Xeris Biopharma HoldingsXERS

13F holders, Q1 2025 (March 31)
199holders +37
55new positions
18sold out
8famous investors
$5.49avg. 13F price*

At the end of Q1 2025, 199 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 37 from Q4 2024. 55 opened new positions and 18 sold out. The largest holders were BlackRock, Inc. ($59.3M), Vanguard Group Inc. ($44.5M) and Morgan Stanley ($23.5M). 8 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Xeris Biopharma Holdings Inc.
CUSIP
98422E103
Latest filing quarter
Q2 2026

History

Number of 13F holders

050100150200250 Q1 2024: 142Q1 2024Q2 2024: 135Q2 2024Q3 2024: 144Q3 2024Q4 2024: 162Q4 2024Q1 2025: 199Q1 2025Q2 2025: 200Q2 2025Q3 2025: 230Q3 2025Q4 2025: 224Q4 2025Q1 2026: 237Q1 2026Q2 2026: 240Q2 2026

Total Exit/New Position Q4 2024 → Q1 2025

InstitutionsTotal Value
New Positions55$42.1M
Exits18$16.8M

All 13F filers, Q4 2024 → Q1 2025: 29,250,499 shares bought and 7,567,426 shares sold, net +21,683,073 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 199 holders

BlackRock, Inc. 0.00% Reduce -0.3% 10,794,601 $59.3M
Vanguard Group Inc. 0.00% Add +2.7% 8,109,644 $44.5M
Morgan Stanley 0.00% Add +49.0% 4,288,281 $23.5M
Geode Capital Management, LLC 0.00% Add +1.6% 3,405,826 $18.7M
State Street Corp. 0.00% Reduce -0.5% 3,325,255 $18.3M
D. E. Shaw & Co. 0.02% Add +123.9% 3,052,372 $16.8M
Goldman Sachs Group Inc. 0.00% Add +75.4% 2,790,014 $15.3M
Rosalind Advisors, Inc. 6.68% Reduce -19.6% 2,495,986 $13.7M
Millennium Management 0.01% Add +19.0% 2,317,972 $12.7M
Nuveen, LLC 0.00% — 2,229,507 $12.2M
Renaissance Technologies 0.02% Add +3.0% 2,162,640 $11.9M
JPMorgan Chase & Co. 0.00% Add +102.7% 2,114,709 $11.6M
Qube Research & Technologies Ltd 0.02% Add +301.3% 1,844,583 $10.1M
Parkman Healthcare Partners LLC 1.16% Add +207.8% 1,780,454 $9.8M
Bank of America Corp. 0.00% Add +72.4% 1,709,409 $9.4M
Legal & General Group Plc 0.00% Add +512.5% 1,411,614 $7.7M
Driehaus Capital Management LLC 0.07% Add +137.6% 1,411,540 $7.7M
Voloridge Investment Management, LLC 0.03% New 1,351,114 $7.4M
Citadel Advisors 0.01% Add +61.7% 1,347,859 $7.4M
Northern Trust Corp. 0.00% Add +0.4% 1,201,200 $6.6M
Knott David M Jr 2.88% Add +11.0% 1,110,000 $6.1M
Prudential Financial Inc. 0.01% Add +2874.3% 1,098,845 $6.0M
Invesco Ltd. 0.00% Add +1387.8% 1,026,838 $5.6M
AQR Capital Management 0.01% Add +13.4% 946,766 $5.2M
Informed Momentum Co LLC 0.89% Add +320.3% 934,646 $5.1M
Two Sigma Advisers, LP 0.01% Add +6636.1% 925,615 $5.1M
Two Sigma Investments, LP 0.01% New 890,337 $4.9M
UBS Group AG 0.00% Reduce -50.2% 863,776 $4.7M
Norges Bank 0.00% New 823,800 $4.5M
Jane Street Group, LLC 0.01% Add +167.8% 820,222 $4.5M
Cubist Systematic Strategies, LLC 0.06% New 811,607 $4.5M
Deutsche Bank AG 0.00% Add +492.8% 756,407 $4.2M
Kennedy Capital Management LLC 0.10% Add +10.4% 735,087 $4.0M
Essex Investment Management Co. LLC 0.84% Add +53.8% 730,444 $4.0M
Walleye Capital LLC 0.05% New 691,719 $3.8M
Federated Hermes, Inc. 0.01% Add +36542.7% 687,783 $3.8M
