Sana BiotechnologySANA
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 203 institutions reported holding Sana Biotechnology Inc. (SANA) in their 13F filings, up 25 from Q3 2025. 41 opened new positions and 21 sold out. The largest holders were FMR LLC ($152.3M), Flagship Pioneering, LLC ($101.8M) and BlackRock, Inc. ($57.9M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Sana Biotechnology Inc.
- CUSIP
- 799566104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $13.0M |
| Exits | 21 | $4.8M |
All 13F filers, Q3 2025 → Q4 2025: 15,686,659 shares bought and 20,219,553 shares sold, net −4,532,894 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 203 holders
| FMR LLC | 0.01% | Reduce 0.0% | 37,430,284 | $152.3M |
| Flagship Pioneering, LLC | 31.40% | No change | 25,001,856 | $101.8M |
| BlackRock, Inc. | 0.00% | Add +26.7% | 14,223,527 | $57.9M |
| Vanguard Group Inc. | 0.00% | Add +14.5% | 10,455,195 | $42.6M |
| Canada Pension Plan Investment Board | 0.03% | Add +0.7% | 10,242,100 | $41.7M |
| State Street Corp. | 0.00% | Add +20.6% | 8,054,841 | $32.8M |
| Baillie Gifford & Co. | 0.02% | Reduce -42.2% | 6,609,065 | $26.9M |
| Geode Capital Management, LLC | 0.00% | Add +20.3% | 4,118,138 | $16.8M |
| Marex Group Ltd | 0.16% | Reduce -2.4% | 3,732,780 | $15.2M |
| Integral Health Asset Management, LLC | 0.62% | Add +50.0% | 3,000,000 | $12.2M |
| Alphabet Inc. | 0.44% | No change | 2,812,500 | $11.4M |
| Renaissance Technologies | 0.01% | Reduce -15.1% | 1,691,116 | $6.9M |
| Balyasny Asset Management L.P. | 0.01% | New | 1,679,130 | $6.8M |
| Two Sigma Investments, LP | 0.01% | Add +158.9% | 1,579,705 | $6.4M |
| Goldman Sachs Group Inc. | 0.00% | Add +118.2% | 1,488,377 | $6.1M |
| Northern Trust Corp. | 0.00% | Add +6.8% | 1,407,699 | $5.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +10.0% | 1,399,335 | $5.7M |
| Woodline Partners LP | 0.02% | Reduce -4.4% | 1,317,641 | $5.4M |
| Morgan Stanley | 0.00% | Add +46.6% | 1,285,045 | $5.2M |
| Crestline Management, L.P. | 9.32% | Reduce -33.0% | 1,220,937 | $5.0M |
| Bank of America Corp. | 0.00% | Add +29.3% | 1,186,251 | $4.8M |
| UBS Group AG | 0.00% | Reduce -18.1% | 1,182,958 | $4.8M |
| AQR Capital Management | 0.00% | Reduce -4.0% | 1,134,324 | $4.6M |
| Omega Fund Management, LLC | 1.20% | No change | 843,750 | $3.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -61.8% | 815,455 | $3.3M |
| T. Rowe Price Associates Inc. | 0.00% | Add +424.6% | 766,487 | $3.1M |
| Great Point Partners LLC | 0.92% | No change | 700,000 | $2.8M |
| ArrowMark Colorado Holdings LLC | 0.06% | No change | 685,125 | $2.8M |
| Jane Street Group, LLC | 0.00% | Add +190.0% | 668,884 | $2.7M |
| Corient Private Wealth LP | 0.00% | Reduce -21.9% | 638,367 | $2.6M |
| Millennium Management | 0.00% | Reduce -61.5% | 623,242 | $2.5M |
| Deutsche Bank AG | 0.00% | Add +3.5% | 562,312 | $2.3M |
| Invesco Ltd. | 0.00% | Add +24.1% | 561,835 | $2.3M |
| Susquehanna International Group, LLP | 0.00% | Add +9.0% | 559,750 | $2.3M |
| Barclays PLC | 0.00% | Reduce -3.0% | 509,889 | $2.1M |
| Bank of New York Mellon Corp | 0.00% | Add +12.7% | 457,226 | $1.9M |
| Swiss National Bank | 0.00% | Add +28.0% | 335,800 | $1.4M |
| Squarepoint Ops LLC | 0.00% | Add +49.2% | 331,741 | $1.4M |
| Nuveen, LLC | 0.00% | Add +7.0% | 325,212 | $1.3M |
| Baker Bros. Advisors LP | 0.01% | Reduce -84.7% | 310,483 | $1.3M |
| Private Advisor Group, LLC | 0.01% | New | 309,399 | $1.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 112,300 | $1.2M |
