Madrigal PharmaceuticalsMDGL
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 387 institutions reported holding Madrigal Pharmaceuticals Inc. (MDGL) in their 13F filings, up 35 from Q3 2025. 71 opened new positions and 39 sold out. The largest holders were Baker Bros. Advisors LP ($1.2B), RTW Investments, LP ($1.2B) and Vanguard Group Inc. ($1.1B). 10 famous investors held it, including John Paulson (30.5% of Paulson & Co.'s portfolio), Steve Cohen (0.1% of Point72 Asset Management's portfolio) and Jim Simons / Peter Brown (0.1% of Renaissance Technologies's portfolio).
- Company
- Madrigal Pharmaceuticals Inc.
- CUSIP
- 558868105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 71 | $131.2M |
| Exits | 39 | $138.8M |
All 13F filers, Q3 2025 → Q4 2025: 1,939,328 shares bought and 1,931,422 shares sold, net +7,906 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 387 holders
| Baker Bros. Advisors LP | 7.33% | No change | 2,141,701 | $1.2B |
| RTW Investments, LP | 11.63% | No change | 1,993,687 | $1.2B |
| Vanguard Group Inc. | 0.02% | Reduce -0.2% | 1,808,894 | $1.1B |
| Avoro Capital Advisors LLC | 10.35% | Reduce -1.4% | 1,807,500 | $1.1B |
| Paulson & Co. | 30.48% | Reduce -10.5% | 1,707,522 | $994.4M |
| BlackRock, Inc. | 0.02% | Add +5.5% | 1,644,750 | $957.8M |
| Janus Henderson Group PLC | 0.41% | Reduce -14.0% | 1,584,843 | $918.2M |
| State Street Corp. | 0.01% | Reduce -11.4% | 583,003 | $339.5M |
| Wellington Management Group LLP | 0.05% | Add +14.1% | 461,402 | $268.7M |
| Geode Capital Management, LLC | 0.02% | Add +1.2% | 451,743 | $263.1M |
| FMR LLC | 0.01% | Add +9.5% | 439,398 | $255.9M |
| Bank of America Corp. | 0.02% | Add +70.3% | 416,025 | $242.3M |
| Invesco Ltd. | 0.02% | Add +21.9% | 365,314 | $212.7M |
| William Blair Investment Management, LLC | 0.58% | Reduce -14.0% | 354,220 | $206.3M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -11.0% | 313,659 | $182.7M |
| Goldman Sachs Group Inc. | 0.03% | Reduce -20.8% | 305,847 | $178.1M |
| Polar Capital Holdings Plc | 0.72% | Add +1.9% | 270,151 | $157.3M |
| Armistice Capital, LLC | 3.79% | Add +121.5% | 265,705 | $154.7M |
| Hood River Capital Management LLC | 1.58% | Add +2.0% | 247,560 | $144.2M |
| Lord, Abbett & Co. LLC | 0.46% | Add +139.7% | 244,796 | $142.6M |
| Alkeon Capital Management LLC | 0.61% | Add +100.0% | 240,000 | $139.8M |
| Charles Schwab Investment Management Inc. | 0.02% | Add +2.5% | 219,099 | $127.6M |
| Artisan Partners Limited Partnership | 0.18% | Reduce -3.7% | 198,693 | $115.7M |
| Norges Bank | 0.01% | — | 196,393 | $114.4M |
| Deutsche Bank AG | 0.04% | Add +414.5% | 192,109 | $111.9M |
| American Century Companies Inc. | 0.05% | Add +11.8% | 185,116 | $107.8M |
| Pictet Asset Management Holding SA | 0.10% | Reduce -5.1% | 181,949 | $106.0M |
| Fiera Capital Corp | 0.31% | Add +32.6% | 169,456 | $98.7M |
| Northern Trust Corp. | 0.01% | Reduce -5.1% | 151,802 | $88.4M |
| Morgan Stanley | 0.01% | Reduce -39.7% | 150,462 | $87.6M |
| Erste Asset Management GmbH | 0.69% | Reduce -29.8% | 141,100 | $82.3M |
| Rock Springs Capital Management LP | 4.19% | Add +1.4% | 139,618 | $81.3M |
| Bank of New York Mellon Corp | 0.01% | Add +40.0% | 136,869 | $79.7M |
| Point72 Asset Management | 0.12% | Add +206.6% | 126,435 | $73.6M |
| Woodline Partners LP | 0.28% | Add +21.0% | 125,659 | $73.2M |
