Sana BiotechnologySANA

13F holders, Q4 2025 (December 31)
203holders +25
41new positions
21sold out
5famous investors
$4.07avg. 13F price*

At the end of Q4 2025, 203 institutions reported holding Sana Biotechnology Inc. (SANA) in their 13F filings, up 25 from Q3 2025. 41 opened new positions and 21 sold out. The largest holders were FMR LLC ($152.3M), Flagship Pioneering, LLC ($101.8M) and BlackRock, Inc. ($57.9M). 5 famous investors held it, including Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio), Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Sana Biotechnology Inc.
CUSIP
799566104
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 154Q1 2024Q2 2024: 148Q2 2024Q3 2024: 155Q3 2024Q4 2024: 164Q4 2024Q1 2025: 161Q1 2025Q2 2025: 155Q2 2025Q3 2025: 178Q3 2025Q4 2025: 203Q4 2025Q1 2026: 203Q1 2026Q2 2026: 211Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions41$13.0M
Exits21$4.8M

All 13F filers, Q3 2025 → Q4 2025: 15,686,659 shares bought and 20,219,553 shares sold, net −4,532,894 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 203 holders

FMR LLC 0.01% Reduce 0.0% 37,430,284 $152.3M
Flagship Pioneering, LLC 31.40% No change 25,001,856 $101.8M
BlackRock, Inc. 0.00% Add +26.7% 14,223,527 $57.9M
Vanguard Group Inc. 0.00% Add +14.5% 10,455,195 $42.6M
Canada Pension Plan Investment Board 0.03% Add +0.7% 10,242,100 $41.7M
State Street Corp. 0.00% Add +20.6% 8,054,841 $32.8M
Baillie Gifford & Co. 0.02% Reduce -42.2% 6,609,065 $26.9M
Geode Capital Management, LLC 0.00% Add +20.3% 4,118,138 $16.8M
Marex Group Ltd 0.16% Reduce -2.4% 3,732,780 $15.2M
Integral Health Asset Management, LLC 0.62% Add +50.0% 3,000,000 $12.2M
Alphabet Inc. 0.44% No change 2,812,500 $11.4M
Renaissance Technologies 0.01% Reduce -15.1% 1,691,116 $6.9M
Balyasny Asset Management L.P. 0.01% New 1,679,130 $6.8M
Two Sigma Investments, LP 0.01% Add +158.9% 1,579,705 $6.4M
Goldman Sachs Group Inc. 0.00% Add +118.2% 1,488,377 $6.1M
Northern Trust Corp. 0.00% Add +6.8% 1,407,699 $5.7M
Charles Schwab Investment Management Inc. 0.00% Add +10.0% 1,399,335 $5.7M
Woodline Partners LP 0.02% Reduce -4.4% 1,317,641 $5.4M
Morgan Stanley 0.00% Add +46.6% 1,285,045 $5.2M
Crestline Management, L.P. 9.32% Reduce -33.0% 1,220,937 $5.0M
Bank of America Corp. 0.00% Add +29.3% 1,186,251 $4.8M
UBS Group AG 0.00% Reduce -18.1% 1,182,958 $4.8M
AQR Capital Management 0.00% Reduce -4.0% 1,134,324 $4.6M
Omega Fund Management, LLC 1.20% No change 843,750 $3.4M
JPMorgan Chase & Co. 0.00% Reduce -61.8% 815,455 $3.3M
T. Rowe Price Associates Inc. 0.00% Add +424.6% 766,487 $3.1M
Great Point Partners LLC 0.92% No change 700,000 $2.8M
ArrowMark Colorado Holdings LLC 0.06% No change 685,125 $2.8M
Jane Street Group, LLC 0.00% Add +190.0% 668,884 $2.7M
Corient Private Wealth LP 0.00% Reduce -21.9% 638,367 $2.6M
Millennium Management 0.00% Reduce -61.5% 623,242 $2.5M
Deutsche Bank AG 0.00% Add +3.5% 562,312 $2.3M
Invesco Ltd. 0.00% Add +24.1% 561,835 $2.3M
Susquehanna International Group, LLP 0.00% Add +9.0% 559,750 $2.3M
Barclays PLC 0.00% Reduce -3.0% 509,889 $2.1M
Bank of New York Mellon Corp 0.00% Add +12.7% 457,226 $1.9M
