Knott David M Jr

In its 13F for Q3 2024 (holdings as of September 30, 2024, filed November 13, 2024), Knott David M Jr reported 92 stock positions worth $284.6 million. Its top holding was Calumet (CLMT) at 27.1% of the portfolio, followed by Apollo Global Management (APO, 9.9%) and Alphabet Class C (GOOG, 6.7%). Compared with Q2 2024, it opened 8 new positions, sold out of 15, added to 8 and reduced 23. The biggest buy was a new position in Biomarin Pharmaceutical (BMRN) and the biggest sale an exit from Ligand Pharmaceuticals (LGND).

Most Recent 13F
Q2 2026
Location
SYOSSET, NY
CIK
0001892770
Portfolio Value
$284.6M (Q3 2024)
SEC Filing
0001104659-24-117555 ↗ filed Nov 13, 2024

Holdings Value

0$100.0M$200.0M$300.0M Q1 2024: $282.8M Q1 2024 Q2 2024: $250.6M Q2 2024 Q3 2024: $284.6M $284.6M Q3 2024 Q4 2024: $276.5M Q4 2024 Q1 2025: $212.0M Q1 2025 Q2 2025: $220.6M Q2 2025 Q3 2025: $238.7M Q3 2025 Q4 2025: $215.9M Q4 2025 Q1 2026: $168.0M Q1 2026 Q2 2026: $189.2M Q2 2026