| Nuveen, LLC | 0.02% | Add +60.6% | 118,363 | $68.9M |
| Driehaus Capital Management LLC | 0.44% | Reduce -3.7% | 111,666 | $65.0M |
| UBS Group AG | 0.01% | Reduce -52.8% | 102,641 | $59.8M |
| MPM Bioimpact LLC | 6.45% | Reduce -3.6% | 96,780 | $56.4M |
| Jane Street Group, LLC | 0.07% | Reduce -2.7% | 93,114 | $54.2M |
| D. E. Shaw & Co. | 0.04% | Reduce -7.9% | 88,554 | $51.6M |
| Franklin Resources Inc. | 0.01% | Add +13.9% | 86,076 | $50.1M |
| Tri Locum Partners LP | 6.50% | Add +27.1% | 86,023 | $50.1M |
| Renaissance Technologies | 0.08% | Reduce -30.5% | 83,862 | $48.8M |
| ArrowMark Colorado Holdings LLC | 1.06% | Reduce -33.0% | 82,624 | $48.1M |
| New York State Common Retirement Fund | 0.06% | Add +9.6% | 75,933 | $44.2M |
| Squarepoint Ops LLC | 0.09% | Add +150.3% | 74,934 | $43.6M |
| BNP Paribas Financial Markets | 0.03% | Add +4.2% | 73,707 | $42.9M |
| First Light Asset Management, LLC | 2.98% | Add +479.2% | 66,831 | $38.9M |
| Raymond James Financial Inc. | 0.01% | Reduce -5.5% | 66,724 | $38.9M |
| Susquehanna International Group, LLP | 0.05% | Reduce -38.5% | 64,466 | $37.5M |
| Voya Investment Management LLC | 0.04% | Add +8.1% | 64,254 | $37.4M |
| Candriam S.C.A. | 0.19% | Add +27.9% | 63,906 | $37.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.09% | Reduce -32.0% | 58,295 | $33.9M |
| Jain Global LLC | 0.31% | New | 52,721 | $30.7M |
| Ensign Peak Advisors, Inc | 0.05% | Reduce -4.2% | 51,010 | $29.7M |
| Mirae Asset Global Investments Co., Ltd. | 0.08% | Add +0.1% | 50,631 | $29.5M |
| EULAV Asset Management | 0.76% | Reduce -3.9% | 49,000 | $28.5M |
| Russell Investments Group, Ltd. | 0.03% | Add +7.3% | 48,159 | $28.0M |
| Canada Pension Plan Investment Board | 0.02% | Add +412.4% | 46,120 | $26.9M |
| Wells Fargo & Company | 0.01% | Add +14.9% | 43,457 | $25.3M |
| JPMorgan Chase & Co. | 0.00% | Reduce -16.2% | 40,079 | $23.3M |
| Marshall Wace, LLP | 0.02% | Add +5554.0% | 39,578 | $23.0M |
| Emerald Advisers, LLC | 0.70% | Reduce -23.3% | 38,913 | $22.7M |
| Barclays PLC | 0.01% | Reduce -22.4% | 38,720 | $22.5M |
| Citadel Advisors | 0.01% | Reduce -25.3% | 36,134 | $21.0M |
| Atika Capital Management LLC | 2.76% | New | 34,000 | $19.8M |
| Segall Bryant & Hamill, LLC | 0.26% | Add +49.0% | 33,520 | $19.5M |
| Gilder Gagnon Howe & Co. LLC | 0.21% | Add +8.5% | 33,468 | $19.5M |
| Public Sector Pension Investment Board | 0.06% | New | 32,871 | $19.1M |
| California Public Employees Retirement System | 0.01% | Add +29.8% | 31,286 | $18.2M |
| Affinity Asset Advisors, LLC | 1.34% | Reduce -72.9% | 31,131 | $18.1M |
| Groupama Asset Managment | 0.26% | Add +11.6% | 30,620 | $17.8M |
| Ameriprise Financial Inc. | 0.00% | Add +125.3% | 29,287 | $17.1M |
| Schroder Investment Management Group | 0.01% | Add +74.9% | 29,051 | $17.0M |
| Swiss National Bank | 0.01% | Add +2.4% | 28,580 | $16.6M |
| Steadfast Capital Management LP | 0.27% | Reduce -9.9% | 26,850 | $15.6M |
| Rheos Capital Works Inc. | 0.98% | Reduce -39.3% | 26,215 | $15.3M |
| Emerald Mutual Fund Advisers Trust | 0.71% | Reduce -28.8% | 24,996 | $14.6M |
| First Trust Advisors LP | 0.01% | Add +554.0% | 24,819 | $14.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +1.6% | 23,846 | $13.9M |
| Rhumbline Advisers | 0.01% | Reduce -13.1% | 23,691 | $13.8M |
