Orchestra Biomed HoldingsOBIO
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 59 institutions reported holding Orchestra Biomed Holdings Inc. (OBIO) in their 13F filings, up 3 from Q1 2025. 21 opened new positions and 19 sold out. The largest holders were RTW Investments, LP ($22.3M), Perceptive Advisors LLC ($12.3M) and Vanguard Group Inc. ($3.1M). 3 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Orchestra Biomed Holdings Inc.
- CUSIP
- 68572M106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 21 | $3.0M |
| Exits | 19 | $963K |
All 13F filers, Q1 2025 → Q2 2025: 1,817,966 shares bought and 2,675,121 shares sold, net −857,155 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 59 holders
| RTW Investments, LP | 0.32% | Add +1.2% | 8,306,062 | $22.3M |
| Perceptive Advisors LLC | 0.46% | No change | 4,592,556 | $12.3M |
| Vanguard Group Inc. | 0.00% | Reduce -11.5% | 1,157,317 | $3.1M |
| BlackRock, Inc. | 0.00% | Reduce -65.0% | 681,349 | $1.8M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -4.7% | 438,369 | $1.2M |
| Millennium Management | 0.00% | New | 409,674 | $1.1M |
| Geode Capital Management, LLC | 0.00% | Reduce -49.3% | 302,082 | $810K |
| Renaissance Technologies | 0.00% | New | 169,400 | $454K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -36.1% | 138,591 | $371K |
| State Street Corp. | 0.00% | Reduce -72.5% | 130,133 | $349K |
| Susquehanna International Group, LLP | 0.00% | Add +259.4% | 118,558 | $318K |
| Northern Trust Corp. | 0.00% | Reduce -57.9% | 100,435 | $269K |
| Knott David M Jr | 0.12% | New | 100,000 | $268K |
| Goldman Sachs Group Inc. | 0.00% | Add +98.7% | 96,841 | $260K |
| TD Asset Management Inc | 0.00% | No change | 92,678 | $248K |
| IFP Advisors, Inc | 0.01% | Reduce -47.3% | 85,358 | $229K |
| HighTower Advisors, LLC | 0.00% | Add +9.0% | 66,500 | $178K |
| Knoll Capital Management, LLC | 0.12% | New | 455,128 | $170K |
| Lasry Marc | 0.91% | No change | 60,869 | $163K |
| Holos Integrated Wealth LLC | 0.08% | No change | 51,595 | $140K |
| Marshall Wace, LLP | 0.00% | New | 49,465 | $133K |
| Citadel Advisors | 0.00% | Add +141.4% | 49,441 | $133K |
| Y-Intercept (Hong Kong) Ltd | 0.00% | New | 45,447 | $122K |
| NewEdge Advisors, LLC | 0.00% | New | 44,083 | $118K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -22.6% | 32,518 | $87K |
| Squarepoint Ops LLC | 0.00% | New | 28,221 | $76K |
| HRT Financial LP | 0.00% | New | 28,217 | $75K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +1137.7% | 27,922 | $75K |
| UBS Group AG | 0.00% | Add +51.4% | 26,139 | $70K |
| Bridgeway Capital Management, LLC | 0.00% | New | 25,000 | $67K |
| Jain Global LLC | 0.00% | New | 24,462 | $66K |
| Dimensional Fund Advisors LP | 0.00% | New | 22,207 | $60K |
| Bank of America Corp. | 0.00% | Add +35.7% | 21,577 | $58K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.01% | New | 18,710 | $50K |
| Jane Street Group, LLC | 0.00% | New | 18,513 | $50K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 17,716 | $47K |
| XTX Topco Ltd | 0.00% | New | 16,817 | $45K |
| Creative Planning | 0.00% | New | 15,000 | $40K |
| ABLE Financial Group, LLC | 0.01% | No change | 13,402 | $36K |
| Morgan Stanley | 0.00% | Reduce -58.4% | 13,382 | $36K |
| Catalyst Funds Management Pty Ltd | 0.01% | New | 11,400 | $31K |
| Royal Bank of Canada | 0.00% | Add +1175.1% | 7,829 | $21K |
| Citigroup Inc. | 0.00% | Reduce -55.5% | 7,661 | $21K |
| Wells Fargo & Company | 0.00% | Reduce -66.7% | 4,474 | $12K |
| BNP Paribas Financial Markets | 0.00% | Add +31.1% | 2,405 | $6K |
| Harbour Investments, Inc. | 0.00% | No change | 1,988 | $5K |
| Larson Financial Group LLC | 0.00% | Add +8.3% | 1,983 | $5K |
| FMR LLC | 0.00% | Add +50.2% | 1,646 | $4K |
| Barclays PLC | 0.00% | Reduce -96.6% | 874 | $2K |
| SBI Securities Co., Ltd. | 0.00% | Add +68000.0% | 681 | $2K |
| JPMorgan Chase & Co. | 0.00% | Reduce -96.1% | 470 | $1K |
| Cwm, LLC | 0.00% | Add +693.8% | 381 | $1K |
| Point72 (DIFC) Ltd | 0.00% | New | 354 | $949 |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -70.1% | 241 | $646 |
| Fortitude Family Office, LLC | 0.00% | New | 203 | $544 |
| Russell Investments Group, Ltd. | 0.00% | New | 193 | $517 |
| Sierra Ocean, LLC | 0.00% | No change | 119 | $319 |
| Essential Partners LLC | 0.00% | — | 4 | $11 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -80.0% | 1 | $3 |
"% of holder's portfolio" is OBIO's weight in each manager's 13F, not the share of Orchestra Biomed Holdings Inc. the manager owns.