Edgewise TherapeuticsEWTX
13F holders, Q4 2024 (December 31)At the end of Q4 2024, 200 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, up 23 from Q3 2024. 35 opened new positions and 19 sold out. The largest holders were Orbimed Advisors LLC ($401.1M), Ra Capital Management, L.P. ($237.9M) and BlackRock, Inc. ($173.0M). 8 famous investors held it, including Andreas Halvorsen (0.1% of Viking Global Investors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Edgewise Therapeutics Inc.
- CUSIP
- 28036F105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 35 | $84.1M |
| Exits | 19 | $126.6M |
All 13F filers, Q3 2024 → Q4 2024: 9,277,888 shares bought and 12,188,373 shares sold, net −2,910,485 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 200 holders
| Orbimed Advisors LLC | 8.33% | No change | 15,021,721 | $401.1M |
| Ra Capital Management, L.P. | 3.17% | No change | 8,909,091 | $237.9M |
| BlackRock, Inc. | 0.00% | Add +1.3% | 6,479,015 | $173.0M |
| Baker Bros. Advisors LP | 1.78% | Add +5.4% | 6,155,940 | $164.4M |
| Novo Holdings A/S | 8.08% | Reduce -9.9% | 5,000,000 | $133.5M |
| Janus Henderson Group PLC | 0.07% | Add +9.3% | 4,983,940 | $133.0M |
| Paradigm Biocapital Advisors LP | 4.17% | Add +61.1% | 4,493,929 | $120.0M |
| Vanguard Group Inc. | 0.00% | Reduce -1.1% | 4,466,849 | $119.3M |
| Cormorant Asset Management, LP | 5.00% | No change | 3,406,534 | $91.0M |
| Perceptive Advisors LLC | 2.00% | Add +15.2% | 2,685,537 | $71.7M |
| Braidwell LP | 2.78% | Add +19.1% | 2,332,196 | $62.3M |
| Deerfield Management Company, L.P. | 1.19% | Add +16.7% | 2,078,509 | $55.5M |
| State Street Corp. | 0.00% | Add +1.8% | 1,715,545 | $45.8M |
| Geode Capital Management, LLC | 0.00% | Add +0.1% | 1,600,571 | $42.7M |
| Driehaus Capital Management LLC | 0.33% | Reduce -23.5% | 1,493,791 | $39.9M |
| Bellevue Group AG | 0.73% | No change | 1,428,929 | $38.2M |
| Frazier Life Sciences Management, L.P. | 1.41% | Reduce -55.1% | 1,271,245 | $33.9M |
| Viking Global Investors | 0.11% | Reduce -17.3% | 1,224,986 | $32.7M |
| MPM Bioimpact LLC | 4.09% | Add +17.7% | 1,079,316 | $28.8M |
| Artisan Partners Limited Partnership | 0.04% | Add +7.1% | 1,071,596 | $28.6M |
| New Leaf Venture Partners, L.L.C. | 36.77% | Reduce -33.7% | 1,030,161 | $27.5M |
| Millennium Management | 0.02% | Reduce -9.9% | 888,968 | $23.7M |
| First Light Asset Management, LLC | 1.99% | New | 780,639 | $20.8M |
| American Century Companies Inc. | 0.01% | Reduce -17.6% | 770,353 | $20.6M |
| Siren, L.L.C. | 0.87% | Add +81.7% | 734,343 | $19.6M |
| Dimensional Fund Advisors LP | 0.00% | Add +0.4% | 729,923 | $19.5M |
| Deep Track Capital, LP | 0.71% | Reduce -35.5% | 710,421 | $19.0M |
| D. E. Shaw & Co. | 0.02% | Add +50.7% | 686,371 | $18.3M |
| Northern Trust Corp. | 0.00% | Add +6.2% | 611,306 | $16.3M |
| Foresite Capital Management VI LLC | 6.96% | — | 585,000 | $15.6M |
| Woodline Partners LP | 0.10% | Add +7.5% | 567,218 | $15.1M |
| Integral Health Asset Management, LLC | 1.30% | New | 550,000 | $14.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.9% | 537,359 | $14.3M |
| Opaleye Management Inc. | 2.29% | Reduce -8.1% | 480,000 | $12.8M |
| Citadel Advisors | 0.01% | Reduce -12.8% | 469,451 | $12.5M |
| Morgan Stanley | 0.00% | Add +4.4% | 436,430 | $11.7M |
| Nuveen Asset Management, LLC | 0.00% | Add +58.6% | 428,858 | $11.5M |
| Sofinnova Investments, Inc. | 0.79% | Add +4.7% | 402,773 | $10.8M |
| Logos Global Management LP | 1.25% | Reduce -11.1% | 400,000 | $10.7M |