Holdings 92 stocks · $284.6M
CLMT Calumet Inc. 27.08% 4,325,000 $77.1M No change
APO Apollo Global Management Inc. 9.88% 225,000 $28.1M No change
GOOG Alphabet Inc. Class C 6.71% 112,220 $19.1M No change
AB Alliancebernstein Holding LP 5.88% 48,000 $16.7M Reduce -2.0%
CLOZ Eldridge BBB-B Clo ETF 5.13% 542,868 $14.6M No change
DCGO Docgo Inc. 3.58% 3,070,850 $10.2M No change
ABBV Abbvie Inc. 3.50% 5,037 $9.9M No change
PFE Pfizer Inc. 2.28% 224,537 $6.5M Reduce -9.7%
AAPL Apple Inc. 2.04% 2,494 $5.8M No change
MFCSF Medical Facilities Corp. 1.87% 534,207 $5.3M No change
VRNA Verona Pharma Ltd. 1.82% 180,000 $5.2M Reduce -11.3%
OABI Omniab Inc. 1.71% 1,148,505 $4.9M Add +2.7%
ICLO Invesco Aaa Clo F/R Note ETF 1.70% 188,887 $4.8M Reduce -20.6%
ARDX Ardelyx Inc. 1.65% 682,867 $4.7M Reduce -11.6%
JPM JPMorgan Chase & Co. 1.55% 20,985 $4.4M No change
AVDL Avadel Pharmaceuticals plc 1.53% 332,000 $4.4M Reduce -0.3%
JAAA Janus Henderson Aaa Clo ETF 1.52% 84,829 $4.3M Add +58.9%
CPRX Catalyst Pharmaceuticals Inc. 1.48% 212,000 $4.2M No change
TVTX Travere Therapeutics Inc. 1.27% 258,231 $3.6M Reduce -2.9%
INZY Inozyme Pharma Inc. 1.04% 564,549 $3.0M No change
BCRX Biocryst Pharmaceuticals Inc. 1.02% 382,000 $2.9M Add +21.5%
XERS Xeris Biopharma Holdings Inc. 1.00% 1,000,000 $2.9M Add +21.9%
GSK GSK PLC-Spon ADR 0.93% 65,000 $2.7M No change
IMVT Immunovant Inc. 0.92% 92,000 $2.6M Add +0.6%
VKTX Viking Therapeutics Inc. 0.87% 39,036 $2.5M Reduce -48.7%
CSX CSX Corp. 0.85% 70,000 $2.4M No change
ESGR Enstar Group Ltd. 0.85% 7,500 $2.4M No change
BMRN Biomarin Pharmaceutical Inc. 0.84% 34,000 $2.4M New
PTGX Protagonist Therapeutics Inc. 0.83% 52,368 $2.4M No change
SNDX Syndax Pharmaceuticals Inc. 0.83% 122,144 $2.4M Add +17.6%
DMRC Digimarc Corp. 0.79% 83,557 $2.2M No change
MREO Mereo Biopharma Group PL-ADR 0.48% 331,000 $1.4M Add +40.3%
RHP Ryman Hospitality Properties 0.45% 12,000 $1.3M No change
XBI SS SPDR S&P Biotech ETF 0.35% 10,000 $988K Reduce -28.6%
EOLS Evolus Inc. 0.33% 57,570 $933K Reduce -47.0%
VRTX Vertex Pharmaceuticals Inc. 0.33% 2,000 $930K Reduce -33.3%
DD Dupont DE Nemours Inc. 0.31% 9,930 $885K No change
KMB Kimberly-Clark Corp. 0.30% 6,000 $854K No change
IRWD Ironwood Pharmaceuticals Inc. 0.30% 207,033 $853K Reduce -44.0%
XENE Xenon Pharmaceuticals Inc. 0.29% 20,866 $821K No change
LXRX Lexicon Pharmaceuticals Inc. 0.28% 500,000 $785K New
ROIV Roivant Sciences Ltd. 0.25% 61,583 $711K Reduce -2.3%
MSFT Microsoft Corp. 0.24% 1,600 $688K No change
CTVA Corteva Inc. 0.24% 11,563 $680K No change
MDLZ Mondelez International Inc. Class A 0.23% 9,000 $663K Reduce -35.7%
ZIMV Zimvie Inc. 0.20% 35,750 $567K New
AMZN Amazon.com Inc. 0.20% 300 $559K No change
CNQ Canadian Natural Resources 0.20% 16,800 $558K No change
XOMA Xoma Royalty Corporation 0.18% 19,722 $522K No change
CLOX Eldridge Aaa Clo ETF 0.18% 19,572 $500K No change
GOOGL Alphabet Inc. Class A 0.17% 300 $497K No change
IBM Intl Business Machines Corp. filed as INTERNATIONAL BUSINESS MACHS 0.17% 2,142 $474K No change
EDIT Editas Medicine Inc. 0.16% 135,853 $463K Reduce -23.3%
KURA Kura Oncology Inc. 0.13% 19,000 $371K Add +90.0%
LLY Eli Lilly & Co. 0.09% 300 $266K No change
ATYR Atyr Pharma Inc. 0.07% 107,174 $189K New
ARCH Arch Resources Inc. 0.07% 1,110 $187K Reduce -9.7%
ADBE Adobe Inc. 0.06% 35 $181K No change
LEGH Legacy Housing Corp. 0.06% 6,500 $178K No change
CYPH Cypherpunk Technologies Inc. filed as LEAP THERAPEUTICS INC 0.06% 65,328 $168K Reduce -42.9%
RVNC Revance Therapeutics Inc. 0.06% 31,355 $163K New
NVDA Nvidia Corp. 0.05% 1,280 $155K No change
JNJ Johnson & Johnson 0.05% 922 $149K No change
KO The Coca-Cola Co. 0.05% 2,000 $144K Reduce -73.7%
AVGO Broadcom Inc. 0.04% 710 $122K No change
XFOR X4 Pharmaceuticals Inc. 0.04% 154,071 $103K Reduce -14.9%
EBC Eastern Bankshares Inc. 0.03% 5,000 $82K No change
IWP iShares Russell Mid-Cap Grow 0.03% 695 $82K No change
TTE Totalenergies SE -Spon ADR 0.03% 1,200 $78K Reduce -25.0%
DOW Dow Inc. 0.02% 1,206 $66K Reduce -89.2%
FSBW FS Bancorp Inc. 0.02% 1,460 $65K Reduce -66.7%
URI United Rentals Inc. 0.02% 78 $63K No change
OXY Occidental Petroleum Corp. 0.02% 1,249 $58K No change
FSK FS KKR Capital Corp. 0.02% 2,875 $57K No change
INTL GAME TECHNOLOGY filed as International Game Technology PLC 0.02% 2,500 $53K Reduce -66.7%
KVUE Kenvue Inc. 0.02% 2,235 $52K No change
PWR Quanta Services Inc. 0.02% 176 $52K No change
SSB Southstate Bank Corp. 0.02% 534 $52K No change
DHR Danaher Corp. 0.02% 180 $50K No change
UNH Unitedhealth Group Inc. 0.01% 57 $33K No change
LIN Linde PLC 0.01% 70 $33K New
BX Blackstone Inc. 0.01% 210 $32K No change
HD Home Depot Inc. 0.01% 80 $32K No change
CMG Chipotle Mexican Grill Inc. 0.01% 500 $29K No change
GE General Electric filed as GE AEROSPACE 0.01% 150 $28K New
TMO Thermo Fisher Scientific Inc. 0.01% 45 $28K No change
CRM Salesforce Inc. 0.01% 77 $21K No change
MGTX Meiragtx Holdings PLC 0.01% 4,703 $20K New
KD Kyndryl Holdings Inc. 0.00% 428 $10K No change
STWD Starwood Property Trust Inc. 0.00% 400 $8K No change
GEHC GE Healthcare Technology 0.00% 50 $5K No change
WAB Wabtec Corp. 0.00% 6 $1K No change

