Mineralys TherapeuticsMLYS
13F holders, Q1 2026 (March 31)215holders −8
25new positions
36sold out
7famous investors
$27.18avg. 13F price*
At the end of Q1 2026, 215 institutions reported holding Mineralys Therapeutics Inc. (MLYS) in their 13F filings, down 8 from Q4 2025. 25 opened new positions and 36 sold out. The largest holders were Catalys Pacific, LLC ($214.1M), Ra Capital Management, L.P. ($208.4M) and Samsara Biocapital, LLC ($159.0M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Mineralys Therapeutics Inc.
- CUSIP
- 603170101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 25 | $39.7M |
| Exits | 36 | $237.7M |
All 13F filers, Q4 2025 → Q1 2026: 13,988,579 shares bought and 11,700,414 shares sold, net +2,288,165 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 215 holders
| Catalys Pacific, LLC | 92.81% | No change | 7,903,838 | $214.1M |
| Ra Capital Management, L.P. | 2.21% | Add +5.0% | 7,692,750 | $208.4M |
| Samsara Biocapital, LLC | 15.45% | No change | 5,871,018 | $159.0M |
| FMR LLC | 0.01% | Reduce -3.9% | 4,861,104 | $131.7M |
| BlackRock, Inc. | 0.00% | Add +3.6% | 4,481,582 | $121.4M |
| Wellington Management Group LLP | 0.02% | Add +328.3% | 3,359,068 | $91.0M |
| State Street Corp. | 0.00% | Reduce -7.8% | 2,935,940 | $79.5M |
| Caligan Partners LP | 5.31% | No change | 2,772,654 | $75.1M |
| Vanguard Capital Management LLC | 0.00% | — | 2,454,363 | $66.5M |
| Laurion Capital Management LP | 5.98% | Add +30.3% | 2,232,040 | $60.5M |
| Orbimed Advisors LLC | 1.26% | Add +109.4% | 2,052,900 | $55.6M |
| Point72 Asset Management | 0.09% | Add +58.3% | 1,911,433 | $51.8M |
| Franklin Resources Inc. | 0.01% | Reduce -0.2% | 1,784,662 | $48.3M |
| Andera Partners | 24.38% | No change | 1,591,917 | $43.1M |
| SR One Capital Management, LP | 4.63% | No change | 1,563,966 | $42.4M |
| Montanova Capital, LLC | 1.13% | No change | 1,538,662 | $41.7M |
| Polar Capital Holdings Plc | 0.18% | Add +7.1% | 1,500,749 | $40.7M |
| T. Rowe Price Associates Inc. | 0.00% | Add +1.4% | 1,343,313 | $36.4M |
| Sphera Funds Management LTD. | 6.24% | Add +198.4% | 1,339,971 | $36.3M |
| Alliancebernstein L.P. | 0.01% | Add +5.8% | 975,961 | $35.4M |
| Geode Capital Management, LLC | 0.00% | Add +3.5% | 1,301,135 | $35.3M |
| Jennison Associates LLC | 0.02% | Add +0.6% | 1,266,174 | $34.3M |
| Armistice Capital, LLC | 1.05% | Add +74.0% | 1,176,000 | $31.9M |
| Bank of America Corp. | 0.00% | Add +11.4% | 1,100,372 | $29.8M |
| Pictet Asset Management Holding SA | 0.03% | Add +21.3% | 1,034,438 | $28.0M |
| Boothbay Fund Management, LLC | 0.65% | Add +1.0% | 1,001,728 | $27.1M |
| Qube Research & Technologies Ltd | 0.04% | Add +84.2% | 914,728 | $24.8M |
| Nantahala Capital Management, LLC | 1.52% | Add +690.5% | 895,481 | $24.3M |
| D. E. Shaw & Co. | 0.02% | Reduce -22.9% | 887,192 | $24.0M |
| American Century Companies Inc. | 0.01% | Reduce -2.6% | 884,107 | $24.0M |
| Morgan Stanley | 0.00% | Add +32.8% | 849,184 | $23.0M |
| Candriam S.C.A. | 0.11% | Add +18.2% | 801,904 | $21.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -45.9% | 785,043 | $21.3M |