| Parkman Healthcare Partners LLC | 1.36% | Reduce -42.0% | 381,173 | $10.2M |
| Qube Research & Technologies Ltd | 0.02% | Add +180.1% | 369,442 | $9.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -28.1% | 346,891 | $9.3M |
| Amundi | 0.00% | Add +127.2% | 341,687 | $8.7M |
| Pictet Asset Management Holding SA | 0.01% | New | 301,241 | $8.0M |
| Granahan Investment Management, LLC | 0.33% | Reduce -41.4% | 300,013 | $8.0M |
| Tang Capital Management LLC | 0.53% | New | 300,000 | $8.0M |
| Voya Investment Management LLC | 0.01% | Reduce -7.7% | 284,148 | $7.6M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +231.1% | 279,125 | $7.5M |
| Deutsche Bank AG | 0.00% | Add +26.6% | 275,837 | $7.4M |
| Schonfeld Strategic Advisors LLC | 0.05% | Reduce -50.8% | 268,509 | $7.2M |
| Candriam S.C.A. | 0.04% | Reduce -13.8% | 253,965 | $6.8M |
| FMR LLC | 0.00% | Reduce -62.0% | 248,036 | $6.6M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Add +1015.8% | 240,000 | $6.4M |
| Kennedy Capital Management LLC | 0.14% | Add +4.2% | 236,642 | $6.3M |
| Cubist Systematic Strategies, LLC | 0.10% | New | 219,549 | $5.9M |
| Bank of New York Mellon Corp | 0.00% | Add +0.1% | 211,056 | $5.6M |
| Wellington Management Group LLP | 0.00% | Reduce -1.2% | 202,893 | $5.4M |
| Walleye Capital LLC | 0.06% | Reduce -18.0% | 198,662 | $5.3M |
| Moody Aldrich Partners LLC | 0.93% | Add +24.3% | 187,932 | $5.0M |
| DAFNA Capital Management LLC | 1.28% | Reduce -17.9% | 187,140 | $5.0M |
| Soleus Capital Management, L.P. | 0.37% | New | 183,300 | $4.9M |
| Aberdeen Group plc | 0.01% | Reduce -30.6% | 178,043 | $4.8M |
| Barclays PLC | 0.00% | Add +12.0% | 133,657 | $3.6M |
| Stempoint Capital LP | 0.89% | Add +566.9% | 132,706 | $3.5M |
| Two Sigma Investments, LP | 0.01% | Reduce -49.6% | 131,667 | $3.5M |
| JPMorgan Chase & Co. | 0.00% | Reduce -21.5% | 124,435 | $3.3M |
| Algert Global LLC | 0.07% | Add +1073.0% | 110,259 | $2.9M |
| J. Goldman & Co LP | 0.10% | Add +835.6% | 107,278 | $2.9M |
| Point72 Asset Management | 0.01% | New | 106,562 | $2.8M |
| Rhumbline Advisers | 0.00% | Add +1.5% | 102,397 | $2.7M |
| Schroder Investment Management Group | 0.00% | New | 93,061 | $2.5M |
| UBS Group AG | 0.00% | Add +22.3% | 92,066 | $2.5M |
| Informed Momentum Co LLC | 0.35% | Reduce -27.0% | 91,333 | $2.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | — | 90,031 | $2.4M |
| Acuta Capital Partners, LLC | 2.35% | Add +39.1% | 87,658 | $2.3M |
| Ally Bridge Group (NY) LLC | 1.90% | Reduce -55.7% | 83,176 | $2.2M |
| HighVista Strategies LLC | 0.82% | Reduce -6.9% | 82,732 | $2.2M |
| Exome Asset Management LLC | 1.64% | Add +36.0% | 81,473 | $2.2M |
| Ensign Peak Advisors, Inc | 0.00% | New | 80,509 | $2.1M |
| Harvest Investment Services, LLC | 0.52% | New | 79,381 | $2.1M |
| Citigroup Inc. | 0.00% | Add +3.5% | 78,497 | $2.1M |
| Alliancebernstein L.P. | 0.00% | Add +1.7% | 77,260 | $2.1M |
| Alps Advisors Inc. | 0.01% | Add +11.1% | 76,567 | $2.0M |
| Trexquant Investment LP | 0.02% | New | 74,781 | $2.0M |
| Bridger Management, LLC | 1.07% | No change | 74,700 | $2.0M |
| Swiss National Bank | 0.00% | No change | 73,600 | $2.0M |
| Quantum Private Wealth, LLC | 0.63% | Add +0.1% | 73,524 | $2.0M |
| New York State Common Retirement Fund | 0.00% | Add +6.4% | 71,366 | $1.9M |
| Polar Asset Management Partners Inc. | 0.03% | Reduce -59.2% | 64,279 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Reduce -14.3% | 61,521 | $1.6M |
| Baron Capital (BAMCO) | 0.00% | New | 60,000 | $1.6M |
| Jump Financial, LLC | 0.03% | Reduce -58.1% | 55,178 | $1.5M |
