Praxis Precision Medicines IPRAX
13F holders, Q1 2026 (March 31)291holders +41
72new positions
30sold out
2famous investors
$321.97avg. 13F price*
At the end of Q1 2026, 291 institutions reported holding Praxis Precision Medicines I (PRAX) in their 13F filings, up 41 from Q4 2025. 72 opened new positions and 30 sold out. The largest holders were Janus Henderson Group PLC ($1.1B), Orbis Allan Gray Ltd ($796.6M) and BlackRock, Inc. ($749.1M). 2 famous investors held it, including Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Praxis Precision Medicines I
- CUSIP
- 74006W207
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 72 | $75.0M |
| Exits | 30 | $358.2M |
All 13F filers, Q4 2025 → Q1 2026: 4,667,433 shares bought and 3,064,233 shares sold, net +1,603,200 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 291 holders
| Janus Henderson Group PLC | 0.53% | Add +6.8% | 3,458,863 | $1.1B |
| Orbis Allan Gray Ltd | 3.36% | Add +97.0% | 2,472,480 | $796.6M |
| BlackRock, Inc. | 0.01% | Add +11.9% | 2,324,929 | $749.1M |
| FMR LLC | 0.04% | Add +59.0% | 2,160,943 | $696.2M |
| Perceptive Advisors LLC | 13.00% | Add +2.0% | 2,035,986 | $656.0M |
| Baker Bros. Advisors LP | 3.24% | Add +55.6% | 1,753,198 | $564.9M |
| Vanguard Capital Management LLC | 0.01% | — | 1,221,944 | $393.7M |
| Deerfield Management Company, L.P. | 4.33% | Add +6.6% | 963,351 | $310.4M |
| Driehaus Capital Management LLC | 2.25% | Add +1.7% | 949,225 | $305.8M |
| Cormorant Asset Management, LP | 14.38% | Reduce -6.8% | 885,500 | $285.3M |
| State Street Corp. | 0.01% | Add +0.2% | 884,238 | $284.9M |
| Morgan Stanley | 0.02% | Reduce -6.3% | 833,491 | $268.5M |
| Adage Capital Partners Gp, L.L.C. | 0.41% | Reduce -15.5% | 815,739 | $262.8M |
| Vanguard Portfolio Management LLC | 0.01% | — | 756,748 | $243.8M |
| Goldman Sachs Group Inc. | 0.03% | Reduce -0.8% | 710,734 | $229.0M |
| Geode Capital Management, LLC | 0.01% | Add +15.7% | 650,904 | $209.8M |
| T. Rowe Price Associates Inc. | 0.02% | Reduce -19.7% | 630,852 | $203.3M |
| Bank of America Corp. | 0.01% | Add +2.3% | 534,604 | $172.2M |
| Ra Capital Management, L.P. | 1.28% | No change | 373,787 | $120.4M |
| Hood River Capital Management LLC | 1.16% | Add +23.9% | 358,618 | $115.5M |
| Vivo Capital, LLC | 9.08% | Add +3.0% | 338,895 | $109.2M |
| Soleus Capital Management, L.P. | 4.31% | Reduce -8.9% | 330,517 | $106.5M |
| Logos Global Management LP | 4.73% | Reduce -24.0% | 285,000 | $91.8M |
| Pictet Asset Management Holding SA | 0.10% | Add +19.1% | 286,644 | $91.4M |
| Franklin Resources Inc. | 0.02% | Reduce -22.4% | 276,123 | $89.0M |
| Northern Trust Corp. | 0.01% | Add +18.5% | 227,934 | $73.4M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +8.7% | 215,447 | $69.4M |
| Woodline Partners LP | 0.24% | Add +89.7% | 200,013 | $64.4M |
| T. Rowe Price Investment Management, Inc. | 0.04% | Reduce -36.6% | 175,237 | $56.5M |
| Wellington Management Group LLP | 0.01% | Reduce -1.3% | 174,350 | $56.2M |
| Orbimed Advisors LLC | 1.26% | Add +82.5% | 172,500 | $55.6M |
| Aberdeen Group plc | 0.09% | Add +27.8% | 172,484 | $55.6M |
| Affinity Asset Advisors, LLC | 3.28% | Reduce -8.1% | 170,000 | $54.8M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 169,902 | $54.7M |
| BNP Paribas Financial Markets | 0.03% | Add +2993.0% | 143,082 | $46.1M |
| American Century Companies Inc. | 0.02% | Add +70.2% | 128,254 | $41.3M |
| Qube Research & Technologies Ltd | 0.06% | Reduce -24.1% | 128,228 | $41.3M |
| ArrowMark Colorado Holdings LLC | 1.01% | Add +292.8% | 117,851 | $38.0M |
| UBS Group AG | 0.01% | Add +21.6% | 108,446 | $34.9M |
| Velan Capital Investment Management LP | 20.34% | No change | 100,781 | $32.5M |
| Bank of New York Mellon Corp | 0.01% | Add +11.8% | 87,047 | $28.0M |
| Acuta Capital Partners, LLC | 19.46% | Add +2.3% | 84,901 | $27.4M |
| MetLife Investment Management, LLC | 0.13% | Add +551.4% | 80,930 | $26.1M |
| Alyeska Investment Group, L.P. | 0.07% | Reduce -3.0% | 72,178 | $23.3M |