| Citigroup Inc. | 0.01% | Add +141.8% | 23,327 | $13.6M |
| Adage Capital Partners Gp, L.L.C. | 0.02% | Reduce -73.8% | 23,226 | $13.5M |
| Sei Investments Co. | 0.01% | Add +20.7% | 23,076 | $13.4M |
| Alliancebernstein L.P. | 0.00% | Reduce -38.6% | 21,912 | $12.8M |
| Tao Capital Management LP | 10.53% | Reduce -48.8% | 21,000 | $12.2M |
| Rockefeller Capital Management L.P. | 0.02% | Add +6.6% | 19,661 | $11.4M |
| Rhenman & Partners Asset Management AB | 1.06% | Add +7.1% | 19,550 | $11.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +233.2% | 19,321 | $11.3M |
| Jump Financial, LLC | 0.15% | Reduce -8.3% | 19,221 | $11.2M |
| Bridgewater Associates | 0.04% | Reduce -30.8% | 19,218 | $11.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.02% | Add +24.8% | 19,076 | $11.1M |
| Neuberger Berman Group LLC | 0.01% | Add +0.7% | 18,660 | $10.9M |
| Stempoint Capital LP | 1.77% | Add +116.1% | 17,736 | $10.3M |
| WCM Investment Management, LLC | 0.02% | Reduce -5.7% | 17,254 | $10.1M |
| LPL Financial LLC | 0.00% | Reduce -26.6% | 16,542 | $9.6M |
| Federated Hermes, Inc. | 0.02% | Add +320.2% | 16,325 | $9.5M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -7.4% | 16,052 | $9.4M |
| Envestnet Asset Management Inc. | 0.00% | Add +5.5% | 15,372 | $9.0M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.01% | Add +11102.2% | 15,347 | $8.9M |
| Legal & General Group Plc | 0.00% | Reduce -29.7% | 15,231 | $8.9M |
| Man Group plc | 0.02% | Reduce -30.8% | 14,764 | $8.6M |
| Castleark Management LLC | 0.25% | Add +45.7% | 14,466 | $8.4M |
| California State Teachers Retirement System | 0.01% | Add +0.8% | 14,008 | $8.2M |
| Skandinaviska Enskilda Banken AB (publ) | 0.03% | Reduce -26.8% | 13,450 | $7.8M |
| Informed Momentum Co LLC | 0.83% | Add +18.4% | 12,837 | $7.5M |
| Journey Strategic Wealth LLC | 0.20% | Add +0.0% | 12,829 | $7.5M |
| Mutual of America Capital Management LLC | 0.07% | Reduce -0.7% | 12,100 | $7.0M |
| IMC-Chicago, LLC | 0.12% | New | 12,051 | $7.0M |
| Nan Fung Group Holdings Ltd | 6.19% | No change | 11,872 | $6.9M |
| Nomura Asset Management International Inc. | 0.01% | — | 11,592 | $6.8M |
| Voleon Capital Management LP | 0.14% | New | 11,235 | $6.5M |
| Creative Planning | 0.00% | Add +32.2% | 11,141 | $6.5M |
| Resolute Capital Asset Partners LLC | 3.07% | Reduce -27.2% | 10,918 | $6.4M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Reduce -7.0% | 10,561 | $6.2M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -43.7% | 10,530 | $6.1M |
| EFG International AG | 0.12% | — | 10,373 | $6.1M |
| TD Asset Management Inc | 0.00% | Reduce -22.1% | 10,386 | $6.0M |
| MetLife Investment Management, LLC | 0.03% | Reduce -5.3% | 10,237 | $6.0M |
| Royal Bank of Canada | 0.00% | Reduce -49.3% | 10,223 | $6.0M |
| AQR Capital Management | 0.00% | Add +51.9% | 10,006 | $5.8M |
| State of Wisconsin Investment Board | 0.01% | Reduce -14.7% | 9,276 | $5.4M |
| Algert Global LLC | 0.08% | Add +11.7% | 8,970 | $5.2M |
| Verition Fund Management LLC | 0.03% | Add +58.0% | 8,893 | $5.2M |
| Engineers Gate Manager LP | 0.06% | Add +196.8% | 8,708 | $5.1M |
| Hennion & Walsh Asset Management, Inc. | 0.16% | Reduce -36.5% | 8,163 | $4.8M |
| Trexquant Investment LP | 0.04% | New | 7,784 | $4.5M |
| Intech Investment Management LLC | 0.04% | Add +9.5% | 7,301 | $4.3M |
