Madrigal PharmaceuticalsMDGL
13F holders, Q3 2025 (September 30)352holders +47
84new positions
35sold out
10famous investors
$458.48avg. 13F price*
At the end of Q3 2025, 352 institutions reported holding Madrigal Pharmaceuticals Inc. (MDGL) in their 13F filings, up 47 from Q2 2025. 84 opened new positions and 35 sold out. The largest holders were Baker Bros. Advisors LP ($982.3M), RTW Investments, LP ($914.4M) and Paulson & Co. ($874.9M). 10 famous investors held it, including John Paulson (29.5% of Paulson & Co.'s portfolio), Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio) and Ray Dalio (0.0% of Bridgewater Associates's portfolio).
- Company
- Madrigal Pharmaceuticals Inc.
- CUSIP
- 558868105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 84 | $328.6M |
| Exits | 35 | $63.2M |
All 13F filers, Q2 2025 → Q3 2025: 2,487,480 shares bought and 2,487,519 shares sold, net −39 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 352 holders
| Baker Bros. Advisors LP | 7.12% | Add +8.4% | 2,141,701 | $982.3M |
| RTW Investments, LP | 11.27% | No change | 1,993,687 | $914.4M |
| Paulson & Co. | 29.46% | Reduce -8.7% | 1,907,523 | $874.9M |
| Janus Henderson Group PLC | 0.39% | Reduce -15.9% | 1,842,690 | $845.3M |
| Avoro Capital Advisors LLC | 10.88% | Reduce -2.2% | 1,833,000 | $840.7M |
| Vanguard Group Inc. | 0.01% | Reduce -3.5% | 1,812,054 | $831.1M |
| BlackRock, Inc. | 0.01% | Add +8.4% | 1,559,712 | $715.4M |
| State Street Corp. | 0.01% | Reduce -4.7% | 658,097 | $301.8M |
| Geode Capital Management, LLC | 0.01% | Add +7.7% | 446,233 | $204.7M |
| William Blair Investment Management, LLC | 0.49% | Add +17.6% | 411,802 | $188.9M |
| Wellington Management Group LLP | 0.03% | Add +5381.2% | 404,455 | $185.5M |
| FMR LLC | 0.01% | Reduce -9.9% | 401,136 | $184.0M |
| Goldman Sachs Group Inc. | 0.03% | Add +103.4% | 386,100 | $177.1M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -30.7% | 352,520 | $161.7M |
| Invesco Ltd. | 0.02% | Add +49.5% | 299,565 | $137.4M |
| Polar Capital Holdings Plc | 0.59% | Add +17.6% | 265,154 | $121.6M |
| Morgan Stanley | 0.01% | Add +0.7% | 249,647 | $114.5M |
| Bank of America Corp. | 0.01% | Reduce -11.9% | 244,292 | $112.0M |
| Hood River Capital Management LLC | 1.31% | Reduce -0.8% | 242,808 | $111.4M |
| UBS Group AG | 0.02% | Reduce -57.0% | 217,343 | $99.7M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +39.6% | 213,652 | $98.0M |
| Artisan Partners Limited Partnership | 0.14% | Add +2.3% | 206,254 | $94.6M |
| Erste Asset Management GmbH | 0.86% | No change | 201,100 | $89.1M |
| Pictet Asset Management Holding SA | 0.08% | Reduce -7.9% | 191,796 | $87.7M |
| American Century Companies Inc. | 0.04% | Reduce -1.3% | 165,615 | $76.0M |
| Northern Trust Corp. | 0.01% | Add +12.0% | 159,988 | $73.4M |
| Rock Springs Capital Management LP | 3.71% | Reduce -1.8% | 137,746 | $63.2M |
| Fiera Capital Corp | 0.19% | Reduce -2.2% | 127,800 | $58.6M |
| ArrowMark Colorado Holdings LLC | 1.05% | Reduce -14.9% | 123,259 | $56.5M |
