Mereo Biopharma Group PL-ADRMREO

13F holders, Q4 2025 (December 31)
70holders −14
21new positions
35sold out
2famous investors
$0.42avg. 13F price*

At the end of Q4 2025, 70 institutions reported holding Mereo Biopharma Group PL-ADR (MREO) in their 13F filings, down 14 from Q3 2025. 21 opened new positions and 35 sold out. The largest holders were Rubric Capital Management LP ($6.4M), 683 Capital Management, LLC ($6.3M) and EcoR1 Capital, LLC ($3.3M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Mereo Biopharma Group PL-ADR
CUSIP
589492107
Latest filing quarter
Q2 2026

History

Number of 13F holders

020406080100 Q1 2024: 80Q1 2024Q2 2024: 79Q2 2024Q3 2024: 77Q3 2024Q4 2024: 91Q4 2024Q1 2025: 90Q1 2025Q2 2025: 86Q2 2025Q3 2025: 84Q3 2025Q4 2025: 70Q4 2025Q1 2026: 63Q1 2026Q2 2026: 60Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions21$4.9M
Exits35$124.5M

All 13F filers, Q3 2025 → Q4 2025: 29,725,905 shares bought and 67,935,095 shares sold, net −38,209,190 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 70 holders

Rubric Capital Management LP 0.08% No change 15,307,347 $6.4M
683 Capital Management, LLC 0.55% Add +208.2% 15,025,000 $6.3M
EcoR1 Capital, LLC 0.15% New 7,856,466 $3.3M
Schonfeld Strategic Advisors LLC 0.01% Add +251.5% 6,090,381 $2.5M
Tejara Capital Ltd 0.37% Add +13.3% 2,159,681 $900K
Logos Global Management LP 0.05% Add +270.0% 1,850,000 $771K
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Reduce -7.5% 1,763,666 $735K
Monaco Asset Management SAM 0.20% Add +67.6% 1,585,214 $661K
UBS Group AG 0.00% Add +60.6% 1,558,931 $650K
Balyasny Asset Management L.P. 0.00% New 1,280,275 $533K
Morgan Stanley 0.00% Reduce -61.9% 1,273,785 $531K
Two Sigma Investments, LP 0.00% Reduce -51.7% 525,125 $219K
Group One Trading LLC 0.01% Add +223.3% 441,636 $184K
Simplex Trading, LLC 0.00% Add +113.7% 419,477 $175K
EntryPoint Capital, LLC 0.07% New 400,700 $167K
Luminus Management LLC 0.15% New 395,000 $165K
Rangeley Capital, LLC 0.13% New 364,000 $152K
Jane Street Group, LLC 0.00% Reduce -21.3% 356,004 $148K
BlackRock, Inc. 0.00% Reduce -29.6% 312,613 $130K
Knott David M Jr 0.06% No change 300,337 $125K
Quadrature Capital Ltd 0.00% New 266,731 $111K
Sphera Funds Management LTD. 0.02% New 255,400 $106K
Two Sigma Advisers, LP 0.00% Add +4.0% 251,900 $105K
Newtyn Management, LLC 0.01% New 224,622 $94K
Citigroup Inc. 0.00% New 195,814 $82K
Renaissance Technologies 0.00% Reduce -67.1% 194,371 $81K
ADAR1 Capital Management, LLC 0.00% New 150,000 $63K
State Street Corp. 0.00% Reduce -1.6% 130,643 $54K
Virtus Investment Advisers, LLC 0.01% Add +199.5% 122,595 $51K
Graham Capital Management, L.P. 0.00% New 116,286 $48K
Geode Capital Management, LLC 0.00% No change 92,534 $39K
Millennium Management 0.00% Reduce -75.2% 83,646 $35K
Baader Bank Aktiengesellschaft 0.00% New 128,742 $33K
Acadian Asset Management LLC 0.00% Reduce -76.0% 61,435 $24K
Caption Management, LLC 0.00% Reduce -73.7% 50,000 $21K
Engineers Gate Manager LP 0.00% New 49,798 $21K
Clear Harbor Asset Management, LLC 0.00% Reduce -54.5% 35,000 $15K
Forefront Analytics, LLC 0.01% Reduce -4.3% 31,768 $13K
Goldman Sachs Group Inc. 0.00% Reduce -98.8% 28,026 $12K
Bank of America Corp. 0.00% Reduce -94.2% 25,492 $11K
Centiva Capital, LP 0.00% No change 25,000 $10K
Significant Wealth Partners LLC 0.01% Reduce -54.6% 21,689 $9K
Aquatic Capital Management LLC 0.00% Reduce -60.5% 21,216 $9K
SmartHarvest Portfolios, LLC 0.00% — 20,290 $8K
Rhumbline Advisers 0.00% Add +109.9% 19,146 $8K
Three Magnolias Financial Advisors, LLC 0.00% Reduce -48.6% 19,000 $8K
OneDigital Investment Advisors LLC 0.00% No change 18,300 $8K
NFSG Corp 0.00% Add +30.8% 17,000 $7K
PFG Investments, LLC 0.00% Reduce -2.9% 16,650 $7K
Barclays PLC 0.00% New 14,500 $6K
QRG Capital Management, Inc. 0.00% New 13,503 $6K
AE Wealth Management LLC 0.00% New 12,563 $5K
MML Investors Services, LLC 0.00% New 12,200 $5K
Astoria Portfolio Advisors LLC. 0.00% New 10,000 $4K
GAMMA Investing LLC 0.00% Add +4.1% 9,561 $4K
Toronto Dominion Bank 0.00% New 5,500 $2K
Arax Advisory Partners 0.00% No change 4,000 $2K
Caitong International Asset Management Co., Ltd 0.00% Reduce -73.7% 2,231 $930
Rockefeller Capital Management L.P. 0.00% No change 2,000 $833
Wells Fargo & Company 0.00% Add +655.2% 1,737 $724
Allworth Financial LP 0.00% Add +2.4% 1,611 $672
Osaic Holdings, Inc. 0.00% Reduce -91.2% 500 $208
EverSource Wealth Advisors, LLC 0.00% No change 417 $174
MAI Capital Management 0.00% No change 309 $129
New England Capital Financial Advisors LLC 0.00% No change 300 $126
SageView Advisory Group, LLC 0.00% New 161 $68
Farther Finance Advisors, LLC 0.00% New 17 $7
US Bancorp \de 0.00% No change 13 $5
BNP Paribas Financial Markets 0.00% No change 3 $1
Sit Investment Associates Inc. 0.00% No change 970 $0

"% of holder's portfolio" is MREO's weight in each manager's 13F, not the share of Mereo Biopharma Group PL-ADR the manager owns.