Puma BiotechnologyPBYI
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 157 institutions reported holding Puma Biotechnology Inc. (PBYI) in their 13F filings, up 6 from Q4 2025. 23 opened new positions and 17 sold out. The largest holders were Acorn Capital Advisors, LLC ($26.4M), BlackRock, Inc. ($23.0M) and Acadian Asset Management LLC ($13.0M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Puma Biotechnology Inc.
- CUSIP
- 74587V107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $1.6M |
| Exits | 17 | $3.7M |
All 13F filers, Q4 2025 → Q1 2026: 4,518,189 shares bought and 1,952,096 shares sold, net +2,566,093 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 157 holders
| Acorn Capital Advisors, LLC | 7.50% | No change | 4,131,299 | $26.4M |
| BlackRock, Inc. | 0.00% | Reduce -1.2% | 3,598,952 | $23.0M |
| Acadian Asset Management LLC | 0.02% | Add +0.8% | 2,041,759 | $13.0M |
| Renaissance Technologies | 0.02% | Reduce -8.5% | 1,942,413 | $12.4M |
| American Century Companies Inc. | 0.01% | Add +16.1% | 1,916,346 | $12.2M |
| Vanguard Capital Management LLC | 0.00% | — | 1,817,681 | $11.6M |
| Vanguard Portfolio Management LLC | 0.00% | — | 1,734,649 | $11.1M |
| Millennium Management | 0.01% | Add +8793.2% | 1,477,519 | $9.4M |
| Dimensional Fund Advisors LP | 0.00% | Add +7.2% | 1,436,106 | $9.2M |
| LSV Asset Management | 0.02% | Add +192.2% | 1,182,868 | $7.6M |
| O'shaughnessy Asset Management, LLC | 0.04% | Add +1.6% | 1,138,169 | $7.3M |
| Geode Capital Management, LLC | 0.00% | Add +2.3% | 1,017,342 | $6.5M |
| State Street Corp. | 0.00% | Add +4.6% | 917,590 | $5.9M |
| Kennedy Capital Management LLC | 0.12% | Add +2.5% | 889,601 | $5.7M |
| AQR Capital Management | 0.00% | Add +20.0% | 800,194 | $5.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -10.6% | 782,798 | $5.0M |
| Bridgeway Capital Management, LLC | 0.10% | Add +0.2% | 775,341 | $5.0M |
| Ritholtz Wealth Management | 0.09% | Add +11.6% | 774,308 | $4.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -15.7% | 669,719 | $4.3M |
| Northern Trust Corp. | 0.00% | Add +4.2% | 641,753 | $4.1M |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -1.8% | 538,155 | $3.4M |
| UBS Group AG | 0.00% | Add +319.6% | 534,227 | $3.4M |
| Sei Investments Co. | 0.00% | Add +18.2% | 508,182 | $3.2M |
| Morgan Stanley | 0.00% | Add +10.1% | 359,742 | $2.3M |
| D. E. Shaw & Co. | 0.00% | Reduce -7.2% | 351,235 | $2.2M |
| Globeflex Capital L P | 0.34% | Reduce -22.8% | 349,651 | $2.2M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.1% | 347,881 | $2.2M |
| State Board of Administration of Florida Retirement System | 0.00% | Add +898.3% | 272,890 | $1.7M |
| Prudential Financial Inc. | 0.00% | Reduce -11.7% | 253,039 | $1.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 251,683 | $1.6M |
| Russell Investments Group, Ltd. | 0.00% | No change | 251,653 | $1.6M |
| Federated Hermes, Inc. | 0.00% | Reduce -0.1% | 237,715 | $1.5M |
| Franklin Resources Inc. | 0.00% | Add +17.9% | 215,391 | $1.4M |
| JPMorgan Chase & Co. | 0.00% | Add +945.7% | 220,724 | $1.4M |
| State of Wisconsin Investment Board | 0.00% | Add +56.0% | 208,618 | $1.3M |
| Empowered Funds, LLC | 0.01% | Add +9.6% | 204,041 | $1.3M |
| Panagora Asset Management Inc. | 0.00% | No change | 194,887 | $1.2M |
| FMR LLC | 0.00% | Add +17.1% | 191,833 | $1.2M |
| Prospera Financial Services Inc | 0.02% | Reduce -6.7% | 173,051 | $1.1M |
| Haven Private, LLC | 0.43% | Add +68.6% | 155,260 | $992K |
| Round Rock Advisors LLC | 0.13% | Add +22.7% | 128,912 | $824K |
| First Trust Advisors LP | 0.00% | Add +0.6% | 123,513 | $789K |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -7.5% | 115,915 | $741K |