| Renaissance Technologies | 0.07% | Add +1013.7% | 120,682 | $55.4M |
| Alkeon Capital Management LLC | 0.25% | New | 120,000 | $55.0M |
| Armistice Capital, LLC | 1.73% | Reduce -3.2% | 119,982 | $55.0M |
| Driehaus Capital Management LLC | 0.38% | New | 115,974 | $53.2M |
| Affinity Asset Advisors, LLC | 5.06% | Add +43.8% | 115,000 | $52.7M |
| Susquehanna International Group, LLP | 0.07% | Add +4.5% | 104,818 | $48.1M |
| Woodline Partners LP | 0.22% | Reduce -34.9% | 103,847 | $47.6M |
| Lord, Abbett & Co. LLC | 0.15% | Add +21.3% | 102,143 | $46.8M |
| MPM Bioimpact LLC | 7.54% | No change | 100,415 | $46.1M |
| Bank of New York Mellon Corp | 0.01% | Add +9.9% | 97,779 | $44.8M |
| D. E. Shaw & Co. | 0.04% | Reduce -14.1% | 96,182 | $44.1M |
| Jane Street Group, LLC | 0.05% | New | 95,734 | $43.9M |
| Adage Capital Partners Gp, L.L.C. | 0.06% | Reduce -76.5% | 88,500 | $40.6M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.12% | Reduce -14.3% | 85,773 | $39.3M |
| Balyasny Asset Management L.P. | 0.08% | Add +138.8% | 82,401 | $37.8M |
| Franklin Resources Inc. | 0.01% | Add +24.5% | 75,570 | $34.7M |
| EcoR1 Capital, LLC | 1.65% | No change | 75,000 | $34.4M |
| Nuveen, LLC | 0.01% | Add +77.5% | 73,715 | $33.8M |
| BNP Paribas Financial Markets | 0.03% | Add +2.5% | 70,757 | $32.5M |
| Raymond James Financial Inc. | 0.01% | Add +28.5% | 70,584 | $32.4M |
| New York State Common Retirement Fund | 0.04% | Add +13.4% | 69,273 | $31.8M |
| Soleus Capital Management, L.P. | 1.68% | Add +754.2% | 68,336 | $31.3M |
| Tri Locum Partners LP | 7.14% | Reduce -30.8% | 67,706 | $31.1M |
| Voya Investment Management LLC | 0.03% | Add +16.3% | 59,437 | $27.3M |
| Iron Triangle Partners LP | 3.81% | New | 58,378 | $26.8M |
| Ensign Peak Advisors, Inc | 0.04% | Add +10.1% | 53,267 | $24.4M |
| EULAV Asset Management | 0.54% | Add +64.5% | 51,000 | $23.4M |
| Emerald Advisers, LLC | 0.75% | Reduce -4.5% | 50,737 | $23.3M |
| Mirae Asset Global Investments Co., Ltd. | 0.07% | Reduce -28.3% | 50,578 | $23.2M |
| Candriam S.C.A. | 0.12% | No change | 49,965 | $22.9M |
| Barclays PLC | 0.01% | Reduce -20.4% | 49,912 | $22.9M |
| Citadel Advisors | 0.02% | Reduce -76.7% | 48,372 | $22.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -14.4% | 47,824 | $21.9M |
| Russell Investments Group, Ltd. | 0.02% | Add +32.0% | 44,885 | $20.6M |
| Rheos Capital Works Inc. | 1.11% | No change | 43,215 | $19.8M |
| Point72 Asset Management | 0.04% | Reduce -62.8% | 41,233 | $18.9M |
| Tao Capital Management LP | 14.22% | Reduce -63.6% | 41,000 | $18.8M |
| Wells Fargo & Company | 0.00% | Add +3.1% | 37,818 | $17.3M |
| Deutsche Bank AG | 0.01% | Add +54.9% | 37,342 | $17.1M |
| Alliancebernstein L.P. | 0.01% | Add +68.0% | 35,695 | $16.4M |
| Emerald Mutual Fund Advisers Trust | 0.83% | Reduce -5.0% | 35,091 | $16.1M |
| Ally Bridge Group (NY) LLC | 12.54% | New | 32,662 | $15.0M |
| Gilder Gagnon Howe & Co. LLC | 0.14% | Reduce -2.2% | 30,848 | $14.1M |
| Squarepoint Ops LLC | 0.03% | Add +583.2% | 29,936 | $13.7M |
| Steadfast Capital Management LP | 0.25% | New | 29,800 | $13.7M |
