Xeris Biopharma HoldingsXERS
13F holders, Q1 2026 (March 31)237holders +13
41new positions
29sold out
7famous investors
$5.81avg. 13F price*
At the end of Q1 2026, 237 institutions reported holding Xeris Biopharma Holdings Inc. (XERS) in their 13F filings, up 13 from Q4 2025. 41 opened new positions and 29 sold out. The largest holders were BlackRock, Inc. ($75.1M), D. E. Shaw & Co. ($45.2M) and Vanguard Capital Management LLC ($40.5M). 7 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio).
- Company
- Xeris Biopharma Holdings Inc.
- CUSIP
- 98422E103
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 41 | $23.3M |
| Exits | 29 | $28.9M |
All 13F filers, Q4 2025 → Q1 2026: 16,369,860 shares bought and 10,140,299 shares sold, net +6,229,561 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 237 holders
| BlackRock, Inc. | 0.00% | Add +2.4% | 12,945,785 | $75.1M |
| D. E. Shaw & Co. | 0.04% | Add +2.8% | 7,788,811 | $45.2M |
| Vanguard Capital Management LLC | 0.00% | — | 6,980,882 | $40.5M |
| State Street Corp. | 0.00% | Add +13.2% | 4,658,174 | $27.0M |
| Geode Capital Management, LLC | 0.00% | Add +0.3% | 4,290,629 | $24.9M |
| Qube Research & Technologies Ltd | 0.03% | Add +17.6% | 4,114,425 | $23.9M |
| Rosalind Advisors, Inc. | 7.68% | Add +53.0% | 3,231,700 | $18.7M |
| Nuveen, LLC | 0.00% | Add +3.9% | 2,916,598 | $16.9M |
| Vanguard Portfolio Management LLC | 0.00% | — | 2,665,608 | $15.5M |
| Morgan Stanley | 0.00% | Reduce -5.0% | 2,572,654 | $14.9M |
| Millennium Management | 0.01% | Add +163.8% | 2,265,974 | $13.1M |
| Wellington Management Group LLP | 0.00% | Reduce -5.0% | 2,171,354 | $12.6M |
| Two Sigma Investments, LP | 0.01% | Add +11.1% | 1,924,202 | $11.2M |
| Armistice Capital, LLC | 0.37% | New | 1,909,838 | $11.1M |
| Legal & General Group Plc | 0.00% | Add +36.7% | 1,908,289 | $11.1M |
| Parkman Healthcare Partners LLC | 1.03% | Add +1.8% | 1,721,264 | $10.0M |
| UBS Group AG | 0.00% | Add +173.6% | 1,646,378 | $9.5M |
| Goldman Sachs Group Inc. | 0.00% | Add +2.9% | 1,613,650 | $9.4M |
| Northern Trust Corp. | 0.00% | Add +4.2% | 1,444,617 | $8.4M |
| AQR Capital Management | 0.00% | Add +45.6% | 1,394,376 | $8.1M |
| Voss Capital, LP | 0.46% | Add +273.1% | 1,386,927 | $8.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.1% | 1,359,657 | $7.9M |
| CenterBook Partners LP | 0.39% | Reduce -10.3% | 1,248,621 | $7.2M |
| Kennedy Capital Management LLC | 0.15% | Add +2.2% | 1,240,692 | $7.2M |
| Algert Global LLC | 0.10% | Add +61.0% | 1,156,958 | $6.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 1,133,902 | $6.6M |
| Knott David M Jr | 3.66% | Add +9.3% | 1,060,000 | $6.1M |
| Ishara Investments LP | 6.00% | Add +28.1% | 1,025,000 | $5.9M |
| Granahan Investment Management, LLC | 0.26% | Reduce -24.6% | 921,854 | $5.3M |
| Driehaus Capital Management LLC | 0.04% | Reduce -69.7% | 902,740 | $5.2M |
| Bank of America Corp. | 0.00% | Add +21.8% | 874,397 | $5.1M |
| Federated Hermes, Inc. | 0.01% | Add +0.2% | 856,813 | $5.0M |
| Trexquant Investment LP | 0.04% | Add +290.1% | 833,217 | $4.8M |
| Essex Investment Management Co. LLC | 0.69% | Add +1.8% | 747,769 | $4.3M |
| Jane Street Group, LLC | 0.00% | Add +308.1% | 725,616 | $4.2M |
| Citadel Advisors | 0.00% | Add +66.3% | 681,634 | $4.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.5% | 668,074 | $3.9M |
| Voya Investment Management LLC | 0.00% | Add +36.4% | 625,310 | $3.6M |
| Deutsche Bank AG | 0.00% | Reduce -33.8% | 623,012 | $3.6M |
| Squarepoint Ops LLC | 0.01% | Add +27.3% | 614,550 | $3.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -31.6% | 612,479 | $3.4M |
| Sei Investments Co. | 0.00% | Add +45.0% | 579,210 | $3.4M |
| FMR LLC | 0.00% | Add +16.7% | 513,076 | $3.0M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.00% | Reduce -13.7% | 464,084 | $2.7M |