| Rafferty Asset Management, LLC | 0.00% | Add +2.3% | 274,162 | $1.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +70.9% | 240,414 | $978K |
| Ieq Capital, LLC | 0.00% | Reduce -1.3% | 236,692 | $963K |
| Two Sigma Advisers, LP | 0.00% | New | 221,671 | $902K |
| Wells Fargo & Company | 0.00% | Add +79.6% | 191,081 | $778K |
| Rhumbline Advisers | 0.00% | Reduce -3.2% | 189,412 | $771K |
| Alliancebernstein L.P. | 0.00% | Reduce -5.0% | 186,945 | $761K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | No change | 167,503 | $682K |
| Clarius Group, LLC | 0.04% | Reduce -21.9% | 166,065 | $676K |
| California State Teachers Retirement System | 0.00% | Add +28.1% | 164,791 | $671K |
| Voya Investment Management LLC | 0.00% | Add +554.1% | 163,536 | $666K |
| Citigroup Inc. | 0.00% | Add +82.7% | 154,764 | $630K |
| Legal & General Group Plc | 0.00% | Add +16.8% | 151,018 | $615K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -82.9% | 133,078 | $542K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -21.1% | 130,291 | $530K |
| State of Wisconsin Investment Board | 0.00% | Reduce -35.0% | 128,856 | $524K |
| Palumbo Wealth Management LLC | 0.12% | Add +8.7% | 120,983 | $492K |
| Virtu Financial LLC | 0.02% | Add +189.4% | 119,312 | $486K |
| XTX Topco Ltd | 0.01% | Add +9.9% | 117,376 | $478K |
| Profund Advisors LLC | 0.01% | Add +76.8% | 102,046 | $415K |
| SG Americas Securities, LLC | 0.00% | Reduce -2.0% | 98,287 | $400K |
| Gilder Gagnon Howe & Co. LLC | 0.00% | Add +2.8% | 94,072 | $383K |
| MetLife Investment Management, LLC | 0.00% | Add +17.9% | 93,126 | $379K |
| HSBC Holdings PLC | 0.00% | Add +20.2% | 94,064 | $375K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +93.6% | 91,975 | $375K |
| Marshall Wace, LLP | 0.00% | New | 88,788 | $361K |
| Cwm, LLC | 0.00% | Reduce -0.0% | 85,106 | $346K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +66.7% | 82,393 | $335K |
| SCS Capital Management LLC | 0.00% | Reduce -0.1% | 81,250 | $331K |
| TD Asset Management Inc | 0.00% | New | 80,600 | $328K |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.00% | New | 77,350 | $315K |
| Brevan Howard Capital Management LP | 0.01% | New | 70,607 | $287K |
| Franklin Resources Inc. | 0.00% | Reduce -25.4% | 69,401 | $282K |
| VARCOV Co. | 0.10% | — | 64,907 | $264K |
| NewEdge Advisors, LLC | 0.00% | Reduce -34.0% | 64,399 | $262K |
| D. E. Shaw & Co. | 0.00% | New | 60,900 | $248K |
| Creative Planning | 0.00% | Add +12.4% | 60,899 | $248K |
| Quinn Opportunity Partners LLC | 0.01% | Reduce -50.0% | 60,100 | $245K |
| Algert Global LLC | 0.00% | New | 60,010 | $244K |
| Arax Advisory Partners | 0.01% | Reduce -64.3% | 59,028 | $240K |
| Janus Henderson Group PLC | 0.00% | No change | 58,189 | $237K |
| BIT Capital GmbH | 0.01% | New | 58,000 | $236K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +0.4% | 53,071 | $231K |
| Schonfeld Strategic Advisors LLC | 0.00% | New | 55,842 | $227K |
| Axq Capital, LP | 0.05% | Add +204.0% | 55,403 | $225K |
| Modus Advisors, LLC | 0.06% | New | 55,000 | $224K |
| Intech Investment Management LLC | 0.00% | Reduce -26.6% | 53,295 | $217K |
| Virtus Investment Advisers, LLC | 0.06% | Add +15.5% | 51,756 | $211K |
| Arizona State Retirement System | 0.00% | Add +18.4% | 47,342 | $193K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +20.5% | 44,245 | $180K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -4.3% | 43,404 | $177K |
| Cerity Partners LLC | 0.00% | Add +0.7% | 42,417 | $173K |
| Focus Partners Wealth | 0.00% | Add +37.3% | 42,156 | $172K |
| ProShare Advisors LLC | 0.00% | Add +31.5% | 42,126 | $171K |