| Swiss National Bank | 0.01% | Add +1.8% | 27,900 | $12.8M |
| Bridgewater Associates | 0.05% | New | 27,785 | $12.7M |
| Groupama Asset Managment | 0.19% | Reduce -32.9% | 27,444 | $12.6M |
| Rhumbline Advisers | 0.01% | Add +3.4% | 27,263 | $12.5M |
| California Public Employees Retirement System | 0.01% | Reduce -12.6% | 24,097 | $11.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -41.0% | 23,476 | $10.8M |
| LPL Financial LLC | 0.00% | Add +59.6% | 22,538 | $10.3M |
| Segall Bryant & Hamill, LLC | 0.14% | New | 22,490 | $10.3M |
| Legal & General Group Plc | 0.00% | Reduce -6.2% | 21,671 | $9.9M |
| Man Group plc | 0.02% | Add +1460.2% | 21,328 | $9.8M |
| Jump Financial, LLC | 0.13% | New | 20,956 | $9.6M |
| Royal Bank of Canada | 0.00% | Add +110.1% | 20,173 | $9.3M |
| Sei Investments Co. | 0.01% | Add +9.0% | 19,115 | $8.8M |
| Rafferty Asset Management, LLC | 0.03% | Reduce -23.7% | 18,715 | $8.6M |
| Neuberger Berman Group LLC | 0.01% | New | 18,531 | $8.5M |
| Rockefeller Capital Management L.P. | 0.02% | Add +2.8% | 18,451 | $8.5M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Add +361.6% | 18,363 | $8.4M |
| Rhenman & Partners Asset Management AB | 0.93% | New | 18,250 | $8.4M |
| Cubist Systematic Strategies, LLC | 0.12% | New | 17,889 | $8.2M |
| WCM Investment Management, LLC | 0.02% | New | 18,291 | $8.1M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -26.0% | 17,327 | $7.9M |
| Schroder Investment Management Group | 0.01% | Reduce -50.0% | 16,612 | $7.4M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +388.3% | 15,288 | $7.0M |
| AXA Investment Managers S.A. | 0.02% | — | 15,036 | $6.9M |
| Resolute Capital Asset Partners LLC | 3.60% | New | 15,000 | $6.9M |
| Envestnet Asset Management Inc. | 0.00% | Add +0.4% | 14,566 | $6.7M |
| California State Teachers Retirement System | 0.01% | Reduce -1.7% | 13,891 | $6.4M |
| Macquarie Group Ltd. | 0.01% | Reduce -31.3% | 13,493 | $6.2M |
| TD Asset Management Inc | 0.01% | Reduce -42.7% | 13,324 | $6.1M |
| University of Wisconsin Foundation | 5.05% | Reduce -73.1% | 13,007 | $6.0M |
| Ameriprise Financial Inc. | 0.00% | Add +54.6% | 12,997 | $6.0M |
| Hennion & Walsh Asset Management, Inc. | 0.21% | Add +1.4% | 12,847 | $5.9M |
| Journey Strategic Wealth LLC | 0.17% | Reduce -1.9% | 12,828 | $5.9M |
| Mutual of America Capital Management LLC | 0.06% | Reduce -1.1% | 12,179 | $5.6M |
| Principal Financial Group Inc. | 0.00% | Add +31.1% | 12,068 | $5.5M |
| Nan Fung Group Holdings Ltd | 9.13% | No change | 11,872 | $5.4M |
| First Light Asset Management, LLC | 0.50% | New | 11,539 | $5.3M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Reduce -9.1% | 11,356 | $5.2M |
| State of Wisconsin Investment Board | 0.01% | Add +20.9% | 10,875 | $5.0M |
| MetLife Investment Management, LLC | 0.02% | Add +7.4% | 10,807 | $5.0M |
| Informed Momentum Co LLC | 0.56% | New | 10,844 | $4.9M |
| Castleark Management LLC | 0.13% | New | 9,926 | $4.6M |
| Citigroup Inc. | 0.00% | Reduce -47.8% | 9,648 | $4.4M |
