MBX BiosciencesMBX
13F holders, Q3 2025 (September 30)118holders +30
39new positions
9sold out
4famous investors
$17.50avg. 13F price*
At the end of Q3 2025, 118 institutions reported holding MBX Biosciences Inc. (MBX) in their 13F filings, up 30 from Q2 2025. 39 opened new positions and 9 sold out. The largest holders were Frazier Life Sciences Management, L.P. ($116.4M), Wellington Management Group LLP ($84.4M) and Orbimed Advisors LLC ($70.1M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- MBX Biosciences Inc.
- CUSIP
- 55287L101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $103.5M |
| Exits | 9 | $23.1M |
All 13F filers, Q2 2025 → Q3 2025: 14,670,364 shares bought and 3,719,664 shares sold, net +10,950,700 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 118 holders
| Frazier Life Sciences Management, L.P. | 3.50% | Add +11.1% | 6,652,013 | $116.4M |
| Wellington Management Group LLP | 0.01% | Add +112.8% | 4,823,336 | $84.4M |
| Orbimed Advisors LLC | 1.68% | No change | 4,002,887 | $70.1M |
| NEA Management Company, LLC | 3.47% | No change | 3,614,486 | $63.3M |
| Deep Track Capital, LP | 1.54% | Add +43.9% | 3,150,000 | $55.1M |
| NVP Associates, LLC | 22.51% | No change | 2,136,335 | $37.4M |
| EcoR1 Capital, LLC | 1.79% | Add +84.7% | 2,123,604 | $37.2M |
| Kynam Capital Management, LP | 2.61% | New | 2,000,000 | $35.0M |
| BlackRock, Inc. | 0.00% | Add +93.5% | 1,957,461 | $34.3M |
| Vanguard Group Inc. | 0.00% | Add +60.7% | 1,677,362 | $29.4M |
| Driehaus Capital Management LLC | 0.19% | Reduce -2.0% | 1,539,639 | $26.9M |
| Franklin Resources Inc. | 0.01% | Add +164.2% | 1,307,288 | $22.9M |
| Cormorant Asset Management, LP | 1.48% | Add +75.0% | 1,225,000 | $21.4M |
| Woodline Partners LP | 0.10% | Add +33.3% | 1,201,150 | $21.0M |
| Citadel Advisors | 0.01% | New | 996,083 | $17.4M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -29.1% | 954,726 | $16.7M |
| Parkman Healthcare Partners LLC | 1.49% | Reduce -11.3% | 773,304 | $13.5M |
| Millennium Management | 0.01% | Reduce -14.5% | 655,416 | $11.5M |
| TCG Crossover Management, LLC | 0.56% | No change | 650,000 | $11.4M |
| Point72 Asset Management | 0.03% | Reduce -35.5% | 627,667 | $11.0M |
| Geode Capital Management, LLC | 0.00% | Add +36.0% | 473,932 | $8.3M |
| Goldman Sachs Group Inc. | 0.00% | New | 358,121 | $6.3M |
| State Street Corp. | 0.00% | Add +20.4% | 319,274 | $5.6M |
| Schonfeld Strategic Advisors LLC | 0.03% | Reduce -55.2% | 282,677 | $4.9M |
| Rock Springs Capital Management LP | 0.29% | New | 282,624 | $4.9M |
| Baker Bros. Advisors LP | 0.04% | New | 277,777 | $4.9M |
| Soleus Capital Management, L.P. | 0.26% | New | 275,000 | $4.8M |
| Opaleye Management Inc. | 0.63% | Add +5.7% | 253,000 | $4.4M |
| Longaeva Partners L.P. | 0.85% | New | 224,433 | $3.9M |
| PFM Health Sciences, LP | 0.34% | New | 221,505 | $3.9M |
| Sectoral Asset Management Inc. | 2.11% | Add +1.6% | 194,898 | $3.4M |
| Tetragon Partners GP Ltd | 0.75% | New | 177,840 | $3.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +58.2% | 170,006 | $3.0M |
| Affinity Asset Advisors, LLC | 0.28% | New | 165,000 | $2.9M |
| Northern Trust Corp. | 0.00% | Add +15.3% | 133,265 | $2.3M |
| TD Asset Management Inc | 0.00% | Reduce -30.6% | 118,792 | $2.1M |
| Burkehill Global Management, LP | 0.10% | New | 100,000 | $1.8M |
| ExodusPoint Capital Management, LP | 0.02% | New | 100,000 | $1.8M |
| Schroder Investment Management Group | 0.00% | New | 83,766 | $1.5M |
| DAFNA Capital Management LLC | 0.37% | New | 85,000 | $1.5M |
| Hudson Bay Capital Management LP | 0.01% | New | 85,000 | $1.5M |
| Murchinson Ltd. | 0.28% | New | 80,000 | $1.4M |
| Stempoint Capital LP | 0.26% | Reduce -46.8% | 75,000 | $1.3M |
| Platinum Investment Management Ltd. | 0.08% | Reduce -38.4% | 69,428 | $1.2M |
| FMR LLC | 0.00% | Add +12.5% | 68,976 | $1.2M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -21.5% | 68,376 | $1.2M |
| UBS Group AG | 0.00% | Add +96.1% | 60,725 | $1.1M |
| Exome Asset Management LLC | 0.61% | Reduce -16.9% | 52,402 | $917K |
| Aaron Wealth Advisors LLC | 0.05% | No change | 50,000 | $875K |
| Ikarian Capital, LLC | 0.17% | New | 48,071 | $841K |
| Bank of New York Mellon Corp | 0.00% | Add +25.5% | 47,735 | $835K |
| Morgan Stanley | 0.00% | Add +86.9% | 44,868 | $785K |
