Xeris Biopharma HoldingsXERS
13F holders, Q2 2025 (June 30)At the end of Q2 2025, 200 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 1 from Q1 2025. 23 opened new positions and 24 sold out. The largest holders were BlackRock, Inc. ($53.9M), Vanguard Group Inc. ($45.8M) and D. E. Shaw & Co. ($17.9M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Xeris Biopharma Holdings Inc.
- CUSIP
- 98422E103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 23 | $3.2M |
| Exits | 24 | $14.5M |
All 13F filers, Q1 2025 → Q2 2025: 13,969,335 shares bought and 11,099,696 shares sold, net +2,869,639 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 200 holders
| BlackRock, Inc. | 0.00% | Add +6.9% | 11,536,321 | $53.9M |
| Vanguard Group Inc. | 0.00% | Add +21.1% | 9,816,937 | $45.8M |
| D. E. Shaw & Co. | 0.02% | Add +25.6% | 3,835,407 | $17.9M |
| State Street Corp. | 0.00% | Add +13.8% | 3,783,200 | $17.7M |
| Geode Capital Management, LLC | 0.00% | Add +7.2% | 3,650,688 | $17.1M |
| Morgan Stanley | 0.00% | Reduce -15.1% | 3,642,584 | $17.0M |
| Qube Research & Technologies Ltd | 0.02% | Add +67.5% | 3,089,771 | $14.4M |
| Millennium Management | 0.01% | Add +26.6% | 2,933,620 | $13.7M |
| Nuveen, LLC | 0.00% | Add +16.6% | 2,600,442 | $12.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -18.6% | 2,271,486 | $10.6M |
| Rosalind Advisors, Inc. | 4.87% | Reduce -13.6% | 2,155,594 | $10.1M |
| Parkman Healthcare Partners LLC | 1.14% | Add +18.4% | 2,107,483 | $9.8M |
| Driehaus Capital Management LLC | 0.08% | Add +46.7% | 2,071,075 | $9.7M |
| Renaissance Technologies | 0.01% | Reduce -5.0% | 2,055,340 | $9.6M |
| Legal & General Group Plc | 0.00% | Add +27.8% | 1,804,203 | $8.4M |
| Bank of America Corp. | 0.00% | Reduce -2.7% | 1,663,490 | $7.8M |
| CenterBook Partners LP | 0.41% | Add +237.7% | 1,594,229 | $7.4M |
| Prudential Financial Inc. | 0.01% | Add +41.7% | 1,556,629 | $7.3M |
| Northern Trust Corp. | 0.00% | Add +7.7% | 1,293,530 | $6.0M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.02% | Add +108.3% | 1,227,959 | $5.7M |
| Two Sigma Investments, LP | 0.01% | Add +36.4% | 1,214,699 | $5.7M |
| Knott David M Jr | 2.24% | Reduce -4.5% | 1,060,000 | $5.0M |
| Two Sigma Advisers, LP | 0.01% | Add +14.2% | 1,056,779 | $4.9M |
| AQR Capital Management | 0.00% | Add +10.8% | 1,048,993 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -51.2% | 1,032,262 | $4.8M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -26.4% | 994,381 | $4.6M |
| Cubist Systematic Strategies, LLC | 0.04% | Add +8.5% | 880,314 | $4.1M |
| Kennedy Capital Management LLC | 0.09% | Add +11.0% | 816,147 | $3.8M |
| Jump Financial, LLC | 0.04% | Add +78.6% | 756,403 | $3.5M |
| Deutsche Bank AG | 0.00% | Reduce -2.6% | 736,927 | $3.4M |
| Essex Investment Management Co. LLC | 0.62% | Reduce -0.6% | 725,774 | $3.4M |
| Federated Hermes, Inc. | 0.01% | Add +0.5% | 691,381 | $3.2M |
| Informed Momentum Co LLC | 0.42% | Reduce -37.2% | 586,865 | $2.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +33.9% | 567,538 | $2.7M |
| Norges Bank | 0.00% | Reduce -31.8% | 561,700 | $2.6M |
| Redmile Group, LLC | 0.22% | No change | 451,099 | $2.1M |
| Barclays PLC | 0.00% | Add +51.2% | 424,248 | $2.0M |
| Susquehanna International Group, LLP | 0.00% | Reduce -36.3% | 406,202 | $1.9M |
| Wellington Management Group LLP | 0.00% | Add +1.8% | 399,291 | $1.9M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -35.2% | 389,066 | $1.8M |
| Acadian Asset Management LLC | 0.00% | Add +2078.0% | 383,237 | $1.8M |
| Bank of New York Mellon Corp | 0.00% | Add +4.7% | 377,127 | $1.8M |
| Y-Intercept (Hong Kong) Ltd | 0.04% | Add +655.2% | 336,214 | $1.6M |
| FMR LLC | 0.00% | Add +4.8% | 326,420 | $1.5M |
| Voss Capital, LP | 0.10% | Add +16.3% | 319,800 | $1.5M |