| Canada Pension Plan Investment Board | 0.00% | Add +66.7% | 9,000 | $4.1M |
| Creative Planning | 0.00% | Add +63.3% | 8,430 | $3.9M |
| EFG Asset Management (North America) Corp. | 0.49% | New | 8,294 | $3.8M |
| Stempoint Capital LP | 0.76% | Reduce -84.4% | 8,207 | $3.8M |
| Algert Global LLC | 0.06% | Reduce -15.7% | 8,030 | $3.7M |
| DekaBank Deutsche Girozentrale | 0.01% | No change | 8,000 | $3.5M |
| Intech Investment Management LLC | 0.03% | Reduce -26.4% | 6,670 | $3.1M |
| AQR Capital Management | 0.00% | Add +108.0% | 6,586 | $3.0M |
| F/m Investments LLC | 0.11% | Add +4.4% | 6,322 | $2.9M |
| Susquehanna Portfolio Strategies, LLC | 0.05% | No change | 6,250 | $2.9M |
| Prudential Financial Inc. | 0.00% | Add +15.3% | 5,913 | $2.7M |
| Dimensional Fund Advisors LP | 0.00% | Add +49.8% | 5,799 | $2.7M |
| Victory Capital Management Inc. | 0.00% | Reduce -30.4% | 5,763 | $2.6M |
| Verition Fund Management LLC | 0.02% | Add +30.3% | 5,630 | $2.6M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -24.2% | 5,225 | $2.4M |
| SG Americas Securities, LLC | 0.01% | New | 5,191 | $2.4M |
| Police & Firemen's Retirement System of New Jersey | 0.02% | Add +34.4% | 5,165 | $2.4M |
| Los Angeles Capital Management LLC | 0.01% | Reduce -0.5% | 5,124 | $2.4M |
| Assetmark, Inc. | 0.01% | Add +3.3% | 5,058 | $2.3M |
| ADAR1 Capital Management, LLC | 0.22% | Add +364.4% | 4,895 | $2.2M |
| Wolverine Trading, LLC | 0.05% | Add +420.2% | 5,056 | $2.2M |
| Fieldview Capital Management, LLC | 0.35% | New | 4,658 | $2.1M |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -14.3% | 4,609 | $2.1M |
| Martingale Asset Management L P | 0.05% | Reduce -17.1% | 4,515 | $2.1M |
| Calamos Advisors LLC | 0.01% | New | 4,485 | $2.1M |
| Handelsbanken Fonder AB | 0.01% | No change | 4,400 | $2.0M |
| Arizona State Retirement System | 0.01% | Add +1.9% | 4,255 | $2.0M |
| Profund Advisors LLC | 0.06% | Reduce -19.0% | 4,202 | $1.9M |
| Orion Porfolio Solutions, LLC | 0.01% | Add +12.4% | 4,091 | $1.9M |
| Shikiar Asset Management Inc. | 0.51% | Reduce -20.0% | 4,000 | $1.8M |
| ProShare Advisors LLC | 0.00% | Reduce -7.4% | 3,974 | $1.8M |
| China Universal Asset Management Co., Ltd. | 0.15% | Reduce -12.4% | 3,907 | $1.8M |
| Federated Hermes, Inc. | 0.00% | New | 3,885 | $1.8M |
| Knights of Columbus Asset Advisors LLC | 0.10% | Reduce -16.4% | 3,848 | $1.8M |
| First Trust Advisors LP | 0.00% | Add +117.3% | 3,795 | $1.7M |
| Cetera Investment Advisers | 0.00% | Add +100.3% | 3,726 | $1.7M |
| Entropy Technologies, LP | 0.13% | Add +94.6% | 3,702 | $1.7M |
| NFSG Corp | 0.25% | Add +1.9% | 3,642 | $1.7M |
| Cinctive Capital Management LP | 0.08% | Reduce -24.4% | 3,606 | $1.7M |
| Allworth Financial LP | 0.01% | Add +0.4% | 3,548 | $1.6M |
| HighVista Strategies LLC | 0.40% | Add +53.5% | 3,537 | $1.6M |
| Teacher Retirement System of Texas | 0.01% | Reduce -8.5% | 3,531 | $1.6M |
| Ami Asset Management Corp. | 0.09% | Reduce -0.4% | 3,426 | $1.6M |
| Farallon Capital Management, L.L.C. | 0.01% | No change | 3,319 | $1.5M |