Susquehanna International Group, LLP 0.01% Add +494.1% 637,782 $3.5M
Schonfeld Strategic Advisors LLC 0.02% Add +482.7% 600,167 $3.3M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +244.1% 589,471 $3.2M
CenterBook Partners LP 0.17% Reduce -31.6% 472,075 $2.6M
Redmile Group, LLC 0.23% No change 451,099 $2.5M
Charles Schwab Investment Management Inc. 0.00% Add +5.2% 423,775 $2.3M
Jump Financial, LLC 0.04% Add +1371.4% 423,523 $2.3M
Wellington Management Group LLP 0.00% Reduce -15.7% 392,099 $2.2M
Bank of New York Mellon Corp 0.00% Add +11.8% 360,324 $2.0M
BNP Paribas Financial Markets 0.00% Add +244.8% 344,888 $1.9M
FMR LLC 0.00% Add +552.0% 311,472 $1.7M
Barclays PLC 0.00% Reduce -19.3% 280,635 $1.5M
Voss Capital, LP 0.12% New 275,000 $1.5M
IHT Wealth Management, LLC 0.05% Reduce -2.7% 262,805 $1.4M
Jacobs Levy Equity Management, Inc. 0.01% New 255,560 $1.4M
Healthcare of Ontario Pension Plan Trust Fund 0.00% New 252,000 $1.4M
PDT Partners, LLC 0.09% New 239,600 $1.3M
Tudor Investment Corporation 0.01% Reduce -26.2% 225,186 $1.2M
Legato Capital Management LLC 0.16% Add +52.9% 217,318 $1.2M
XTX Topco Ltd 0.06% New 216,228 $1.2M
Royal Bank of Canada 0.00% Add +1411.2% 213,084 $1.2M
Commonwealth Equity Services, LLC 0.00% Add +5.3% 197,443 $1.1M
Rhumbline Advisers 0.00% Add +6.3% 192,281 $1.1M
Brevan Howard Capital Management LP 0.03% New 192,276 $1.1M
Raymond James Financial Inc. 0.00% Add +1271.2% 180,316 $990K
T. Rowe Price Associates Inc. 0.00% Add +3.5% 176,393 $969K
Diversified Trust Co. 0.02% No change 175,739 $965K
Man Group plc 0.00% New 175,247 $962K
Thompson Siegel & Walmsley LLC 0.02% Add +13.1% 172,784 $949K
Ameriprise Financial Inc. 0.00% Reduce -19.9% 168,102 $923K
Semanteon Capital Management, LP 0.47% New 156,191 $857K
Ieq Capital, LLC 0.01% Add +129.2% 155,184 $852K
Panagora Asset Management Inc. 0.00% New 145,526 $799K
Alliancebernstein L.P. 0.00% Add +10.1% 144,830 $795K
Mackenzie Financial Corp. 0.00% Add +9.3% 142,104 $780K
Gsa Capital Partners LLP 0.07% Add +178.3% 138,735 $762K
Fred Alger Management, LLC 0.00% New 134,016 $736K
Graham Capital Management, L.P. 0.03% Add +89.2% 133,668 $734K
Russell Investments Group, Ltd. 0.00% Add +632.6% 131,687 $723K
Globeflex Capital L P 0.06% No change 125,210 $687K
Occudo Quantitative Strategies LP 0.09% Add +132.8% 120,424 $672K
Roundview Capital LLC 0.05% No change 120,000 $659K
Citigroup Inc. 0.00% Reduce -10.8% 118,208 $649K
Brown Advisory Inc. 0.00% Reduce -39.7% 114,698 $630K
Principal Financial Group Inc. 0.00% Add +0.5% 113,746 $624K
Franklin Resources Inc. 0.00% Add +451.8% 107,936 $593K
Creative Planning 0.00% Add +16.9% 106,732 $586K
Stonepine Capital Management, LLC 0.55% Reduce -43.9% 102,265 $561K
Alpine Global Management, LLC 0.16% Reduce -37.5% 100,000 $549K
Sei Investments Co. 0.00% New 97,491 $535K
Point72 Asset Management 0.00% New 88,373 $485K
Bantamac Capital, LLC 0.22% New 85,111 $467K
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Add +4.5% 83,982 $461K
MetLife Investment Management, LLC 0.00% Reduce -6.5% 81,769 $449K