| Evergreen Capital Management LLC | 0.01% | No change | 96,000 | $613K |
| Invesco Ltd. | 0.00% | Reduce -12.2% | 95,044 | $607K |
| STRS Ohio | 0.00% | Reduce -8.0% | 91,500 | $585K |
| OpenArc Corporate Advisory, LLC | 0.01% | Add +0.1% | 89,491 | $572K |
| Nuveen, LLC | 0.00% | No change | 79,101 | $505K |
| State of Wyoming | 0.06% | Add +42.6% | 75,808 | $484K |
| WINTON GROUP Ltd | 0.01% | Reduce -31.7% | 66,333 | $424K |
| Nomura Asset Management International Inc. | 0.00% | No change | 61,255 | $391K |
| EntryPoint Capital, LLC | 0.10% | Add +51.1% | 53,464 | $342K |
| Rhumbline Advisers | 0.00% | Reduce -1.6% | 53,036 | $339K |
| D'Orazio & Associates, Inc. | 0.04% | Add +0.2% | 49,915 | $319K |
| Man Group plc | 0.00% | Add +0.1% | 47,375 | $303K |
| Bank of America Corp. | 0.00% | Reduce -22.9% | 40,364 | $258K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | No change | 39,308 | $251K |
| Baron Wealth Management LLC | 0.07% | Add +8.2% | 38,278 | $245K |
| Vise Technologies, Inc. | 0.00% | No change | 40,298 | $240K |
| LPL Financial LLC | 0.00% | Reduce -9.5% | 36,618 | $234K |
| Deutsche Bank AG | 0.00% | New | 33,145 | $212K |
| T. Rowe Price Associates Inc. | 0.00% | Add +20.7% | 31,306 | $201K |
| Citadel Advisors | 0.00% | Reduce -81.6% | 29,959 | $191K |
| Kathmere Capital Management, LLC | 0.01% | Add +9.8% | 29,779 | $190K |
| Virtus Advisers, LLC | 0.09% | Reduce -37.8% | 29,347 | $188K |
| Vanguard Global Advisers, LLC | 0.00% | — | 29,173 | $186K |
| Engineers Gate Manager LP | 0.00% | Add +52.2% | 28,600 | $183K |
| Envestnet Asset Management Inc. | 0.00% | New | 26,558 | $170K |
| Caprock Group, LLC | 0.00% | Add +58.0% | 25,989 | $166K |
| Metis Global Partners, LLC | 0.00% | Reduce -40.7% | 25,264 | $161K |
| C2C Wealth Management, LLC | 0.13% | Add +2.6% | 23,620 | $151K |
| Creative Planning | 0.00% | New | 23,113 | $148K |
| Canada Pension Plan Investment Board | 0.00% | Reduce -69.7% | 22,800 | $146K |
| One Wealth Advisors, LLC | 0.02% | Add +8.7% | 21,079 | $135K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.4% | 20,635 | $132K |
| Prelude Capital Management, LLC | 0.01% | Reduce -42.6% | 18,448 | $118K |
| Bailard, Inc. | 0.00% | New | 18,100 | $116K |
| Lazard Asset Management LLC | 0.00% | Reduce -69.8% | 17,970 | $115K |
| Allspring Global Investments Holdings, LLC | 0.00% | New | 17,066 | $109K |
| Quadrature Capital Ltd | 0.00% | New | 16,745 | $107K |
| Wells Fargo & Company | 0.00% | Reduce -66.3% | 16,273 | $104K |
| Susquehanna International Group, LLP | 0.00% | New | 16,089 | $103K |
| MetLife Investment Management, LLC | 0.00% | Reduce -35.1% | 15,842 | $101K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 15,719 | $100K |
| Cwm, LLC | 0.00% | Add +19.1% | 15,263 | $98K |
| XTX Topco Ltd | 0.00% | New | 15,116 | $97K |
| Ieq Capital, LLC | 0.00% | Add +29.6% | 14,901 | $95K |
| Mariner, LLC | 0.00% | New | 14,649 | $94K |
| Barclays PLC | 0.00% | Reduce -82.8% | 13,988 | $89K |
| Ashton Thomas Private Wealth, LLC | 0.00% | New | 13,500 | $86K |
| Cerity Partners LLC | 0.00% | Add +7.8% | 13,013 | $83K |
| Two Sigma Investments, LP | 0.00% | Reduce -92.0% | 13,000 | $83K |
| HRT Financial LP | 0.00% | New | 13,073 | $83K |
| Tocqueville Asset Management L.P. | 0.00% | New | 12,960 | $83K |
| Alliancebernstein L.P. | 0.00% | No change | 13,800 | $82K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +14.7% | 11,635 | $80K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | Reduce -78.8% | 12,563 | $80K |
| Perkins Capital Management Inc. | 0.07% | No change | 12,500 | $80K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -12.4% | 11,765 | $75K |
| Osaic Holdings, Inc. | 0.00% | Reduce -4.1% | 11,669 | $75K |
| Abel Hall, LLC | 0.02% | Add +6.3% | 11,474 | $73K |