| Dana Investment Advisors, Inc. | 0.04% | Add +10.3% | 3,181 | $1.5M |
| Allianz Asset Management GmbH | 0.00% | Add +106.7% | 3,100 | $1.4M |
| KLP Kapitalforvaltning As | 0.01% | No change | 3,000 | $1.4M |
| Engineers Gate Manager LP | 0.02% | Reduce -33.7% | 2,934 | $1.3M |
| Teachers Retirement System of the State of Kentucky | 0.01% | New | 2,872 | $1.3M |
| Stifel Financial Corp. | 0.00% | Reduce -17.8% | 2,609 | $1.2M |
| Quadrant Capital Group LLC | 0.04% | No change | 2,605 | $1.2M |
| Baron Capital (BAMCO) | 0.00% | New | 2,600 | $1.2M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -32.7% | 2,588 | $1.2M |
| Snowden Capital Advisors LLC | 0.03% | Add +18.5% | 2,510 | $1.2M |
| FORA Capital, LLC | 0.20% | New | 2,503 | $1.1M |
| Strid Group, LLC | 0.15% | No change | 2,500 | $1.1M |
| Commonwealth Equity Services, LLC | 0.00% | Add +34.1% | 2,477 | $1.1M |
| First National Trust Co | 0.04% | Reduce -69.1% | 2,476 | $1.1M |
| Pathstone Holdings, LLC | 0.00% | New | 2,436 | $1.1M |
| J. Safra Sarasin Holding AG | 0.02% | Reduce -64.9% | 2,397 | $1.1M |
| Bellevue Group AG | 0.02% | Add +117.5% | 2,393 | $1.1M |
| Cwm, LLC | 0.00% | Reduce -8.5% | 2,360 | $1.1M |
| Fox Run Management, L.L.C. | 0.17% | New | 2,318 | $1.1M |
| Tidal Investments LLC | 0.00% | New | 2,209 | $1.0M |
| STRS Ohio | 0.00% | Add +57.1% | 2,200 | $1.0M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -0.5% | 2,123 | $974K |
| D.A. Davidson & Co. | 0.01% | Add +33.4% | 2,071 | $950K |
| Knott David M Jr | 0.38% | No change | 2,000 | $917K |
| Sigma Planning Corp | 0.03% | New | 2,000 | $917K |
| CIBC Bancorp USA Inc. | 0.01% | — | 1,983 | $910K |
| Baader Bank Aktiengesellschaft | 0.07% | New | 1,935 | $885K |
| Mariner, LLC | 0.00% | Add +17.5% | 1,821 | $835K |
| Millennium Management | 0.00% | Reduce -83.4% | 1,798 | $825K |
| Gsa Capital Partners LLP | 0.07% | New | 1,739 | $798K |
| Guggenheim Capital LLC | 0.01% | Reduce -20.3% | 1,625 | $745K |
| Tema ETFs LLC | 0.06% | Reduce -10.0% | 1,621 | $743K |
| NEOS Investment Management LLC | 0.01% | Reduce -10.0% | 1,621 | $743K |
| R Squared Ltd | 0.32% | Reduce -8.5% | 1,619 | $743K |
| New York Life Investment Management LLC | 0.01% | Reduce -2.6% | 1,610 | $738K |
| Kestra Advisory Services, LLC | 0.00% | Reduce -5.9% | 1,567 | $719K |
| Ameritas Investment Partners, Inc. | 0.02% | Reduce -9.9% | 1,554 | $713K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 1,608 | $711K |
| NJ State Employees Deferred Compensation Plan | 0.08% | No change | 1,500 | $688K |
| Virtus Investment Advisers, LLC | 0.20% | No change | 1,495 | $686K |
| AlTi Global, Inc. | 0.02% | No change | 1,492 | $684K |
| Sanctuary Advisors, LLC | 0.00% | Add +15.1% | 1,465 | $672K |
| Xponance LLC | 0.01% | Add +11.6% | 1,460 | $670K |
| J. Goldman & Co LP | 0.03% | Reduce -59.2% | 1,449 | $665K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 1,433 | $657K |
| MML Investors Services, LLC | 0.00% | Reduce -8.0% | 1,390 | $638K |
| Brevan Howard Capital Management LP | 0.01% | Add +17.9% | 1,375 | $631K |