| Sei Investments Co. | 0.00% | Reduce -0.8% | 52,178 | $1.4M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 80,000 | $1.4M |
| Legal & General Group Plc | 0.00% | Add +15.2% | 50,292 | $1.3M |
| Simplex Trading, LLC | 0.04% | Reduce -32.3% | 50,130 | $1.3M |
| Bank of America Corp. | 0.00% | Reduce -84.1% | 48,907 | $1.3M |
| Norges Bank | 0.00% | No change | 47,755 | $1.3M |
| Verition Fund Management LLC | 0.01% | New | 46,391 | $1.2M |
| MetLife Investment Management, LLC | 0.01% | Add +5.5% | 44,612 | $1.2M |
| Tudor Investment Corporation | 0.01% | Add +23.0% | 43,809 | $1.2M |
| Invesco Ltd. | 0.00% | Reduce -33.0% | 43,435 | $1.2M |
| EFG Asset Management (North America) Corp. | 0.15% | New | 41,338 | $1.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.0% | 41,313 | $1.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +4.6% | 40,170 | $1.1M |
| California State Teachers Retirement System | 0.00% | Reduce -0.8% | 37,638 | $1.0M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.0% | 36,090 | $964K |
| Intech Investment Management LLC | 0.01% | Add +75.1% | 34,844 | $930K |
| Wells Fargo & Company | 0.00% | Add +51.7% | 33,918 | $906K |
| Prelude Capital Management, LLC | 0.07% | Add +13.2% | 33,164 | $885K |
| BNP Paribas Financial Markets | 0.00% | New | 33,082 | $883K |
| Russell Investments Group, Ltd. | 0.00% | New | 33,079 | $883K |
| Susquehanna International Group, LLP | 0.00% | Reduce -84.2% | 31,713 | $847K |
| Franklin Resources Inc. | 0.00% | Reduce -30.1% | 31,607 | $844K |
| Jane Street Group, LLC | 0.00% | Reduce -39.3% | 30,558 | $816K |
| Marshall Wace, LLP | 0.00% | Reduce -94.8% | 29,893 | $798K |
| T. Rowe Price Associates Inc. | 0.00% | Add +22.0% | 29,050 | $776K |
| Squarepoint Ops LLC | 0.00% | Add +58.5% | 26,358 | $704K |
| Brevan Howard Capital Management LP | 0.02% | Add +125.3% | 25,346 | $677K |
| ProShare Advisors LLC | 0.00% | Add +29.4% | 24,928 | $666K |
| Balyasny Asset Management L.P. | 0.00% | New | 23,364 | $624K |
| Ameriprise Financial Inc. | 0.00% | New | 22,584 | $603K |
| Glenmede Trust Co. NA | 0.00% | Add +21.2% | 21,919 | $585K |
| Handelsbanken Fonder AB | 0.00% | New | 21,800 | $582K |
| Victory Capital Management Inc. | 0.00% | New | 21,568 | $576K |
| Readystate Asset Management LP | 0.04% | New | 21,362 | $570K |
| China Universal Asset Management Co., Ltd. | 0.05% | Add +11.3% | 20,077 | $536K |
| Graham Capital Management, L.P. | 0.02% | Add +15.8% | 18,415 | $492K |
| Persistent Asset Partners Ltd | 0.40% | — | 16,593 | $465K |
| HRT Financial LP | 0.00% | Reduce -82.3% | 17,113 | $456K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 16,870 | $450K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 15,453 | $413K |
| Profund Advisors LLC | 0.01% | Reduce -2.0% | 14,945 | $399K |
| Envestnet Asset Management Inc. | 0.00% | Add +32.0% | 14,678 | $392K |
| Cinctive Capital Management LP | 0.02% | Reduce -69.5% | 14,093 | $376K |
| Nantahala Capital Management, LLC | 0.03% | No change | 13,371 | $357K |
| Crestline Management, L.P. | 0.01% | Reduce -50.8% | 13,268 | $354K |
| Optimize Financial Inc. | 0.24% | — | 12,062 | $322K |
| Orion Porfolio Solutions, LLC | 0.00% | Reduce -8.3% | 11,928 | $318K |
| Orion Portfolio Solutions, LLC | 0.00% | Reduce -8.3% | 11,928 | $318K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -10.1% | 11,906 | $318K |
| Gsa Capital Partners LLP | 0.02% | New | 11,593 | $310K |
| Teacher Retirement System of Texas | 0.00% | Add +18.9% | 11,143 | $298K |
