Edgewise TherapeuticsEWTX

13F holders, Q4 2024 (December 31)
200holders +23
35new positions
19sold out
8famous investors
$26.69avg. 13F price*

At the end of Q4 2024, 200 institutions reported holding Edgewise Therapeutics Inc. (EWTX) in their 13F filings, up 23 from Q3 2024. 35 opened new positions and 19 sold out. The largest holders were Orbimed Advisors LLC ($401.1M), Ra Capital Management, L.P. ($237.9M) and BlackRock, Inc. ($173.0M). 8 famous investors held it, including Andreas Halvorsen (0.1% of Viking Global Investors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Edgewise Therapeutics Inc.
CUSIP
28036F105
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 129Q1 2024Q2 2024: 140Q2 2024Q3 2024: 177Q3 2024Q4 2024: 200Q4 2024Q1 2025: 192Q1 2025Q2 2025: 178Q2 2025Q3 2025: 173Q3 2025Q4 2025: 199Q4 2025Q1 2026: 214Q1 2026Q2 2026: 226Q2 2026

Total Exit/New Position Q3 2024 → Q4 2024

InstitutionsTotal Value
New Positions35$84.1M
Exits19$126.6M

All 13F filers, Q3 2024 → Q4 2024: 9,277,888 shares bought and 12,188,373 shares sold, net −2,910,485 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 200 holders

