Maze TherapeuticsMAZE
13F holders, Q2 2026 (June 30)At the end of Q2 2026, 161 institutions reported holding Maze Therapeutics Inc. (MAZE) in their 13F filings, down 4 from Q1 2026. 36 opened new positions and 39 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($150.2M), TRV GP Iv, LLC ($133.5M) and ARCH Venture Management, LLC ($123.0M). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Maze Therapeutics Inc.
- CUSIP
- 578784100
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 36 | $140.4M |
| Exits | 39 | $169.7M |
All 13F filers, Q1 2026 → Q2 2026: 13,821,210 shares bought and 7,511,283 shares sold, net +6,309,927 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 161 holders
| Frazier Life Sciences Management, L.P. | 3.28% | Add +10.2% | 5,032,915 | $150.2M |
| TRV GP Iv, LLC | 52.63% | No change | 4,473,958 | $133.5M |
| ARCH Venture Management, LLC | 11.18% | No change | 4,120,053 | $123.0M |
| Deep Track Capital, LP | 1.64% | Add +7.3% | 3,732,569 | $111.4M |
| BlackRock, Inc. | 0.00% | Add +36.3% | 3,502,841 | $104.5M |
| Jupiter Topco LLC | 0.04% | — | 3,408,045 | $101.8M |
| T. Rowe Price Investment Management, Inc. | 0.05% | New | 2,603,682 | $77.7M |
| Logos Global Management LP | 2.49% | Add +56.7% | 1,935,000 | $57.7M |
| Vanguard Capital Management LLC | 0.00% | Add +23.9% | 1,778,222 | $53.1M |
| a16z Capital Management, L.L.C. | 0.36% | No change | 1,702,225 | $50.8M |
| Venrock Adviser, LLC | 1.45% | No change | 1,602,034 | $47.8M |
| Alphabet Inc. | 0.04% | No change | 1,388,583 | $41.4M |
| Braidwell LP | 1.31% | New | 1,140,040 | $34.0M |
| Farallon Capital Management, L.L.C. | 0.20% | Add +197.0% | 1,107,814 | $33.1M |
| FMR LLC | 0.00% | Add +22.3% | 1,056,959 | $31.5M |
| General Catalyst Group Management, LLC | 16.40% | No change | 1,035,910 | $30.9M |
| State Street Corp. | 0.00% | Add +56.7% | 997,533 | $29.8M |
| Driehaus Capital Management LLC | 0.17% | Add +50.1% | 954,886 | $28.5M |
| TRV GP V, LLC | 5.69% | No change | 950,800 | $28.4M |
| JPMorgan Chase & Co. | 0.00% | Add +1549.4% | 964,011 | $28.0M |
| Marshall Wace, LLP | 0.02% | Add +194.4% | 914,572 | $27.3M |
| Geode Capital Management, LLC | 0.00% | Add +43.0% | 858,054 | $25.6M |
| Citadel Advisors | 0.01% | Add +9.9% | 852,676 | $25.4M |
| Casdin Capital, LLC | 1.26% | Add +11.2% | 843,857 | $25.2M |
| ArrowMark Colorado Holdings LLC | 0.96% | No change | 767,383 | $22.9M |
| Woodline Partners LP | 0.07% | Add +13.2% | 736,216 | $22.0M |
| Bessemer Group Inc. | 0.02% | No change | 481,790 | $14.4M |
| Sphera Funds Management LTD. | 1.78% | Add +83.7% | 417,564 | $12.5M |
| Vanguard Portfolio Management LLC | 0.00% | Add +101.0% | 393,107 | $11.7M |
| Aberdeen Group plc | 0.02% | Add +69.6% | 383,773 | $11.5M |
| Ikarian Capital, LLC | 1.85% | No change | 378,999 | $11.3M |
| HHLR Advisors, LTD. | 1.31% | No change | 366,028 | $10.9M |
| ADAR1 Capital Management, LLC | 0.48% | Add +577.3% | 339,276 | $10.1M |
| Squadron Capital Management LLC | 3.42% | Add +30.1% | 335,000 | $10.0M |
| Bank of America Corp. | 0.00% | Add +64.7% | 321,227 | $9.6M |
| Northern Trust Corp. | 0.00% | Add +39.4% | 294,742 | $8.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +4.8% | 293,144 | $8.7M |
| Candriam S.C.A. | 0.04% | Reduce -1.5% | 273,932 | $8.2M |
| Hudson Bay Capital Management LP | 0.04% | Add +3212.9% | 270,000 | $8.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +39.8% | 260,566 | $7.8M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | Reduce -79.0% | 248,000 | $7.4M |
| Mass General Brigham, Inc | 1.98% | No change | 239,994 | $7.2M |
| Ameriprise Financial Inc. | 0.00% | Add +111.6% | 227,425 | $6.8M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +45.6% | 219,938 | $6.6M |
| RTW Investments, LP | 0.05% | New | 212,000 | $6.3M |
| Schroder Investment Management Group | 0.00% | Add +437.6% | 199,872 | $5.8M |