| Bayforest Capital Ltd | 0.30% | Reduce -35.5% | 1,360 | $624K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Add +2.7% | 1,271 | $583K |
| Verity Asset Management, Inc. | 0.19% | Reduce -26.6% | 1,260 | $578K |
| Dark Forest Capital Management LP | 0.02% | New | 1,259 | $577K |
| B. Metzler seel. Sohn & Co. AG | 0.00% | New | 1,221 | $560K |
| Bryce Point Capital, LLC | 0.65% | New | 1,169 | $536K |
| Peak Financial Advisors LLC | 0.25% | New | 1,154 | $529K |
| HighTower Advisors, LLC | 0.00% | Reduce -16.9% | 1,127 | $517K |
| Boothbay Fund Management, LLC | 0.01% | New | 1,117 | $512K |
| Oppenheimer Asset Management Inc. | 0.01% | Reduce -1.3% | 1,106 | $507K |
| Gladstone Institutional Advisory LLC | 0.02% | New | 1,093 | $501K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +10.7% | 1,089 | $499K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,084 | $497K |
| JGP Global Gestao de Recursos Ltda. | 0.28% | Reduce -16.0% | 1,042 | $478K |
| Landscape Capital Management, L.L.C. | 0.03% | Reduce -82.8% | 1,010 | $463K |
| Atria Investments, Inc | 0.01% | Reduce -11.9% | 1,010 | $463K |
| Blair William & Co. | 0.00% | No change | 1,000 | $459K |
| Optimize Financial Inc. | 0.23% | New | 980 | $449K |
| Syon Capital LLC | 0.02% | Add +0.2% | 965 | $443K |
| Cerity Partners LLC | 0.00% | Reduce -15.0% | 963 | $442K |
| Chicago Partners Investment Group LLC | 0.01% | Add +5.8% | 1,025 | $440K |
| Penserra Capital Management LLC | 0.01% | New | 954 | $437K |
| Tudor Investment Corporation | 0.00% | New | 926 | $425K |
| O'shaughnessy Asset Management, LLC | 0.00% | New | 856 | $393K |
| Cannon Global Investment Management, LLC | 0.93% | No change | 800 | $367K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.54% | New | 792 | $363K |
| Osaic Holdings, Inc. | 0.00% | Reduce -90.8% | 802 | $362K |
| Park Avenue Securities LLC | 0.00% | Add +12.4% | 786 | $360K |
| Pitcairn Co. | 0.03% | Reduce -3.1% | 771 | $354K |
| QRG Capital Management, Inc. | 0.00% | Add +10.9% | 771 | $354K |
| Comerica Bank | 0.00% | Add +0.3% | 759 | $348K |
| Dorsey & Whitney Trust CO LLC | 0.02% | No change | 752 | $345K |
| Sectoral Asset Management Inc. | 0.21% | No change | 730 | $335K |
| Bridgefront Capital, LLC | 0.10% | Reduce -66.6% | 716 | $328K |
| Centaurus Financial, Inc. | 0.02% | Add +5.0% | 709 | $325K |
| Composition Wealth, LLC | 0.00% | No change | 703 | $322K |
| Marshall Wace, LLP | 0.00% | Reduce -98.7% | 700 | $321K |
| Intrust Bank NA | 0.03% | New | 674 | $309K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +1.0% | 708 | $309K |
| Transcend Capital Advisors, LLC | 0.02% | New | 673 | $309K |
| Point72 Hong Kong Ltd | 0.01% | New | 669 | $307K |
| Swiss Life Asset Management Ltd | 0.00% | New | 646 | $296K |
| Scientech Research LLC | 0.10% | New | 634 | $291K |
| CIBC Asset Management Inc | 0.00% | New | 626 | $287K |
| OneDigital Investment Advisors LLC | 0.00% | New | 616 | $283K |
| Amalgamated Bank | 0.00% | Reduce -3.0% | 603 | $277K |
| Truist Financial Corp. | 0.00% | New | 603 | $277K |