Orbimed Advisors LLC 8.33% No change 15,021,721 $401.1M
Ra Capital Management, L.P. 3.17% No change 8,909,091 $237.9M
BlackRock, Inc. 0.00% Add +1.3% 6,479,015 $173.0M
Baker Bros. Advisors LP 1.78% Add +5.4% 6,155,940 $164.4M
Novo Holdings A/S 8.08% Reduce -9.9% 5,000,000 $133.5M
Janus Henderson Group PLC 0.07% Add +9.3% 4,983,940 $133.0M
Paradigm Biocapital Advisors LP 4.17% Add +61.1% 4,493,929 $120.0M
Vanguard Group Inc. 0.00% Reduce -1.1% 4,466,849 $119.3M
Cormorant Asset Management, LP 5.00% No change 3,406,534 $91.0M
Perceptive Advisors LLC 2.00% Add +15.2% 2,685,537 $71.7M
Braidwell LP 2.78% Add +19.1% 2,332,196 $62.3M
Deerfield Management Company, L.P. 1.19% Add +16.7% 2,078,509 $55.5M
State Street Corp. 0.00% Add +1.8% 1,715,545 $45.8M
Geode Capital Management, LLC 0.00% Add +0.1% 1,600,571 $42.7M
Driehaus Capital Management LLC 0.33% Reduce -23.5% 1,493,791 $39.9M
Bellevue Group AG 0.73% No change 1,428,929 $38.2M
Frazier Life Sciences Management, L.P. 1.41% Reduce -55.1% 1,271,245 $33.9M
Viking Global Investors 0.11% Reduce -17.3% 1,224,986 $32.7M
MPM Bioimpact LLC 4.09% Add +17.7% 1,079,316 $28.8M
Artisan Partners Limited Partnership 0.04% Add +7.1% 1,071,596 $28.6M
New Leaf Venture Partners, L.L.C. 36.77% Reduce -33.7% 1,030,161 $27.5M
Millennium Management 0.02% Reduce -9.9% 888,968 $23.7M
First Light Asset Management, LLC 1.99% New 780,639 $20.8M
American Century Companies Inc. 0.01% Reduce -17.6% 770,353 $20.6M
Siren, L.L.C. 0.87% Add +81.7% 734,343 $19.6M
Dimensional Fund Advisors LP 0.00% Add +0.4% 729,923 $19.5M
Deep Track Capital, LP 0.71% Reduce -35.5% 710,421 $19.0M
D. E. Shaw & Co. 0.02% Add +50.7% 686,371 $18.3M
Northern Trust Corp. 0.00% Add +6.2% 611,306 $16.3M
Foresite Capital Management VI LLC 6.96% — 585,000 $15.6M
Woodline Partners LP 0.10% Add +7.5% 567,218 $15.1M
Integral Health Asset Management, LLC 1.30% New 550,000 $14.7M
Charles Schwab Investment Management Inc. 0.00% Add +2.9% 537,359 $14.3M
Opaleye Management Inc. 2.29% Reduce -8.1% 480,000 $12.8M
Citadel Advisors 0.01% Reduce -12.8% 469,451 $12.5M
Morgan Stanley 0.00% Add +4.4% 436,430 $11.7M
Nuveen Asset Management, LLC 0.00% Add +58.6% 428,858 $11.5M
Sofinnova Investments, Inc. 0.79% Add +4.7% 402,773 $10.8M
Logos Global Management LP 1.25% Reduce -11.1% 400,000 $10.7M
Parkman Healthcare Partners LLC 1.36% Reduce -42.0% 381,173 $10.2M
Qube Research & Technologies Ltd 0.02% Add +180.1% 369,442 $9.9M
Goldman Sachs Group Inc. 0.00% Reduce -28.1% 346,891 $9.3M
Amundi 0.00% Add +127.2% 341,687 $8.7M
Pictet Asset Management Holding SA 0.01% New 301,241 $8.0M
Granahan Investment Management, LLC 0.33% Reduce -41.4% 300,013 $8.0M
Tang Capital Management LLC 0.53% New 300,000 $8.0M
Voya Investment Management LLC 0.01% Reduce -7.7% 284,148 $7.6M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +231.1% 279,125 $7.5M
Deutsche Bank AG 0.00% Add +26.6% 275,837 $7.4M
Schonfeld Strategic Advisors LLC 0.05% Reduce -50.8% 268,509 $7.2M
Candriam S.C.A. 0.04% Reduce -13.8% 253,965 $6.8M
FMR LLC 0.00% Reduce -62.0% 248,036 $6.6M
Adage Capital Partners Gp, L.L.C. 0.01% Add +1015.8% 240,000 $6.4M
Kennedy Capital Management LLC 0.14% Add +4.2% 236,642 $6.3M
Cubist Systematic Strategies, LLC 0.10% New 219,549 $5.9M
Bank of New York Mellon Corp 0.00% Add +0.1% 211,056 $5.6M
Wellington Management Group LLP 0.00% Reduce -1.2% 202,893 $5.4M
Walleye Capital LLC 0.06% Reduce -18.0% 198,662 $5.3M
Moody Aldrich Partners LLC 0.93% Add +24.3% 187,932 $5.0M
DAFNA Capital Management LLC 1.28% Reduce -17.9% 187,140 $5.0M
Soleus Capital Management, L.P. 0.37% New 183,300 $4.9M
Aberdeen Group plc 0.01% Reduce -30.6% 178,043 $4.8M
Barclays PLC 0.00% Add +12.0% 133,657 $3.6M
Stempoint Capital LP 0.89% Add +566.9% 132,706 $3.5M