| Principal Financial Group Inc. | 0.00% | Reduce -39.8% | 7,261 | $4.2M |
| PFM Health Sciences, LP | 0.43% | New | 7,258 | $4.2M |
| Millennium Management | 0.00% | Add +288.1% | 6,978 | $4.1M |
| Entropy Technologies, LP | 0.22% | Add +87.5% | 6,942 | $4.0M |
| Capricorn Fund Managers Ltd | 0.93% | New | 6,600 | $3.8M |
| Calamos Advisors LLC | 0.02% | Add +46.4% | 6,566 | $3.8M |
| SG Americas Securities, LLC | 0.00% | Add +23.0% | 6,386 | $3.7M |
| Susquehanna Portfolio Strategies, LLC | 0.06% | No change | 6,250 | $3.6M |
| Victory Capital Management Inc. | 0.00% | Add +1.0% | 5,822 | $3.4M |
| F/m Investments LLC | 0.13% | Reduce -9.2% | 5,738 | $3.3M |
| Prudential Financial Inc. | 0.00% | Reduce -4.0% | 5,675 | $3.3M |
| Assenagon Asset Management S.A. | 0.00% | New | 5,390 | $3.1M |
| Orion Porfolio Solutions, LLC | 0.02% | Add +30.8% | 5,350 | $3.1M |
| Tudor Investment Corporation | 0.02% | Add +470.7% | 5,285 | $3.1M |
| Fieldview Capital Management, LLC | 0.51% | Add +11.6% | 5,196 | $3.0M |
| Handelsbanken Fonder AB | 0.01% | Add +15.4% | 5,080 | $3.0M |
| O'Neil Global Advisors, Inc. | 1.01% | New | 5,060 | $2.9M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -3.5% | 5,044 | $2.9M |
| Police & Firemen's Retirement System of New Jersey | 0.02% | Reduce -2.9% | 5,016 | $2.9M |
| Assetmark, Inc. | 0.01% | Reduce -4.9% | 4,810 | $2.8M |
| State Board of Administration of Florida Retirement System | 0.00% | Add +3.3% | 4,759 | $2.8M |
| Pathstone Holdings, LLC | 0.01% | Add +94.3% | 4,733 | $2.8M |
| Peak Financial Advisors LLC | 1.17% | Add +287.0% | 4,466 | $2.6M |
| ProShare Advisors LLC | 0.00% | Add +11.9% | 4,449 | $2.6M |
| HRT Financial LP | 0.01% | New | 4,218 | $2.5M |
| Profund Advisors LLC | 0.07% | Reduce -1.1% | 4,157 | $2.4M |
| Los Angeles Capital Management LLC | 0.01% | Add +9.3% | 5,603 | $2.4M |
| Arizona State Retirement System | 0.01% | Reduce -5.0% | 4,040 | $2.4M |
| Shikiar Asset Management Inc. | 0.63% | No change | 4,000 | $2.3M |
| Acadian Asset Management LLC | 0.00% | New | 3,958 | $2.3M |
| Cetera Investment Advisers | 0.00% | Add +5.8% | 3,941 | $2.3M |
| Moody Aldrich Partners LLC | 0.42% | New | 3,876 | $2.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 8,000 | $2.3M |
| Knights of Columbus Asset Advisors LLC | 0.12% | Reduce -3.8% | 3,702 | $2.2M |
| China Universal Asset Management Co., Ltd. | 0.17% | Reduce -5.3% | 3,701 | $2.2M |
| Cinctive Capital Management LP | 0.12% | Add +2.3% | 3,687 | $2.1M |
| Brevan Howard Capital Management LP | 0.04% | Add +164.2% | 3,632 | $2.1M |
| Allworth Financial LP | 0.01% | Add +0.3% | 3,558 | $2.1M |
| NFSG Corp | 0.32% | Reduce -2.6% | 3,548 | $2.1M |
| Martingale Asset Management L P | 0.05% | Reduce -25.0% | 3,386 | $2.0M |
| Farallon Capital Management, L.L.C. | 0.01% | No change | 3,319 | $1.9M |
| Sphera Funds Management LTD. | 0.40% | New | 3,300 | $1.9M |
| STRS Ohio | 0.01% | Add +50.0% | 3,300 | $1.9M |
| KLP Kapitalforvaltning As | 0.01% | Add +8.0% | 3,240 | $1.9M |
| Osaic Holdings, Inc. | 0.00% | Add +280.3% | 3,050 | $1.8M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +40.3% | 2,978 | $1.7M |
| Penn Capital Management Company, LLC | 0.14% | New | 2,902 | $1.7M |
| Bellevue Group AG | 0.03% | Add +20.5% | 2,884 | $1.7M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 2,872 | $1.7M |