HRT Financial LP 0.00% Add +292.4% 81,112 $445K
Orbimed Advisors LLC 0.01% No change 80,420 $442K
EntryPoint Capital, LLC 0.19% Add +43.5% 75,706 $416K
Sigma Planning Corp 0.01% Reduce -3.9% 73,950 $406K
Quarry LP 0.10% New 70,751 $388K
SG Americas Securities, LLC 0.00% Reduce -25.5% 70,499 $387K
Wells Fargo & Company 0.00% Reduce -11.6% 69,881 $384K
Corebridge Financial, Inc. 0.00% Reduce -1.5% 68,698 $377K
Cwm, LLC 0.00% Add +79.3% 66,972 $368K
GPS Wealth Strategies Group, LLC 0.05% No change 66,925 $367K
Centiva Capital, LP 0.02% New 62,053 $341K
STRS Ohio 0.00% Reduce -3.5% 60,900 $334K
Bayesian Capital Management, LP 0.05% New 59,300 $326K
Quantbot Technologies LP 0.01% New 54,107 $297K
Mach-1 Financial Group, LLC 0.09% New 52,530 $288K
Chevy Chase Trust Holdings, LLC 0.00% No change 51,243 $281K
Manufacturers Life Insurance Company, The 0.00% Reduce -4.0% 50,910 $279K
Intech Investment Management LLC 0.00% Reduce -15.0% 50,107 $275K
Weiss Asset Management LP 0.01% No change 50,001 $275K
Virtus Investment Advisers, LLC 0.07% New 48,288 $265K
Harvest Investment Services, LLC 0.07% New 46,457 $255K
Cetera Investment Advisers 0.00% New 44,597 $245K
Y-Intercept (Hong Kong) Ltd 0.02% New 44,518 $244K
New York State Common Retirement Fund 0.00% Add +90.3% 43,422 $238K
LJI Wealth Management, LLC 0.05% No change 42,350 $233K
Mariner, LLC 0.00% Add +36.5% 41,354 $227K
Verition Fund Management LLC 0.00% Reduce -51.5% 41,290 $227K
Goldstein Advisors, LLC 0.03% Add +5.8% 40,000 $220K
Voya Investment Management LLC 0.00% Reduce -11.1% 39,795 $218K
Osaic Holdings, Inc. 0.00% Reduce -11.2% 38,935 $214K
LPL Financial LLC 0.00% Add +4.9% 38,827 $213K
State Board of Administration of Florida Retirement System 0.00% No change 37,970 $208K
ProShare Advisors LLC 0.00% Reduce -20.4% 37,081 $204K
Cambridge Investment Research Advisors, Inc. 0.00% No change 34,542 $190K
Balyasny Asset Management L.P. 0.00% Add +100.9% 34,454 $189K
Cerity Partners LLC 0.00% Add +107.3% 31,851 $175K
Police & Firemen's Retirement System of New Jersey 0.00% No change 31,659 $174K
Wealth Enhancement Advisory Services, LLC 0.00% Add +92.1% 31,254 $172K
Cibc World Markets Corp. 0.00% Add +137.1% 31,115 $171K
Quadrature Capital Ltd 0.00% New 31,133 $171K
Caxton Associates LLP 0.01% — 30,938 $170K
China Universal Asset Management Co., Ltd. 0.02% Reduce -5.4% 29,903 $164K
Point72 Asia (Singapore) Pte. Ltd. 0.04% New 27,268 $150K
Inceptionr LLC 0.04% New 26,494 $145K
Asset Management Group, Inc. 0.03% No change 26,480 $145K
Apollon Wealth Management, LLC 0.00% Add +19.8% 24,160 $133K
Sunpointe, LLC 0.06% No change 21,000 $115K
State of Wisconsin Investment Board 0.00% New 20,275 $111K
Profund Advisors LLC 0.00% Reduce -12.1% 20,192 $111K
Acadian Asset Management LLC 0.00% New 17,596 $96K
Victory Capital Management Inc. 0.00% Reduce -2.1% 17,124 $94K
Susquehanna Fundamental Investments, LLC 0.00% Reduce -13.3% 17,087 $94K
Gateway Wealth Partners, LLC 0.02% New 16,800 $92K