| Abel Hall, LLC | 0.11% | New | 590 | $271K |
| Aigen Investment Management, LP | 0.04% | New | 585 | $268K |
| PharVision Advisers, LLC | 0.15% | New | 582 | $267K |
| Integrated Investment Consultants, LLC | 0.04% | New | 567 | $260K |
| Quantitative Investment Management, LLC | 0.04% | New | 569 | $260K |
| Captrust Financial Advisors | 0.00% | New | 566 | $260K |
| Inceptionr LLC | 0.06% | New | 565 | $259K |
| Palumbo Wealth Management LLC | 0.08% | New | 545 | $250K |
| Praxis Investment Management Inc. | 0.01% | New | 540 | $248K |
| TCI Wealth Advisors, Inc. | 0.01% | New | 517 | $237K |
| Coldstream Capital Management Inc. | 0.00% | New | 512 | $235K |
| Kozak & Associates, Inc. | 0.05% | Add +30.9% | 424 | $235K |
| Beirne Wealth Consulting Services, LLC | 0.06% | New | 508 | $233K |
| Bayesian Capital Management, LP | 0.05% | Reduce -64.4% | 491 | $225K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -14.0% | 480 | $220K |
| Sovran Advisors, LLC | 0.02% | New | 500 | $214K |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0.00% | New | 500 | $212K |
| Everhart Financial Group, Inc. | 0.02% | Reduce -66.7% | 459 | $211K |
| Kestra Investment Management, LLC | 0.01% | Add +57.9% | 442 | $203K |
| Nisa Investment Advisors, LLC | 0.00% | Add +62.9% | 435 | $200K |
| KBC Group NV | 0.00% | No change | 414 | $190K |
| US Bancorp \de | 0.00% | Add +0.3% | 388 | $178K |
| IFP Advisors, Inc | 0.00% | Add +5.4% | 371 | $170K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -80.7% | 357 | $164K |
| PNC Financial Services Group, Inc. | 0.00% | Add +7.8% | 262 | $120K |
| Parallel Advisors, LLC | 0.00% | Reduce -4.8% | 259 | $119K |
| UMB Bank, n.a. | 0.00% | Reduce -1.3% | 230 | $105K |
| Montag A & Associates Inc. | 0.00% | No change | 194 | $89K |
| Jones Financial Companies LLLP | 0.00% | Add +1.5% | 199 | $84K |
| Point72 (DIFC) Ltd | 0.01% | Add +4000.0% | 164 | $75K |
| Point72 Europe (London) LLP | 0.00% | New | 148 | $68K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +3.8% | 137 | $63K |
| Optiver Holding B.V. | 0.00% | Add +15.3% | 136 | $62K |
| Smartleaf Asset Management LLC | 0.00% | Add +143.1% | 124 | $55K |
| Signaturefd, LLC | 0.00% | Reduce -8.7% | 115 | $53K |
| Johnson Financial Group, Inc. | 0.00% | New | 110 | $50K |
| Farther Finance Advisors, LLC | 0.00% | Add +14.3% | 104 | $48K |
| Compagnie Lombard Odier SCmA | 0.00% | No change | 104 | $48K |
| Spire Wealth Management | 0.00% | Reduce -60.0% | 100 | $46K |
| GAMMA Investing LLC | 0.00% | Add +114.3% | 90 | $41K |
| Quarry LP | 0.01% | New | 86 | $39K |
| Aster Capital Management (DIFC) Ltd | 0.02% | New | 85 | $39K |
| First Horizon Corp. | 0.00% | — | 75 | $34K |
| Global Retirement Partners, LLC | 0.00% | Add +221.7% | 74 | $34K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -2.7% | 73 | $33K |
| Mather Group, Llc. | 0.00% | New | 73 | $33K |
| Principal Securities, Inc. | 0.00% | Reduce -6.6% | 71 | $33K |
| NewEdge Advisors, LLC | 0.00% | No change | 70 | $32K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -9.1% | 70 | $32K |