| Nuveen, LLC | 0.01% | Add +44.2% | 72,043 | $23.2M |
| Ikarian Capital, LLC | 3.30% | Reduce -17.3% | 71,581 | $23.1M |
| Silverarc Capital Management, LLC | 2.72% | Reduce -13.2% | 71,552 | $23.1M |
| JPMorgan Chase & Co. | 0.00% | Add +45.0% | 80,180 | $22.2M |
| Ensign Peak Advisors, Inc | 0.04% | Add +6.4% | 68,383 | $22.0M |
| 72 Investment Holdings, LLC | 42.83% | No change | 65,933 | $21.2M |
| Sofinnova Investments, Inc. | 1.03% | Reduce -49.4% | 63,680 | $20.5M |
| Candriam S.C.A. | 0.11% | Reduce -42.5% | 63,628 | $20.5M |
| Invesco Ltd. | 0.00% | Reduce -20.4% | 61,397 | $19.8M |
| AQR Capital Management | 0.01% | Add +103.5% | 58,656 | $18.9M |
| Deutsche Bank AG | 0.01% | Add +13.7% | 57,779 | $18.6M |
| Stempoint Capital LP | 3.48% | Add +167.1% | 56,267 | $18.1M |
| Frontier Capital Management Co. LLC | 0.18% | New | 53,365 | $17.2M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.03% | Add +26.9% | 47,432 | $15.3M |
| Swiss National Bank | 0.01% | Add +15.3% | 46,700 | $15.0M |
| Boxer Capital Management, LLC | 1.97% | No change | 46,457 | $15.0M |
| Exome Asset Management LLC | 8.62% | Reduce -21.8% | 45,469 | $14.6M |
| Marshall Wace, LLP | 0.02% | Reduce -34.8% | 45,149 | $14.5M |
| KVP Capital Advisors, LP | 10.32% | No change | 42,900 | $13.8M |
| First Turn Management, LLC | 1.53% | Add +18.7% | 42,441 | $13.7M |
| California Public Employees Retirement System | 0.01% | New | 42,163 | $13.6M |
| Canada Pension Plan Investment Board | 0.01% | Reduce -42.4% | 40,130 | $12.9M |
| Integral Health Asset Management, LLC | 0.68% | No change | 40,000 | $12.9M |
| Eventide Asset Management, LLC | 0.21% | Reduce -42.4% | 38,640 | $12.4M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +8.1% | 38,145 | $12.3M |
| SummitTX Capital, L.P. | 0.38% | Reduce -11.5% | 36,838 | $11.9M |
| PFM Health Sciences, LP | 1.22% | Add +13.7% | 35,438 | $11.4M |
| TD Asset Management Inc | 0.01% | Reduce -23.8% | 35,146 | $11.3M |
| Burkehill Global Management, LP | 0.59% | Add +40.0% | 35,000 | $11.3M |
| First Trust Advisors LP | 0.01% | Reduce -62.4% | 33,335 | $10.7M |
| B Group, Inc. | 7.94% | No change | 33,237 | $10.7M |
| Rhumbline Advisers | 0.01% | Add +16.1% | 32,879 | $10.6M |
| Ally Bridge Group (NY) LLC | 10.50% | Add +65.0% | 32,810 | $10.6M |
| Ameriprise Financial Inc. | 0.00% | Add +37.4% | 31,220 | $10.1M |
| Dimensional Fund Advisors LP | 0.00% | Add +32.4% | 31,161 | $10.0M |
| Prudential Financial Inc. | 0.01% | Add +105.3% | 30,510 | $9.8M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -9.6% | 30,093 | $9.7M |
| Lord, Abbett & Co. LLC | 0.03% | Reduce -3.7% | 29,619 | $9.5M |
| Sei Investments Co. | 0.01% | Add +86.9% | 29,525 | $9.5M |
| Voya Investment Management LLC | 0.01% | Add +106.0% | 28,134 | $9.1M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.01% | Add +8.6% | 27,744 | $8.9M |
| California State Teachers Retirement System | 0.01% | Add +39.7% | 27,477 | $8.9M |
| HighVista Strategies LLC | 2.34% | Add +1.9% | 26,323 | $8.5M |
| Neuberger Berman Group LLC | 0.01% | Add +1.1% | 25,960 | $8.4M |
| Alliancebernstein L.P. | 0.00% | Add +10.5% | 27,700 | $8.2M |
| University of Wisconsin Foundation | 7.21% | New | 25,215 | $8.1M |
| Congress Asset Management Co. | 0.06% | Reduce -20.5% | 24,839 | $8.0M |
| Susquehanna Portfolio Strategies, LLC | 0.11% | No change | 23,251 | $7.5M |
| Russell Investments Group, Ltd. | 0.01% | Add +12.1% | 23,112 | $7.4M |
| Ishara Investments LP | 7.34% | Reduce -43.6% | 22,550 | $7.3M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.01% | — | 22,000 | $7.1M |
| Moody Aldrich Partners LLC | 1.26% | Reduce -48.0% | 21,688 | $7.0M |
| Atom Investors LP | 0.49% | Add +28.6% | 21,196 | $6.8M |
| Informed Momentum Co LLC | 0.71% | Reduce -9.3% | 18,995 | $6.1M |
| Legal & General Group Plc | 0.00% | Add +2.8% | 18,482 | $6.0M |
| Two Sigma Investments, LP | 0.00% | Reduce -23.8% | 17,598 | $5.7M |
"% of holder's portfolio" is PRAX's weight in each manager's 13F, not the share of Praxis Precision Medicines I the manager owns.