| Dana Investment Advisors, Inc. | 0.05% | Reduce -9.9% | 2,866 | $1.7M |
| HighVista Strategies LLC | 0.43% | Reduce -19.7% | 2,839 | $1.7M |
| XTX Topco Ltd | 0.04% | New | 2,819 | $1.6M |
| Ami Asset Management Corp. | 0.09% | Reduce -19.7% | 2,752 | $1.6M |
| Aigen Investment Management, LP | 0.36% | Add +353.3% | 2,652 | $1.5M |
| Quadrant Capital Group LLC | 0.05% | No change | 2,605 | $1.5M |
| Strid Group, LLC | 0.18% | No change | 2,500 | $1.5M |
| Baron Capital (BAMCO) | 0.00% | Reduce -3.9% | 2,500 | $1.5M |
| Mariner, LLC | 0.00% | Add +33.2% | 2,426 | $1.4M |
| Allianz Asset Management GmbH | 0.00% | Reduce -22.6% | 2,400 | $1.4M |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -5.5% | 2,342 | $1.4M |
| Stifel Financial Corp. | 0.00% | Reduce -10.8% | 2,327 | $1.4M |
| Jefferies Financial Group Inc. | 0.01% | New | 2,300 | $1.3M |
| Inspire Investing, LLC | 0.12% | New | 2,256 | $1.3M |
| Snowden Capital Advisors LLC | 0.03% | Reduce -11.3% | 2,225 | $1.3M |
| Guggenheim Capital LLC | 0.01% | Add +33.0% | 2,161 | $1.3M |
| Teacher Retirement System of Texas | 0.00% | Reduce -39.1% | 2,151 | $1.3M |
| D.A. Davidson & Co. | 0.01% | Add +2.8% | 2,129 | $1.2M |
| Knott David M Jr | 0.54% | No change | 2,000 | $1.2M |
| Toth Financial Advisory Corp. | 0.13% | New | 2,000 | $1.2M |
| FORA Capital, LLC | 0.14% | Reduce -20.2% | 1,997 | $1.2M |
| Illinois Municipal Retirement Fund | 0.01% | New | 1,903 | $1.1M |
| Cwm, LLC | 0.00% | Reduce -20.6% | 1,875 | $1.1M |
| Seven Fleet Capital Management LP | 0.73% | — | 1,860 | $1.1M |
| MML Investors Services, LLC | 0.00% | Add +20.0% | 1,668 | $971K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 1,608 | $937K |
| Kestra Advisory Services, LLC | 0.00% | Add +0.8% | 1,580 | $920K |
| Tema ETFs LLC | 0.07% | Reduce -3.1% | 1,571 | $915K |
| NEOS Investment Management LLC | 0.01% | Reduce -3.1% | 1,571 | $915K |
| J. Safra Sarasin Holding AG | 0.01% | Reduce -35.5% | 1,546 | $900K |
| Ameritas Investment Partners, Inc. | 0.03% | Reduce -1.2% | 1,536 | $894K |
| AlTi Global, Inc. | 0.02% | Add +0.1% | 1,493 | $869K |
| Xponance LLC | 0.01% | Add +0.2% | 1,463 | $852K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +113.7% | 1,513 | $844K |
| Cerity Partners LLC | 0.00% | Add +50.0% | 1,444 | $841K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 1,433 | $834K |
| New York Life Investment Management LLC | 0.01% | Reduce -13.9% | 1,386 | $807K |
| Sanctuary Advisors, LLC | 0.00% | Reduce -6.4% | 1,371 | $798K |
| Two Sigma Securities, LLC | 0.11% | New | 1,336 | $778K |
| Oppenheimer Asset Management Inc. | 0.01% | Add +18.7% | 1,313 | $765K |
| O'shaughnessy Asset Management, LLC | 0.00% | Add +49.9% | 1,283 | $747K |
| Vanguard Personalized Indexing Management, LLC | 0.01% | Add +14.7% | 1,249 | $727K |
| Federation des caisses Desjardins du Quebec | 0.00% | Add +14.9% | 1,246 | $726K |
| Cibc World Markets Corp. | 0.00% | — | 1,231 | $717K |
| B. Metzler seel. Sohn & Co. AG | 0.01% | No change | 1,221 | $711K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -5.7% | 1,198 | $698K |
| Virtus Investment Advisers, LLC | 0.19% | Reduce -20.1% | 1,194 | $695K |
| HighTower Advisors, LLC | 0.00% | Add +4.1% | 1,173 | $683K |
| Everhart Financial Group, Inc. | 0.06% | Add +153.4% | 1,163 | $677K |
| Verity Asset Management, Inc. | 0.29% | Reduce -8.1% | 1,158 | $674K |
