Prime MedicinePRME
13F holders, Q4 2024 (December 31)132holders +16
27new positions
17sold out
4famous investors
$2.92avg. 13F price*
At the end of Q4 2024, 132 institutions reported holding Prime Medicine Inc. (PRME) in their 13F filings, up 16 from Q3 2024. 27 opened new positions and 17 sold out. The largest holders were Alphabet Inc. ($44.0M), ARK Investment Management ($15.0M) and BlackRock, Inc. ($13.2M). 4 famous investors held it, including Cathie Wood (0.1% of ARK Investment Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Prime Medicine Inc.
- CUSIP
- 74168J101
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $1.9M |
| Exits | 17 | $13.2M |
All 13F filers, Q3 2024 → Q4 2024: 2,638,330 shares bought and 7,187,793 shares sold, net −4,549,463 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 132 holders
| Alphabet Inc. | 2.56% | No change | 15,062,498 | $44.0M |
| ARK Investment Management | 0.13% | Reduce -9.0% | 5,150,233 | $15.0M |
| BlackRock, Inc. | 0.00% | Reduce -14.1% | 4,524,784 | $13.2M |
| T. Rowe Price Investment Management, Inc. | 0.01% | Add +4.5% | 3,977,828 | $11.6M |
| FMR LLC | 0.00% | Add +1.6% | 3,802,028 | $11.1M |
| Vanguard Group Inc. | 0.00% | Reduce -25.3% | 3,655,317 | $10.7M |
| Amova Asset Management Americas, Inc. | 0.10% | Reduce -2.9% | 3,090,180 | $9.0M |
| Sumitomo Mitsui Trust Group, Inc. | 0.01% | Reduce -3.1% | 3,090,180 | $9.0M |
| Redmile Group, LLC | 0.42% | No change | 2,074,350 | $6.1M |
| Millennium Management | 0.00% | Reduce -14.7% | 1,874,571 | $5.5M |
| MWG Management Ltd. | 7.04% | No change | 1,792,210 | $5.2M |
| T. Rowe Price Associates Inc. | 0.00% | Add +2.5% | 1,584,476 | $4.6M |
| Geode Capital Management, LLC | 0.00% | Add +7.9% | 1,467,606 | $4.3M |
| State Street Corp. | 0.00% | Add +0.6% | 1,154,181 | $3.4M |
| Baker Bros. Advisors LP | 0.03% | No change | 1,028,466 | $3.0M |
| Westwood Holdings Group Inc. | 0.02% | Add +96.5% | 883,129 | $2.6M |
| Greenwich Wealth Management LLC | 0.16% | Add +5.6% | 774,001 | $2.3M |
| Farallon Capital Management, L.L.C. | 0.01% | No change | 750,000 | $2.2M |
| EcoR1 Capital, LLC | 0.08% | No change | 700,000 | $2.0M |
| Northern Trust Corp. | 0.00% | Add +3.9% | 544,937 | $1.6M |
| Moore Capital Management, LP | 0.03% | No change | 500,000 | $1.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.4% | 484,591 | $1.4M |
| Bank of America Corp. | 0.00% | Reduce -11.2% | 430,613 | $1.3M |
| Goldman Sachs Group Inc. | 0.00% | Add +91.7% | 421,898 | $1.2M |
| Samsara Biocapital, LLC | 0.16% | Reduce -25.0% | 405,228 | $1.2M |
| Walleye Capital LLC | 0.01% | Add +272.5% | 403,739 | $1.2M |
| Nuveen Asset Management, LLC | 0.00% | No change | 392,443 | $1.1M |
| Casdin Capital, LLC | 0.07% | No change | 367,175 | $1.1M |
| Bollard Group LLC | 0.03% | No change | 361,136 | $1.1M |
| Morgan Stanley | 0.00% | Add +3.6% | 311,276 | $909K |
| UBS Group AG | 0.00% | Add +523.0% | 218,186 | $637K |
| Chelsea Counsel Co. | 0.28% | Add +137.4% | 186,780 | $545K |
| Two Sigma Investments, LP | 0.00% | Reduce -47.8% | 166,199 | $485K |
| Vestmark Advisory Solutions, Inc. | 0.02% | Add +23.8% | 111,465 | $460K |