| Renaissance Technologies | 0.00% | Reduce -26.9% | 452,860 | $2.6M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.8% | 426,285 | $2.5M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -61.5% | 407,625 | $2.4M |
| Russell Investments Group, Ltd. | 0.00% | Add +5.3% | 384,195 | $2.2M |
| IHT Wealth Management, LLC | 0.05% | Add +42.9% | 376,476 | $2.2M |
| Canada Pension Plan Investment Board | 0.00% | Reduce -4.0% | 374,800 | $2.2M |
| Voloridge Investment Management, LLC | 0.01% | Reduce -54.4% | 370,116 | $2.1M |
| Swiss National Bank | 0.00% | Add +3.1% | 328,300 | $1.9M |
| State of Wisconsin Investment Board | 0.00% | Reduce -13.7% | 308,546 | $1.8M |
| Schonfeld Strategic Advisors LLC | 0.01% | Add +26.3% | 296,431 | $1.7M |
| Janus Henderson Group PLC | 0.00% | Add +322.8% | 295,489 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Add +143.8% | 286,071 | $1.7M |
| Man Group plc | 0.00% | Add +478.6% | 276,422 | $1.6M |
| BNP Paribas Financial Markets | 0.00% | Add +1.7% | 262,787 | $1.5M |
| Apella Capital, LLC | 0.02% | Reduce -4.1% | 235,897 | $1.5M |
| Royce & Associates LP | 0.01% | New | 256,087 | $1.5M |
| Rice Hall James & Associates, LLC | 0.08% | New | 251,066 | $1.5M |
| Legato Capital Management LLC | 0.12% | Reduce -1.4% | 234,144 | $1.4M |
| Group One Trading LLC | 0.04% | Add +76.5% | 218,145 | $1.3M |
| T. Rowe Price Associates Inc. | 0.00% | Add +20.5% | 209,034 | $1.2M |
| Principal Financial Group Inc. | 0.00% | Add +38.5% | 208,507 | $1.2M |
| Raymond James Financial Inc. | 0.00% | Reduce -1.5% | 208,273 | $1.2M |
| F/m Investments LLC | 0.08% | New | 207,543 | $1.2M |
| Emerald Mutual Fund Advisers Trust | 0.06% | New | 207,543 | $1.2M |
| Caption Management, LLC | 0.06% | New | 205,000 | $1.2M |
| Commonwealth Equity Services, LLC | 0.00% | Add +2.7% | 203,116 | $1.2M |
| Alliancebernstein L.P. | 0.00% | Add +0.3% | 145,336 | $1.1M |
| Rhumbline Advisers | 0.00% | Add +0.8% | 191,067 | $1.1M |
| Engineers Gate Manager LP | 0.01% | Add +107.9% | 185,911 | $1.1M |
| California State Teachers Retirement System | 0.00% | Add +19.3% | 180,339 | $1.0M |
| HRT Financial LP | 0.00% | Reduce -48.5% | 171,102 | $992K |
| Y-Intercept (Hong Kong) Ltd | 0.02% | Add +78.5% | 161,793 | $938K |
| Ameriprise Financial Inc. | 0.00% | Reduce -0.9% | 142,148 | $824K |
| Barclays PLC | 0.00% | Reduce -61.8% | 138,553 | $804K |
| Swiss Life Asset Management Ltd | 0.00% | Add +27.5% | 33,232 | $789K |
| Arrowstreet Capital, Limited Partnership | 0.00% | Reduce -37.7% | 133,760 | $776K |
| Creative Planning | 0.00% | Add +14.4% | 133,285 | $773K |
| Diadema Partners LP | 0.32% | Reduce -22.2% | 132,746 | $770K |
| Quarry LP | 0.15% | Add +56.3% | 125,000 | $725K |
| Globeflex Capital L P | 0.11% | No change | 123,184 | $714K |
| SG Americas Securities, LLC | 0.00% | Add +10.7% | 121,911 | $707K |
| Tudor Investment Corporation | 0.00% | Add +384.1% | 107,414 | $623K |
| Panagora Asset Management Inc. | 0.00% | New | 104,744 | $608K |
| Palo Alto Investors LP | 0.09% | New | 104,410 | $606K |
| WINTON GROUP Ltd | 0.02% | Add +61.4% | 104,240 | $605K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 103,555 | $601K |
| Invesco Ltd. | 0.00% | Reduce -7.9% | 103,294 | $599K |
| Gsa Capital Partners LLP | 0.04% | Add +192.6% | 101,438 | $588K |
| Twinbeech Capital LP | 0.06% | New | 97,200 | $564K |
| Round Rock Advisors LLC | 0.09% | No change | 96,816 | $562K |
| EntryPoint Capital, LLC | 0.16% | Add +41.3% | 96,210 | $558K |
| LPL Financial LLC | 0.00% | Add +10.6% | 93,861 | $544K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +41.9% | 93,302 | $541K |
| Jefferies Financial Group Inc. | 0.01% | No change | 87,800 | $509K |
| Citigroup Inc. | 0.00% | Reduce -11.6% | 87,325 | $506K |
| Thompson Siegel & Walmsley LLC | 0.01% | Reduce -14.4% | 86,320 | $501K |
"% of holder's portfolio" is XERS's weight in each manager's 13F, not the share of Xeris Biopharma Holdings Inc. the manager owns.