Swiss National Bank 0.00% Add +28.0% 335,800 $1.4M
Squarepoint Ops LLC 0.00% Add +49.2% 331,741 $1.4M
Nuveen, LLC 0.00% Add +7.0% 325,212 $1.3M
Baker Bros. Advisors LP 0.01% Reduce -84.7% 310,483 $1.3M
Private Advisor Group, LLC 0.01% New 309,399 $1.3M
DekaBank Deutsche Girozentrale 0.00% No change 112,300 $1.2M
Rafferty Asset Management, LLC 0.00% Add +2.3% 274,162 $1.1M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +70.9% 240,414 $978K
Ieq Capital, LLC 0.00% Reduce -1.3% 236,692 $963K
Two Sigma Advisers, LP 0.00% New 221,671 $902K
Wells Fargo & Company 0.00% Add +79.6% 191,081 $778K
Rhumbline Advisers 0.00% Reduce -3.2% 189,412 $771K
Alliancebernstein L.P. 0.00% Reduce -5.0% 186,945 $761K
Susquehanna Portfolio Strategies, LLC 0.01% No change 167,503 $682K
Clarius Group, LLC 0.04% Reduce -21.9% 166,065 $676K
California State Teachers Retirement System 0.00% Add +28.1% 164,791 $671K
Voya Investment Management LLC 0.00% Add +554.1% 163,536 $666K
Citigroup Inc. 0.00% Add +82.7% 154,764 $630K
Legal & General Group Plc 0.00% Add +16.8% 151,018 $615K
Dimensional Fund Advisors LP 0.00% Reduce -82.9% 133,078 $542K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -21.1% 130,291 $530K
State of Wisconsin Investment Board 0.00% Reduce -35.0% 128,856 $524K
Palumbo Wealth Management LLC 0.12% Add +8.7% 120,983 $492K
Virtu Financial LLC 0.02% Add +189.4% 119,312 $486K
XTX Topco Ltd 0.01% Add +9.9% 117,376 $478K
Profund Advisors LLC 0.01% Add +76.8% 102,046 $415K
SG Americas Securities, LLC 0.00% Reduce -2.0% 98,287 $400K
Gilder Gagnon Howe & Co. LLC 0.00% Add +2.8% 94,072 $383K
MetLife Investment Management, LLC 0.00% Add +17.9% 93,126 $379K
HSBC Holdings PLC 0.00% Add +20.2% 94,064 $375K
Manufacturers Life Insurance Company, The 0.00% Add +93.6% 91,975 $375K
Marshall Wace, LLP 0.00% New 88,788 $361K
Cwm, LLC 0.00% Reduce -0.0% 85,106 $346K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +66.7% 82,393 $335K
SCS Capital Management LLC 0.00% Reduce -0.1% 81,250 $331K
TD Asset Management Inc 0.00% New 80,600 $328K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% New 77,350 $315K
Brevan Howard Capital Management LP 0.01% New 70,607 $287K
Franklin Resources Inc. 0.00% Reduce -25.4% 69,401 $282K
VARCOV Co. 0.10% — 64,907 $264K
NewEdge Advisors, LLC 0.00% Reduce -34.0% 64,399 $262K
D. E. Shaw & Co. 0.00% New 60,900 $248K
Creative Planning 0.00% Add +12.4% 60,899 $248K
Quinn Opportunity Partners LLC 0.01% Reduce -50.0% 60,100 $245K
Algert Global LLC 0.00% New 60,010 $244K
Arax Advisory Partners 0.01% Reduce -64.3% 59,028 $240K
Janus Henderson Group PLC 0.00% No change 58,189 $237K
BIT Capital GmbH 0.01% New 58,000 $236K
Wealth Enhancement Advisory Services, LLC 0.00% Add +0.4% 53,071 $231K
Schonfeld Strategic Advisors LLC 0.00% New 55,842 $227K
Axq Capital, LP 0.05% Add +204.0% 55,403 $225K
Modus Advisors, LLC 0.06% New 55,000 $224K
Intech Investment Management LLC 0.00% Reduce -26.6% 53,295 $217K
Virtus Investment Advisers, LLC 0.06% Add +15.5% 51,756 $211K
Arizona State Retirement System 0.00% Add +18.4% 47,342 $193K