| Affinity Asset Advisors, LLC | 1.22% | Add +2.7% | 750,000 | $20.3M |
| Integral Health Asset Management, LLC | 1.08% | No change | 750,000 | $20.3M |
| Vanguard Portfolio Management LLC | 0.00% | — | 706,658 | $19.1M |
| Troluce Capital Advisors LLC | 1.92% | New | 655,000 | $17.7M |
| Citadel Advisors | 0.01% | Add +50.0% | 600,041 | $16.3M |
| Stempoint Capital LP | 2.78% | Add +83.9% | 533,378 | $14.4M |
| Millennium Management | 0.01% | Add +568.1% | 525,260 | $14.2M |
| Davern Capital Partners, LP | 3.32% | Add +112.3% | 447,153 | $12.1M |
| 22NW, LP | 8.25% | Add +24.0% | 444,325 | $12.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.8% | 443,898 | $12.0M |
| Northern Trust Corp. | 0.00% | Add +47.7% | 442,874 | $12.0M |
| Rock Springs Capital Management LP | 0.70% | Add +2.8% | 439,751 | $11.9M |
| Catalio Capital Management, LP | 2.48% | Add +32.3% | 439,041 | $11.9M |
| Capital World Investors | 0.00% | New | 398,179 | $10.8M |
| Renaissance Technologies | 0.02% | Add +18.9% | 382,800 | $10.4M |
| Parkman Healthcare Partners LLC | 1.07% | Reduce -7.3% | 380,137 | $10.3M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 375,262 | $10.2M |
| Pale Fire Capital SE | 0.87% | Add +3431.3% | 365,626 | $9.9M |
| TimesSquare Capital Management, LLC | 0.16% | Reduce -10.9% | 338,798 | $9.2M |
| Two Sigma Investments, LP | 0.01% | Reduce -49.0% | 311,488 | $8.4M |
| Lord, Abbett & Co. LLC | 0.03% | Reduce -3.7% | 300,913 | $8.2M |
| Rhenman & Partners Asset Management AB | 0.88% | Add +84.5% | 263,071 | $7.1M |
| Algert Global LLC | 0.11% | Add +447.9% | 260,264 | $7.1M |
| SG Americas Securities, LLC | 0.01% | Reduce -2.1% | 225,833 | $6.1M |
| Ameriprise Financial Inc. | 0.00% | Add +378.5% | 221,305 | $6.0M |
| Voya Investment Management LLC | 0.01% | Add +91.8% | 216,089 | $5.9M |
| Russell Investments Group, Ltd. | 0.01% | Add +16.1% | 203,504 | $5.5M |
| Findell Capital Management LLC | 1.61% | Add +304.0% | 202,000 | $5.5M |
| Schonfeld Strategic Advisors LLC | 0.04% | Add +256.4% | 177,585 | $4.8M |
| Buckley Capital Advisors, LLC | 3.97% | Reduce -0.7% | 173,100 | $4.7M |
| Tudor Investment Corporation | 0.02% | Add +298.9% | 155,740 | $4.2M |
| ADAR1 Capital Management, LLC | 0.25% | Add +13.6% | 154,686 | $4.2M |
| Burkehill Global Management, LP | 0.21% | No change | 150,000 | $4.1M |
| AQR Capital Management | 0.00% | Add +139.3% | 149,086 | $4.0M |
| Mark Asset Management LP | 0.52% | New | 144,875 | $3.9M |
| PFM Health Sciences, LP | 0.41% | Add +199.5% | 142,677 | $3.9M |
| Artia Global Partners LP | 0.84% | No change | 137,800 | $3.7M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -0.1% | 137,433 | $3.7M |
| Y-Intercept (Hong Kong) Ltd | 0.07% | Add +321.3% | 132,099 | $3.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.4% | 129,964 | $3.5M |
| Swedbank AB | 0.00% | Reduce -44.9% | 122,100 | $3.3M |
| Schroder Investment Management Group | 0.00% | No change | 130,592 | $3.1M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 112,190 | $3.0M |
| Nuveen, LLC | 0.00% | Reduce -8.9% | 112,007 | $3.0M |
