Tango TherapeuticsTNGX
13F holders, Q3 2025 (September 30)141holders +26
37new positions
9sold out
7famous investors
$8.40avg. 13F price*
At the end of Q3 2025, 141 institutions reported holding Tango Therapeutics Inc. (TNGX) in their 13F filings, up 26 from Q2 2025. 37 opened new positions and 9 sold out. The largest holders were TRV GP Iv, LLC ($116.5M), Farallon Capital Management, L.L.C. ($90.4M) and EcoR1 Capital, LLC ($89.3M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio).
- Company
- Tango Therapeutics Inc.
- CUSIP
- 87583X109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $116.7M |
| Exits | 9 | $3.7M |
All 13F filers, Q2 2025 → Q3 2025: 26,540,338 shares bought and 13,767,367 shares sold, net +12,772,971 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 141 holders
| TRV GP Iv, LLC | 42.51% | Reduce -17.8% | 13,863,975 | $116.5M |
| Farallon Capital Management, L.L.C. | 0.51% | Add +17.5% | 10,757,000 | $90.4M |
| EcoR1 Capital, LLC | 4.29% | No change | 10,630,736 | $89.3M |
| Boxer Capital Management, LLC | 26.17% | No change | 9,771,485 | $82.1M |
| TCG Crossover Management, LLC | 3.53% | Reduce -20.5% | 8,536,196 | $71.7M |
| Woodline Partners LP | 0.24% | Add +0.0% | 6,029,928 | $50.7M |
| Siren, L.L.C. | 1.93% | Add +74.8% | 5,883,188 | $49.4M |
| BlackRock, Inc. | 0.00% | Add +3.4% | 5,646,919 | $47.4M |
| Nextech Invest Ltd. | 7.08% | No change | 5,533,980 | $46.5M |
| Vanguard Group Inc. | 0.00% | Add +25.5% | 5,052,003 | $42.4M |
| Gilead Sciences, Inc. | 2.28% | No change | 4,854,443 | $40.8M |
| T. Rowe Price Investment Management, Inc. | 0.02% | Add +11.3% | 3,526,359 | $29.6M |
| Balyasny Asset Management L.P. | 0.06% | Add +6.9% | 3,472,207 | $29.2M |
| State Street Corp. | 0.00% | Add +143.4% | 3,365,205 | $28.3M |
| Paradigm Biocapital Advisors LP | 0.77% | New | 3,086,184 | $25.9M |
| Point72 Asset Management | 0.06% | New | 2,919,450 | $24.5M |
| Bain Capital Life Sciences Investors, LLC | 1.51% | No change | 2,712,008 | $22.8M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | Reduce -57.5% | 2,511,000 | $21.1M |
| Janus Henderson Group PLC | 0.01% | New | 2,302,274 | $19.3M |
| Ra Capital Management, L.P. | 0.21% | No change | 2,000,000 | $16.8M |
| Geode Capital Management, LLC | 0.00% | Add +6.4% | 1,882,777 | $15.8M |
| Nantahala Capital Management, LLC | 0.94% | Reduce -47.4% | 1,809,948 | $15.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +1295.3% | 1,509,475 | $12.7M |
| Commodore Capital LP | 0.62% | No change | 1,500,000 | $12.6M |
| Marshall Wace, LLP | 0.01% | Reduce -14.5% | 1,489,518 | $12.5M |
| Deep Track Capital, LP | 0.34% | New | 1,454,562 | $12.2M |
| Millennium Management | 0.01% | Reduce -26.9% | 1,295,401 | $10.9M |
| Invesco Ltd. | 0.00% | Add +982.9% | 1,031,917 | $8.7M |
| Logos Global Management LP | 0.79% | New | 950,000 | $8.0M |
| Nuveen, LLC | 0.00% | Add +109.5% | 928,012 | $7.8M |
| Franklin Resources Inc. | 0.00% | Add +640.3% | 926,904 | $7.8M |
| Vivo Capital, LLC | 0.53% | Add +29.4% | 776,699 | $6.5M |
| Candriam S.C.A. | 0.03% | No change | 708,812 | $6.0M |
| Bessemer Group Inc. | 0.01% | Add +0.0% | 708,398 | $6.0M |
| ArrowMark Colorado Holdings LLC | 0.11% | No change | 708,385 | $6.0M |
| Dimensional Fund Advisors LP | 0.00% | Add +28.1% | 672,735 | $5.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +9.4% | 658,292 | $5.5M |
| Northern Trust Corp. | 0.00% | Add +0.8% | 605,561 | $5.1M |
| Avoro Capital Advisors LLC | 0.06% | New | 545,000 | $4.6M |
| D. E. Shaw & Co. | 0.00% | New | 430,379 | $3.6M |
| Great Lakes Advisors, LLC | 0.03% | New | 423,851 | $3.6M |
| Voloridge Investment Management, LLC | 0.01% | New | 384,207 | $3.2M |
| Barclays PLC | 0.00% | Add +163.7% | 365,680 | $3.1M |
| Soleus Capital Management, L.P. | 0.13% | Reduce -58.9% | 300,000 | $2.5M |
| Royal Bank of Canada | 0.00% | Add +14.0% | 287,499 | $2.4M |