Two Sigma Investments, LP 0.01% Reduce -49.6% 131,667 $3.5M
JPMorgan Chase & Co. 0.00% Reduce -21.5% 124,435 $3.3M
Algert Global LLC 0.07% Add +1073.0% 110,259 $2.9M
J. Goldman & Co LP 0.10% Add +835.6% 107,278 $2.9M
Point72 Asset Management 0.01% New 106,562 $2.8M
Rhumbline Advisers 0.00% Add +1.5% 102,397 $2.7M
Schroder Investment Management Group 0.00% New 93,061 $2.5M
UBS Group AG 0.00% Add +22.3% 92,066 $2.5M
Informed Momentum Co LLC 0.35% Reduce -27.0% 91,333 $2.4M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% — 90,031 $2.4M
Acuta Capital Partners, LLC 2.35% Add +39.1% 87,658 $2.3M
Ally Bridge Group (NY) LLC 1.90% Reduce -55.7% 83,176 $2.2M
HighVista Strategies LLC 0.82% Reduce -6.9% 82,732 $2.2M
Exome Asset Management LLC 1.64% Add +36.0% 81,473 $2.2M
Ensign Peak Advisors, Inc 0.00% New 80,509 $2.1M
Harvest Investment Services, LLC 0.52% New 79,381 $2.1M
Citigroup Inc. 0.00% Add +3.5% 78,497 $2.1M
Alliancebernstein L.P. 0.00% Add +1.7% 77,260 $2.1M
Alps Advisors Inc. 0.01% Add +11.1% 76,567 $2.0M
Trexquant Investment LP 0.02% New 74,781 $2.0M
Bridger Management, LLC 1.07% No change 74,700 $2.0M
Swiss National Bank 0.00% No change 73,600 $2.0M
Quantum Private Wealth, LLC 0.63% Add +0.1% 73,524 $2.0M
New York State Common Retirement Fund 0.00% Add +6.4% 71,366 $1.9M
Polar Asset Management Partners Inc. 0.03% Reduce -59.2% 64,279 $1.7M
State of Wisconsin Investment Board 0.00% Reduce -14.3% 61,521 $1.6M
Baron Capital (BAMCO) 0.00% New 60,000 $1.6M
Jump Financial, LLC 0.03% Reduce -58.1% 55,178 $1.5M
Sei Investments Co. 0.00% Reduce -0.8% 52,178 $1.4M
DekaBank Deutsche Girozentrale 0.00% No change 80,000 $1.4M
Legal & General Group Plc 0.00% Add +15.2% 50,292 $1.3M
Simplex Trading, LLC 0.04% Reduce -32.3% 50,130 $1.3M
Bank of America Corp. 0.00% Reduce -84.1% 48,907 $1.3M
Norges Bank 0.00% No change 47,755 $1.3M
Verition Fund Management LLC 0.01% New 46,391 $1.2M
MetLife Investment Management, LLC 0.01% Add +5.5% 44,612 $1.2M
Tudor Investment Corporation 0.01% Add +23.0% 43,809 $1.2M
Invesco Ltd. 0.00% Reduce -33.0% 43,435 $1.2M
EFG Asset Management (North America) Corp. 0.15% New 41,338 $1.1M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.0% 41,313 $1.1M
Manufacturers Life Insurance Company, The 0.00% Add +4.6% 40,170 $1.1M
California State Teachers Retirement System 0.00% Reduce -0.8% 37,638 $1.0M
Corebridge Financial, Inc. 0.01% Reduce -7.0% 36,090 $964K
Intech Investment Management LLC 0.01% Add +75.1% 34,844 $930K
Wells Fargo & Company 0.00% Add +51.7% 33,918 $906K
Prelude Capital Management, LLC 0.07% Add +13.2% 33,164 $885K
BNP Paribas Financial Markets 0.00% New 33,082 $883K
Russell Investments Group, Ltd. 0.00% New 33,079 $883K
Susquehanna International Group, LLP 0.00% Reduce -84.2% 31,713 $847K
Franklin Resources Inc. 0.00% Reduce -30.1% 31,607 $844K
Jane Street Group, LLC 0.00% Reduce -39.3% 30,558 $816K
Marshall Wace, LLP 0.00% Reduce -94.8% 29,893 $798K
T. Rowe Price Associates Inc. 0.00% Add +22.0% 29,050 $776K
Squarepoint Ops LLC 0.00% Add +58.5% 26,358 $704K
Brevan Howard Capital Management LP 0.02% Add +125.3% 25,346 $677K
ProShare Advisors LLC 0.00% Add +29.4% 24,928 $666K
Balyasny Asset Management L.P. 0.00% New 23,364 $624K
Ameriprise Financial Inc. 0.00% New 22,584 $603K
Glenmede Trust Co. NA 0.00% Add +21.2% 21,919 $585K
Handelsbanken Fonder AB 0.00% New 21,800 $582K
Victory Capital Management Inc. 0.00% New 21,568 $576K
Readystate Asset Management LP 0.04% New 21,362 $570K
China Universal Asset Management Co., Ltd. 0.05% Add +11.3% 20,077 $536K
Graham Capital Management, L.P. 0.02% Add +15.8% 18,415 $492K
Persistent Asset Partners Ltd 0.40% — 16,593 $465K
HRT Financial LP 0.00% Reduce -82.3% 17,113 $456K
State Board of Administration of Florida Retirement System 0.00% No change 16,870 $450K
