 0.00% No change 139 $3K
Essential Partners LLC 0.00% Reduce -3.7% 129 $3K
US Bancorp \de 0.00% Add +91.7% 92 $2K
Bfsg, LLC 0.00% No change 90 $2K
Destiny Wealth Partners, LLC 0.00% New 88 $2K
Allworth Financial LP 0.00% Add +110.0% 63 $2K
Rothschild Investment LLC 0.00% Add +9.4% 58 $1K
IFP Advisors, Inc 0.00% No change 52 $1K
Spire Wealth Management 0.00% No change 50 $1K
SBI Securities Co., Ltd. 0.00% Reduce -9.6% 47 $1K
GAMMA Investing LLC 0.00% Reduce -11.5% 46 $1K
Signaturefd, LLC 0.00% No change 45 $1K
Parkside Financial Bank & Trust 0.00% No change 25 $614
EverSource Wealth Advisors, LLC 0.00% Reduce -28.6% 20 $491
SJS Investment Consulting Inc. 0.00% New 19 $467
MAI Capital Management 0.00% New 19 $467
Missouri Trust & Investment Co 0.00% No change 19 $466
Signature Equity Partners, LLC 0.00% No change 16 $393
Investors Portfolio Services LLC 0.00% New 18 $325
Smartleaf Asset Management LLC 0.00% New 8 $207
Arax Advisory Partners 0.00% Reduce -89.2% 4 $99
Wealth Preservation Advisors, LLC 0.00% New 4 $98
Sunbelt Securities, Inc. 0.00% Add +200.0% 3 $74
True Wealth Design, LLC 0.00% Reduce -60.0% 2 $50
Larson Financial Group LLC 0.00% No change 1 $25
Twin Peaks Wealth Advisors, LLC 0.00% New 1 $25

"% of holder's portfolio" is CSTL's weight in each manager's 13F, not the share of Castle Biosciences Inc. the manager owns.