Xeris Biopharma HoldingsXERS
13F holders, Q1 2025 (March 31)199holders +37
55new positions
18sold out
8famous investors
$5.49avg. 13F price*
At the end of Q1 2025, 199 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 37 from Q4 2024. 55 opened new positions and 18 sold out. The largest holders were BlackRock, Inc. ($59.3M), Vanguard Group Inc. ($44.5M) and Morgan Stanley ($23.5M). 8 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Xeris Biopharma Holdings Inc.
- CUSIP
- 98422E103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 55 | $42.1M |
| Exits | 18 | $16.8M |
All 13F filers, Q4 2024 → Q1 2025: 29,250,499 shares bought and 7,567,426 shares sold, net +21,683,073 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 199 holders
| BlackRock, Inc. | 0.00% | Reduce -0.3% | 10,794,601 | $59.3M |
| Vanguard Group Inc. | 0.00% | Add +2.7% | 8,109,644 | $44.5M |
| Morgan Stanley | 0.00% | Add +49.0% | 4,288,281 | $23.5M |
| Geode Capital Management, LLC | 0.00% | Add +1.6% | 3,405,826 | $18.7M |
| State Street Corp. | 0.00% | Reduce -0.5% | 3,325,255 | $18.3M |
| D. E. Shaw & Co. | 0.02% | Add +123.9% | 3,052,372 | $16.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +75.4% | 2,790,014 | $15.3M |
| Rosalind Advisors, Inc. | 6.68% | Reduce -19.6% | 2,495,986 | $13.7M |
| Millennium Management | 0.01% | Add +19.0% | 2,317,972 | $12.7M |
| Nuveen, LLC | 0.00% | — | 2,229,507 | $12.2M |
| Renaissance Technologies | 0.02% | Add +3.0% | 2,162,640 | $11.9M |
| JPMorgan Chase & Co. | 0.00% | Add +102.7% | 2,114,709 | $11.6M |
| Qube Research & Technologies Ltd | 0.02% | Add +301.3% | 1,844,583 | $10.1M |
| Parkman Healthcare Partners LLC | 1.16% | Add +207.8% | 1,780,454 | $9.8M |
| Bank of America Corp. | 0.00% | Add +72.4% | 1,709,409 | $9.4M |
| Legal & General Group Plc | 0.00% | Add +512.5% | 1,411,614 | $7.7M |
| Driehaus Capital Management LLC | 0.07% | Add +137.6% | 1,411,540 | $7.7M |
| Voloridge Investment Management, LLC | 0.03% | New | 1,351,114 | $7.4M |
| Citadel Advisors | 0.01% | Add +61.7% | 1,347,859 | $7.4M |
| Northern Trust Corp. | 0.00% | Add +0.4% | 1,201,200 | $6.6M |
| Knott David M Jr | 2.88% | Add +11.0% | 1,110,000 | $6.1M |
| Prudential Financial Inc. | 0.01% | Add +2874.3% | 1,098,845 | $6.0M |
| Invesco Ltd. | 0.00% | Add +1387.8% | 1,026,838 | $5.6M |
| AQR Capital Management | 0.01% | Add +13.4% | 946,766 | $5.2M |
| Informed Momentum Co LLC | 0.89% | Add +320.3% | 934,646 | $5.1M |
| Two Sigma Advisers, LP | 0.01% | Add +6636.1% | 925,615 | $5.1M |
| Two Sigma Investments, LP | 0.01% | New | 890,337 | $4.9M |
| UBS Group AG | 0.00% | Reduce -50.2% | 863,776 | $4.7M |
| Norges Bank | 0.00% | New | 823,800 | $4.5M |
| Jane Street Group, LLC | 0.01% | Add +167.8% | 820,222 | $4.5M |
| Cubist Systematic Strategies, LLC | 0.06% | New | 811,607 | $4.5M |
| Deutsche Bank AG | 0.00% | Add +492.8% | 756,407 | $4.2M |
| Kennedy Capital Management LLC | 0.10% | Add +10.4% | 735,087 | $4.0M |
| Essex Investment Management Co. LLC | 0.84% | Add +53.8% | 730,444 | $4.0M |
| Walleye Capital LLC | 0.05% | New | 691,719 | $3.8M |
| Federated Hermes, Inc. | 0.01% | Add +36542.7% | 687,783 | $3.8M |
| Susquehanna International Group, LLP | 0.01% | Add +494.1% | 637,782 | $3.5M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +482.7% | 600,167 | $3.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +244.1% | 589,471 | $3.2M |
| CenterBook Partners LP | 0.17% | Reduce -31.6% | 472,075 | $2.6M |
| Redmile Group, LLC | 0.23% | No change | 451,099 | $2.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +5.2% | 423,775 | $2.3M |
| Jump Financial, LLC | 0.04% | Add +1371.4% | 423,523 | $2.3M |
| Wellington Management Group LLP | 0.00% | Reduce -15.7% | 392,099 | $2.2M |
