Tango TherapeuticsTNGX
13F holders, Q4 2025 (December 31)170holders +29
49new positions
22sold out
7famous investors
$8.86avg. 13F price*
At the end of Q4 2025, 170 institutions reported holding Tango Therapeutics Inc. (TNGX) in their 13F filings, up 29 from Q3 2025. 49 opened new positions and 22 sold out. The largest holders were Farallon Capital Management, L.L.C. ($115.7M), TCG Crossover Management, LLC ($113.1M) and Boxer Capital Management, LLC ($96.4M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Tango Therapeutics Inc.
- CUSIP
- 87583X109
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 49 | $179.2M |
| Exits | 22 | $201.3M |
All 13F filers, Q3 2025 → Q4 2025: 72,676,026 shares bought and 40,645,685 shares sold, net +32,030,341 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 170 holders
| Farallon Capital Management, L.L.C. | 0.60% | Add +21.4% | 13,061,411 | $115.7M |
| TCG Crossover Management, LLC | 3.74% | Add +49.5% | 12,762,094 | $113.1M |
| Boxer Capital Management, LLC | 21.10% | Add +11.3% | 10,876,219 | $96.4M |
| Adage Capital Partners Gp, L.L.C. | 0.14% | Add +322.5% | 10,607,924 | $94.0M |
| Woodline Partners LP | 0.35% | Add +67.0% | 10,072,225 | $89.2M |
| BlackRock, Inc. | 0.00% | Add +51.3% | 8,540,797 | $75.7M |
| Siren, L.L.C. | 2.16% | Add +38.8% | 8,165,374 | $72.3M |
| TRV GP Iv, LLC | 27.35% | Reduce -43.2% | 7,874,574 | $69.8M |
| Nextech Invest Ltd. | 6.22% | Add +31.3% | 7,266,081 | $64.4M |
| Vanguard Group Inc. | 0.00% | Add +33.6% | 6,750,977 | $59.8M |
| State Street Corp. | 0.00% | Add +84.8% | 6,218,567 | $55.1M |
| Balyasny Asset Management L.P. | 0.09% | Add +52.0% | 5,278,580 | $46.8M |
| Goldman Sachs Group Inc. | 0.01% | Add +227.4% | 4,942,414 | $43.8M |
| Logos Global Management LP | 2.48% | Add +342.1% | 4,200,000 | $37.2M |
| Bellevue Group AG | 0.66% | New | 3,927,670 | $34.8M |
| Caligan Partners LP | 3.02% | New | 3,729,895 | $33.0M |
| Nantahala Capital Management, LLC | 1.89% | Add +97.4% | 3,572,633 | $31.7M |
| Deerfield Management Company, L.P. | 0.38% | New | 2,906,946 | $25.8M |
| FMR LLC | 0.00% | Add +44524.2% | 2,867,548 | $25.4M |
| Montanova Capital, LLC | 0.59% | New | 2,662,227 | $23.6M |
| Janus Henderson Group PLC | 0.01% | Add +14.8% | 2,644,237 | $23.5M |
| Geode Capital Management, LLC | 0.00% | Add +35.6% | 2,553,656 | $22.6M |
| Deep Track Capital, LP | 0.50% | Add +68.8% | 2,454,562 | $21.7M |
| Vivo Capital, LLC | 1.23% | Add +177.4% | 2,154,780 | $19.1M |
| Point72 Asset Management | 0.03% | Reduce -32.4% | 1,974,035 | $17.5M |
| RTW Investments, LP | 0.13% | New | 1,491,228 | $13.2M |
| Morgan Stanley | 0.00% | Add +464.7% | 1,421,794 | $12.6M |
| Franklin Resources Inc. | 0.00% | Add +50.8% | 1,398,057 | $12.4M |
| D. E. Shaw & Co. | 0.01% | Add +138.3% | 1,025,553 | $9.1M |
| Affinity Asset Advisors, LLC | 0.66% | New | 1,000,000 | $8.9M |
| UBS Group AG | 0.00% | Add +517.2% | 990,458 | $8.8M |
| Boothbay Fund Management, LLC | 0.23% | New | 957,282 | $8.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +27.8% | 840,992 | $7.5M |
| Northern Trust Corp. | 0.00% | Add +32.6% | 803,199 | $7.1M |
| Candriam S.C.A. | 0.03% | No change | 708,812 | $6.3M |
| ArrowMark Colorado Holdings LLC | 0.14% | No change | 708,385 | $6.3M |
| Bessemer Group Inc. | 0.01% | No change | 708,398 | $6.3M |
| Bain Capital Life Sciences Investors, LLC | 0.44% | Reduce -75.9% | 653,493 | $5.8M |
| Millennium Management | 0.00% | Reduce -54.2% | 593,004 | $5.3M |
| Sphera Funds Management LTD. | 1.01% | New | 544,563 | $4.8M |
| Perceptive Advisors LLC | 0.08% | New | 513,035 | $4.5M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -27.6% | 487,076 | $4.3M |
| Bank of America Corp. | 0.00% | Add +207.5% | 478,062 | $4.2M |
| T. Rowe Price Investment Management, Inc. | 0.00% | Reduce -87.3% | 446,213 | $4.0M |
| Rock Springs Capital Management LP | 0.18% | New | 386,915 | $3.4M |
