Artal Group S.A.
In its 13F for Q2 2024 (holdings as of June 30, 2024, filed August 14, 2024), Artal Group S.A. reported 108 stock positions worth $3.9 billion. Its top holding was Cava (CAVA) at 56.0% of the portfolio, followed by Lexicon Pharmaceuticals (LXRX, 7.6%) and Scholar Rock (SRRK, 2.4%). Compared with Q1 2024, it opened 21 new positions, sold out of 20, added to 28 and reduced 27. The biggest buy was a new position in Avidity Biosciences (RNAM) and the biggest sale Kymera Therapeutics (KYMR, shares −1%).
- Most Recent 13F
- Q2 2026
- Location
- LUXEMBOURG, N4
- CIK
- 0001053906
- Portfolio Value
- $3.9B (Q2 2024)
- SEC Filing
- 0001053906-24-000009 ↗ filed Aug 14, 2024
Holdings Value
Holdings 108 stocks · $3.9B
| CAVA Cava Group Inc. | 55.98% | 23,507,990 | $2.2B | Reduce -11.3% |
| LXRX Lexicon Pharmaceuticals Inc. | 7.55% | 175,099,384 | $294.2M | Add +49.0% |
| SRRK Scholar Rock Holding Corp. | 2.41% | 11,259,438 | $93.8M | No change |
| KYMR Kymera Therapeutics Inc. | 2.30% | 3,005,610 | $89.7M | Reduce -0.7% |
| MORF Morphic Holding Inc. | 2.21% | 2,525,998 | $86.1M | Add +14.1% |
| ARWR Arrowhead Pharmaceuticals Inc. | 2.13% | 3,189,389 | $82.9M | Add +5.0% |
| APLS Apellis Pharmaceuticals Inc. | 1.44% | 1,467,080 | $56.3M | Add +11.5% |
| DYN Dyne Therapeutics Inc. | 1.37% | 1,516,960 | $53.5M | Reduce -0.1% |
| SLN Silence Therapeutics PLC-ADR | 1.36% | 2,779,619 | $52.8M | No change |
| SWTX Springworks Therapeutics Inc. | 1.27% | 1,313,026 | $49.5M | Reduce -7.2% |
| CRNX Crinetics Pharmaceuticals Inc. | 1.23% | 1,066,064 | $47.7M | Reduce -23.3% |
| MRUS Merus NV | 1.16% | 760,355 | $45.0M | Add +67.1% |
| ONC Beone Medicines Ltd.-ADR filed as BEIGENE LTD | 1.11% | 303,369 | $43.3M | Reduce -25.1% |
| RVMD Revolution Medicines Inc. | 1.01% | 1,015,776 | $39.4M | Reduce -23.0% |
| KURA Kura Oncology Inc. | 0.96% | 1,819,884 | $37.5M | Reduce -5.2% |
| VERA Vera Therapeutics Inc. | 0.85% | 915,974 | $33.1M | Add +81.0% |
| NMRA Neumora Therapeutics Inc. | 0.71% | 2,824,052 | $27.8M | Reduce -3.4% |
| CYTK Cytokinetics Inc. | 0.69% | 494,421 | $26.8M | Reduce -2.4% |
| RNAM Avidity Biosciences Inc. | 0.69% | 655,555 | $26.8M | New |
| IGMS Igm Biosciences Inc. | 0.59% | 3,330,422 | $22.9M | Add +8.1% |
| WVE Wave Life Sciences Ltd. | 0.58% | 4,566,251 | $22.8M | Add +12.7% |
| ERAS Erasca Inc. | 0.58% | 9,630,810 | $22.7M | Add +104.0% |
| TNGX Tango Therapeutics Inc. | 0.56% | 2,519,841 | $21.6M | Add +14.8% |
| PRTA Prothena Corp. PLC | 0.53% | 1,001,360 | $20.7M | No change |
| CNTA Centessa Pharmaceuticals Ltd. | 0.49% | 2,112,500 | $19.1M | Add +49.6% |