Police & Firemen's Retirement System of New Jersey 0.00% Add +20.5% 44,245 $180K
China Universal Asset Management Co., Ltd. 0.01% Reduce -4.3% 43,404 $177K
Cerity Partners LLC 0.00% Add +0.7% 42,417 $173K
Focus Partners Wealth 0.00% Add +37.3% 42,156 $172K
ProShare Advisors LLC 0.00% Add +31.5% 42,126 $171K
Pallas Capital Advisors LLC 0.01% No change 39,627 $161K
Raymond James Financial Inc. 0.00% New 39,273 $160K
New York State Common Retirement Fund 0.00% No change 38,609 $157K
Evoke Wealth, LLC 0.00% New 38,569 $157K
Group One Trading LLC 0.00% Add +30.1% 37,444 $152K
Teachers Retirement System of the State of Kentucky 0.00% Reduce -64.4% 37,142 $151K
KLP Kapitalforvaltning As 0.00% Add +28.4% 36,200 $147K
Gsa Capital Partners LLP 0.01% New 32,222 $131K
Atom Investors LP 0.01% New 30,402 $124K
Osaic Holdings, Inc. 0.00% Add +59.8% 30,047 $122K
Engineers Gate Manager LP 0.00% New 28,304 $115K
State Board of Administration of Florida Retirement System 0.00% No change 26,678 $109K
Merit Financial Group, LLC 0.00% Add +8.4% 26,285 $107K
Qube Research & Technologies Ltd 0.00% New 26,224 $107K
LPL Financial LLC 0.00% New 25,675 $104K
Teacher Retirement System of Texas 0.00% Reduce -23.4% 24,772 $101K
Viewpoint Capital Management LLC 0.04% No change 23,545 $96K
Hilton Capital Management, LLC 0.01% Reduce -67.1% 22,075 $90K
Hoey Investments, Inc. 0.01% No change 22,000 $90K
LaSalle St. Investment Advisors, LLC 0.01% Add +20.6% 20,500 $83K
Vanguard Personalized Indexing Management, LLC 0.00% Reduce -0.1% 20,179 $82K
T3 Companies, LLC 0.11% — 20,000 $81K
Stifel Financial Corp. 0.00% No change 19,314 $79K
Victory Capital Management Inc. 0.00% Add +14.8% 19,098 $78K
Polymer Capital Management (US) LLC 0.01% Add +32.5% 18,285 $74K
Pictet Asset Management Holding SA 0.00% New 18,081 $74K
Sei Investments Co. 0.00% No change 17,668 $72K
Cetera Investment Advisers 0.00% Add +42.8% 17,431 $71K
BNP Paribas Financial Markets 0.00% Reduce -74.3% 17,315 $70K
Quantinno Capital Management LP 0.00% New 16,711 $68K
Oxford Asset Management LLP 0.02% New 16,684 $68K
Syon Capital LLC 0.00% No change 16,663 $68K
Captrust Financial Advisors 0.00% Add +8.1% 16,444 $67K
Activest Wealth Management 0.01% New 16,300 $66K
Callan Family Office, LLC 0.00% New 16,032 $65K
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors 0.01% Add +43.2% 15,750 $64K
Freestone Capital Holdings, LLC 0.00% New 15,300 $62K
Citadel Advisors 0.00% Reduce -99.8% 13,541 $55K
Ameritas Investment Partners, Inc. 0.00% Add +3.5% 13,411 $55K
Focus Partners Advisor Solutions, LLC 0.00% New 13,407 $55K
Xponance LLC 0.00% Add +25.6% 13,068 $53K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +29.4% 12,944 $53K
PNC Financial Services Group, Inc. 0.00% No change 12,043 $49K
Mariner, LLC 0.00% Reduce -8.2% 11,786 $48K
Griffin Asset Management, Inc. 0.01% No change 11,620 $47K
Russell Investments Group, Ltd. 0.00% No change 11,051 $45K
Commonwealth Equity Services, LLC 0.00% New 10,975 $45K
Cibc World Markets Corp. 0.00% — 10,930 $44K
Neuberger Berman Group LLC 0.00% Reduce -3.9% 10,746 $44K
Foguth Wealth Management, LLC. 0.01% — 10,402 $44K
