Maze TherapeuticsMAZE
13F holders, Q1 2026 (March 31)165holders +22
45new positions
24sold out
5famous investors
$29.86avg. 13F price*
At the end of Q1 2026, 165 institutions reported holding Maze Therapeutics Inc. (MAZE) in their 13F filings, up 22 from Q4 2025. 45 opened new positions and 24 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($136.3M), TRV GP Iv, LLC ($133.5M) and ARCH Venture Management, LLC ($123.0M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Maze Therapeutics Inc.
- CUSIP
- 578784100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $200.6M |
| Exits | 24 | $97.1M |
All 13F filers, Q4 2025 → Q1 2026: 9,508,203 shares bought and 6,277,782 shares sold, net +3,230,421 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 165 holders
| Frazier Life Sciences Management, L.P. | 3.52% | No change | 4,567,274 | $136.3M |
| TRV GP Iv, LLC | 50.04% | No change | 4,473,958 | $133.5M |
| ARCH Venture Management, LLC | 18.16% | No change | 4,120,053 | $123.0M |
| Deep Track Capital, LP | 2.14% | Reduce -18.1% | 3,477,562 | $103.8M |
| Janus Henderson Group PLC | 0.04% | Reduce -9.0% | 2,858,876 | $85.3M |
| Paradigm Biocapital Advisors LP | 1.67% | New | 2,744,399 | $81.9M |
| BlackRock, Inc. | 0.00% | Add +12.4% | 2,570,425 | $76.7M |
| a16z Capital Management, L.L.C. | 3.94% | No change | 1,702,225 | $50.8M |
| Venrock Adviser, LLC | 1.78% | Add +3.5% | 1,602,034 | $47.8M |
| Vanguard Capital Management LLC | 0.00% | — | 1,435,656 | $42.9M |
| Alphabet Inc. | 1.03% | No change | 1,388,583 | $41.4M |
| Logos Global Management LP | 1.90% | Add +30.0% | 1,235,000 | $36.9M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | New | 1,178,000 | $35.2M |
| General Catalyst Group Management, LLC | 16.85% | No change | 1,035,910 | $30.9M |
| TRV GP V, LLC | 7.08% | No change | 950,800 | $28.4M |
| FMR LLC | 0.00% | Add +18.6% | 864,214 | $25.8M |
| Citadel Advisors | 0.02% | Add +73.1% | 775,714 | $23.2M |
| ArrowMark Colorado Holdings LLC | 0.61% | No change | 767,383 | $22.9M |
| Casdin Capital, LLC | 1.72% | No change | 758,857 | $22.7M |
| Cormorant Asset Management, LP | 1.13% | New | 750,000 | $22.4M |
| Woodline Partners LP | 0.07% | Reduce -37.2% | 650,229 | $19.4M |
| State Street Corp. | 0.00% | Add +19.5% | 636,722 | $19.0M |
| Driehaus Capital Management LLC | 0.14% | Add +68.3% | 636,162 | $19.0M |
| Caligan Partners LP | 1.30% | Add +11.8% | 614,962 | $18.4M |
| Geode Capital Management, LLC | 0.00% | Add +13.8% | 599,967 | $17.9M |
| Bessemer Group Inc. | 0.02% | No change | 481,790 | $14.4M |
| Balyasny Asset Management L.P. | 0.03% | Add +131.5% | 461,151 | $13.8M |
| Ikarian Capital, LLC | 1.62% | Reduce -41.2% | 378,999 | $11.3M |
| Farallon Capital Management, L.L.C. | 0.07% | New | 373,000 | $11.1M |
| HHLR Advisors, LTD. | 0.65% | Reduce -20.0% | 366,028 | $10.9M |
| Marshall Wace, LLP | 0.01% | Reduce -63.4% | 310,639 | $9.3M |
| Boothbay Fund Management, LLC | 0.20% | Reduce -30.5% | 284,476 | $8.5M |
| Washington University | 5.23% | No change | 280,802 | $8.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +144.4% | 279,713 | $8.3M |
| Candriam S.C.A. | 0.04% | New | 278,167 | $8.3M |
| Squadron Capital Management LLC | 3.08% | Reduce -47.5% | 257,500 | $7.7M |
| Mass General Brigham, Inc | 1.53% | No change | 239,994 | $7.2M |
| Freestone Grove Partners LP | 0.05% | Add +97.7% | 234,953 | $7.0M |
| Sphera Funds Management LTD. | 1.17% | Add +216.4% | 227,343 | $6.8M |
| Aberdeen Group plc | 0.01% | New | 226,227 | $6.8M |
| Northern Trust Corp. | 0.00% | Add +19.9% | 211,382 | $6.3M |
| Morgan Stanley | 0.00% | Reduce -20.6% | 204,831 | $6.1M |
| Spruce Street Capital LP | 1.44% | New | 200,000 | $6.0M |
| Vanguard Portfolio Management LLC | 0.00% | — | 195,542 | $5.8M |