| Arizona State Retirement System | 0.00% | Add +1.0% | 10,863 | $290K |
| HSBC Holdings PLC | 0.00% | Add +23.3% | 10,759 | $283K |
| AlphaCentric Advisors LLC | 0.27% | New | 10,316 | $275K |
| Bleakley Financial Group, LLC | 0.01% | Add +1.8% | 10,080 | $269K |
| Sfmg, LLC | 0.02% | No change | 10,000 | $267K |
| Neo Ivy Capital Management | 0.05% | New | 9,720 | $259K |
| AQR Capital Management | 0.00% | Add +4.7% | 9,366 | $250K |
| BI Asset Management Fondsmaeglerselskab A/S | 0.00% | New | 8,853 | $236K |
| STRS Ohio | 0.00% | Reduce -12.8% | 8,200 | $219K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -3.3% | 7,891 | $211K |
| Jain Global LLC | 0.01% | — | 7,850 | $210K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +6.8% | 7,594 | $203K |
| Point72 (DIFC) Ltd | 0.02% | New | 6,889 | $184K |
| KLP Kapitalforvaltning As | 0.00% | — | 6,800 | $182K |
| Quantbot Technologies LP | 0.00% | New | 3,855 | $103K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1097.4% | 3,676 | $98K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -7.0% | 3,155 | $91K |
| Royal Bank of Canada | 0.00% | Reduce -62.7% | 3,324 | $89K |
| US Bancorp \de | 0.00% | Reduce -61.2% | 3,309 | $88K |
| Meeder Asset Management Inc. | 0.01% | No change | 3,307 | $88K |
| Aquatic Capital Management LLC | 0.00% | New | 2,894 | $77K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 2,849 | $76K |
| Virtus Advisers, LLC | 0.03% | Reduce -50.9% | 2,526 | $67K |
| Amalgamated Bank | 0.00% | No change | 2,512 | $67K |
| AlphaQuest LLC | 0.01% | Reduce -75.6% | 2,203 | $59K |
| Caitong International Asset Management Co., Ltd | 0.05% | — | 2,053 | $55K |
| Quarry LP | 0.01% | Reduce -42.9% | 2,000 | $53K |
| GF Fund Management Co. LTD. | 0.00% | — | 1,988 | $53K |
| Diadema Partners LP | 0.04% | — | 1,359 | $36K |
| GAMMA Investing LLC | 0.00% | Add +2.6% | 1,321 | $35K |
| Osaic Holdings, Inc. | 0.00% | Add +18.5% | 1,064 | $28K |
| Nisa Investment Advisors, LLC | 0.00% | Add +6.8% | 1,049 | $28K |
| Group One Trading LLC | 0.00% | New | 476 | $13K |
| Signaturefd, LLC | 0.00% | Reduce -13.2% | 466 | $12K |
| Daiwa Securities Group Inc. | 0.00% | No change | 344 | $9K |
| Lindbrook Capital, LLC | 0.00% | No change | 325 | $9K |
| Bfsg, LLC | 0.00% | Reduce -50.0% | 300 | $8K |
| SBI Securities Co., Ltd. | 0.00% | — | 243 | $6K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 229 | $6K |
| HighMark Wealth Management LLC | 0.00% | New | 165 | $4K |
| Fortitude Family Office, LLC | 0.00% | No change | 160 | $4K |
| Parallel Advisors, LLC | 0.00% | Add +2.3% | 136 | $4K |
| Comerica Bank | 0.00% | New | 108 | $3K |
| Federated Hermes, Inc. | 0.00% | Reduce -1.8% | 107 | $3K |
| Rothschild Investment LLC | 0.00% | Add +28.6% | 90 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -23.5% | 75 | $2K |
| Sterling Capital Management LLC | 0.00% | No change | 75 | $2K |
| Versant Capital Management, Inc | 0.00% | No change | 40 | $1K |
| Cwm, LLC | 0.00% | Add +30.0% | 26 | $1K |
| Principal Securities, Inc. | 0.00% | No change | 27 | $721 |
| Smartleaf Asset Management LLC | 0.00% | Reduce -72.4% | 21 | $568 |
| EverSource Wealth Advisors, LLC | 0.00% | New | 18 | $480 |
| NewEdge Advisors, LLC | 0.00% | No change | 9 | $240 |
| Farther Finance Advisors, LLC | 0.00% | No change | 8 | $214 |
| National Bank of Canada | 0.00% | Add +200.0% | 3 | $80 |
| Global Retirement Partners, LLC | 0.00% | Reduce -93.6% | 3 | $80 |
| Covestor Ltd | 0.00% | Reduce -28.6% | 5 | $0 |
"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.