| Wellington Management Group LLP | 0.00% | New | 253,288 | $2.1M |
| Morgan Stanley | 0.00% | Reduce -52.9% | 251,793 | $2.1M |
| Stempoint Capital LP | 0.42% | Add +17.5% | 245,378 | $2.1M |
| Readystate Asset Management LP | 0.20% | Reduce -41.4% | 245,109 | $2.1M |
| Cubist Systematic Strategies, LLC | 0.03% | New | 240,655 | $2.0M |
| Fred Alger Management, LLC | 0.01% | Add +20.4% | 230,316 | $1.9M |
| Congress Asset Management Co. | 0.01% | Add +0.4% | 228,120 | $1.9M |
| Fisher Asset Management | 0.00% | Reduce -6.1% | 210,352 | $1.8M |
| Trexquant Investment LP | 0.02% | New | 199,081 | $1.7M |
| TRV GP Vi, LLC | 1.49% | No change | 194,174 | $1.6M |
| Bank of New York Mellon Corp | 0.00% | Add +2.3% | 192,348 | $1.6M |
| UBS Group AG | 0.00% | Reduce -42.1% | 160,478 | $1.3M |
| Susquehanna Fundamental Investments, LLC | 0.05% | Reduce -1.6% | 157,233 | $1.3M |
| Bank of America Corp. | 0.00% | Add +229.7% | 155,447 | $1.3M |
| Rafferty Asset Management, LLC | 0.00% | New | 145,316 | $1.2M |
| Two Sigma Investments, LP | 0.00% | Add +550.1% | 144,432 | $1.2M |
| Blue Owl Capital Holdings LP | 0.31% | Reduce -85.3% | 119,416 | $1.0M |
| Rhumbline Advisers | 0.00% | Reduce -4.0% | 107,839 | $906K |
| Alliancebernstein L.P. | 0.00% | Reduce -3.5% | 102,270 | $859K |
| Two Sigma Advisers, LP | 0.00% | New | 94,100 | $790K |
| Susquehanna International Group, LLP | 0.00% | Reduce -63.4% | 88,839 | $746K |
| ExodusPoint Capital Management, LP | 0.01% | New | 81,238 | $682K |
| AQR Capital Management | 0.00% | Add +0.3% | 79,175 | $665K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $497K |
| Deutsche Bank AG | 0.00% | Add +12.3% | 59,149 | $497K |
| Renaissance Technologies | 0.00% | Reduce -15.6% | 55,300 | $465K |
| Wells Fargo & Company | 0.00% | Add +11.8% | 55,005 | $462K |
| Tudor Investment Corporation | 0.00% | New | 53,572 | $450K |
| MetLife Investment Management, LLC | 0.00% | No change | 47,726 | $401K |
| T. Rowe Price Associates Inc. | 0.00% | Add +5.9% | 40,669 | $343K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -3.8% | 40,398 | $340K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 36,963 | $310K |
| Quadrature Capital Ltd | 0.00% | New | 36,189 | $303K |
| Janney Montgomery Scott LLC | 0.00% | Reduce -8.9% | 36,000 | $302K |
| Creative Planning | 0.00% | New | 35,244 | $296K |
| JPMorgan Chase & Co. | 0.00% | Reduce -49.1% | 33,916 | $285K |
| Harvest Investment Services, LLC | 0.05% | New | 31,840 | $267K |
| Profund Advisors LLC | 0.01% | New | 31,288 | $263K |
| Clear Harbor Asset Management, LLC | 0.02% | Add +0.0% | 30,300 | $255K |
| J. Goldman & Co LP | 0.01% | New | 29,036 | $244K |
| Intech Investment Management LLC | 0.00% | Reduce -38.4% | 28,152 | $236K |
| Simplicity Wealth,LLC | 0.01% | No change | 26,961 | $226K |
| EverSource Wealth Advisors, LLC | 0.01% | Add +0.1% | 26,653 | $224K |
| Verition Fund Management LLC | 0.00% | New | 24,752 | $208K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -21.2% | 22,694 | $191K |
| Virtus Investment Advisers, LLC | 0.05% | Add +21.0% | 22,532 | $189K |
| Bridgeway Capital Management, LLC | 0.00% | Reduce -82.8% | 21,500 | $181K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +16.4% | 20,548 | $173K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -0.8% | 20,213 | $170K |
| China Universal Asset Management Co., Ltd. | 0.01% | Reduce -10.4% | 19,502 | $164K |
| Citigroup Inc. | 0.00% | Reduce -40.2% | 18,102 | $152K |
| TD Asset Management Inc | 0.00% | New | 18,072 | $152K |
| Los Angeles Capital Management LLC | 0.00% | Add +67.0% | 17,185 | $144K |
| ProShare Advisors LLC | 0.00% | Reduce -17.9% | 16,230 | $136K |
| New York State Common Retirement Fund | 0.00% | Add +136.9% | 15,576 | $131K |
"% of holder's portfolio" is TNGX's weight in each manager's 13F, not the share of Tango Therapeutics Inc. the manager owns.