Madrigal PharmaceuticalsMDGL
13F holders, Q3 2025 (September 30)352holders +47
84new positions
35sold out
10famous investors
$458.48avg. 13F price*
At the end of Q3 2025, 352 institutions reported holding Madrigal Pharmaceuticals Inc. (MDGL) in their 13F filings, up 47 from Q2 2025. 84 opened new positions and 35 sold out. The largest holders were Baker Bros. Advisors LP ($982.3M), RTW Investments, LP ($914.4M) and Paulson & Co. ($874.9M). 10 famous investors held it, including John Paulson (29.5% of Paulson & Co.'s portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Ray Dalio (0.0% of Bridgewater Associates's portfolio).
- Company
- Madrigal Pharmaceuticals Inc.
- CUSIP
- 558868105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 84 | $328.6M |
| Exits | 35 | $63.2M |
All 13F filers, Q2 2025 → Q3 2025: 2,487,480 shares bought and 2,487,519 shares sold, net −39 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 352 holders
| Baker Bros. Advisors LP | 7.12% | Add +8.4% | 2,141,701 | $982.3M |
| RTW Investments, LP | 11.27% | No change | 1,993,687 | $914.4M |
| Paulson & Co. | 29.46% | Reduce -8.7% | 1,907,523 | $874.9M |
| Janus Henderson Group PLC | 0.39% | Reduce -15.9% | 1,842,690 | $845.3M |
| Avoro Capital Advisors LLC | 10.88% | Reduce -2.2% | 1,833,000 | $840.7M |
| Vanguard Group Inc. | 0.01% | Reduce -3.5% | 1,812,054 | $831.1M |
| BlackRock, Inc. | 0.01% | Add +8.4% | 1,559,712 | $715.4M |
| State Street Corp. | 0.01% | Reduce -4.7% | 658,097 | $301.8M |
| Geode Capital Management, LLC | 0.01% | Add +7.7% | 446,233 | $204.7M |
| William Blair Investment Management, LLC | 0.49% | Add +17.6% | 411,802 | $188.9M |
| Wellington Management Group LLP | 0.03% | Add +5381.2% | 404,455 | $185.5M |
| FMR LLC | 0.01% | Reduce -9.9% | 401,136 | $184.0M |
| Goldman Sachs Group Inc. | 0.03% | Add +103.4% | 386,100 | $177.1M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -30.7% | 352,520 | $161.7M |
| Invesco Ltd. | 0.02% | Add +49.5% | 299,565 | $137.4M |
| Polar Capital Holdings Plc | 0.59% | Add +17.6% | 265,154 | $121.6M |
| Morgan Stanley | 0.01% | Add +0.7% | 249,647 | $114.5M |
| Bank of America Corp. | 0.01% | Reduce -11.9% | 244,292 | $112.0M |
| Hood River Capital Management LLC | 1.31% | Reduce -0.8% | 242,808 | $111.4M |
| UBS Group AG | 0.02% | Reduce -57.0% | 217,343 | $99.7M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +39.6% | 213,652 | $98.0M |
| Artisan Partners Limited Partnership | 0.14% | Add +2.3% | 206,254 | $94.6M |
| Erste Asset Management GmbH | 0.86% | No change | 201,100 | $89.1M |
| Pictet Asset Management Holding SA | 0.08% | Reduce -7.9% | 191,796 | $87.7M |
| American Century Companies Inc. | 0.04% | Reduce -1.3% | 165,615 | $76.0M |
| Northern Trust Corp. | 0.01% | Add +12.0% | 159,988 | $73.4M |
| Rock Springs Capital Management LP | 3.71% | Reduce -1.8% | 137,746 | $63.2M |
| Fiera Capital Corp | 0.19% | Reduce -2.2% | 127,800 | $58.6M |
| ArrowMark Colorado Holdings LLC | 1.05% | Reduce -14.9% | 123,259 | $56.5M |
| Renaissance Technologies | 0.07% | Add +1013.7% | 120,682 | $55.4M |
| Alkeon Capital Management LLC | 0.25% | New | 120,000 | $55.0M |
| Armistice Capital, LLC | 1.73% | Reduce -3.2% | 119,982 | $55.0M |
| Driehaus Capital Management LLC | 0.38% | New | 115,974 | $53.2M |
| Affinity Asset Advisors, LLC | 5.06% | Add +43.8% | 115,000 | $52.7M |
| Susquehanna International Group, LLP | 0.07% | Add +4.5% | 104,818 | $48.1M |
| Woodline Partners LP | 0.22% | Reduce -34.9% | 103,847 | $47.6M |
| Lord, Abbett & Co. LLC | 0.15% | Add +21.3% | 102,143 | $46.8M |
| MPM Bioimpact LLC | 7.54% | No change | 100,415 | $46.1M |
| Bank of New York Mellon Corp | 0.01% | Add +9.9% | 97,779 | $44.8M |
| D. E. Shaw & Co. | 0.04% | Reduce -14.1% | 96,182 | $44.1M |
| Jane Street Group, LLC | 0.05% | New | 95,734 | $43.9M |
| Adage Capital Partners Gp, L.L.C. | 0.06% | Reduce -76.5% | 88,500 | $40.6M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.12% | Reduce -14.3% | 85,773 | $39.3M |
