Madrigal PharmaceuticalsMDGL
13F holders, Q4 2025 (December 31)387holders +35
71new positions
39sold out
10famous investors
$582.01avg. 13F price*
At the end of Q4 2025, 387 institutions reported holding Madrigal Pharmaceuticals Inc. (MDGL) in their 13F filings, up 35 from Q3 2025. 71 opened new positions and 39 sold out. The largest holders were Baker Bros. Advisors LP ($1.2B), RTW Investments, LP ($1.2B) and Vanguard Group Inc. ($1.1B). 10 famous investors held it, including John Paulson (30.5% of Paulson & Co.'s portfolio), Steve Cohen (0.1% of Point72 Asset Management's portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- Madrigal Pharmaceuticals Inc.
- CUSIP
- 558868105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 71 | $131.2M |
| Exits | 39 | $138.8M |
All 13F filers, Q3 2025 → Q4 2025: 1,939,328 shares bought and 1,931,422 shares sold, net +7,906 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 387 holders
| Baker Bros. Advisors LP | 7.33% | No change | 2,141,701 | $1.2B |
| RTW Investments, LP | 11.63% | No change | 1,993,687 | $1.2B |
| Vanguard Group Inc. | 0.02% | Reduce -0.2% | 1,808,894 | $1.1B |
| Avoro Capital Advisors LLC | 10.35% | Reduce -1.4% | 1,807,500 | $1.1B |
| Paulson & Co. | 30.48% | Reduce -10.5% | 1,707,522 | $994.4M |
| BlackRock, Inc. | 0.02% | Add +5.5% | 1,644,750 | $957.8M |
| Janus Henderson Group PLC | 0.41% | Reduce -14.0% | 1,584,843 | $918.2M |
| State Street Corp. | 0.01% | Reduce -11.4% | 583,003 | $339.5M |
| Wellington Management Group LLP | 0.05% | Add +14.1% | 461,402 | $268.7M |
| Geode Capital Management, LLC | 0.02% | Add +1.2% | 451,743 | $263.1M |
| FMR LLC | 0.01% | Add +9.5% | 439,398 | $255.9M |
| Bank of America Corp. | 0.02% | Add +70.3% | 416,025 | $242.3M |
| Invesco Ltd. | 0.02% | Add +21.9% | 365,314 | $212.7M |
| William Blair Investment Management, LLC | 0.58% | Reduce -14.0% | 354,220 | $206.3M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -11.0% | 313,659 | $182.7M |
| Goldman Sachs Group Inc. | 0.03% | Reduce -20.8% | 305,847 | $178.1M |
| Polar Capital Holdings Plc | 0.72% | Add +1.9% | 270,151 | $157.3M |
| Armistice Capital, LLC | 3.79% | Add +121.5% | 265,705 | $154.7M |
| Hood River Capital Management LLC | 1.58% | Add +2.0% | 247,560 | $144.2M |
| Lord, Abbett & Co. LLC | 0.46% | Add +139.7% | 244,796 | $142.6M |
| Alkeon Capital Management LLC | 0.61% | Add +100.0% | 240,000 | $139.8M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +2.5% | 219,099 | $127.6M |
| Artisan Partners Limited Partnership | 0.18% | Reduce -3.7% | 198,693 | $115.7M |
| Norges Bank | 0.01% | — | 196,393 | $114.4M |
| Deutsche Bank AG | 0.04% | Add +414.5% | 192,109 | $111.9M |
| American Century Companies Inc. | 0.05% | Add +11.8% | 185,116 | $107.8M |
| Pictet Asset Management Holding SA | 0.10% | Reduce -5.1% | 181,949 | $106.0M |
| Fiera Capital Corp | 0.31% | Add +32.6% | 169,456 | $98.7M |
| Northern Trust Corp. | 0.01% | Reduce -5.1% | 151,802 | $88.4M |
| Morgan Stanley | 0.01% | Reduce -39.7% | 150,462 | $87.6M |
| Erste Asset Management GmbH | 0.69% | Reduce -29.8% | 141,100 | $82.3M |
| Rock Springs Capital Management LP | 4.19% | Add +1.4% | 139,618 | $81.3M |
| Bank of New York Mellon Corp | 0.01% | Add +40.0% | 136,869 | $79.7M |
| Point72 Asset Management | 0.12% | Add +206.6% | 126,435 | $73.6M |
| Woodline Partners LP | 0.28% | Add +21.0% | 125,659 | $73.2M |
| Nuveen, LLC | 0.02% | Add +60.6% | 118,363 | $68.9M |
| Driehaus Capital Management LLC | 0.44% | Reduce -3.7% | 111,666 | $65.0M |
| UBS Group AG | 0.01% | Reduce -52.8% | 102,641 | $59.8M |
| MPM Bioimpact LLC | 6.45% | Reduce -3.6% | 96,780 | $56.4M |
| Jane Street Group, LLC | 0.07% | Reduce -2.7% | 93,114 | $54.2M |
| D. E. Shaw & Co. | 0.04% | Reduce -7.9% | 88,554 | $51.6M |
| Franklin Resources Inc. | 0.01% | Add +13.9% | 86,076 | $50.1M |
| Tri Locum Partners LP | 6.50% | Add +27.1% | 86,023 | $50.1M |
| Renaissance Technologies | 0.08% | Reduce -30.5% | 83,862 | $48.8M |
| ArrowMark Colorado Holdings LLC | 1.06% | Reduce -33.0% | 82,624 | $48.1M |