Police & Firemen's Retirement System of New Jersey 0.00% — 15,453 $413K
Profund Advisors LLC 0.01% Reduce -2.0% 14,945 $399K
Envestnet Asset Management Inc. 0.00% Add +32.0% 14,678 $392K
Cinctive Capital Management LP 0.02% Reduce -69.5% 14,093 $376K
Nantahala Capital Management, LLC 0.03% No change 13,371 $357K
Crestline Management, L.P. 0.01% Reduce -50.8% 13,268 $354K
Optimize Financial Inc. 0.24% — 12,062 $322K
Orion Porfolio Solutions, LLC 0.00% Reduce -8.3% 11,928 $318K
Orion Portfolio Solutions, LLC 0.00% Reduce -8.3% 11,928 $318K
Rafferty Asset Management, LLC 0.00% Reduce -10.1% 11,906 $318K
Gsa Capital Partners LLP 0.02% New 11,593 $310K
Teacher Retirement System of Texas 0.00% Add +18.9% 11,143 $298K
Arizona State Retirement System 0.00% Add +1.0% 10,863 $290K
HSBC Holdings PLC 0.00% Add +23.3% 10,759 $283K
AlphaCentric Advisors LLC 0.27% New 10,316 $275K
Bleakley Financial Group, LLC 0.01% Add +1.8% 10,080 $269K
Sfmg, LLC 0.02% No change 10,000 $267K
Neo Ivy Capital Management 0.05% New 9,720 $259K
AQR Capital Management 0.00% Add +4.7% 9,366 $250K
BI Asset Management Fondsmaeglerselskab A/S 0.00% New 8,853 $236K
STRS Ohio 0.00% Reduce -12.8% 8,200 $219K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Reduce -3.3% 7,891 $211K
Jain Global LLC 0.01% — 7,850 $210K
Ameritas Investment Partners, Inc. 0.01% Add +6.8% 7,594 $203K
Point72 (DIFC) Ltd 0.02% New 6,889 $184K
KLP Kapitalforvaltning As 0.00% — 6,800 $182K
Quantbot Technologies LP 0.00% New 3,855 $103K
Tower Research Capital LLC (TRC) 0.00% Add +1097.4% 3,676 $98K
Mirae Asset Global Investments Co., Ltd. 0.00% Reduce -7.0% 3,155 $91K
Royal Bank of Canada 0.00% Reduce -62.7% 3,324 $89K
US Bancorp \de 0.00% Reduce -61.2% 3,309 $88K
Meeder Asset Management Inc. 0.01% No change 3,307 $88K
Aquatic Capital Management LLC 0.00% New 2,894 $77K
Public Employees Retirement Association of Colorado 0.00% No change 2,849 $76K
Virtus Advisers, LLC 0.03% Reduce -50.9% 2,526 $67K
Amalgamated Bank 0.00% No change 2,512 $67K
AlphaQuest LLC 0.01% Reduce -75.6% 2,203 $59K
Caitong International Asset Management Co., Ltd 0.05% — 2,053 $55K
Quarry LP 0.01% Reduce -42.9% 2,000 $53K
GF Fund Management Co. LTD. 0.00% — 1,988 $53K
Diadema Partners LP 0.04% — 1,359 $36K
GAMMA Investing LLC 0.00% Add +2.6% 1,321 $35K
Osaic Holdings, Inc. 0.00% Add +18.5% 1,064 $28K
Nisa Investment Advisors, LLC 0.00% Add +6.8% 1,049 $28K
Group One Trading LLC 0.00% New 476 $13K
Signaturefd, LLC 0.00% Reduce -13.2% 466 $12K
Daiwa Securities Group Inc. 0.00% No change 344 $9K
Lindbrook Capital, LLC 0.00% No change 325 $9K
Bfsg, LLC 0.00% Reduce -50.0% 300 $8K
SBI Securities Co., Ltd. 0.00% — 243 $6K
Aster Capital Management (DIFC) Ltd 0.00% New 229 $6K
HighMark Wealth Management LLC 0.00% New 165 $4K
Fortitude Family Office, LLC 0.00% No change 160 $4K
Parallel Advisors, LLC 0.00% Add +2.3% 136 $4K
Comerica Bank 0.00% New 108 $3K
Federated Hermes, Inc. 0.00% Reduce -1.8% 107 $3K
Rothschild Investment LLC 0.00% Add +28.6% 90 $2K
Arax Advisory Partners 0.00% Reduce -23.5% 75 $2K
Sterling Capital Management LLC 0.00% No change 75 $2K
Versant Capital Management, Inc 0.00% No change 40 $1K
Cwm, LLC 0.00% Add +30.0% 26 $1K
Principal Securities, Inc. 0.00% No change 27 $721
Smartleaf Asset Management LLC 0.00% Reduce -72.4% 21 $568
EverSource Wealth Advisors, LLC 0.00% New 18 $480
NewEdge Advisors, LLC 0.00% No change 9 $240
Farther Finance Advisors, LLC 0.00% No change 8 $214
National Bank of Canada 0.00% Add +200.0% 3 $80
Global Retirement Partners, LLC 0.00% Reduce -93.6% 3 $80
Covestor Ltd 0.00% Reduce -28.6% 5 $0

"% of holder's portfolio" is EWTX's weight in each manager's 13F, not the share of Edgewise Therapeutics Inc. the manager owns.