Taysha Gene TherapiesTSHA
13F holders, Q2 2026 (June 30)At the end of Q2 2026, 208 institutions reported holding Taysha Gene Therapies Inc. (TSHA) in their 13F filings, up 17 from Q1 2026. 39 opened new positions and 22 sold out. The largest holders were Avoro Capital Advisors LLC ($162.7M), Ra Capital Management, L.P. ($160.4M) and Goldman Sachs Group Inc. ($154.7M). 4 famous investors held it, including David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Taysha Gene Therapies Inc.
- CUSIP
- 877619106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $111.1M |
| Exits | 22 | $19.0M |
All 13F filers, Q1 2026 → Q2 2026: 45,232,932 shares bought and 13,505,508 shares sold, net +31,727,424 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 208 holders
| Avoro Capital Advisors LLC | 1.46% | Add +10.1% | 23,888,888 | $162.7M |
| Ra Capital Management, L.P. | 1.39% | No change | 23,555,648 | $160.4M |
| Goldman Sachs Group Inc. | 0.02% | Add +1.5% | 22,713,118 | $154.7M |
| BlackRock, Inc. | 0.00% | Add +12.7% | 20,691,927 | $140.9M |
| Vestal Point Capital, LP | 3.09% | Add +7.9% | 19,415,000 | $132.2M |
| Morgan Stanley | 0.01% | Reduce -8.2% | 16,487,479 | $112.3M |
| RTW Investments, LP | 0.79% | Reduce -0.9% | 13,560,258 | $92.3M |
| FMR LLC | 0.00% | Reduce -6.9% | 13,336,413 | $90.8M |
| Vanguard Capital Management LLC | 0.00% | Add +22.0% | 12,478,595 | $85.0M |
| State Street Corp. | 0.00% | Add +1.9% | 11,421,920 | $77.8M |
| Siren, L.L.C. | 1.36% | Add +11.5% | 9,846,579 | $67.1M |
| Octagon Capital Advisors LP | 6.06% | Add +9.4% | 9,693,244 | $66.0M |
| Geode Capital Management, LLC | 0.00% | Add +18.6% | 6,560,394 | $44.7M |
| Polar Capital Holdings Plc | 0.10% | Reduce -9.5% | 5,117,133 | $34.8M |
| MPM Bioimpact LLC | 1.87% | New | 4,500,000 | $30.6M |
| D. E. Shaw & Co. | 0.02% | Reduce -0.7% | 4,398,652 | $30.0M |
| Baker Bros. Advisors LP | 0.14% | No change | 4,004,756 | $27.3M |
| Wellington Management Group LLP | 0.00% | Add +534.7% | 3,975,605 | $27.1M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.04% | Add +34.8% | 3,885,501 | $26.5M |
| GordonMD Global Investments LP | 11.86% | Reduce -1.9% | 723,185 | $24.5M |
| Casdin Capital, LLC | 1.11% | No change | 3,250,000 | $22.1M |
| Vanguard Portfolio Management LLC | 0.00% | Add +55.3% | 3,140,009 | $21.4M |
| ADAR1 Capital Management, LLC | 0.98% | Add +2.0% | 3,040,466 | $20.7M |
| Pictet Asset Management Holding SA | 0.02% | Add +14242.6% | 2,770,701 | $18.9M |
| Aberdeen Group plc | 0.02% | Add +127.9% | 2,327,152 | $15.8M |
| Farallon Capital Management, L.L.C. | 0.09% | New | 2,250,000 | $15.3M |
| Norges Bank | 0.00% | — | 2,233,600 | $15.2M |
| Northern Trust Corp. | 0.00% | Add +22.7% | 2,226,210 | $15.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +21.7% | 2,200,695 | $15.0M |
| Millennium Management | 0.01% | Reduce -35.2% | 2,126,838 | $14.5M |
| Orbimed Advisors LLC | 0.26% | New | 2,000,000 | $13.6M |
| Rice Hall James & Associates, LLC | 0.66% | Add +2.5% | 1,992,229 | $13.6M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +23.9% | 1,896,474 | $12.9M |
| B Group, Inc. | 6.96% | No change | 1,800,556 | $12.3M |
| Affinity Asset Advisors, LLC | 0.59% | Add +75.0% | 1,750,000 | $11.9M |
| Barclays PLC | 0.00% | Reduce -42.0% | 1,630,659 | $11.1M |
| Citadel Advisors | 0.01% | Add +273.4% | 1,535,287 | $10.5M |
| Heights Capital Management, Inc. | 2.40% | New | 1,500,000 | $10.2M |
| Seven Fleet Capital Management LP | 1.64% | Add +140.4% | 1,504,400 | $9.9M |
| Palo Alto Investors LP | 1.31% | No change | 1,391,382 | $9.5M |
| Bank of America Corp. | 0.00% | Reduce -18.1% | 1,372,845 | $9.3M |
| Granahan Investment Management, LLC | 0.32% | Add +47.8% | 1,305,177 | $8.9M |
| Quantum Private Wealth, LLC | 1.42% | Reduce -4.4% | 812,027 | $5.5M |
| First Trust Advisors LP | 0.00% | New | 791,169 | $5.4M |
| JPMorgan Chase & Co. | 0.00% | Add +1.5% | 766,282 | $5.2M |