| Captrust Financial Advisors | 0.00% | Add +99.8% | 1,131 | $659K |
| HSBC Holdings PLC | 0.00% | New | 1,100 | $646K |
| Landscape Capital Management, L.L.C. | 0.04% | Add +7.7% | 1,088 | $634K |
| Pier 88 Investment Partners LLC | 0.72% | New | 1,080 | $629K |
| Graham Capital Management, L.P. | 0.03% | New | 1,062 | $618K |
| Natixis | 0.00% | New | 1,041 | $606K |
| Cynosure Group, LLC | 0.06% | New | 1,025 | $597K |
| Blair William & Co. | 0.00% | No change | 1,000 | $582K |
| Optimize Financial Inc. | 0.29% | Add +1.2% | 992 | $578K |
| Atria Investments, Inc | 0.01% | Reduce -2.2% | 988 | $575K |
| Syon Capital LLC | 0.03% | No change | 965 | $562K |
| Baader Bank Aktiengesellschaft | 0.04% | Reduce -53.4% | 902 | $525K |
| ADAR1 Capital Management, LLC | 0.04% | Reduce -81.7% | 895 | $521K |
| PSP Research LLC | 0.45% | — | 892 | $519K |
| Park Avenue Securities LLC | 0.00% | Add +9.2% | 858 | $499K |
| Intrust Bank NA | 0.04% | Add +25.8% | 848 | $494K |
| IFG Advisory, LLC | 0.02% | New | 844 | $491K |
| QRG Capital Management, Inc. | 0.01% | Add +8.2% | 834 | $486K |
| Elevation Point Wealth Partners, LLC | 0.02% | New | 824 | $480K |
| CIBC Asset Management Inc | 0.00% | Add +30.4% | 816 | $475K |
| PharVision Advisers, LLC | 0.24% | Add +39.7% | 813 | $473K |
| Vestmark Advisory Solutions, Inc. | 0.01% | New | 806 | $469K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | New | 800 | $466K |
| Chicago Partners Investment Group LLC | 0.01% | Reduce -6.2% | 961 | $462K |
| Vise Technologies, Inc. | 0.01% | New | 769 | $448K |
| Dorsey & Whitney Trust CO LLC | 0.02% | No change | 752 | $438K |
| Comerica Bank | 0.00% | Reduce -2.1% | 743 | $433K |
| Eurizon Capital SGR S.p.A. | 0.00% | — | 729 | $425K |
| Abel Hall, LLC | 0.10% | Add +20.3% | 710 | $413K |
| Centaurus Financial, Inc. | 0.02% | No change | 709 | $413K |
| Composition Wealth, LLC | 0.01% | No change | 703 | $409K |
| Cannon Global Investment Management, LLC | 1.09% | Reduce -12.5% | 700 | $408K |
| Glenmede Trust Co. NA | 0.00% | — | 691 | $402K |
| Swiss Life Asset Management Ltd | 0.00% | Add +6.8% | 690 | $402K |
| Advisory Services Network, LLC | 0.01% | New | 658 | $383K |
| Allspring Global Investments Holdings, LLC | 0.00% | New | 631 | $375K |
| M&T Bank Corp | 0.00% | New | 629 | $366K |
| Cary Street Partners Financial LLC | 0.01% | New | 628 | $366K |
| JGP Global Gestao de Recursos Ltda. | 0.22% | Reduce -40.0% | 625 | $364K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +71.4% | 612 | $356K |
| EP Wealth Advisors, LLC | 0.00% | — | 609 | $355K |
| Amalgamated Bank | 0.00% | Reduce -3.1% | 584 | $340K |
| Truist Financial Corp. | 0.00% | Reduce -5.6% | 569 | $331K |
| Integrated Investment Consultants, LLC | 0.06% | No change | 567 | $330K |
| Praxis Investment Management Inc. | 0.02% | No change | 540 | $314K |
| Private Advisor Group, LLC | 0.00% | New | 536 | $312K |
| James J. Burns & Company, LLC | 0.04% | New | 532 | $310K |
| OneDigital Investment Advisors LLC | 0.00% | Reduce -15.8% | 519 | $302K |
| TCI Wealth Advisors, Inc. | 0.02% | No change | 517 | $301K |
| &partners | 0.00% | New | 509 | $296K |
| Soleus Capital Management, L.P. | 0.01% | Reduce -99.3% | 500 | $291K |
| IFP Advisors, Inc | 0.01% | Add +24.3% | 461 | $268K |