| CoreCap Advisors, LLC | 0.00% | No change | 68 | $31K |
| Eastern Bank | 0.00% | No change | 65 | $30K |
| Aventura Private Wealth, LLC | 0.01% | No change | 62 | $28K |
| Accent Capital Management, LLC | 0.01% | Reduce -39.4% | 57 | $26K |
| Leonteq Securities AG | 0.00% | New | 56 | $26K |
| McIlrath & Eck, LLC | 0.00% | No change | 52 | $24K |
| AlphaQuest LLC | 0.00% | Reduce -36.6% | 52 | $24K |
| CIBC Private Wealth Group LLC | 0.00% | New | 51 | $23K |
| Lanark Financial, Inc. | 0.00% | No change | 48 | $22K |
| Sterling Capital Management LLC | 0.00% | Add +9.8% | 45 | $21K |
| Covestor Ltd | 0.01% | No change | 41 | $19K |
| Valley National Advisers Inc. | 0.00% | Add +11.4% | 39 | $17K |
| Rise Advisors, LLC | 0.01% | No change | 35 | $16K |
| Rakuten Securities, Inc. | 0.01% | Add +15.4% | 30 | $14K |
| Huntington National Bank | 0.00% | Add +15.4% | 30 | $14K |
| Bradley & Co. Private Wealth Management, LLC | 0.01% | No change | 27 | $12K |
| CI Investments Inc. | 0.00% | Reduce -3.7% | 26 | $12K |
| Rothschild Investment LLC | 0.00% | Reduce -11.1% | 24 | $11K |
| MV Capital Management, Inc. | 0.00% | No change | 22 | $10K |
| Larson Financial Group LLC | 0.00% | New | 15 | $7K |
| Arax Advisory Partners | 0.00% | New | 15 | $7K |
| Vermillion & White Wealth Management Group, LLC | 0.00% | No change | 14 | $6K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +1100.0% | 12 | $6K |
| Parkside Financial Bank & Trust | 0.00% | Add +25.0% | 10 | $5K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 10 | $5K |
| Cape Investment Advisory, Inc. | 0.00% | No change | 9 | $4K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 9 | $4K |
| Signature Resources Capital Management, LLC | 0.00% | New | 7 | $3K |
| Meeder Asset Management Inc. | 0.00% | New | 7 | $3K |
| FNY Investment Advisers, LLC | 0.00% | New | 7 | $3K |
| Webster Bank, N. A. | 0.00% | No change | 6 | $3K |
| MAI Capital Management | 0.00% | Reduce -50.0% | 6 | $3K |
| JPL Wealth Management, LLC | 0.00% | New | 5 | $2K |
| Bell Investment Advisors, Inc | 0.00% | No change | 5 | $2K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 5 | $2K |
| Bessemer Group Inc. | 0.00% | No change | 5 | $2K |
| Retirement Wealth Solutions LLC | 0.00% | New | 4 | $2K |
| Park Place Capital Corp | 0.00% | No change | 4 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 4 | $2K |
| Marquette Asset Management, LLC | 0.00% | New | 3 | $1K |
| Tortoise Investment Management, LLC | 0.00% | Add +50.0% | 3 | $1K |
| SouthState Bank Corp | 0.00% | No change | 2 | $918 |
| Caitlin John, LLC | 0.00% | New | 2 | $917 |
| Transamerica Financial Advisors, LLC | 0.00% | New | 2 | $917 |
| Physician Wealth Advisors, Inc. | 0.00% | New | 1 | $459 |
| Fortitude Family Office, LLC | 0.00% | No change | 1 | $459 |
| TD Capital Management LLC | 0.00% | No change | 1 | $459 |
| Bogart Wealth, LLC | 0.00% | New | 1 | $459 |
"% of holder's portfolio" is MDGL's weight in each manager's 13F, not the share of Madrigal Pharmaceuticals Inc. the manager owns.