| CGEM Cullinan Therapeutics Inc. | 0.47% | 1,057,949 | $18.5M | New |
| NAMS Newamsterdam Pharma Co. NV | 0.39% | 800,000 | $15.4M | No change |
| XENE Xenon Pharmaceuticals Inc. | 0.38% | 381,554 | $14.9M | Add +50.6% |
| EWTX Edgewise Therapeutics Inc. | 0.38% | 811,718 | $14.6M | No change |
| SLDB Solid Biosciences Inc. | 0.36% | 2,500,000 | $14.2M | No change |
| KRRO Korro Bio Inc. | 0.36% | 413,072 | $14.0M | Reduce -1.5% |
| ASND Ascendis Pharma A/S | 0.35% | 101,100 | $13.8M | New |
| AGEN Agenus Inc. | 0.33% | 775,000 | $13.0M | Reduce -0.8% |
| SYRS Syros Pharmaceuticals Inc. | 0.33% | 2,505,013 | $12.9M | No change |
| GOSS Gossamer Bio Inc. | 0.31% | 13,308,968 | $12.0M | No change |
| DNLI Denali Therapeutics Inc. | 0.30% | 502,899 | $11.7M | No change |
| RARE Ultragenyx Pharmaceutical Inc. | 0.29% | 275,000 | $11.3M | Add +54.5% |
| BHVN Biohaven Ltd. | 0.27% | 306,703 | $10.6M | New |
| TSHA Taysha Gene Therapies Inc. | 0.25% | 4,354,214 | $9.8M | Add +18.1% |
| LXEO Lexeo Therapeutics Inc. | 0.25% | 603,435 | $9.7M | Reduce -24.7% |
| SLRN Acelyrin Inc. | 0.23% | 2,020,888 | $8.9M | Reduce -16.0% |
| JANX Janux Therapeutics Inc. | 0.22% | 203,000 | $8.5M | Add +306.0% |
| RNAC Cartesian Therapeutics Inc. | 0.21% | 304,554 | $8.2M | New |
| RAPP Rapport Therapeutics Inc. | 0.21% | 350,000 | $8.1M | New |
| IOVA Iovance Biotherapeutics Inc. | 0.21% | 1,011,500 | $8.1M | New |
| GBIO Generation Bio Co. | 0.20% | 2,830,591 | $8.0M | No change |
| SEER Seer Inc. | 0.20% | 4,750,000 | $8.0M | No change |
| VIGL Vigil Neuroscience Inc. | 0.19% | 1,828,691 | $7.3M | Add +1.0% |
| MIND MEDICINE MINDMED INC | 0.19% | 1,007,875 | $7.3M | New |
| SE Sea Ltd.-ADR | 0.18% | 97,500 | $7.0M | Reduce -59.0% |
| PDD PDD Holdings Inc. | 0.16% | 45,500 | $6.0M | Reduce -19.5% |
| NVDA Nvidia Corp. | 0.14% | 43,000 | $5.3M | Add +126.3% |
| MSFT Microsoft Corp. | 0.13% | 11,300 | $5.1M | Add +352.0% |
| V Visa Inc. Class A | 0.13% | 19,000 | $5.0M | Add +660.0% |
| BDTX Black Diamond Therapeutics I | 0.13% | 1,046,517 | $4.9M | No change |
| DT Dynatrace Inc. | 0.13% | 109,000 | $4.9M | Add +202.8% |
| ALLOVIR INC | 0.12% | 6,597,167 | $4.8M | No change |
| APLT Applied Therapeutics Inc. | 0.12% | 1,009,500 | $4.7M | No change |
| TSM Taiwan Semiconductor-SP ADR | 0.12% | 26,000 | $4.5M | Reduce -18.8% |
| FHTX Foghorn Therapeutics Inc. | 0.11% | 720,720 | $4.1M | No change |
| DDOG Datadog Inc. Class A | 0.10% | 28,925 | $3.8M | Add +201.3% |
| ANRO Alto Neuroscience Inc. | 0.10% | 350,000 | $3.7M | No change |
| AMZN Amazon.com Inc. | 0.10% | 19,250 | $3.7M | Add +60.4% |