| Kestra Investment Management, LLC | 0.01% | Add +0.7% | 445 | $259K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -7.3% | 445 | $259K |
| US Bancorp \de | 0.00% | Add +13.7% | 441 | $257K |
| Amundi | 0.00% | New | 437 | $254K |
| SummitTX Capital, L.P. | 0.01% | New | 433 | $252K |
| Brooklyn Investment Group | 0.01% | New | 427 | $252K |
| Prelude Capital Management, LLC | 0.02% | New | 430 | $250K |
| Loring Wolcott & Coolidge Fiduciary Advisors LLP | 0.00% | No change | 500 | $250K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -1.4% | 429 | $250K |
| Ethic Inc. | 0.00% | New | 426 | $248K |
| AlphaQuest LLC | 0.01% | Add +707.7% | 420 | $245K |
| WASHINGTON TRUST Co | 0.01% | New | 420 | $245K |
| KBC Group NV | 0.00% | No change | 414 | $241K |
| Bridgefront Capital, LLC | 0.06% | Reduce -45.1% | 393 | $229K |
| Oppenheimer & Co. Inc. | 0.00% | New | 392 | $228K |
| Choreo, LLC | 0.00% | New | 381 | $222K |
| Kozak & Associates, Inc. | 0.04% | No change | 424 | $218K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.03% | Reduce -53.2% | 371 | $216K |
| Callan Family Office, LLC | 0.00% | New | 366 | $213K |
| Quantinno Capital Management LP | 0.00% | New | 364 | $212K |
| Virtus Advisers, LLC | 0.10% | New | 360 | $210K |
| Sectoral Asset Management Inc. | 0.16% | Reduce -51.8% | 352 | $205K |
| Destination Wealth Management | 0.01% | New | 350 | $204K |
| Covestor Ltd | 0.09% | Add +653.7% | 309 | $180K |
| PNC Financial Services Group, Inc. | 0.00% | Add +5.7% | 277 | $161K |
| Parallel Advisors, LLC | 0.00% | Reduce -3.1% | 251 | $146K |
| Pinnacle Wealth Planning Services, Inc. | 0.01% | New | 233 | $136K |
| UMB Bank, n.a. | 0.00% | No change | 230 | $134K |
| Walleye Trading LLC | 0.00% | New | 214 | $125K |
| Danske Bank A/S | 0.00% | New | 200 | $116K |
| Jones Financial Companies LLLP | 0.00% | No change | 199 | $116K |
| Montag A & Associates Inc. | 0.01% | No change | 194 | $113K |
| Smartleaf Asset Management LLC | 0.00% | Add +50.8% | 187 | $109K |
| Valley National Advisers Inc. | 0.01% | Add +312.8% | 161 | $93K |
| Torren Management, LLC | 0.05% | — | 155 | $90K |
| Farther Finance Advisors, LLC | 0.00% | Add +34.6% | 140 | $82K |
| GAMMA Investing LLC | 0.00% | Add +53.3% | 138 | $80K |
| Sterling Capital Management LLC | 0.00% | Add +171.1% | 122 | $71K |
| Signaturefd, LLC | 0.00% | No change | 115 | $67K |
| SageView Advisory Group, LLC | 0.00% | New | 112 | $65K |
| Accent Capital Management, LLC | 0.02% | Add +64.9% | 94 | $55K |
| Eastern Bank | 0.00% | Add +32.3% | 86 | $50K |
| CoreCap Advisors, LLC | 0.00% | Add +20.6% | 82 | $48K |
| Global Retirement Partners, LLC | 0.00% | Add +10.8% | 82 | $48K |
| PEAK6 LLC | 0.00% | New | 77 | $45K |
| Walleye Capital LLC | 0.00% | New | 69 | $40K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -2.9% | 68 | $40K |
| First Horizon Corp. | 0.00% | Reduce -9.3% | 68 | $40K |
| Optiver Holding B.V. | 0.00% | Reduce -50.0% | 68 | $40K |
| Kemnay Advisory Services Inc. | 0.01% | New | 67 | $39K |
| MAI Capital Management | 0.00% | Add +1016.7% | 67 | $39K |
| Aventura Private Wealth, LLC | 0.01% | No change | 62 | $36K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -16.4% | 61 | $36K |
| Quarry LP | 0.01% | Reduce -36.0% | 55 | $32K |
| McIlrath & Eck, LLC | 0.00% | No change | 52 | $30K |