| Boothbay Fund Management, LLC | 0.02% | New | 39,498 | $691K |
| Readystate Asset Management LP | 0.07% | New | 38,500 | $674K |
| XTX Topco Ltd | 0.03% | Add +223.6% | 38,378 | $672K |
| Ghisallo Capital Management LLC | 0.02% | New | 38,250 | $669K |
| Weiss Asset Management LP | 0.01% | New | 30,823 | $539K |
| SummitTX Capital, L.P. | 0.02% | New | 29,310 | $513K |
| Creative Planning | 0.00% | New | 28,732 | $503K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | New | 28,461 | $498K |
| Koa Wealth Management, LLC | 0.35% | Reduce -15.9% | 26,713 | $467K |
| Bank of America Corp. | 0.00% | Reduce -37.2% | 26,616 | $466K |
| Balyasny Asset Management L.P. | 0.00% | New | 25,641 | $449K |
| Nuveen, LLC | 0.00% | No change | 22,143 | $388K |
| Rhumbline Advisers | 0.00% | Reduce -7.8% | 21,821 | $382K |
| Barclays PLC | 0.00% | Reduce -63.1% | 21,626 | $378K |
| Caption Management, LLC | 0.02% | New | 20,000 | $350K |
| Alps Advisors Inc. | 0.00% | Reduce -6.7% | 16,840 | $295K |
| AQR Capital Management | 0.00% | Reduce -12.4% | 15,764 | $276K |
| Walleye Capital LLC | 0.00% | Reduce -78.4% | 15,176 | $266K |
| Silverarc Capital Management, LLC | 0.04% | New | 15,000 | $263K |
| Bridgeway Capital Management, LLC | 0.01% | Reduce -51.4% | 14,200 | $249K |
| Two Sigma Investments, LP | 0.00% | New | 13,587 | $238K |
| Invesco Ltd. | 0.00% | New | 11,788 | $206K |
| Wells Fargo & Company | 0.00% | Add +7.4% | 11,755 | $206K |
| MetLife Investment Management, LLC | 0.00% | No change | 11,018 | $193K |
| Deutsche Bank AG | 0.00% | Add +24.7% | 10,923 | $191K |
| Virtus Investment Advisers, LLC | 0.05% | Add +21.0% | 10,614 | $186K |
| Alliancebernstein L.P. | 0.00% | No change | 10,500 | $184K |
| Man Group plc | 0.00% | New | 10,225 | $179K |
| Symmetry Investments LP | 0.01% | New | 10,000 | $175K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -23.7% | 7,120 | $125K |
| Quarry LP | 0.03% | Reduce -18.8% | 6,499 | $114K |
| JPMorgan Chase & Co. | 0.00% | Reduce -24.6% | 6,175 | $108K |
| China Universal Asset Management Co., Ltd. | 0.01% | New | 5,000 | $88K |
| Acadian Asset Management LLC | 0.00% | New | 5,009 | $86K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +110.4% | 4,509 | $79K |
| New York State Common Retirement Fund | 0.00% | No change | 4,300 | $75K |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -91.2% | 3,000 | $53K |
| BNP Paribas Financial Markets | 0.00% | Add +117.9% | 2,896 | $51K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 1,592 | $28K |
| FNY Investment Advisers, LLC | 0.01% | New | 1,575 | $27K |
| Russell Investments Group, Ltd. | 0.00% | Add +4131.4% | 1,481 | $26K |
| Cwm, LLC | 0.00% | Reduce -23.2% | 1,384 | $24K |
| Legal & General Group Plc | 0.00% | Reduce -14.4% | 1,328 | $23K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -40.0% | 1,267 | $22K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,177 | $21K |
| California State Teachers Retirement System | 0.00% | Add +0.1% | 1,065 | $19K |
| Sterling Capital Management LLC | 0.00% | Add +130.0% | 1,058 | $19K |
| Royal Bank of Canada | 0.00% | Reduce -26.0% | 960 | $17K |
| STRS Ohio | 0.00% | No change | 700 | $12K |
| Amalgamated Bank | 0.00% | No change | 384 | $7K |
| Arax Advisory Partners | 0.00% | New | 398 | $7K |
| US Bancorp \de | 0.00% | No change | 337 | $6K |
| Farther Finance Advisors, LLC | 0.00% | New | 328 | $6K |
| GAMMA Investing LLC | 0.00% | No change | 299 | $5K |
| PNC Financial Services Group, Inc. | 0.00% | New | 252 | $4K |
| Signaturefd, LLC | 0.00% | Add +77.2% | 179 | $3K |
| Citigroup Inc. | 0.00% | Reduce -96.9% | 178 | $3K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 109 | $2K |
| Washington Trust Advisors, Inc. | 0.00% | New | 83 | $1K |
| Comerica Bank | 0.00% | New | 76 | $1K |
| Rise Advisors, LLC | 0.00% | No change | 68 | $1K |
| Parallel Advisors, LLC | 0.00% | Reduce -43.5% | 61 | $1K |
| Allworth Financial LP | 0.00% | No change | 25 | $438 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -20.7% | 23 | $403 |
| Rothschild Investment LLC | 0.00% | No change | 20 | $350 |
| Essential Partners LLC | 0.00% | No change | 2 | $35 |
"% of holder's portfolio" is MBX's weight in each manager's 13F, not the share of MBX Biosciences Inc. the manager owns.