| FATE Fate Therapeutics Inc. | 0.09% | 1,032,500 | $3.4M | Add +186.6% |
| HOOKIPA PHARMA INC | 0.09% | 5,666,410 | $3.4M | No change |
| ADCT Adc Therapeutics SA | 0.08% | 1,018,461 | $3.2M | New |
| BEKE Ke Holdings Inc.-ADR filed as KE HLDGS INC | 0.08% | 225,000 | $3.2M | Reduce -18.2% |
| RGNX Regenxbio Inc. | 0.08% | 250,000 | $2.9M | No change |
| OMGAQ Omega Therapeutics Inc. | 0.07% | 1,323,530 | $2.7M | No change |
| ELEV Elevation Oncology Inc. | 0.07% | 1,013,015 | $2.7M | Reduce -33.0% |
| KVUE Kenvue Inc. | 0.06% | 137,000 | $2.5M | New |
| SGMT Sagimet Biosciences Inc. Class A | 0.06% | 724,771 | $2.5M | No change |
| GLYCOMIMETICS INC | 0.06% | 8,589,064 | $2.4M | No change |
| PCOR Procore Technologies Inc. | 0.06% | 32,300 | $2.1M | Add +240.0% |
| NOW ServiceNow Inc. | 0.05% | 2,500 | $2.0M | New |
| OVID Ovid Therapeutics Inc. | 0.05% | 2,500,000 | $1.9M | No change |
| GRITSTONE BIO INC | 0.05% | 3,030,952 | $1.9M | Add +194.0% |
| PEPG Pepgen Inc. | 0.05% | 113,317 | $1.8M | Reduce -43.3% |
| PANW Palo Alto Networks Inc. | 0.04% | 4,500 | $1.5M | Add +50.0% |
| KYTX Kyverna Therapeutics Inc. | 0.04% | 200,000 | $1.5M | No change |
| QCOM Qualcomm Inc. | 0.04% | 7,500 | $1.5M | New |
| AEROVATE THERAPEUTICS INC | 0.03% | 809,600 | $1.3M | New |
| GOOGL Alphabet Inc. Class A | 0.03% | 7,000 | $1.3M | No change |
| MGX Metagenomi Therapeutics Inc. | 0.03% | 300,000 | $1.2M | No change |
| TRML Tourmaline Bio Inc. | 0.03% | 91,426 | $1.2M | Reduce -70.9% |
| RBRK Rubrik Inc. Class A | 0.03% | 35,000 | $1.1M | New |
| KRON Kronos Bio Inc. | 0.03% | 842,954 | $1.0M | No change |
| MDB Mongodb Inc. | 0.03% | 4,021 | $1.0M | Add +101.0% |
| EDU New Oriental Educatio-SP ADR | 0.02% | 12,500 | $972K | Reduce -16.7% |
| BZ Kanzhun Ltd. - ADR | 0.02% | 50,000 | $941K | New |
| FROG Jfrog Ltd. | 0.02% | 25,000 | $939K | New |
| PYPL PayPal Holdings Inc. | 0.02% | 15,000 | $870K | Add +50.0% |
| INTC Intel Corp. | 0.02% | 25,000 | $774K | New |
| IRWD Ironwood Pharmaceuticals Inc. | 0.02% | 110,532 | $721K | No change |
| PEGA Pegasystems Inc. | 0.02% | 11,500 | $696K | No change |
| SNOW Snowflake Inc. | 0.02% | 5,051 | $682K | Reduce -22.3% |
| ACHL Achilles Therapeutics PL-ADR | 0.02% | 755,375 | $616K | No change |
| CFLT Confluent Inc. Class A | 0.01% | 19,000 | $561K | No change |
| CCC CCC Intelligent Solutions Ho | 0.01% | 50,000 | $556K | New |
| META Meta Platforms Inc. Class A | 0.01% | 1,100 | $555K | New |
Options reported separately and not counted above: ARWR calls ($26.0M), PYPL calls ($1.5M), GOSS calls ($186K).