| Williams & Novak, LLC | 0.05% | Add +0.8% | 10,639 | $72K |
| Abacus Wealth Partners, LLC | 0.01% | New | 11,199 | $72K |
| Ethic Inc. | 0.00% | Reduce -0.2% | 10,530 | $67K |
| DGS Capital Management, LLC | 0.01% | New | 10,418 | $67K |
| Stokes Family Office, LLC | 0.01% | Reduce -64.1% | 10,092 | $64K |
| BNP Paribas Financial Markets | 0.00% | Reduce -0.9% | 9,667 | $62K |
| China Universal Asset Management Co., Ltd. | 0.00% | Add +9.9% | 9,028 | $58K |
| Philadelphia Investment Partners, LLC | 0.04% | — | 9,000 | $58K |
| State of Alaska, Department of Revenue | 0.00% | No change | 8,445 | $53K |
| MAI Capital Management | 0.00% | Add +20327.0% | 7,558 | $48K |
| IFP Advisors, Inc | 0.00% | Add +3286.3% | 6,908 | $44K |
| Royal Bank of Canada | 0.00% | Add +244.5% | 4,320 | $28K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 4,055 | $26K |
| New York State Common Retirement Fund | 0.00% | No change | 3,600 | $23K |
| Legal & General Group Plc | 0.00% | No change | 3,564 | $23K |
| Private Wealth Asset Management, LLC | 0.00% | No change | 3,500 | $22K |
| Citigroup Inc. | 0.00% | Add +43.8% | 3,422 | $22K |
| Ball & Co Wealth Management Inc. | 0.02% | No change | 3,066 | $19K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +8.4% | 2,654 | $17K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +14.7% | 2,568 | $16K |
| California State Teachers Retirement System | 0.00% | Reduce -12.1% | 2,330 | $15K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 1,710 | $11K |
| Rialto Wealth Management, LLC | 0.00% | No change | 1,450 | $9K |
| Sterling Capital Management LLC | 0.00% | Reduce -42.6% | 1,425 | $9K |
| Group One Trading LLC | 0.00% | Reduce -85.4% | 1,344 | $9K |
| GHP Investment Advisors, Inc. | 0.00% | No change | 1,170 | $7K |
| WealthCollab, LLC | 0.00% | No change | 1,156 | $7K |
| Intentional Wealth Strategies, LLC | 0.01% | — | 1,128 | $7K |
| GF Fund Management Co. LTD. | 0.00% | Add +13.4% | 1,122 | $7K |
| Rockefeller Capital Management L.P. | 0.00% | Add +398.7% | 793 | $5K |
| Farther Finance Advisors, LLC | 0.00% | Add +7.0% | 566 | $4K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 513 | $3K |
| Harbour Investments, Inc. | 0.00% | New | 500 | $3K |
| Essential Partners LLC | 0.00% | Add +0.5% | 443 | $3K |
| GAMMA Investing LLC | 0.00% | Add +203.6% | 422 | $3K |
| Optiver Holding B.V. | 0.00% | Reduce -45.8% | 416 | $3K |
| Rothschild Investment LLC | 0.00% | Add +38.6% | 406 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +51.9% | 360 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 342 | $2K |
| Allworth Financial LP | 0.00% | Add +582.0% | 341 | $2K |
| Root Financial Partners, LLC | 0.00% | New | 269 | $2K |
| Arax Advisory Partners | 0.00% | Add +21730.0% | 2,183 | $1K |
| US Bancorp \de | 0.00% | No change | 200 | $1K |
| Frazier Financial Advisors, LLC | 0.00% | New | 183 | $1K |
| Mosley Wealth Management | 0.00% | New | 148 | $786 |
| True Wealth Design, LLC | 0.00% | No change | 123 | $786 |
| Basecamp Wealth Advisors LLC | 0.00% | New | 86 | $550 |
| Jones Financial Companies LLLP | 0.00% | No change | 68 | $413 |
| SBI Securities Co., Ltd. | 0.00% | No change | 56 | $358 |
| SJS Investment Consulting Inc. | 0.00% | Add +19.4% | 43 | $275 |
| Sunbelt Securities, Inc. | 0.00% | No change | 30 | $192 |
| Fifth Third Bancorp | 0.00% | New | 8 | $51 |
| Inspire Investing, LLC | 0.00% | No change | 5 | $31 |
| Elevation Wealth Partners, LLC | 0.00% | No change | 3 | $20 |
| TFC Financial Management, Inc. | 0.00% | New | 1 | $7 |
| Wealth Preservation Advisors, LLC | 0.00% | New | 1 | $6 |
"% of holder's portfolio" is PBYI's weight in each manager's 13F, not the share of Puma Biotechnology Inc. the manager owns.