| Sands Capital Alternatives, LLC | 0.80% | No change | 724,873 | $4.9M |
| Bank of New York Mellon Corp | 0.00% | Add +14.8% | 697,971 | $4.8M |
| BNP Paribas Financial Markets | 0.00% | Add +432.5% | 640,035 | $4.4M |
| Panagora Asset Management Inc. | 0.01% | Add +224.1% | 590,387 | $4.0M |
| UBS Group AG | 0.00% | Add +13.7% | 588,427 | $4.0M |
| Affinity Wealth Management LLC | 0.51% | New | 576,808 | $3.9M |
| Squarepoint Ops LLC | 0.01% | Add +38.8% | 569,269 | $3.9M |
| Acuta Capital Partners, LLC | 2.67% | Add +27.8% | 561,808 | $3.8M |
| Nuveen, LLC | 0.00% | Add +1.2% | 555,693 | $3.8M |
| Adage Capital Partners Gp, L.L.C. | 0.01% | New | 553,000 | $3.8M |
| Diadema Partners LP | 1.35% | New | 522,619 | $3.6M |
| Hennion & Walsh Asset Management, Inc. | 0.10% | Add +32.6% | 519,120 | $3.5M |
| Woodline Partners LP | 0.01% | No change | 513,828 | $3.5M |
| Holocene Advisors, LP | 0.01% | New | 510,000 | $3.5M |
| Ghisallo Capital Management LLC | 0.08% | New | 505,000 | $3.4M |
| Burkehill Global Management, LP | 0.13% | New | 500,000 | $3.4M |
| Polen Capital Management LLC | 0.03% | Add +53.0% | 489,219 | $3.3M |
| Dimensional Fund Advisors LP | 0.00% | Reduce -5.2% | 464,771 | $3.2M |
| Voya Investment Management LLC | 0.00% | Reduce -16.9% | 425,363 | $2.9M |
| Trexquant Investment LP | 0.02% | New | 379,577 | $2.6M |
| Swiss National Bank | 0.00% | Add +37.3% | 369,000 | $2.5M |
| Moore Capital Management, LP | 0.06% | Add +9.0% | 358,374 | $2.4M |
| Wells Fargo & Company | 0.00% | Add +81.8% | 333,314 | $2.3M |
| Jefferies Financial Group Inc. | 0.02% | Reduce -31.4% | 328,800 | $2.2M |
| Citigroup Inc. | 0.00% | Add +437.7% | 306,907 | $2.1M |
| Rhumbline Advisers | 0.00% | Add +16.0% | 299,975 | $2.0M |
| Alps Advisors Inc. | 0.01% | Add +30.3% | 290,543 | $2.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +2.6% | 272,600 | $1.9M |
| Invesco Ltd. | 0.00% | Reduce -28.2% | 264,379 | $1.8M |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -4.4% | 262,896 | $1.8M |
| Qube Research & Technologies Ltd | 0.00% | New | 259,605 | $1.8M |
| Sphera Funds Management LTD. | 0.24% | New | 250,000 | $1.7M |
| Deutsche Bank AG | 0.00% | Add +33.9% | 243,379 | $1.7M |
| Two Sigma Investments, LP | 0.00% | Reduce -68.4% | 234,716 | $1.6M |
| Jane Street Group, LLC | 0.00% | New | 228,355 | $1.6M |
| SG Americas Securities, LLC | 0.00% | Reduce -90.7% | 202,260 | $1.4M |
| Monashee Investment Management LLC | 3.29% | New | 200,000 | $1.4M |
| T. Rowe Price Associates Inc. | 0.00% | Add +25.5% | 199,494 | $1.4M |
| Privium Fund Management B.V. | 0.25% | Add +9.3% | 198,900 | $1.4M |
| Victory Capital Management Inc. | 0.00% | Add +0.9% | 197,578 | $1.3M |
| Chicago Partners Investment Group LLC | 0.03% | Add +30.2% | 222,347 | $1.3M |
| Balyasny Asset Management L.P. | 0.00% | Add +128.1% | 189,332 | $1.3M |
| State of Wisconsin Investment Board | 0.00% | Reduce -32.8% | 177,089 | $1.2M |
| California State Teachers Retirement System | 0.00% | Add +23.7% | 169,374 | $1.2M |
| Raymond James Financial Inc. | 0.00% | Add +653.7% | 166,042 | $1.1M |
| Alliancebernstein L.P. | 0.00% | Add +30.9% | 247,680 | $1.1M |
| Wexford Capital LP | 0.15% | No change | 160,654 | $1.1M |
| Rafferty Asset Management, LLC | 0.00% | Reduce -48.4% | 154,706 | $1.1M |
| Palumbo Wealth Management LLC | 0.21% | Add +1.7% | 149,173 | $1.0M |
| MetLife Investment Management, LLC | 0.00% | Add +17.3% | 140,846 | $959K |
| Vanguard Global Advisers, LLC | 0.00% | Add +14.7% | 133,821 | $911K |
| Persistent Asset Partners Ltd | 0.29% | New | 133,411 | $909K |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | Add +46.6% | 132,614 | $903K |
| AQR Capital Management | 0.00% | Reduce -27.4% | 128,764 | $877K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.5% | 127,915 | $870K |
"% of holder's portfolio" is TSHA's weight in each manager's 13F, not the share of Taysha Gene Therapies Inc. the manager owns.