| Two Sigma Investments, LP | 0.00% | Add +1117.8% | 192,952 | $5.8M |
| Boothbay Fund Management, LLC | 0.11% | Reduce -33.6% | 188,857 | $5.6M |
| ExodusPoint Capital Management, LP | 0.05% | New | 183,264 | $5.5M |
| SummitTX Capital, L.P. | 0.14% | Add +110.5% | 176,291 | $5.3M |
| HighVista Strategies LLC | 0.93% | Add +36.8% | 136,572 | $4.1M |
| Morgan Stanley | 0.00% | Reduce -34.0% | 135,168 | $4.0M |
| T. Rowe Price Associates Inc. | 0.00% | Add +8.3% | 132,870 | $4.0M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -2.9% | 131,043 | $3.9M |
| Walleye Capital LLC | 0.02% | Add +358.1% | 128,006 | $3.8M |
| Exome Asset Management LLC | 2.11% | Add +29.6% | 114,692 | $3.4M |
| Ensign Peak Advisors, Inc | 0.01% | Reduce -45.3% | 101,644 | $3.0M |
| Alyeska Investment Group, L.P. | 0.01% | No change | 100,000 | $3.0M |
| Bank of New York Mellon Corp | 0.00% | Add +31.4% | 97,588 | $2.9M |
| Algert Global LLC | 0.03% | New | 93,357 | $2.8M |
| UBS Group AG | 0.00% | Reduce -9.8% | 84,679 | $2.5M |
| Wellington Management Group LLP | 0.00% | Add +36.5% | 82,724 | $2.5M |
| Trexquant Investment LP | 0.02% | New | 81,668 | $2.4M |
| Franklin Resources Inc. | 0.00% | Add +34.5% | 80,216 | $2.4M |
| Nuveen, LLC | 0.00% | Add +23.8% | 78,468 | $2.3M |
| Osaic Holdings, Inc. | 0.00% | Add +29.9% | 77,850 | $2.3M |
| BNP Paribas Financial Markets | 0.00% | Add +1093.1% | 77,251 | $2.3M |
| XTX Topco Ltd | 0.03% | Add +180.5% | 75,317 | $2.2M |
| Los Angeles Capital Management LLC | 0.01% | Add +689.6% | 74,384 | $2.2M |
| Raymond James Financial Inc. | 0.00% | Reduce -4.4% | 66,353 | $2.0M |
| Jacobs Levy Equity Management, Inc. | 0.01% | New | 65,468 | $2.0M |
| DAFNA Capital Management LLC | 0.37% | Add +85.7% | 65,000 | $1.9M |
| Alps Advisors Inc. | 0.01% | Add +42.9% | 55,970 | $1.7M |
| Jump Financial, LLC | 0.01% | New | 47,129 | $1.4M |
| Swiss National Bank | 0.00% | New | 47,100 | $1.4M |
| First Trust Advisors LP | 0.00% | Add +81.4% | 46,227 | $1.4M |
| Propel Bio Management, LLC | 0.68% | No change | 43,798 | $1.3M |
| Rhumbline Advisers | 0.00% | Add +36.0% | 42,873 | $1.3M |
| Alliancebernstein L.P. | 0.00% | Reduce -41.6% | 37,800 | $1.1M |
| Deutsche Bank AG | 0.00% | Add +72.7% | 34,993 | $1.0M |
| Wells Fargo & Company | 0.00% | Add +209.1% | 32,047 | $956K |
| Citigroup Inc. | 0.00% | Add +253.4% | 30,265 | $903K |
| Quadrature Capital Ltd | 0.01% | New | 30,047 | $897K |
| Invesco Ltd. | 0.00% | Reduce -67.2% | 28,372 | $847K |
| AQR Capital Management | 0.00% | Reduce -2.8% | 27,161 | $810K |
| California State Teachers Retirement System | 0.00% | Add +1716.2% | 26,063 | $778K |
| State of Wisconsin Investment Board | 0.00% | New | 23,840 | $711K |
| Barclays PLC | 0.00% | Add +156.2% | 23,733 | $708K |
| Susquehanna International Group, LLP | 0.00% | Reduce -6.4% | 23,677 | $707K |
| TD Asset Management Inc | 0.00% | New | 22,174 | $662K |
| MetLife Investment Management, LLC | 0.00% | Add +43.7% | 20,899 | $624K |
| Balyasny Asset Management L.P. | 0.00% | Reduce -95.6% | 20,190 | $602K |
| Squarepoint Ops LLC | 0.00% | Add +42.8% | 19,434 | $580K |
| Verition Fund Management LLC | 0.00% | Reduce -4.9% | 18,201 | $543K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +4054.3% | 17,739 | $529K |
| Jackson Creek Investment Advisors LLC | 0.16% | New | 18,345 | $494K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | New | 16,436 | $490K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +12.6% | 16,402 | $489K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +30.9% | 16,248 | $485K |
| Legal & General Group Plc | 0.00% | Add +172.6% | 15,781 | $471K |
| Axq Capital, LP | 0.05% | Add +114.1% | 15,193 | $453K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -55.4% | 14,508 | $433K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | Reduce -33.9% | 14,370 | $429K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +15.1% | 13,808 | $412K |