| Barclays PLC | 0.00% | Add +0.7% | 368,187 | $3.3M |
| Mass General Brigham, Inc | 0.39% | — | 354,192 | $3.1M |
| Bank of New York Mellon Corp | 0.00% | Add +78.8% | 343,840 | $3.0M |
| Marshall Wace, LLP | 0.00% | Reduce -77.9% | 329,231 | $2.9M |
| Qube Research & Technologies Ltd | 0.00% | New | 318,676 | $2.8M |
| Nuveen, LLC | 0.00% | Reduce -67.6% | 300,441 | $2.7M |
| Great Lakes Advisors, LLC | 0.02% | Reduce -30.6% | 294,303 | $2.6M |
| Acuta Capital Partners, LLC | 1.70% | New | 282,732 | $2.5M |
| Voloridge Investment Management, LLC | 0.01% | Reduce -33.6% | 255,127 | $2.3M |
| Congress Asset Management Co. | 0.01% | Add +2.9% | 234,628 | $2.1M |
| Wellington Management Group LLP | 0.00% | Reduce -7.7% | 233,857 | $2.1M |
| Rafferty Asset Management, LLC | 0.01% | Add +55.9% | 226,601 | $2.0M |
| Seven Fleet Capital Management LP | 1.29% | — | 215,172 | $1.9M |
| Integral Health Asset Management, LLC | 0.09% | New | 200,000 | $1.8M |
| TRV GP Vi, LLC | 1.16% | No change | 194,174 | $1.7M |
| Fisher Asset Management | 0.00% | Reduce -10.8% | 187,693 | $1.7M |
| Invesco Ltd. | 0.00% | Reduce -82.8% | 177,610 | $1.6M |
| Squarepoint Ops LLC | 0.00% | New | 173,936 | $1.5M |
| Citadel Advisors | 0.00% | New | 151,880 | $1.3M |
| Two Sigma Investments, LP | 0.00% | No change | 144,432 | $1.3M |
| ADAR1 Capital Management, LLC | 0.09% | New | 140,021 | $1.2M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.00% | New | 129,476 | $1.1M |
| Rhumbline Advisers | 0.00% | Add +19.7% | 129,107 | $1.1M |
| Verition Fund Management LLC | 0.01% | Add +392.0% | 121,781 | $1.1M |
| Wells Fargo & Company | 0.00% | Add +120.3% | 121,186 | $1.1M |
| Gsa Capital Partners LLP | 0.09% | New | 118,593 | $1.1M |
| Alliancebernstein L.P. | 0.00% | Add +4.1% | 106,490 | $944K |
| Trexquant Investment LP | 0.01% | Reduce -47.1% | 105,268 | $933K |
| Swiss National Bank | 0.00% | New | 87,800 | $778K |
| Profund Advisors LLC | 0.02% | Add +167.7% | 83,759 | $742K |
| AQR Capital Management | 0.00% | Add +3.9% | 82,233 | $729K |
| Deutsche Bank AG | 0.00% | Add +25.4% | 74,203 | $657K |
| Tudor Investment Corporation | 0.00% | Add +27.4% | 68,251 | $605K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +55.0% | 62,634 | $552K |
| MetLife Investment Management, LLC | 0.00% | Add +25.1% | 59,692 | $529K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | Add +60.5% | 59,330 | $526K |
| T. Rowe Price Associates Inc. | 0.00% | Add +43.7% | 58,434 | $518K |
| Los Angeles Capital Management LLC | 0.00% | Add +273.8% | 64,243 | $512K |
| JPMorgan Chase & Co. | 0.00% | Add +67.6% | 56,835 | $504K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 60,000 | $502K |
| Sei Investments Co. | 0.00% | Add +436.9% | 53,927 | $478K |
| Graham Capital Management, L.P. | 0.02% | New | 51,319 | $455K |
| Canada Pension Plan Investment Board | 0.00% | New | 50,400 | $447K |
| California State Teachers Retirement System | 0.00% | Add +906.9% | 48,210 | $427K |
| Voya Investment Management LLC | 0.00% | Add +255.1% | 47,811 | $424K |
| SmartHarvest Portfolios, LLC | 0.14% | — | 46,123 | $409K |
| Creative Planning | 0.00% | Add +18.9% | 41,907 | $371K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | New | 41,453 | $367K |
| Legal & General Group Plc | 0.00% | Add +511.8% | 39,430 | $349K |
| Intech Investment Management LLC | 0.00% | Add +38.3% | 38,941 | $345K |
| XTX Topco Ltd | 0.01% | New | 37,838 | $335K |
| Citigroup Inc. | 0.00% | Add +100.2% | 36,236 | $321K |
| Janney Montgomery Scott LLC | 0.00% | No change | 36,000 | $319K |
| Susquehanna International Group, LLP | 0.00% | Reduce -60.4% | 35,216 | $312K |
| Philadelphia Financial Management of San Francisco, LLC | 0.06% | New | 33,291 | $295K |
"% of holder's portfolio" is TNGX's weight in each manager's 13F, not the share of Tango Therapeutics Inc. the manager owns.