Aigen Investment Management, LP 0.01% New 16,769 $92K
Van Hulzen Asset Management, LLC 0.01% Reduce -9.7% 16,276 $89K
Gotham Asset Management 0.00% New 16,232 $89K
HSBC Holdings PLC 0.00% Reduce -0.7% 16,205 $88K
Squarepoint Ops LLC 0.00% Reduce -60.8% 15,995 $88K
R Squared Ltd 0.09% Add +27.7% 15,730 $86K
Landscape Capital Management, L.L.C. 0.01% New 15,709 $86K
Axq Capital, LP 0.03% New 15,348 $84K
Pallas Capital Advisors LLC 0.00% New 15,343 $84K
Rafferty Asset Management, LLC 0.00% Reduce -15.3% 15,003 $82K
Sherbrooke Park Advisers LLC 0.04% Reduce -36.2% 14,877 $82K
Ameritas Investment Partners, Inc. 0.00% No change 14,205 $78K
Veery Capital, LLC 0.03% No change 14,163 $78K
Oxford Asset Management LLP 0.04% New 13,901 $76K
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management 0.00% No change 13,650 $75K
Captrust Financial Advisors 0.00% New 11,782 $65K
FNY Investment Advisers, LLC 0.04% New 11,500 $63K
Lazard Asset Management LLC 0.00% Reduce -94.8% 11,182 $61K
FORA Capital, LLC 0.01% New 11,017 $60K
Xponance LLC 0.00% New 10,319 $57K
California State Teachers Retirement System 0.00% No change 10,161 $56K
Apella Capital, LLC 0.00% New 10,000 $43K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +0.4% 4,988 $28K
CIBC Private Wealth Group LLC 0.00% No change 6,664 $28K
Amalgamated Bank 0.00% Add +5.2% 4,834 $27K
GF Fund Management Co. LTD. 0.00% Add +21.9% 3,817 $21K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% New 3,664 $20K
Webster Bank, N. A. 0.00% New 3,000 $16K
Northwestern Mutual Wealth Management Co. 0.00% New 2,789 $15K
Creative Financial Designs Inc. 0.00% No change 2,055 $11K
SBI Securities Co., Ltd. 0.00% Reduce -0.5% 1,907 $10K
Tower Research Capital LLC (TRC) 0.00% Reduce -56.4% 1,717 $9K
Fortitude Family Office, LLC 0.00% No change 1,671 $9K
Allworth Financial LP 0.00% No change 1,896 $8K
EverSource Wealth Advisors, LLC 0.00% Add +168.1% 1,418 $8K
True Wealth Design, LLC 0.00% Add +30.8% 1,205 $7K
Hillsdale Investment Management Inc. 0.00% New 1,100 $6K
Tsfg, LLC 0.00% Add +49.4% 1,058 $6K
Activest Wealth Management 0.00% No change 1,000 $5K
Nisa Investment Advisors, LLC 0.00% No change 719 $4K
Rothschild Investment LLC 0.00% Reduce -6.7% 420 $2K
MassMutual Private Wealth & Trust, FSB 0.00% New 420 $2K
Signaturefd, LLC 0.00% New 391 $2K
Covestor Ltd 0.00% New 379 $2K
Daiwa Securities Group Inc. 0.00% No change 404 $2K
Caitong International Asset Management Co., Ltd 0.00% Add +54.3% 287 $2K
Spurstone Advisory Services, LLC 0.02% No change 200 $1K
Farther Finance Advisors, LLC 0.00% No change 181 $919
Parkside Financial Bank & Trust 0.00% New 155 $848
Sterling Capital Management LLC 0.00% No change 142 $780
PNC Financial Services Group, Inc. 0.00% New 102 $560
Stephens Consulting, LLC 0.00% New 65 $357
WealthTrak Capital Management LLC 0.00% No change 40 $220
Wilmington Savings Fund Society, FSB 0.00% No change 40 $220
Lindbrook Capital, LLC 0.00% New 28 $154
IFP Advisors, Inc 0.00% No change 26 $143

"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.