| Squarepoint Ops LLC | 0.01% | Reduce -57.3% | 105,491 | $2.9M |
| Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A. | 0.24% | Reduce -84.1% | 104,961 | $2.8M |
| Capital Fund Management S.A. | 0.02% | New | 102,202 | $2.8M |
| UBS Group AG | 0.00% | Reduce -51.3% | 98,029 | $2.7M |
| HRT Financial LP | 0.01% | Add +157.6% | 95,920 | $2.6M |
| Verition Fund Management LLC | 0.03% | Add +13.5% | 95,122 | $2.6M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -26.2% | 94,358 | $2.6M |
| J. Goldman & Co LP | 0.12% | Add +99.0% | 94,101 | $2.5M |
| Brevan Howard Capital Management LP | 0.03% | Reduce -34.7% | 90,929 | $2.5M |
| Swiss National Bank | 0.00% | No change | 90,100 | $2.4M |
| CenterBook Partners LP | 0.13% | Add +243.6% | 89,330 | $2.4M |
| Ishara Investments LP | 2.24% | New | 82,000 | $2.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +4.8% | 79,537 | $2.2M |
| Susquehanna Portfolio Strategies, LLC | 0.03% | No change | 78,092 | $2.1M |
| Hennion & Walsh Asset Management, Inc. | 0.06% | Add +1.2% | 70,189 | $1.9M |
| Seven Fleet Capital Management LP | 0.59% | Add +65.5% | 69,571 | $1.9M |
| XTX Topco Ltd | 0.03% | Reduce -7.2% | 68,407 | $1.9M |
| Alps Advisors Inc. | 0.01% | Reduce -0.9% | 64,419 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Add +28.4% | 64,138 | $1.7M |
| California State Teachers Retirement System | 0.00% | Add +41.3% | 61,266 | $1.7M |
| Prudential Financial Inc. | 0.00% | Reduce -33.1% | 59,555 | $1.6M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.00% | Reduce -47.0% | 59,242 | $1.6M |
| Greenland Capital Management LP | 0.36% | Reduce -16.7% | 57,500 | $1.6M |
| Rhumbline Advisers | 0.00% | Add +5.8% | 57,444 | $1.6M |
| Trexquant Investment LP | 0.01% | Reduce -49.3% | 57,200 | $1.5M |
| Canada Pension Plan Investment Board | 0.00% | Add +73.7% | 51,400 | $1.4M |
| Los Angeles Capital Management LLC | 0.01% | Add +16930.9% | 46,835 | $1.3M |
| HighVista Strategies LLC | 0.35% | Reduce -62.4% | 46,778 | $1.3M |
| JPMorgan Chase & Co. | 0.00% | Add +11.2% | 51,922 | $1.2M |
| Invesco Ltd. | 0.00% | Add +45.2% | 42,311 | $1.1M |
| Profund Advisors LLC | 0.04% | Reduce -10.7% | 41,984 | $1.1M |
| Deutsche Bank AG | 0.00% | Add +7.7% | 40,116 | $1.1M |
| Erste Asset Management GmbH | 0.01% | No change | 45,000 | $1.1M |
| DAFNA Capital Management LLC | 0.24% | No change | 38,490 | $1.0M |
| Legal & General Group Plc | 0.00% | Reduce -12.4% | 38,473 | $1.0M |
| Barclays PLC | 0.00% | Reduce -84.8% | 33,877 | $918K |
| Victory Capital Management Inc. | 0.00% | Add +0.8% | 33,141 | $898K |
| Sectoral Asset Management Inc. | 0.74% | Reduce -0.0% | 31,618 | $895K |
| Vanguard Global Advisers, LLC | 0.00% | — | 30,474 | $826K |
| Bellevue Group AG | 0.02% | Add +48.2% | 29,374 | $796K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 29,253 | $792K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +0.0% | 29,185 | $767K |
| MetLife Investment Management, LLC | 0.00% | Add +3.2% | 26,826 | $727K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +63.2% | 26,411 | $715K |