| Susquehanna Fundamental Investments, LLC | 0.01% | — | 144,719 | $423K |
| ExodusPoint Capital Management, LP | 0.00% | New | 131,732 | $385K |
| Bank of New York Mellon Corp | 0.00% | Reduce -0.1% | 129,514 | $378K |
| FIL Ltd | 0.00% | Reduce -6.8% | 121,017 | $353K |
| Verition Fund Management LLC | 0.00% | Add +168.6% | 103,545 | $302K |
| Jane Street Group, LLC | 0.00% | Add +76.8% | 101,758 | $297K |
| Barclays PLC | 0.00% | Add +15.3% | 97,621 | $285K |
| Wells Fargo & Company | 0.00% | Reduce -43.9% | 96,181 | $281K |
| Deutsche Bank AG | 0.00% | Reduce -29.6% | 80,835 | $236K |
| Alliancebernstein L.P. | 0.00% | No change | 76,000 | $222K |
| Levin Capital Strategies, L.P. | 0.02% | Add +150.0% | 75,000 | $219K |
| Rhumbline Advisers | 0.00% | Add +2.7% | 71,956 | $210K |
| Aristides Capital LLC | 0.06% | New | 70,500 | $206K |
| Point72 Asset Management | 0.00% | New | 68,528 | $200K |
| Green Alpha Advisors, LLC | 0.15% | New | 64,406 | $188K |
| IQ EQ FUND MANAGEMENT (IRELAND) Ltd | 0.02% | Add +115.9% | 60,685 | $177K |
| SG Americas Securities, LLC | 0.00% | Add +28.2% | 60,229 | $176K |
| Sculptor Capital LP | 0.00% | New | 50,700 | $148K |
| Citigroup Inc. | 0.00% | Reduce -1.3% | 47,431 | $138K |
| TD Asset Management Inc | 0.00% | No change | 46,434 | $136K |
| Two Sigma Advisers, LP | 0.00% | Reduce -64.0% | 43,200 | $126K |
| Susquehanna International Group, LLP | 0.00% | Reduce -67.8% | 37,052 | $108K |
| JPMorgan Chase & Co. | 0.00% | Reduce -4.7% | 35,640 | $104K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.4% | 32,499 | $95K |
| Crestwood Advisors Group, LLC | 0.00% | New | 31,687 | $93K |
| Intech Investment Management LLC | 0.00% | Add +115.6% | 30,404 | $89K |
| PEAK6 LLC | 0.00% | — | 30,013 | $88K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 28,197 | $82K |
| China Universal Asset Management Co., Ltd. | 0.01% | Add +20.5% | 27,811 | $81K |
| Creative Planning | 0.00% | New | 27,623 | $81K |
| MetLife Investment Management, LLC | 0.00% | Reduce -26.7% | 25,031 | $73K |
| Prime Capital Investment Advisors, LLC | 0.00% | New | 23,955 | $70K |
| Virtus Advisers, LLC | 0.03% | Add +102.4% | 23,618 | $69K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.8% | 23,592 | $69K |
| Avanza Fonder AB | 0.00% | — | 22,480 | $66K |
| ProShare Advisors LLC | 0.00% | Add +24.6% | 22,186 | $65K |
| Benjamin Edwards Inc. | 0.00% | Reduce -5.5% | 21,921 | $64K |
| HighTower Advisors, LLC | 0.00% | Reduce -0.4% | 21,590 | $63K |
| HRT Financial LP | 0.00% | New | 21,695 | $63K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -24.0% | 21,557 | $63K |
| Sherbrooke Park Advisers LLC | 0.02% | New | 20,441 | $60K |
| BNP Paribas Financial Markets | 0.00% | New | 20,096 | $59K |
| Cibc World Market Inc. | 0.00% | Add +86.1% | 19,023 | $56K |
| Voya Investment Management LLC | 0.00% | Reduce -5.3% | 18,173 | $53K |
| Impact Partnership Wealth, LLC | 0.01% | New | 17,274 | $50K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 17,092 | $50K |
| Balyasny Asset Management L.P. | 0.00% | New | 16,342 | $48K |
| Clarius Group, LLC | 0.00% | No change | 16,080 | $47K |