Other holdings (1): bonds, preferreds, convertibles and warrants · $4K (not counted above)
| Security | Class | Shares / Principal | Value | Change |
|---|---|---|---|---|
| PERCEPTION CAPITAL CORP III | *W EXP 99/99/999 | 126,666 | $4K | New |
Total filed on the 13F, all lines: $3.9B.
Portfolio Sells Q1 2024 → Q2 2024
| KYMR Kymera Therapeutics Inc. | Reduce -0.7% | 2.30% | −0.83 |
| MDGL Madrigal Pharmaceuticals Inc. | Sold out | 0.00% | −0.76 |
| KRRO Korro Bio Inc. | Reduce -1.5% | 0.36% | −0.61 |
| VKTX Viking Therapeutics Inc. | Sold out | 0.00% | −0.54 |
| SWTX Springworks Therapeutics Inc. | Reduce -7.2% | 1.27% | −0.53 |
| ONC Beone Medicines Ltd.-ADR | Reduce -25.1% | 1.11% | −0.52 |
| CRNX Crinetics Pharmaceuticals Inc. | Reduce -23.3% | 1.23% | −0.45 |
| ALPN Alpine Immune Sciences Inc. | Sold out | 0.00% | −0.41 |
| NMRA Neumora Therapeutics Inc. | Reduce -3.4% | 0.71% | −0.32 |
| ATXS Astria Therapeutics Inc. | Sold out | 0.00% | −0.32 |
| FOLD Amicus Therapeutics Inc. | Sold out | 0.00% | −0.31 |
| CLDX Celldex Therapeutics Inc. | Sold out | 0.00% | −0.27 |
| APGE Apogee Therapeutics Inc. | Sold out | 0.00% | −0.26 |
| CYTK Cytokinetics Inc. | Reduce -2.4% | 0.69% | −0.23 |
| SLRN Acelyrin Inc. | Reduce -16.0% | 0.23% | −0.19 |
| GPCR Structure Therapeutics Inc. | Sold out | 0.00% | −0.17 |
| AXSM Axsome Therapeutics Inc. | Sold out | 0.00% | −0.16 |
| TRML Tourmaline Bio Inc. | Reduce -70.9% | 0.03% | −0.16 |
| RNAC Cartesian Therapeutics Inc. | Sold out | 0.00% | −0.15 |
| SE Sea Ltd.-ADR | Reduce -59.0% | 0.18% | −0.15 |
| ELEV Elevation Oncology Inc. | Reduce -33.0% | 0.07% | −0.13 |
| GERN Geron Corp. | Sold out | 0.00% | −0.11 |
| STOK Stoke Therapeutics Inc. | Sold out | 0.00% | −0.10 |
| KURA Kura Oncology Inc. | Reduce -5.2% | 0.96% | −0.09 |
| RPTX Repare Therapeutics Inc. | Sold out | 0.00% | −0.09 |
| RVMD Revolution Medicines Inc. | Reduce -23.0% | 1.01% | −0.08 |
| LXEO Lexeo Therapeutics Inc. | Reduce -24.7% | 0.25% | −0.08 |
| ADAG Adagene Inc.-ADR | Sold out | 0.00% | −0.07 |
| VOR Vor Biopharma Inc. | Sold out | 0.00% | −0.06 |
| AAPL Apple Inc. | Sold out | 0.00% | −0.04 |
| PEPG Pepgen Inc. | Reduce -43.3% | 0.05% | −0.03 |
| ADBE Adobe Inc. | Reduce -71.0% | 0.01% | −0.03 |
| AMD Advanced Micro Devices | Sold out | 0.00% | −0.02 |
| BEKE Ke Holdings Inc.-ADR | Reduce -18.2% | 0.08% | −0.02 |