| New York State Common Retirement Fund | 0.06% | Add +9.6% | 75,933 | $44.2M |
| Squarepoint Ops LLC | 0.09% | Add +150.3% | 74,934 | $43.6M |
| BNP Paribas Financial Markets | 0.03% | Add +4.2% | 73,707 | $42.9M |
| First Light Asset Management, LLC | 2.98% | Add +479.2% | 66,831 | $38.9M |
| Raymond James Financial Inc. | 0.01% | Reduce -5.5% | 66,724 | $38.9M |
| Susquehanna International Group, LLP | 0.05% | Reduce -38.5% | 64,466 | $37.5M |
| Voya Investment Management LLC | 0.04% | Add +8.1% | 64,254 | $37.4M |
| Candriam S.C.A. | 0.19% | Add +27.9% | 63,906 | $37.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.09% | Reduce -32.0% | 58,295 | $33.9M |
| Jain Global LLC | 0.31% | New | 52,721 | $30.7M |
| Ensign Peak Advisors, Inc | 0.05% | Reduce -4.2% | 51,010 | $29.7M |
| Mirae Asset Global Investments Co., Ltd. | 0.08% | Add +0.1% | 50,631 | $29.5M |
| EULAV Asset Management | 0.76% | Reduce -3.9% | 49,000 | $28.5M |
| Russell Investments Group, Ltd. | 0.03% | Add +7.3% | 48,159 | $28.0M |
| Canada Pension Plan Investment Board | 0.02% | Add +412.4% | 46,120 | $26.9M |
| Wells Fargo & Company | 0.01% | Add +14.9% | 43,457 | $25.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -16.2% | 40,079 | $23.3M |
| Marshall Wace, LLP | 0.02% | Add +5554.0% | 39,578 | $23.0M |
| Emerald Advisers, LLC | 0.70% | Reduce -23.3% | 38,913 | $22.7M |
| Barclays PLC | 0.01% | Reduce -22.4% | 38,720 | $22.5M |
| Citadel Advisors | 0.01% | Reduce -25.3% | 36,134 | $21.0M |
| Atika Capital Management LLC | 2.76% | New | 34,000 | $19.8M |
| Segall Bryant & Hamill, LLC | 0.26% | Add +49.0% | 33,520 | $19.5M |
| Gilder Gagnon Howe & Co. LLC | 0.21% | Add +8.5% | 33,468 | $19.5M |
| Public Sector Pension Investment Board | 0.06% | New | 32,871 | $19.1M |
| California Public Employees Retirement System | 0.01% | Add +29.8% | 31,286 | $18.2M |
| Affinity Asset Advisors, LLC | 1.34% | Reduce -72.9% | 31,131 | $18.1M |
| Groupama Asset Managment | 0.26% | Add +11.6% | 30,620 | $17.8M |
| Ameriprise Financial Inc. | 0.00% | Add +125.3% | 29,287 | $17.1M |
| Schroder Investment Management Group | 0.01% | Add +74.9% | 29,051 | $17.0M |
| Swiss National Bank | 0.01% | Add +2.4% | 28,580 | $16.6M |
| Steadfast Capital Management LP | 0.27% | Reduce -9.9% | 26,850 | $15.6M |
| Rheos Capital Works Inc. | 0.98% | Reduce -39.3% | 26,215 | $15.3M |
| Emerald Mutual Fund Advisers Trust | 0.71% | Reduce -28.8% | 24,996 | $14.6M |
| First Trust Advisors LP | 0.01% | Add +554.0% | 24,819 | $14.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +1.6% | 23,846 | $13.9M |
| Rhumbline Advisers | 0.01% | Reduce -13.1% | 23,691 | $13.8M |
| Citigroup Inc. | 0.01% | Add +141.8% | 23,327 | $13.6M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -73.8% | 23,226 | $13.5M |
| Sei Investments Co. | 0.01% | Add +20.7% | 23,076 | $13.4M |
| Alliancebernstein L.P. | 0.00% | Reduce -38.6% | 21,912 | $12.8M |
| Tao Capital Management LP | 10.53% | Reduce -48.8% | 21,000 | $12.2M |
| Rockefeller Capital Management L.P. | 0.02% | Add +6.6% | 19,661 | $11.4M |
| Rhenman & Partners Asset Management AB | 1.06% | Add +7.1% | 19,550 | $11.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +233.2% | 19,321 | $11.3M |
| Jump Financial, LLC | 0.15% | Reduce -8.3% | 19,221 | $11.2M |
| Bridgewater Associates | 0.04% | Reduce -30.8% | 19,218 | $11.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +24.8% | 19,076 | $11.1M |
| Neuberger Berman Group LLC | 0.01% | Add +0.7% | 18,660 | $10.9M |
| Stempoint Capital LP | 1.77% | Add +116.1% | 17,736 | $10.3M |
| WCM Investment Management, LLC | 0.02% | Reduce -5.7% | 17,254 | $10.1M |
| LPL Financial LLC | 0.00% | Reduce -26.6% | 16,542 | $9.6M |
| Federated Hermes, Inc. | 0.02% | Add +320.2% | 16,325 | $9.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -7.4% | 16,052 | $9.4M |
| Envestnet Asset Management Inc. | 0.00% | Add +5.5% | 15,372 | $9.0M |
"% of holder's portfolio" is MDGL's weight in each manager's 13F, not the share of Madrigal Pharmaceuticals Inc. the manager owns.