| AQR Capital Management | 0.00% | New | 16,046 | $47K |
| Gsa Capital Partners LLP | 0.00% | Reduce -84.5% | 15,311 | $45K |
| Axq Capital, LP | 0.02% | New | 15,363 | $45K |
| Invesco Ltd. | 0.00% | Add +7.5% | 15,071 | $44K |
| XTX Topco Ltd | 0.00% | New | 14,466 | $42K |
| Nisa Investment Advisors, LLC | 0.00% | Add +11474.3% | 12,616 | $37K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 12,378 | $36K |
| Oppenheimer & Co. Inc. | 0.00% | Reduce -32.3% | 12,106 | $35K |
| American Century Companies Inc. | 0.00% | New | 11,426 | $33K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 11,420 | $33K |
| Pathstone Holdings, LLC | 0.00% | Reduce -21.3% | 11,311 | $33K |
| New York State Common Retirement Fund | 0.00% | No change | 8,434 | $25K |
| Legal & General Group Plc | 0.00% | No change | 6,279 | $18K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.7% | 4,371 | $13K |
| California State Teachers Retirement System | 0.00% | No change | 4,110 | $12K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 3,901 | $11K |
| GF Fund Management Co. LTD. | 0.00% | — | 2,700 | $8K |
| Cwm, LLC | 0.00% | Add +10954.5% | 2,432 | $7K |
| R Squared Ltd | 0.01% | — | 2,230 | $7K |
| Brooklyn Investment Group | 0.00% | New | 1,894 | $6K |
| Signaturefd, LLC | 0.00% | Add +17.2% | 1,653 | $5K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -82.6% | 1,397 | $4K |
| Simplex Trading, LLC | 0.00% | New | 1,458 | $4K |
| Amalgamated Bank | 0.00% | No change | 1,347 | $4K |
| SBI Securities Co., Ltd. | 0.00% | — | 1,205 | $4K |
| First Horizon Advisors, Inc. | 0.00% | No change | 1,109 | $3K |
| Comerica Bank | 0.00% | Add +240.6% | 1,073 | $3K |
| Royal Bank of Canada | 0.00% | Reduce -89.1% | 1,162 | $3K |
| Quadrant Capital Group LLC | 0.00% | Reduce -13.8% | 833 | $2K |
| Fairman Group, LLC | 0.00% | No change | 500 | $1K |
| National Bank of Canada | 0.00% | Reduce -91.2% | 400 | $1K |
| Russell Investments Group, Ltd. | 0.00% | Add +646.1% | 388 | $1K |
| Osaic Holdings, Inc. | 0.00% | Reduce -96.1% | 388 | $1K |
| Daiwa Securities Group Inc. | 0.00% | No change | 398 | $1K |
| Point72 (DIFC) Ltd | 0.00% | New | 309 | $902 |
| Rothschild Investment LLC | 0.00% | New | 280 | $818 |
| Principal Securities, Inc. | 0.00% | No change | 280 | $818 |
| Raffa Wealth Management, LLC | 0.00% | New | 250 | $730 |
| US Bancorp \de | 0.00% | New | 202 | $590 |
| Allworth Financial LP | 0.00% | New | 141 | $449 |
| PNC Financial Services Group, Inc. | 0.00% | Add +421.4% | 146 | $426 |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 104 | $304 |
| Catherine Avery Investment Management LLC | 0.00% | — | 67 | $196 |
| Sterling Capital Management LLC | 0.00% | No change | 58 | $169 |
| Farther Finance Advisors, LLC | 0.00% | No change | 26 | $76 |
| IFP Advisors, Inc | 0.00% | New | 24 | $70 |
| Federated Hermes, Inc. | 0.00% | Add +50.0% | 6 | $18 |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -94.3% | 6 | $18 |
| Lazard Asset Management LLC | 0.00% | No change | 26 | $0 |
| Covestor Ltd | 0.00% | Add +7.7% | 14 | $0 |
"% of holder's portfolio" is PRME's weight in each manager's 13F, not the share of Prime Medicine Inc. the manager owns.