| PDD PDD Holdings Inc. | Reduce -19.5% | 0.16% | −0.01 |
| INTA Intapp Inc. | Reduce -55.9% | 0.01% | −0.01 |
| CWAN Clearwater Analytics HDS-A | Sold out | 0.00% | −0.01 |
| HIPO Hippo Holdings Inc. | Sold out | 0.00% | −0.01 |
| SNOW Snowflake Inc. | Reduce -22.3% | 0.02% | −0.01 |
| DLO Dlocal Ltd. | Reduce -65.1% | 0.00% | −0.01 |
| EDU New Oriental Educatio-SP ADR | Reduce -16.7% | 0.02% | −0.01 |
| CYCLERION THERAPEUTICS INC | Reduce -15.3% | 0.01% | −0.00 |
| INKT Mink Therapeutics Inc. | Sold out | 0.00% | 0.00 |
| TSM Taiwan Semiconductor-SP ADR | Reduce -18.8% | 0.12% | +0.00 |
| AGEN Agenus Inc. | Reduce -0.8% | 0.33% | +0.10 |
| DYN Dyne Therapeutics Inc. | Reduce -0.1% | 1.37% | +0.26 |
| CAVA Cava Group Inc. | Reduce -11.3% | 55.98% | +8.12 |
Portfolio Buys Q1 2024 → Q2 2024
| RNAM Avidity Biosciences Inc. | New | 0.69% | +0.69 |
| MRUS Merus NV | Add +67.1% | 1.16% | +0.63 |
| CGEM Cullinan Therapeutics Inc. | New | 0.47% | +0.47 |
| ASND Ascendis Pharma A/S | New | 0.35% | +0.35 |
| ERAS Erasca Inc. | Add +104.0% | 0.58% | +0.33 |
| VERA Vera Therapeutics Inc. | Add +81.0% | 0.85% | +0.29 |
| LXRX Lexicon Pharmaceuticals Inc. | Add +49.0% | 7.55% | +0.28 |
| BHVN Biohaven Ltd. | New | 0.27% | +0.27 |
| RNAC Cartesian Therapeutics Inc. | New | 0.21% | +0.21 |
| RAPP Rapport Therapeutics Inc. | New | 0.21% | +0.21 |
| IOVA Iovance Biotherapeutics Inc. | New | 0.21% | +0.21 |
| MORF Morphic Holding Inc. | Add +14.1% | 2.21% | +0.20 |
| MIND MEDICINE MINDMED INC | New | 0.19% | +0.19 |
| JANX Janux Therapeutics Inc. | Add +306.0% | 0.22% | +0.17 |
| V Visa Inc. Class A | Add +660.0% | 0.13% | +0.11 |
| TNGX Tango Therapeutics Inc. | Add +14.8% | 0.56% | +0.11 |
| MSFT Microsoft Corp. | Add +352.0% | 0.13% | +0.10 |
| XENE Xenon Pharmaceuticals Inc. | Add +50.6% | 0.38% | +0.10 |
| NVDA Nvidia Corp. | Add +126.3% | 0.14% | +0.09 |
| ADCT Adc Therapeutics SA | New | 0.08% | +0.08 |
| DT Dynatrace Inc. | Add +202.8% | 0.13% | +0.08 |
| CNTA Centessa Pharmaceuticals Ltd. | Add +49.6% | 0.49% | +0.08 |
| RARE Ultragenyx Pharmaceutical Inc. | Add +54.5% | 0.29% | +0.08 |
| DDOG Datadog Inc. Class A | Add +201.3% | 0.10% | +0.07 |
| KVUE Kenvue Inc. | New | 0.06% | +0.06 |
| NOW ServiceNow Inc. | New | 0.05% | +0.05 |
| AMZN Amazon.com Inc. | Add +60.4% | 0.10% | +0.04 |