| Bank of America Corp. | 0.00% | Add +961.3% | 195,084 | $5.8M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +6.0% | 186,433 | $5.6M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 185,794 | $5.5M |
| Foresite Capital Management IV, LLC | 1.98% | Reduce -70.0% | 156,901 | $4.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 151,000 | $4.5M |
| Holocene Advisors, LP | 0.01% | New | 136,168 | $4.1M |
| Qube Research & Technologies Ltd | 0.01% | New | 134,950 | $4.0M |
| T. Rowe Price Associates Inc. | 0.00% | Add +6.0% | 122,695 | $3.7M |
| Atika Capital Management LLC | 0.53% | New | 111,500 | $3.3M |
| Ameriprise Financial Inc. | 0.00% | Add +11.2% | 107,486 | $3.2M |
| Integral Health Asset Management, LLC | 0.16% | No change | 100,000 | $3.0M |
| Alyeska Investment Group, L.P. | 0.01% | Reduce -49.0% | 100,000 | $3.0M |
| HighVista Strategies LLC | 0.82% | Reduce -41.4% | 99,850 | $3.0M |
| UBS Group AG | 0.00% | Add +227.2% | 93,898 | $2.8M |
| Alliancebernstein L.P. | 0.00% | Add +95.0% | 64,762 | $2.7M |
| Exome Asset Management LLC | 1.55% | New | 88,510 | $2.6M |
| Invesco Ltd. | 0.00% | Reduce -35.5% | 86,419 | $2.6M |
| SummitTX Capital, L.P. | 0.08% | Add +20.4% | 83,750 | $2.5M |
| Bank of New York Mellon Corp | 0.00% | Add +22.9% | 74,268 | $2.2M |
| Raymond James Financial Inc. | 0.00% | Add +2.5% | 69,375 | $2.1M |
| Nuveen, LLC | 0.00% | Add +10.7% | 63,360 | $1.9M |
| Wellington Management Group LLP | 0.00% | Reduce -1.0% | 60,587 | $1.8M |
| Osaic Holdings, Inc. | 0.00% | Add +0.3% | 59,943 | $1.8M |
| Franklin Resources Inc. | 0.00% | Add +8.0% | 59,637 | $1.8M |
| JPMorgan Chase & Co. | 0.00% | Add +192.1% | 58,446 | $1.7M |
| ADAR1 Capital Management, LLC | 0.09% | Reduce -72.1% | 50,095 | $1.5M |
| D. E. Shaw & Co. | 0.00% | Add +35.4% | 45,636 | $1.4M |
| Propel Bio Management, LLC | 0.82% | New | 43,798 | $1.3M |
| Alps Advisors Inc. | 0.01% | New | 39,171 | $1.2M |
| Schroder Investment Management Group | 0.00% | New | 37,181 | $1.1M |
| DAFNA Capital Management LLC | 0.24% | New | 35,000 | $1.0M |
| Aquatic Capital Management LLC | 0.03% | New | 34,977 | $1.0M |
| Russell Investments Group, Ltd. | 0.00% | Add +44.3% | 32,526 | $971K |
| Parkman Healthcare Partners LLC | 0.10% | Reduce -84.8% | 31,844 | $951K |
| Rhumbline Advisers | 0.00% | Add +32.8% | 31,513 | $941K |
| Twinbeech Capital LP | 0.10% | New | 30,989 | $925K |
| Seven Fleet Capital Management LP | 0.29% | New | 30,707 | $917K |
| Millennium Management | 0.00% | Reduce -80.7% | 29,892 | $892K |
| Walleye Capital LLC | 0.01% | New | 27,945 | $834K |
| AQR Capital Management | 0.00% | Add +1.8% | 27,945 | $834K |
| XTX Topco Ltd | 0.01% | Reduce -18.7% | 26,854 | $802K |
| Foresite Capital Management V, LLC | 0.29% | Reduce -70.0% | 25,905 | $773K |
| First Trust Advisors LP | 0.00% | New | 25,485 | $761K |
| Susquehanna International Group, LLP | 0.00% | New | 25,301 | $755K |
| Blackstone Inc. | 0.00% | New | 24,990 | $746K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 21,728 | $649K |
| Deutsche Bank AG | 0.00% | Add +30.5% | 20,263 | $605K |
| Acuta Capital Partners, LLC | 0.41% | Reduce -3.3% | 19,335 | $577K |
| Verition Fund Management LLC | 0.01% | Reduce -15.0% | 19,134 | $571K |
| Prelude Capital Management, LLC | 0.04% | New | 18,127 | $541K |
| Caitong International Asset Management Co., Ltd | 0.10% | Add +407.9% | 17,783 | $531K |
| Gilder Gagnon Howe & Co. LLC | 0.01% | Reduce -24.9% | 17,487 | $522K |
| Two Sigma Investments, LP | 0.00% | Add +118.7% | 15,845 | $473K |
| Renaissance Technologies | 0.00% | Reduce -41.7% | 15,800 | $472K |
| Vanguard Global Advisers, LLC | 0.00% | — | 15,202 | $454K |
| Engineers Gate Manager LP | 0.01% | New | 15,110 | $451K |
"% of holder's portfolio" is MAZE's weight in each manager's 13F, not the share of Maze Therapeutics Inc. the manager owns.