| Bank of New York Mellon Corp | 0.00% | Add +11.8% | 360,324 | $2.0M |
| BNP Paribas Financial Markets | 0.00% | Add +244.8% | 344,888 | $1.9M |
| FMR LLC | 0.00% | Add +552.0% | 311,472 | $1.7M |
| Barclays PLC | 0.00% | Reduce -19.3% | 280,635 | $1.5M |
| Voss Capital, LP | 0.12% | New | 275,000 | $1.5M |
| IHT Wealth Management, LLC | 0.05% | Reduce -2.7% | 262,805 | $1.4M |
| Jacobs Levy Equity Management, Inc. | 0.01% | New | 255,560 | $1.4M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | New | 252,000 | $1.4M |
| PDT Partners, LLC | 0.09% | New | 239,600 | $1.3M |
| Tudor Investment Corporation | 0.01% | Reduce -26.2% | 225,186 | $1.2M |
| Legato Capital Management LLC | 0.16% | Add +52.9% | 217,318 | $1.2M |
| XTX Topco Ltd | 0.06% | New | 216,228 | $1.2M |
| Royal Bank of Canada | 0.00% | Add +1411.2% | 213,084 | $1.2M |
| Commonwealth Equity Services, LLC | 0.00% | Add +5.3% | 197,443 | $1.1M |
| Rhumbline Advisers | 0.00% | Add +6.3% | 192,281 | $1.1M |
| Brevan Howard Capital Management LP | 0.03% | New | 192,276 | $1.1M |
| Raymond James Financial Inc. | 0.00% | Add +1271.2% | 180,316 | $990K |
| T. Rowe Price Associates Inc. | 0.00% | Add +3.5% | 176,393 | $969K |
| Diversified Trust Co. | 0.02% | No change | 175,739 | $965K |
| Man Group plc | 0.00% | New | 175,247 | $962K |
| Thompson Siegel & Walmsley LLC | 0.02% | Add +13.1% | 172,784 | $949K |
| Ameriprise Financial Inc. | 0.00% | Reduce -19.9% | 168,102 | $923K |
| Semanteon Capital Management, LP | 0.47% | New | 156,191 | $857K |
| Ieq Capital, LLC | 0.01% | Add +129.2% | 155,184 | $852K |
| Panagora Asset Management Inc. | 0.00% | New | 145,526 | $799K |
| Alliancebernstein L.P. | 0.00% | Add +10.1% | 144,830 | $795K |
| Mackenzie Financial Corp. | 0.00% | Add +9.3% | 142,104 | $780K |
| Gsa Capital Partners LLP | 0.07% | Add +178.3% | 138,735 | $762K |
| Fred Alger Management, LLC | 0.00% | New | 134,016 | $736K |
| Graham Capital Management, L.P. | 0.03% | Add +89.2% | 133,668 | $734K |
| Russell Investments Group, Ltd. | 0.00% | Add +632.6% | 131,687 | $723K |
| Globeflex Capital L P | 0.06% | No change | 125,210 | $687K |
| Occudo Quantitative Strategies LP | 0.09% | Add +132.8% | 120,424 | $672K |
| Roundview Capital LLC | 0.05% | No change | 120,000 | $659K |
| Citigroup Inc. | 0.00% | Reduce -10.8% | 118,208 | $649K |
| Brown Advisory Inc. | 0.00% | Reduce -39.7% | 114,698 | $630K |
| Principal Financial Group Inc. | 0.00% | Add +0.5% | 113,746 | $624K |
| Franklin Resources Inc. | 0.00% | Add +451.8% | 107,936 | $593K |
| Creative Planning | 0.00% | Add +16.9% | 106,732 | $586K |
| Stonepine Capital Management, LLC | 0.55% | Reduce -43.9% | 102,265 | $561K |
| Alpine Global Management, LLC | 0.16% | Reduce -37.5% | 100,000 | $549K |
| Sei Investments Co. | 0.00% | New | 97,491 | $535K |
| Point72 Asset Management | 0.00% | New | 88,373 | $485K |
| Bantamac Capital, LLC | 0.22% | New | 85,111 | $467K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.5% | 83,982 | $461K |
| MetLife Investment Management, LLC | 0.00% | Reduce -6.5% | 81,769 | $449K |
| HRT Financial LP | 0.00% | Add +292.4% | 81,112 | $445K |
| Orbimed Advisors LLC | 0.01% | No change | 80,420 | $442K |
| EntryPoint Capital, LLC | 0.19% | Add +43.5% | 75,706 | $416K |
| Sigma Planning Corp | 0.01% | Reduce -3.9% | 73,950 | $406K |
| Quarry LP | 0.10% | New | 70,751 | $388K |
| SG Americas Securities, LLC | 0.00% | Reduce -25.5% | 70,499 | $387K |
| Wells Fargo & Company | 0.00% | Reduce -11.6% | 69,881 | $384K |
| Corebridge Financial, Inc. | 0.00% | Reduce -1.5% | 68,698 | $377K |
| Cwm, LLC | 0.00% | Add +79.3% | 66,972 | $368K |
| GPS Wealth Strategies Group, LLC | 0.05% | No change | 66,925 | $367K |
"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.