| QCOM Qualcomm Inc. | New | 0.04% | +0.04 |
| PCOR Procore Technologies Inc. | Add +240.0% | 0.06% | +0.03 |
| AEROVATE THERAPEUTICS INC | New | 0.03% | +0.03 |
| VIGL Vigil Neuroscience Inc. | Add +1.0% | 0.19% | +0.03 |
| RBRK Rubrik Inc. Class A | New | 0.03% | +0.03 |
| BZ Kanzhun Ltd. - ADR | New | 0.02% | +0.02 |
| FROG Jfrog Ltd. | New | 0.02% | +0.02 |
| INTC Intel Corp. | New | 0.02% | +0.02 |
| FATE Fate Therapeutics Inc. | Add +186.6% | 0.09% | +0.02 |
| PANW Palo Alto Networks Inc. | Add +50.0% | 0.04% | +0.02 |
| CCC CCC Intelligent Solutions Ho | New | 0.01% | +0.01 |
| META Meta Platforms Inc. Class A | New | 0.01% | +0.01 |
| RELY Remitly Global Inc. | New | 0.01% | +0.01 |
| MDB Mongodb Inc. | Add +101.0% | 0.03% | +0.01 |
| PYPL PayPal Holdings Inc. | Add +50.0% | 0.02% | +0.01 |
| DELL Dell Technologies -C | New | 0.00% | +0.00 |
| GRITSTONE BIO INC | Add +194.0% | 0.05% | −0.02 |
| TSHA Taysha Gene Therapies Inc. | Add +18.1% | 0.25% | −0.02 |
| WVE Wave Life Sciences Ltd. | Add +12.7% | 0.58% | −0.06 |
| ARWR Arrowhead Pharmaceuticals Inc. | Add +5.0% | 2.13% | −0.11 |
| IGMS Igm Biosciences Inc. | Add +8.1% | 0.59% | −0.18 |
| APLS Apellis Pharmaceuticals Inc. | Add +11.5% | 1.44% | −0.55 |
Options Activity Q1 2024 → Q2 2024
| ARWR Arrowhead Pharmaceuticals Inc. | call | Add +66.7% | 1,000,000 | $26.0M |
| XBI SS SPDR S&P Biotech ETF | call | Sold out | 250,000 | $23.7Mbefore exit |
| PYPL PayPal Holdings Inc. | call | Reduce -55.2% | 26,000 | $1.5M |
Calls and puts are listed by the shares they cover; their value is not part of the stock holdings above.
Notes & Other Activity Q1 2024 → Q2 2024
| PERCEPTION CAPITAL CORP III | *W EXP 99/99/999 | New | 126,666 | $4K |
Bonds, preferreds, convertibles and warrants; not part of the stock holdings or percentages above.
All Filings
| Quarter | Positions | 13F Reported Value | Top Holdings |
|---|---|---|---|
| Q2 2026 | 2 | $931.1M | CAVA, LXRX |
| Q1 2026 | 2 | $1.0B | CAVA, LXRX |
| Q4 2025 | 2 | $714.6M | CAVA, LXRX |
| Q3 2025 | 2 | $758.2M | CAVA, LXRX |
| Q2 2025 | 2 | $930.2M | CAVA, LXRX |
| Q1 2025 | 2 | $884.2M | CAVA, LXRX |
| Q4 2024 | 2 | $1.2B | CAVA, LXRX |
| Q3 2024 | 2 | $2.4B | CAVA, LXRX |
| Q2 2024 | 108 | $3.9B | CAVA, LXRX, SRRK, KYMR, MORF |
| Q1 2024Amended | 107 | $3.9B | CAVA, LXRX, SRRK, KYMR, ARWR |