Portfolio Sells Q2 2024 → Q3 2024
LGND Ligand Pharmaceuticals Sold out 0.00% −2.86
LKNCY Luckin Coffee Inc. - ADR Sold out 0.00% −0.84
VKTX Viking Therapeutics Inc. Reduce -48.7% 0.87% −0.74
ICLO Invesco Aaa Clo F/R Note ETF Reduce -20.6% 1.70% −0.73
IRWD Ironwood Pharmaceuticals Inc. Reduce -44.0% 0.30% −0.66
Janus Henderson AAA CLO ETF Sold out 0.00% −0.64
ARDX Ardelyx Inc. Reduce -11.6% 1.65% −0.63
PFE Pfizer Inc. Reduce -9.7% 2.28% −0.49
AVDL Avadel Pharmaceuticals plc Reduce -0.3% 1.53% −0.34
VRTX Vertex Pharmaceuticals Inc. Reduce -33.3% 0.33% −0.23
DOW Dow Inc. Reduce -89.2% 0.02% −0.21
BBIO Bridgebio Pharma Inc. Sold out 0.00% −0.21
XBI SS SPDR S&P Biotech ETF Reduce -28.6% 0.35% −0.17
EDIT Editas Medicine Inc. Reduce -23.3% 0.16% −0.17
CRNX Crinetics Pharmaceuticals Inc. Sold out 0.00% −0.15
EOLS Evolus Inc. Reduce -47.0% 0.33% −0.14
KO The Coca-Cola Co. Reduce -73.7% 0.05% −0.14
MDLZ Mondelez International Inc. Class A Reduce -35.7% 0.23% −0.13
CAG Conagra Brands Inc. Sold out 0.00% −0.11
FNB FNB Corp. Sold out 0.00% −0.05
INTL GAME TECHNOLOGY Reduce -66.7% 0.02% −0.04
FSBW FS Bancorp Inc. Reduce -66.7% 0.02% −0.04
CYPH Cypherpunk Technologies Inc. Reduce -42.9% 0.06% −0.03
ROIV Roivant Sciences Ltd. Reduce -2.3% 0.25% −0.02
TTE Totalenergies SE -Spon ADR Reduce -25.0% 0.03% −0.02
HRGG Heritage Nola Bancshares Inc. Sold out 0.00% −0.01
LIN Linde PLC Sold out 0.00% −0.01
GE General Electric Co.-Wi Sold out 0.00% −0.01
VLY Valley National Bancorp Sold out 0.00% −0.01
OVID Ovid Therapeutics Inc. Sold out 0.00% −0.01
XFOR X4 Pharmaceuticals Inc. Reduce -14.9% 0.04% −0.01
KHC The Kraft Heinz Co. Sold out 0.00% −0.00
GE VERNOVA INC Sold out 0.00% −0.00
CC The Chemours Co. Sold out 0.00% −0.00
ARCH Arch Resources Inc. Reduce -9.7% 0.07% +0.05
TVTX Travere Therapeutics Inc. Reduce -2.9% 1.27% +0.40
VRNA Verona Pharma Ltd. Reduce -11.3% 1.82% +0.65
AB Alliancebernstein Holding LP Reduce -2.0% 5.88% +5.22

Portfolio Buys Q2 2024 → Q3 2024
BMRN Biomarin Pharmaceutical Inc. New 0.84% +0.84
JAAA Janus Henderson Aaa Clo ETF Add +58.9% 1.52% +0.43
LXRX Lexicon Pharmaceuticals Inc. New 0.28% +0.28
XERS Xeris Biopharma Holdings Inc. Add +21.9% 1.00% +0.27
BCRX Biocryst Pharmaceuticals Inc. Add +21.5% 1.02% +0.25
ZIMV Zimvie Inc. New 0.20% +0.20
MREO Mereo Biopharma Group PL-ADR Add +40.3% 0.48% +0.14
ATYR Atyr Pharma Inc. New 0.07% +0.07
RVNC Revance Therapeutics Inc. New 0.06% +0.06
KURA Kura Oncology Inc. Add +90.0% 0.13% +0.05
OABI Omniab Inc. Add +2.7% 1.71% +0.03
LIN Linde PLC New 0.01% +0.01
GE General Electric New 0.01% +0.01
MGTX Meiragtx Holdings PLC New 0.01% +0.01
SNDX Syndax Pharmaceuticals Inc. Add +17.6% 0.83% −0.02
IMVT Immunovant Inc. Add +0.6% 0.92% −0.04

All Filings

QuarterPositions13F Reported ValueTop Holdings
Q2 2026 83$189.2MGOOG, APO, SNDX, XERS, TVTX
Q1 2026 85$168.0MGOOG, APO, SNDX, BBIO, PTGX
Q4 2025 87$215.9MCLMT, APO, GOOG, SNDX, XERS
Q3 2025 87$238.7MCLMT, APO, GOOG, JAAA, XERS
Q2 2025 85$220.6MCLMT, APO, JAAA, GOOG, JPM
Q1 2025 84$212.0MCLMT, APO, JAAA, GOOG, DCGO
Q4 2024 89$276.5MCLMT, APO, JAAA, GOOG, DCGO
Q3 2024 92$284.6MCLMT, APO, GOOG, AB, CLOZ
Q2 2024 99$250.6MCLMT, APO, GOOG, CLOZ, DCGO
Q1 2024 106$282.8MCLMT, APO, CLOZ, GOOG, FTAI