| Diadema Partners LP | 0.29% | Add +5.4% | 26,347 | $714K |
| Wells Fargo & Company | 0.00% | Reduce -54.0% | 26,081 | $707K |
| Raymond James Financial Inc. | 0.00% | Reduce -1.2% | 24,677 | $669K |
| Creative Planning | 0.00% | Add +15.2% | 24,301 | $658K |
| Allianz Asset Management GmbH | 0.00% | Reduce -27.5% | 21,900 | $593K |
| Quantinno Capital Management LP | 0.00% | Add +12.6% | 20,541 | $556K |
| Nomura Holdings Inc. | 0.00% | New | 20,000 | $542K |
| Janus Henderson Group PLC | 0.00% | Reduce -98.4% | 19,848 | $537K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +64.1% | 19,689 | $533K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +13.2% | 19,641 | $532K |
| Simplex Trading, LLC | 0.02% | Add +307.4% | 19,562 | $530K |
| Magnetar Financial LLC | 0.01% | New | 18,549 | $502K |
| Eleva Capital SAS | 0.13% | — | 17,081 | $463K |
| BNP Paribas Financial Markets | 0.00% | Reduce -90.3% | 16,716 | $453K |
| Susquehanna International Group, LLP | 0.00% | Reduce -89.0% | 15,770 | $427K |
| State of New Jersey Common Pension Fund D | 0.00% | Add +0.1% | 15,604 | $423K |
| Persistent Asset Partners Ltd | 0.16% | Add +107.7% | 15,401 | $417K |
| New York State Common Retirement Fund | 0.00% | Add +22.3% | 15,364 | $416K |
| Citigroup Inc. | 0.00% | Reduce -17.6% | 15,085 | $409K |
| Handelsbanken Fonder AB | 0.00% | No change | 14,100 | $382K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +8.9% | 14,044 | $380K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 12,683 | $344K |
| Arizona State Retirement System | 0.00% | Reduce -3.5% | 12,542 | $340K |
| MAI Capital Management | 0.00% | Add +50887.5% | 12,237 | $332K |
| E Fund Management Co., Ltd. | 0.01% | — | 11,862 | $321K |
| Sei Investments Co. | 0.00% | Add +33.2% | 11,692 | $317K |
| Intech Investment Management LLC | 0.00% | Reduce -32.7% | 11,259 | $305K |
| Velan Capital Investment Management LP | 0.19% | Reduce -92.7% | 11,000 | $298K |
| Fox Run Management, L.L.C. | 0.05% | Reduce -12.8% | 12,670 | $298K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 10,765 | $292K |
| CreativeOne Wealth, LLC | 0.01% | No change | 10,750 | $291K |
| Lion Point Capital, LP | 1.70% | No change | 10,500 | $284K |
| ProShare Advisors LLC | 0.00% | Reduce -13.1% | 10,459 | $283K |
| KLP Kapitalforvaltning As | 0.00% | Add +8.3% | 10,400 | $282K |
| Entropy Technologies, LP | 0.01% | Reduce -37.1% | 10,180 | $276K |
| Man Group plc | 0.00% | New | 10,139 | $275K |
| Quarry LP | 0.06% | New | 10,000 | $271K |
| VARCOV Co. | 0.10% | New | 9,759 | $264K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | Add +4.3% | 9,750 | $264K |
| Capstone Investment Advisors, LLC | 0.00% | New | 9,675 | $262K |
| Kingswood Wealth Advisors, LLC | 0.01% | Add +35.7% | 9,600 | $260K |
| Marshall Wace, LLP | 0.00% | Reduce -96.4% | 8,987 | $243K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +1423.7% | 7,923 | $215K |
| State Board of Administration of Florida Retirement System | 0.00% | Add +1.5% | 7,672 | $208K |
| Virtus Investment Advisers, LLC | 0.06% | Add +2.5% | 7,389 | $200K |