| Virtus Investment Advisers, LLC | 0.09% | Add +93.9% | 13,605 | $406K |
| Verdad Advisers, LP | 0.36% | New | 12,618 | $377K |
| New York State Common Retirement Fund | 0.00% | Add +51.2% | 12,400 | $370K |
| Jain Global LLC | 0.00% | New | 12,238 | $365K |
| D. E. Shaw & Co. | 0.00% | Reduce -73.7% | 12,019 | $359K |
| Entropy Technologies, LP | 0.01% | New | 11,327 | $338K |
| Engineers Gate Manager LP | 0.00% | Reduce -26.3% | 11,143 | $333K |
| Vanguard Global Advisers, LLC | 0.00% | Reduce -27.3% | 11,055 | $330K |
| Profund Advisors LLC | 0.01% | New | 11,025 | $329K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +46.6% | 10,407 | $311K |
| EntryPoint Capital, LLC | 0.07% | New | 9,814 | $293K |
| Falcon Wealth Planning | 0.02% | Reduce -0.1% | 9,630 | $287K |
| Canada Pension Plan Investment Board | 0.00% | New | 9,100 | $272K |
| Intech Investment Management LLC | 0.00% | Reduce -9.8% | 8,594 | $256K |
| Rafferty Asset Management, LLC | 0.00% | New | 8,077 | $241K |
| Creative Planning | 0.00% | New | 8,072 | $241K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 7,592 | $227K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.07% | New | 7,465 | $223K |
| Voya Investment Management LLC | 0.00% | New | 6,975 | $208K |
| Persistent Asset Partners Ltd | 0.06% | Reduce -23.5% | 6,709 | $200K |
| Vanguard Investments Australia, Ltd. | 0.00% | New | 5,848 | $175K |
| KLP Kapitalforvaltning As | 0.00% | New | 5,300 | $158K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +47.9% | 3,202 | $96K |
| Caitong International Asset Management Co., Ltd | 0.01% | Reduce -82.4% | 3,131 | $93K |
| Quantbot Technologies LP | 0.00% | New | 2,672 | $80K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Reduce -1.4% | 2,475 | $74K |
| Group One Trading LLC | 0.00% | New | 2,052 | $61K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | New | 1,600 | $48K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -51.1% | 1,357 | $40K |
| Simplex Trading, LLC | 0.00% | Reduce -3.6% | 1,166 | $35K |
| Royal Bank of Canada | 0.00% | Reduce -47.2% | 1,072 | $32K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -5.5% | 1,021 | $30K |
| State of Wyoming | 0.00% | New | 813 | $24K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +81.4% | 655 | $20K |
| IFP Advisors, Inc | 0.00% | Reduce -96.3% | 328 | $10K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -9.2% | 326 | $10K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -80.1% | 279 | $8K |
| Sterling Capital Management LLC | 0.00% | Reduce -73.2% | 222 | $7K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 221 | $7K |
| GAMMA Investing LLC | 0.00% | Reduce -51.7% | 170 | $5K |
| Quarry LP | 0.00% | New | 165 | $5K |
| Arax Advisory Partners | 0.00% | New | 154 | $5K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -26.6% | 149 | $4K |
| Torren Management, LLC | 0.00% | No change | 112 | $3K |
| Jones Financial Companies LLLP | 0.00% | No change | 90 | $3K |
| US Bancorp \de | 0.00% | Add +788.9% | 80 | $2K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 50 | $1K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -44.8% | 32 | $955 |
| Cornerstone Financial Management LLC | 0.00% | No change | 28 | $836 |
| Signaturefd, LLC | 0.00% | Reduce -89.9% | 17 | $507 |
| Fortitude Family Office, LLC | 0.00% | New | 11 | $328 |
| Essential Partners LLC | 0.00% | No change | 7 | $209 |
| SBI Securities Co., Ltd. | 0.00% | No change | 6 | $179 |
| Rothschild Investment LLC | 0.00% | Reduce -75.0% | 5 | $149 |
| Allworth Financial LP | 0.00% | Reduce -85.7% | 2 | $60 |
| Global Retirement Partners, LLC | 0.00% | — | 1 | $30 |
| Covestor Ltd | 0.00% | Add +300.0% | 12 | $0 |
"% of holder's portfolio" is MAZE's weight in each manager's 13F, not the share of Maze Therapeutics Inc. the manager owns.