| CIBC Private Wealth Group LLC | 0.00% | Add +2.0% | 52 | $30K |
| Flagship Harbor Advisors, LLC | 0.00% | New | 50 | $29K |
| Lanark Financial, Inc. | 0.00% | No change | 48 | $28K |
| Basecamp Wealth Advisors LLC | 0.01% | — | 43 | $25K |
| City Holding Co. | 0.00% | New | 40 | $23K |
| Quattro Advisors LLC | 0.01% | — | 31 | $18K |
| Rakuten Securities, Inc. | 0.01% | No change | 30 | $17K |
| Leonteq Securities AG | 0.00% | Reduce -48.2% | 29 | $17K |
| Huntington National Bank | 0.00% | Reduce -3.3% | 29 | $17K |
| Bradley & Co. Private Wealth Management, LLC | 0.01% | No change | 27 | $16K |
| Arax Advisory Partners | 0.00% | Add +80.0% | 27 | $16K |
| Bessemer Group Inc. | 0.00% | Add +380.0% | 24 | $14K |
| Rothschild Investment LLC | 0.00% | No change | 24 | $14K |
| Compagnie Lombard Odier SCmA | 0.00% | Reduce -76.9% | 24 | $14K |
| Contravisory Investment Management, Inc. | 0.00% | New | 23 | $13K |
| MV Capital Management, Inc. | 0.00% | No change | 22 | $13K |
| Sound Income Strategies, LLC | 0.00% | New | 25 | $13K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +75.0% | 21 | $12K |
| Larson Financial Group LLC | 0.00% | Add +13.3% | 17 | $10K |
| Harbor Investment Advisory, LLC | 0.00% | New | 14 | $8K |
| Vermillion & White Wealth Management Group, LLC | 0.00% | No change | 14 | $8K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Reduce -87.1% | 11 | $6K |
| Motiv8 Investments LLC | 0.00% | New | 10 | $6K |
| Parkside Financial Bank & Trust | 0.00% | No change | 10 | $6K |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 10 | $6K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 10 | $6K |
| Cape Investment Advisory, Inc. | 0.00% | No change | 9 | $5K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 9 | $5K |
| Bell Investment Advisors, Inc | 0.00% | Add +60.0% | 8 | $5K |
| Signature Resources Capital Management, LLC | 0.00% | No change | 7 | $4K |
| Meeder Asset Management Inc. | 0.00% | No change | 7 | $4K |
| Webster Bank, N. A. | 0.00% | No change | 6 | $3K |
| Zions Bancorporation, National Association | 0.00% | New | 5 | $3K |
| Brown Brothers Harriman & Co. | 0.00% | No change | 5 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +25.0% | 5 | $3K |
| Retirement Wealth Solutions LLC | 0.00% | No change | 4 | $2K |
| Atlantic Union Bankshares Corp | 0.00% | New | 4 | $2K |
| Cornerstone Financial Management LLC | 0.00% | — | 4 | $2K |
| Cary Street Partners Investment Advisory LLC | 0.00% | New | 4 | $2K |
| Park Place Capital Corp | 0.00% | No change | 4 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | Add +200.0% | 3 | $2K |
| Caitlin John, LLC | 0.00% | No change | 2 | $1K |
| Hughes Financial Services, LLC | 0.00% | New | 2 | $1K |
| SouthState Bank Corp | 0.00% | No change | 2 | $1K |
| CX Institutional | 0.00% | New | 2 | $1K |
| Rachor Investment Advisory Services, LLC | 0.00% | — | 1 | $583 |
| Marquette Asset Management, LLC | 0.00% | Reduce -66.7% | 1 | $583 |
| SJS Investment Consulting Inc. | 0.00% | New | 1 | $583 |
| TD Capital Management LLC | 0.00% | No change | 1 | $582 |
| Fortitude Family Office, LLC | 0.00% | No change | 1 | $582 |
| Bogart Wealth, LLC | 0.00% | No change | 1 | $582 |
| Avion Wealth | 0.00% | New | 1 | $0 |
"% of holder's portfolio" is MDGL's weight in each manager's 13F, not the share of Madrigal Pharmaceuticals Inc. the manager owns.