Praxis Precision Medicines IPRAX
13F holders, Q1 2025 (March 31)At the end of Q1 2025, 150 institutions reported holding Praxis Precision Medicines I (PRAX) in their 13F filings, down 12 from Q4 2024. 33 opened new positions and 44 sold out. The largest holders were Cormorant Asset Management, LP ($66.1M), Adage Capital Partners Gp, L.L.C. ($66.0M) and Janus Henderson Group PLC ($58.3M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Praxis Precision Medicines I
- CUSIP
- 74006W207
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $65.0M |
| Exits | 44 | $133.4M |
All 13F filers, Q4 2024 → Q1 2025: 6,114,135 shares bought and 4,090,757 shares sold, net +2,023,378 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 150 holders
| Cormorant Asset Management, LP | 5.00% | Add +3.1% | 1,745,000 | $66.1M |
| Adage Capital Partners Gp, L.L.C. | 0.12% | Add +188.1% | 1,742,758 | $66.0M |
| Janus Henderson Group PLC | 0.03% | Add +62.1% | 1,506,436 | $58.3M |
| BlackRock, Inc. | 0.00% | Reduce -3.1% | 1,416,935 | $53.7M |
| Morgan Stanley | 0.00% | Add +4.3% | 1,213,669 | $46.0M |
| Soleus Capital Management, L.P. | 3.38% | Add +368.0% | 1,139,740 | $43.2M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -9.3% | 1,095,725 | $41.5M |
| Vanguard Group Inc. | 0.00% | Add +2.2% | 1,087,020 | $41.2M |
| Venrock Adviser, LLC | 3.19% | No change | 989,985 | $37.5M |
| Perceptive Advisors LLC | 1.32% | Reduce -26.2% | 980,894 | $37.1M |
| Capital Research Global Investors | 0.01% | Reduce -14.1% | 853,746 | $32.3M |
| State Street Corp. | 0.00% | Reduce -4.1% | 737,039 | $27.9M |
| Deerfield Management Company, L.P. | 0.53% | New | 619,931 | $23.5M |
| Assenagon Asset Management S.A. | 0.03% | Reduce -9.2% | 507,400 | $19.2M |
| Driehaus Capital Management LLC | 0.18% | Add +192.0% | 481,598 | $18.2M |
| Bank of America Corp. | 0.00% | Add +8270.4% | 460,707 | $17.4M |
| Geode Capital Management, LLC | 0.00% | Add +2.8% | 418,016 | $15.8M |
| Balyasny Asset Management L.P. | 0.04% | New | 403,003 | $15.3M |
| CIBC Asset Management Inc | 0.05% | Add +6.0% | 388,759 | $14.7M |
| Point72 Asset Management | 0.04% | Reduce -36.0% | 333,534 | $12.6M |
| Baker Bros. Advisors LP | 0.14% | No change | 331,533 | $12.6M |
| Franklin Resources Inc. | 0.00% | Reduce -19.4% | 314,127 | $11.9M |
| Verition Fund Management LLC | 0.04% | Reduce -57.0% | 199,657 | $7.6M |
| UBS Group AG | 0.00% | Add +60.4% | 192,909 | $7.3M |
| Velan Capital Investment Management LP | 7.21% | Reduce -38.3% | 185,000 | $7.0M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -36.5% | 177,264 | $6.7M |
| Woodline Partners LP | 0.04% | Add +1666.5% | 175,727 | $6.7M |
| 5AM Venture Management, LLC | 2.43% | No change | 170,000 | $6.4M |
| Silverarc Capital Management, LLC | 1.31% | Add +129.0% | 166,074 | $6.3M |
| Northern Trust Corp. | 0.00% | Reduce -1.4% | 165,183 | $6.3M |
| PFM Health Sciences, LP | 0.48% | Add +34.6% | 160,866 | $6.1M |
| Sofinnova Investments, Inc. | 0.45% | New | 157,640 | $6.0M |
| Alyeska Investment Group, L.P. | 0.02% | Reduce -33.9% | 150,000 | $5.7M |
| Ikarian Capital, LLC | 1.80% | New | 145,502 | $5.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -1.3% | 141,080 | $5.3M |
| Sphera Funds Management LTD. | 1.31% | Add +53.6% | 140,660 | $5.3M |
| Walleye Capital LLC | 0.06% | Add +47.0% | 131,756 | $5.0M |
| Sio Capital Management, LLC | 1.29% | New | 112,500 | $4.3M |
| Ally Bridge Group (NY) LLC | 3.26% | Add +112.5% | 95,582 | $3.6M |
| Aberdeen Group plc | 0.01% | Add +1658.4% | 87,903 | $3.3M |
| Acuta Capital Partners, LLC | 3.83% | Add +29.1% | 87,141 | $3.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +367.8% | 87,081 | $3.3M |
| Norges Bank | 0.00% | Reduce -29.2% | 84,200 | $3.2M |
| Tri Locum Partners LP | 1.63% | Add +124.5% | 83,659 | $3.2M |