| Pallas Capital Advisors LLC | 0.01% | No change | 39,627 | $161K |
| Raymond James Financial Inc. | 0.00% | New | 39,273 | $160K |
| New York State Common Retirement Fund | 0.00% | No change | 38,609 | $157K |
| Evoke Wealth, LLC | 0.00% | New | 38,569 | $157K |
| Group One Trading LLC | 0.00% | Add +30.1% | 37,444 | $152K |
| Teachers Retirement System of the State of Kentucky | 0.00% | Reduce -64.4% | 37,142 | $151K |
| KLP Kapitalforvaltning As | 0.00% | Add +28.4% | 36,200 | $147K |
| Gsa Capital Partners LLP | 0.01% | New | 32,222 | $131K |
| Atom Investors LP | 0.01% | New | 30,402 | $124K |
| Osaic Holdings, Inc. | 0.00% | Add +59.8% | 30,047 | $122K |
| Engineers Gate Manager LP | 0.00% | New | 28,304 | $115K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 26,678 | $109K |
| Merit Financial Group, LLC | 0.00% | Add +8.4% | 26,285 | $107K |
| Qube Research & Technologies Ltd | 0.00% | New | 26,224 | $107K |
| LPL Financial LLC | 0.00% | New | 25,675 | $104K |
| Teacher Retirement System of Texas | 0.00% | Reduce -23.4% | 24,772 | $101K |
| Viewpoint Capital Management LLC | 0.04% | No change | 23,545 | $96K |
| Hilton Capital Management, LLC | 0.01% | Reduce -67.1% | 22,075 | $90K |
| Hoey Investments, Inc. | 0.01% | No change | 22,000 | $90K |
| LaSalle St. Investment Advisors, LLC | 0.01% | Add +20.6% | 20,500 | $83K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -0.1% | 20,179 | $82K |
| T3 Companies, LLC | 0.11% | — | 20,000 | $81K |
| Stifel Financial Corp. | 0.00% | No change | 19,314 | $79K |
| Victory Capital Management Inc. | 0.00% | Add +14.8% | 19,098 | $78K |
| Polymer Capital Management (US) LLC | 0.01% | Add +32.5% | 18,285 | $74K |
| Pictet Asset Management Holding SA | 0.00% | New | 18,081 | $74K |
| Sei Investments Co. | 0.00% | No change | 17,668 | $72K |
| Cetera Investment Advisers | 0.00% | Add +42.8% | 17,431 | $71K |
| BNP Paribas Financial Markets | 0.00% | Reduce -74.3% | 17,315 | $70K |
| Quantinno Capital Management LP | 0.00% | New | 16,711 | $68K |
| Oxford Asset Management LLP | 0.02% | New | 16,684 | $68K |
| Syon Capital LLC | 0.00% | No change | 16,663 | $68K |
| Captrust Financial Advisors | 0.00% | Add +8.1% | 16,444 | $67K |
| Activest Wealth Management | 0.01% | New | 16,300 | $66K |
| Callan Family Office, LLC | 0.00% | New | 16,032 | $65K |
| Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors | 0.01% | Add +43.2% | 15,750 | $64K |
| Freestone Capital Holdings, LLC | 0.00% | New | 15,300 | $62K |
| Citadel Advisors | 0.00% | Reduce -99.8% | 13,541 | $55K |
| Ameritas Investment Partners, Inc. | 0.00% | Add +3.5% | 13,411 | $55K |
| Focus Partners Advisor Solutions, LLC | 0.00% | New | 13,407 | $55K |
| Xponance LLC | 0.00% | Add +25.6% | 13,068 | $53K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +29.4% | 12,944 | $53K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 12,043 | $49K |
| Mariner, LLC | 0.00% | Reduce -8.2% | 11,786 | $48K |
| Griffin Asset Management, Inc. | 0.01% | No change | 11,620 | $47K |
| Russell Investments Group, Ltd. | 0.00% | No change | 11,051 | $45K |
| Commonwealth Equity Services, LLC | 0.00% | New | 10,975 | $45K |
| Cibc World Markets Corp. | 0.00% | — | 10,930 | $44K |
| Neuberger Berman Group LLC | 0.00% | Reduce -3.9% | 10,746 | $44K |
| Foguth Wealth Management, LLC. | 0.01% | — | 10,402 | $44K |
| Lyell Wealth Management, LP | 0.00% | No change | 10,500 | $43K |
| Mercer Global Advisors Inc. | 0.00% | Add +1.4% | 10,222 | $42K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -7.4% | 10,101 | $41K |