| Cwm, LLC | 0.00% | Add +18.7% | 6,051 | $164K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +7.3% | 4,128 | $112K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,798 | $103K |
| Nisa Investment Advisors, LLC | 0.00% | Add +21.0% | 2,359 | $64K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 2,234 | $61K |
| GF Fund Management Co. LTD. | 0.00% | Add +14.3% | 1,777 | $48K |
| Smartleaf Asset Management LLC | 0.00% | Add +63.4% | 1,639 | $39K |
| KBC Group NV | 0.00% | New | 1,233 | $33K |
| Osaic Holdings, Inc. | 0.00% | Add +0.4% | 1,160 | $31K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 837 | $23K |
| Fifth Third Bancorp | 0.00% | New | 784 | $21K |
| Rockefeller Capital Management L.P. | 0.00% | Add +314.2% | 555 | $15K |
| Covestor Ltd | 0.01% | Add +19.9% | 567 | $15K |
| Versant Capital Management, Inc | 0.00% | No change | 513 | $14K |
| FNY Investment Advisers, LLC | 0.01% | New | 500 | $13K |
| GAMMA Investing LLC | 0.00% | Add +5.1% | 474 | $13K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | No change | 355 | $10K |
| Allworth Financial LP | 0.00% | Add +61.6% | 354 | $10K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 319 | $9K |
| Sterling Capital Management LLC | 0.00% | No change | 306 | $8K |
| US Bancorp \de | 0.00% | Add +272.8% | 302 | $8K |
| J.Safra Asset Management Corp | 0.00% | Add +208.6% | 250 | $7K |
| FIL Ltd | 0.00% | New | 229 | $6K |
| Keating Financial Advisory Services, Inc. | 0.00% | New | 226 | $6K |
| SMA Capital LLC | 0.00% | New | 208 | $6K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +27.3% | 196 | $5K |
| Royal Bank of Canada | 0.00% | Reduce -90.1% | 152 | $4K |
| SBI Securities Co., Ltd. | 0.00% | Add +0.9% | 117 | $3K |
| Rothschild Investment LLC | 0.00% | Add +67.3% | 92 | $2K |
| Optiver Holding B.V. | 0.00% | Add +90.5% | 80 | $2K |
| True Wealth Design, LLC | 0.00% | No change | 76 | $2K |
| Kilter Group LLC | 0.00% | New | 69 | $2K |
| Arax Advisory Partners | 0.00% | Reduce -36.7% | 69 | $2K |
| Advisory Services Network, LLC | 0.00% | New | 41 | $1K |
| Farther Finance Advisors, LLC | 0.00% | Add +5.7% | 37 | $977 |
| Parkside Financial Bank & Trust | 0.00% | No change | 35 | $948 |
| Private Wealth Management Group, LLC | 0.00% | No change | 28 | $759 |
| Parallel Advisors, LLC | 0.00% | No change | 22 | $596 |
| SJS Investment Consulting Inc. | 0.00% | New | 12 | $326 |
| Clearstead Advisors, LLC | 0.00% | No change | 11 | $298 |
| Larson Financial Group LLC | 0.00% | Reduce -96.1% | 6 | $163 |
| Basecamp Wealth Advisors LLC | 0.00% | New | 6 | $163 |
| Quadrant Capital Group LLC | 0.00% | Reduce -37.5% | 5 | $136 |
| Stone House Investment Management, LLC | 0.00% | New | 4 | $108 |
| JPL Wealth Management, LLC | 0.00% | New | 3 | $82 |
| Hughes Financial Services, LLC | 0.00% | New | 2 | $54 |
| IFP Advisors, Inc | 0.00% | Reduce -87.5% | 1 | $27 |
| Essential Partners LLC | 0.00% | No change | 1 | $27 |
| Avion Wealth | 0.00% | No change | 21 | $0 |
"% of holder's portfolio" is MLYS's weight in each manager's 13F, not the share of Mineralys Therapeutics Inc. the manager owns.