| Pictet Asset Management Holding SA | 0.00% | Add +73.0% | 78,588 | $3.0M |
| First Turn Management, LLC | 0.55% | Add +57.6% | 71,775 | $2.7M |
| Millennium Management | 0.00% | Reduce -54.1% | 69,181 | $2.6M |
| 72 Investment Holdings, LLC | 7.02% | No change | 65,933 | $2.5M |
| Kennedy Capital Management LLC | 0.06% | New | 65,265 | $2.5M |
| Candriam S.C.A. | 0.02% | Reduce -46.0% | 63,671 | $2.4M |
| Citadel Advisors | 0.00% | Reduce -33.2% | 62,210 | $2.4M |
| Alliancebernstein L.P. | 0.00% | Reduce -35.0% | 51,116 | $1.9M |
| Wellington Management Group LLP | 0.00% | Reduce -20.6% | 50,776 | $1.9M |
| Boothbay Fund Management, LLC | 0.06% | New | 46,626 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.2% | 46,307 | $1.8M |
| Citigroup Inc. | 0.00% | Reduce -52.0% | 45,632 | $1.7M |
| Jacobs Levy Equity Management, Inc. | 0.01% | No change | 39,999 | $1.5M |
| ExodusPoint Capital Management, LP | 0.02% | New | 39,975 | $1.5M |
| HighVista Strategies LLC | 0.57% | Add +258.7% | 39,286 | $1.5M |
| TD Asset Management Inc | 0.00% | Reduce -29.8% | 37,138 | $1.4M |
| FMR LLC | 0.00% | Reduce -81.0% | 35,719 | $1.4M |
| Susquehanna International Group, LLP | 0.00% | Reduce -78.0% | 34,748 | $1.3M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -15.6% | 32,492 | $1.2M |
| Barclays PLC | 0.00% | Reduce -14.8% | 31,768 | $1.2M |
| Moody Aldrich Partners LLC | 0.24% | Reduce -1.5% | 30,221 | $1.1M |
| Rafferty Asset Management, LLC | 0.00% | Reduce -13.0% | 29,245 | $1.1M |
| Swiss National Bank | 0.00% | Add +3.8% | 27,100 | $1.0M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.02% | Add +1.1% | 26,793 | $1.0M |
| Rhumbline Advisers | 0.00% | Add +6.7% | 24,294 | $920K |
| Algert Global LLC | 0.02% | New | 21,490 | $814K |
| Atom Investors LP | 0.09% | New | 19,779 | $749K |
| B Group, Inc. | 0.63% | New | 19,000 | $720K |
| Two Sigma Investments, LP | 0.00% | Reduce -6.3% | 18,808 | $712K |
| Caption Management, LLC | 0.03% | New | 18,280 | $692K |
| PCG Wealth Advisors, LLC | 0.22% | Reduce -5.0% | 16,413 | $622K |
| California State Teachers Retirement System | 0.00% | Add +28.4% | 16,346 | $619K |
| Alps Advisors Inc. | 0.00% | Reduce -0.8% | 14,938 | $566K |
| State of Wisconsin Investment Board | 0.00% | Add +36.8% | 14,611 | $553K |
| Legal & General Group Plc | 0.00% | Reduce -0.2% | 14,409 | $546K |
| Deutsche Bank AG | 0.00% | Reduce -9.6% | 13,861 | $525K |
| Gsa Capital Partners LLP | 0.04% | Add +128.4% | 12,977 | $491K |
| D. E. Shaw & Co. | 0.00% | Reduce -74.6% | 12,208 | $462K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +5.2% | 11,708 | $444K |
| Invesco Ltd. | 0.00% | Reduce -86.6% | 11,678 | $442K |
| JPMorgan Chase & Co. | 0.00% | Add +18.4% | 11,479 | $435K |
| Group One Trading LLC | 0.02% | New | 10,927 | $414K |
| MetLife Investment Management, LLC | 0.00% | Reduce -0.7% | 10,597 | $401K |
| Hussman Strategic Advisors, Inc. | 0.10% | No change | 10,500 | $398K |
| XTX Topco Ltd | 0.02% | New | 10,043 | $380K |
| Nuveen, LLC | 0.00% | — | 14,762 | $377K |
| Jane Street Group, LLC | 0.00% | Reduce -74.5% | 9,489 | $359K |
| Intech Investment Management LLC | 0.00% | Add +38.8% | 8,798 | $333K |
| Wells Fargo & Company | 0.00% | Reduce -1.1% | 8,517 | $323K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 8,448 | $320K |
| LMR Partners LLP | 0.01% | New | 7,774 | $294K |
| Engineers Gate Manager LP | 0.00% | Add +97.6% | 7,606 | $288K |
| BNP Paribas Financial Markets | 0.00% | Add +247.8% | 7,451 | $282K |
| New York State Common Retirement Fund | 0.00% | Reduce -15.9% | 6,600 | $250K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | New | 6,250 | $237K |
| Profund Advisors LLC | 0.01% | Reduce -6.9% | 6,108 | $231K |
"% of holder's portfolio" is PRAX's weight in each manager's 13F, not the share of Praxis Precision Medicines I the manager owns.