| LRI Investments, LLC | 0.00% | New | 10,000 | $41K |
| Jacobi Capital Management LLC | 0.00% | New | 10,000 | $41K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 10,000 | $41K |
| Rockefeller Capital Management L.P. | 0.00% | Add +74.3% | 9,588 | $39K |
| Jones Financial Companies LLLP | 0.00% | Add +22.0% | 9,178 | $37K |
| Sterling Capital Management LLC | 0.00% | Add +4.2% | 8,549 | $35K |
| Redwood Park Advisors LLC | 0.02% | No change | 7,140 | $29K |
| Royal Bank of Canada | 0.00% | Reduce -98.8% | 6,947 | $28K |
| Simplex Trading, LLC | 0.00% | Reduce -91.7% | 5,996 | $24K |
| IFP Advisors, Inc | 0.00% | No change | 5,799 | $24K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -6.0% | 5,234 | $21K |
| Amalgamated Bank | 0.00% | Add +13.7% | 5,190 | $21K |
| Kestra Advisory Services, LLC | 0.00% | New | 5,150 | $21K |
| Atlantic Union Bankshares Corp | 0.00% | New | 5,012 | $20K |
| Washington Trust Advisors, Inc. | 0.00% | New | 5,000 | $20K |
| EFG International AG | 0.00% | — | 5,000 | $20K |
| Blue Trust, Inc. | 0.00% | Reduce -27.5% | 4,716 | $19K |
| Clearstead Advisors, LLC | 0.00% | Reduce -32.6% | 4,651 | $19K |
| Signaturefd, LLC | 0.00% | No change | 3,507 | $14K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 3,402 | $14K |
| Essential Partners LLC | 0.00% | Add +0.3% | 3,313 | $13K |
| Farther Finance Advisors, LLC | 0.00% | Add +24.6% | 2,491 | $10K |
| True Wealth Design, LLC | 0.00% | No change | 2,490 | $10K |
| International Assets Investment Management, LLC | 0.00% | New | 2,250 | $9K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +43.8% | 2,281 | $9K |
| Lanark Financial, Inc. | 0.00% | New | 2,100 | $9K |
| Hurley Capital, LLC | 0.00% | No change | 2,000 | $8K |
| Los Angeles Capital Management LLC | 0.00% | Reduce -93.6% | 1,494 | $7K |
| SBI Securities Co., Ltd. | 0.00% | Reduce -66.2% | 1,638 | $7K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -80.6% | 1,584 | $6K |
| Arlington Trust Co LLC | 0.00% | No change | 1,520 | $6K |
| Quadrant Capital Group LLC | 0.00% | No change | 1,480 | $6K |
| Quantbot Technologies LP | 0.00% | New | 1,287 | $5K |
| Allworth Financial LP | 0.00% | Add +15.4% | 1,167 | $5K |
| Triumph Capital Management | 0.00% | New | 1,000 | $4K |
| Global Retirement Partners, LLC | 0.00% | New | 1,000 | $4K |
| Federation des caisses Desjardins du Quebec | 0.00% | New | 1,000 | $4K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 975 | $4K |
| Daiwa Securities Group Inc. | 0.00% | No change | 767 | $3K |
| US Bancorp \de | 0.00% | No change | 585 | $2K |
| Smartleaf Asset Management LLC | 0.00% | No change | 532 | $2K |
| Optiver Holding B.V. | 0.00% | Reduce -72.3% | 509 | $2K |
| Mark Sheptoff Financial Planning, LLC | 0.00% | New | 500 | $2K |
| MAI Capital Management | 0.00% | No change | 474 | $2K |
| Rachor Investment Advisory Services, LLC | 0.00% | — | 369 | $2K |
| Rothschild Investment LLC | 0.00% | Add +4.5% | 324 | $1K |
| GAMMA Investing LLC | 0.00% | New | 255 | $1K |
| Torren Management, LLC | 0.00% | — | 191 | $777 |
| Parkside Financial Bank & Trust | 0.00% | No change | 186 | $758 |
| Creative Financial Designs Inc. | 0.00% | New | 100 | $407 |
| Bartlett & Co. Wealth Management LLC | 0.00% | No change | 100 | $407 |
| Sunbelt Securities, Inc. | 0.00% | No change | 22 | $90 |
| CIBC Private Wealth Group LLC | 0.00% | No change | 4 | $16 |
| Covestor Ltd | 0.00% | Reduce -3.9% | 25 | $0 |
"% of holder's portfolio" is SANA's weight in each manager's 13F, not the share of Sana Biotechnology Inc. the manager owns.