Q32 BioQTTB
13F holders, Q1 2026 (March 31)At the end of Q1 2026, 53 institutions reported holding Q32 Bio Inc. (QTTB) in their 13F filings, up 1 from Q4 2025. 8 opened new positions and 8 sold out. The largest holders were Orbimed Advisors LLC ($14.5M), Atlas Venture Life Science Advisors, LLC ($13.4M) and Opaleye Management Inc. ($8.1M). 2 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Q32 Bio Inc.
- CUSIP
- 746964105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 8 | $3.3M |
| Exits | 8 | $544K |
All 13F filers, Q4 2025 → Q1 2026: 1,916,030 shares bought and 566,801 shares sold, net +1,349,229 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 53 holders
| Orbimed Advisors LLC | 0.33% | No change | 2,252,987 | $14.5M |
| Atlas Venture Life Science Advisors, LLC | 1.70% | No change | 2,092,106 | $13.4M |
| Opaleye Management Inc. | 1.06% | Add +488.8% | 1,256,228 | $8.1M |
| Carlyle Group Inc. | 0.07% | No change | 1,102,741 | $7.1M |
| ARCH Venture Management, LLC | 0.30% | No change | 320,482 | $2.1M |
| Acorn Capital Advisors, LLC | 0.57% | Reduce -36.1% | 315,052 | $2.0M |
| Vanguard Capital Management LLC | 0.00% | — | 306,401 | $2.0M |
| Mackenzie Financial Corp. | 0.00% | New | 246,304 | $1.6M |
| Sanofi | 0.47% | No change | 244,083 | $1.6M |
| Renaissance Technologies | 0.00% | Add +107.8% | 206,915 | $1.3M |
| Acadian Asset Management LLC | 0.00% | Add +256.8% | 172,586 | $1.1M |
| Monimus Capital Management, LP | 0.24% | New | 134,310 | $862K |
| Geode Capital Management, LLC | 0.00% | Add +11.3% | 118,152 | $759K |
| Pfizer Inc | 0.31% | Reduce -63.4% | 101,618 | $737K |
| BlackRock, Inc. | 0.00% | Add +43.7% | 86,147 | $553K |
| Jane Street Group, LLC | 0.00% | Add +158.5% | 65,599 | $421K |
| Marshall Wace, LLP | 0.00% | New | 52,440 | $337K |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 49,995 | $321K |
| Two Sigma Investments, LP | 0.00% | Reduce -9.6% | 42,346 | $272K |
| State Street Corp. | 0.00% | Add +95.5% | 41,514 | $267K |
| Cambridge Investment Research Advisors, Inc. | 0.00% | New | 35,025 | $225K |
| ADAR1 Capital Management, LLC | 0.01% | Add +75.0% | 35,000 | $225K |
| Affinity Asset Advisors, LLC | 0.01% | No change | 27,777 | $178K |
| Northern Trust Corp. | 0.00% | No change | 25,033 | $161K |
| Cetera Investment Advisers | 0.00% | New | 20,695 | $133K |
| American Century Companies Inc. | 0.00% | New | 18,770 | $121K |
| Citadel Advisors | 0.00% | Reduce -66.2% | 15,481 | $99K |
| Bridgeway Capital Management, LLC | 0.00% | New | 12,613 | $81K |
| Morgan Stanley | 0.00% | Add +74.5% | 9,560 | $61K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 4,640 | $30K |
| FMR LLC | 0.00% | Add +1.1% | 3,400 | $22K |
| Royal Bank of Canada | 0.00% | Add +1067.7% | 2,744 | $18K |
| Federated Hermes, Inc. | 0.00% | No change | 2,273 | $15K |
| Vanguard Global Advisers, LLC | 0.00% | — | 1,915 | $12K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +91.7% | 1,871 | $12K |
| Arax Advisory Partners | 0.00% | Add +3.3% | 1,148 | $7K |
| Rockefeller Capital Management L.P. | 0.00% | No change | 577 | $4K |
| Jones Financial Companies LLLP | 0.00% | No change | 500 | $4K |
| Russell Investments Group, Ltd. | 0.00% | No change | 454 | $3K |
| BNP Paribas Financial Markets | 0.00% | Reduce -1.6% | 303 | $2K |
| UBS Group AG | 0.00% | Reduce -98.0% | 270 | $2K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 166 | $1K |
| Osaic Holdings, Inc. | 0.00% | Reduce -6.1% | 124 | $796 |
| Northwestern Mutual Wealth Management Co. | 0.00% | Add +270.0% | 111 | $713 |
| SBI Securities Co., Ltd. | 0.00% | Reduce -33.8% | 104 | $668 |
| Allworth Financial LP | 0.00% | No change | 98 | $630 |
| Wells Fargo & Company | 0.00% | New | 84 | $539 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 70 | $446 |
| Cwm, LLC | 0.00% | Reduce -27.8% | 39 | $250 |
| Group One Trading LLC | 0.00% | No change | 34 | $218 |
| Harbour Investments, Inc. | 0.00% | No change | 11 | $71 |
| AdvisorNet Financial, Inc | 0.00% | No change | 2 | $13 |
| Danske Bank A/S | 0.00% | No change | 1 | $6 |
"% of holder's portfolio" is QTTB's weight in each manager's 13F, not the share of Q32 Bio Inc. the manager owns.