| Squarepoint Ops LLC | 0.00% | Add +1679.1% | 284,567 | $1.3M |
| State of Wisconsin Investment Board | 0.00% | Add +1271.3% | 278,020 | $1.3M |
| Thompson Siegel & Walmsley LLC | 0.02% | Add +54.2% | 266,387 | $1.2M |
| IHT Wealth Management, LLC | 0.03% | Add +0.4% | 263,805 | $1.2M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | No change | 252,000 | $1.2M |
| Walleye Capital LLC | 0.01% | Reduce -64.8% | 243,275 | $1.1M |
| UBS Group AG | 0.00% | Reduce -73.6% | 227,865 | $1.1M |
| Tudor Investment Corporation | 0.01% | No change | 225,186 | $1.1M |
| Legato Capital Management LLC | 0.12% | Reduce -0.2% | 216,805 | $1.0M |
| Rhumbline Advisers | 0.00% | Add +12.2% | 215,691 | $1.0M |
| Raymond James Financial Inc. | 0.00% | Add +16.0% | 209,146 | $977K |
| Stonepine Capital Management, LLC | 0.94% | Add +100.6% | 205,100 | $958K |
| Brevan Howard Capital Management LP | 0.01% | Add +6.6% | 205,024 | $957K |
| Commonwealth Equity Services, LLC | 0.00% | Add +0.1% | 197,743 | $923K |
| Jacobs Levy Equity Management, Inc. | 0.00% | Reduce -28.8% | 181,877 | $849K |
| Occudo Quantitative Strategies LP | 0.09% | Add +48.9% | 179,354 | $838K |
| Diversified Trust Co. | 0.02% | Reduce -3.1% | 170,235 | $795K |
| Quarry LP | 0.18% | Add +129.7% | 162,500 | $759K |
| Principal Financial Group Inc. | 0.00% | Add +35.3% | 153,937 | $719K |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -13.1% | 153,271 | $716K |
| Alpine Global Management, LLC | 0.18% | Add +50.0% | 150,000 | $701K |
| Ameriprise Financial Inc. | 0.00% | Reduce -11.3% | 149,028 | $696K |
| Alliancebernstein L.P. | 0.00% | No change | 144,830 | $676K |
| Mackenzie Financial Corp. | 0.00% | Reduce -2.8% | 138,092 | $645K |
| Bantamac Capital, LLC | 0.22% | Add +56.3% | 132,994 | $621K |
| Polen Capital Management LLC | 0.00% | New | 132,994 | $621K |
| Campbell & CO Investment Adviser LLC | 0.04% | New | 132,382 | $618K |
| Man Group plc | 0.00% | Reduce -25.3% | 130,849 | $611K |
| Graham Capital Management, L.P. | 0.02% | Reduce -6.2% | 125,417 | $586K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -6.5% | 123,189 | $575K |
| Roundview Capital LLC | 0.04% | No change | 120,000 | $560K |
| Creative Planning | 0.00% | Add +10.3% | 117,755 | $550K |
| Sei Investments Co. | 0.00% | Add +19.5% | 116,534 | $544K |
| Brown Advisory Inc. | 0.00% | No change | 114,698 | $536K |
| Harvest Investment Services, LLC | 0.12% | Add +141.0% | 111,970 | $523K |
| Ieq Capital, LLC | 0.00% | Reduce -30.1% | 108,495 | $507K |
| Franklin Resources Inc. | 0.00% | Reduce -4.3% | 103,278 | $482K |
| Intech Investment Management LLC | 0.00% | Add +88.5% | 94,437 | $441K |
| Invesco Ltd. | 0.00% | Reduce -91.6% | 86,194 | $403K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -2.2% | 82,138 | $384K |
| Globeflex Capital L P | 0.03% | Reduce -35.8% | 80,431 | $376K |
| Orbimed Advisors LLC | 0.01% | No change | 80,420 | $376K |
| Wells Fargo & Company | 0.00% | Add +15.0% | 80,366 | $375K |
| Citigroup Inc. | 0.00% | Reduce -34.4% | 77,534 | $362K |
| Simplex Trading, LLC | 0.01% | New | 76,644 | $357K |
| EntryPoint Capital, LLC | 0.17% | Reduce -3.7% | 72,899 | $340K |
| STRS Ohio | 0.00% | Add +7.5% | 65,500 | $306K |
| GPS Wealth Strategies Group, LLC | 0.03% | Reduce -3.0% | 64,925 | $303K |
| Gsa Capital Partners LLP | 0.02% | Reduce -55.1% | 62,322 | $291K |
| Cwm, LLC | 0.00% | Reduce -17.7% | 55,111 | $257K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +7.0% | 54,472 | $254K |
| Chevy Chase Trust Holdings, LLC | 0.00% | No change | 51,243 | $239K |
| Weiss Asset Management LP | 0.00% | No change | 50,001 | $234K |
| Quadrature Capital Ltd | 0.00% | Add +50.2% | 46,756 | $219K |
| Cetera Investment Advisers | 0.00% | Add +3.9% | 46,332 | $216K |
"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.