| Balyasny Asset Management L.P. | 0.08% | Add +138.8% | 82,401 | $37.8M |
| Franklin Resources Inc. | 0.01% | Add +24.5% | 75,570 | $34.7M |
| EcoR1 Capital, LLC | 1.65% | No change | 75,000 | $34.4M |
| Nuveen, LLC | 0.01% | Add +77.5% | 73,715 | $33.8M |
| BNP Paribas Financial Markets | 0.03% | Add +2.5% | 70,757 | $32.5M |
| Raymond James Financial Inc. | 0.01% | Add +28.5% | 70,584 | $32.4M |
| New York State Common Retirement Fund | 0.04% | Add +13.4% | 69,273 | $31.8M |
| Soleus Capital Management, L.P. | 1.68% | Add +754.2% | 68,336 | $31.3M |
| Tri Locum Partners LP | 7.14% | Reduce -30.8% | 67,706 | $31.1M |
| Voya Investment Management LLC | 0.03% | Add +16.3% | 59,437 | $27.3M |
| Iron Triangle Partners LP | 3.81% | New | 58,378 | $26.8M |
| Ensign Peak Advisors, Inc | 0.04% | Add +10.1% | 53,267 | $24.4M |
| EULAV Asset Management | 0.54% | Add +64.5% | 51,000 | $23.4M |
| Emerald Advisers, LLC | 0.75% | Reduce -4.5% | 50,737 | $23.3M |
| Mirae Asset Global Investments Co., Ltd. | 0.07% | Reduce -28.3% | 50,578 | $23.2M |
| Candriam S.C.A. | 0.12% | No change | 49,965 | $22.9M |
| Barclays PLC | 0.01% | Reduce -20.4% | 49,912 | $22.9M |
| Citadel Advisors | 0.02% | Reduce -76.7% | 48,372 | $22.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -14.4% | 47,824 | $21.9M |
| Russell Investments Group, Ltd. | 0.02% | Add +32.0% | 44,885 | $20.6M |
| Rheos Capital Works Inc. | 1.11% | No change | 43,215 | $19.8M |
| Point72 Asset Management | 0.04% | Reduce -62.8% | 41,233 | $18.9M |
| Tao Capital Management LP | 14.22% | Reduce -63.6% | 41,000 | $18.8M |
| Wells Fargo & Company | 0.00% | Add +3.1% | 37,818 | $17.3M |
| Deutsche Bank AG | 0.01% | Add +54.9% | 37,342 | $17.1M |
| Alliancebernstein L.P. | 0.01% | Add +68.0% | 35,695 | $16.4M |
| Emerald Mutual Fund Advisers Trust | 0.83% | Reduce -5.0% | 35,091 | $16.1M |
| Ally Bridge Group (NY) LLC | 12.54% | New | 32,662 | $15.0M |
| Gilder Gagnon Howe & Co. LLC | 0.14% | Reduce -2.2% | 30,848 | $14.1M |
| Squarepoint Ops LLC | 0.03% | Add +583.2% | 29,936 | $13.7M |
| Steadfast Capital Management LP | 0.25% | New | 29,800 | $13.7M |
| Swiss National Bank | 0.01% | Add +1.8% | 27,900 | $12.8M |
| Bridgewater Associates | 0.05% | New | 27,785 | $12.7M |
| Groupama Asset Managment | 0.19% | Reduce -32.9% | 27,444 | $12.6M |
| Rhumbline Advisers | 0.01% | Add +3.4% | 27,263 | $12.5M |
| California Public Employees Retirement System | 0.01% | Reduce -12.6% | 24,097 | $11.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -41.0% | 23,476 | $10.8M |
| LPL Financial LLC | 0.00% | Add +59.6% | 22,538 | $10.3M |
| Segall Bryant & Hamill, LLC | 0.14% | New | 22,490 | $10.3M |
| Legal & General Group Plc | 0.00% | Reduce -6.2% | 21,671 | $9.9M |
| Man Group plc | 0.02% | Add +1460.2% | 21,328 | $9.8M |
| Jump Financial, LLC | 0.13% | New | 20,956 | $9.6M |
| Royal Bank of Canada | 0.00% | Add +110.1% | 20,173 | $9.3M |
| Sei Investments Co. | 0.01% | Add +9.0% | 19,115 | $8.8M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -23.7% | 18,715 | $8.6M |
| Neuberger Berman Group LLC | 0.01% | New | 18,531 | $8.5M |
| Rockefeller Capital Management L.P. | 0.02% | Add +2.8% | 18,451 | $8.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Add +361.6% | 18,363 | $8.4M |
| Rhenman & Partners Asset Management AB | 0.93% | New | 18,250 | $8.4M |
| Cubist Systematic Strategies, LLC | 0.12% | New | 17,889 | $8.2M |
| WCM Investment Management, LLC | 0.02% | New | 18,291 | $8.1M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -26.0% | 17,327 | $7.9M |
| Schroder Investment Management Group | 0.01% | Reduce -50.0% | 16,612 | $7.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +388.3% | 15,288 | $7.0M |
| AXA Investment Managers S.A. | 0.02% | — | 15,036 | $6.9M |
| Resolute Capital Asset Partners LLC | 3.60% | New | 15,000 | $6.9M |
| Envestnet Asset Management Inc. | 0.00% | Add +0.4% | 14,566 | $6.7M |
"% of holder's portfolio" is MDGL's weight in each manager's 13F, not the share of Madrigal Pharmaceuticals Inc. the manager owns.