Lyell Wealth Management, LP 0.00% No change 10,500 $43K
Mercer Global Advisors Inc. 0.00% Add +1.4% 10,222 $42K
Nisa Investment Advisors, LLC 0.00% Reduce -7.4% 10,101 $41K
LRI Investments, LLC 0.00% New 10,000 $41K
Jacobi Capital Management LLC 0.00% New 10,000 $41K
TD Waterhouse Canada Inc. 0.00% No change 10,000 $41K
Rockefeller Capital Management L.P. 0.00% Add +74.3% 9,588 $39K
Jones Financial Companies LLLP 0.00% Add +22.0% 9,178 $37K
Sterling Capital Management LLC 0.00% Add +4.2% 8,549 $35K
Redwood Park Advisors LLC 0.02% No change 7,140 $29K
Royal Bank of Canada 0.00% Reduce -98.8% 6,947 $28K
Simplex Trading, LLC 0.00% Reduce -91.7% 5,996 $24K
IFP Advisors, Inc 0.00% No change 5,799 $24K
GF Fund Management Co. LTD. 0.00% Reduce -6.0% 5,234 $21K
Amalgamated Bank 0.00% Add +13.7% 5,190 $21K
Kestra Advisory Services, LLC 0.00% New 5,150 $21K
Atlantic Union Bankshares Corp 0.00% New 5,012 $20K
Washington Trust Advisors, Inc. 0.00% New 5,000 $20K
EFG International AG 0.00% — 5,000 $20K
Blue Trust, Inc. 0.00% Reduce -27.5% 4,716 $19K
Clearstead Advisors, LLC 0.00% Reduce -32.6% 4,651 $19K
Signaturefd, LLC 0.00% No change 3,507 $14K
EverSource Wealth Advisors, LLC 0.00% No change 3,402 $14K
Essential Partners LLC 0.00% Add +0.3% 3,313 $13K
Farther Finance Advisors, LLC 0.00% Add +24.6% 2,491 $10K
True Wealth Design, LLC 0.00% No change 2,490 $10K
International Assets Investment Management, LLC 0.00% New 2,250 $9K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +43.8% 2,281 $9K
Lanark Financial, Inc. 0.00% New 2,100 $9K
Hurley Capital, LLC 0.00% No change 2,000 $8K
Los Angeles Capital Management LLC 0.00% Reduce -93.6% 1,494 $7K
SBI Securities Co., Ltd. 0.00% Reduce -66.2% 1,638 $7K
Tower Research Capital LLC (TRC) 0.00% Reduce -80.6% 1,584 $6K
Arlington Trust Co LLC 0.00% No change 1,520 $6K
Quadrant Capital Group LLC 0.00% No change 1,480 $6K
Quantbot Technologies LP 0.00% New 1,287 $5K
Allworth Financial LP 0.00% Add +15.4% 1,167 $5K
Triumph Capital Management 0.00% New 1,000 $4K
Global Retirement Partners, LLC 0.00% New 1,000 $4K
Federation des caisses Desjardins du Quebec 0.00% New 1,000 $4K
Physician Wealth Advisors, Inc. 0.00% No change 975 $4K
Daiwa Securities Group Inc. 0.00% No change 767 $3K
US Bancorp \de 0.00% No change 585 $2K
Smartleaf Asset Management LLC 0.00% No change 532 $2K
Optiver Holding B.V. 0.00% Reduce -72.3% 509 $2K
Mark Sheptoff Financial Planning, LLC 0.00% New 500 $2K
MAI Capital Management 0.00% No change 474 $2K
Rachor Investment Advisory Services, LLC 0.00% — 369 $2K
Rothschild Investment LLC 0.00% Add +4.5% 324 $1K
GAMMA Investing LLC 0.00% New 255 $1K
Torren Management, LLC 0.00% — 191 $777
Parkside Financial Bank & Trust 0.00% No change 186 $758
Creative Financial Designs Inc. 0.00% New 100 $407
Bartlett & Co. Wealth Management LLC 0.00% No change 100 $407
Sunbelt Securities, Inc. 0.00% No change 22 $90
CIBC Private Wealth Group LLC 0.00% No change 4 $16
Covestor Ltd 0.00% Reduce -3.9% 25 $0

"% of holder's portfolio" is SANA's weight in each manager's 13F, not the share of Sana Biotechnology Inc. the manager owns.