Agios PharmaceuticalsAGIO
13F holders, Q3 2025 (September 30)221holders +6
39new positions
34sold out
6famous investors
$40.10avg. 13F price*
At the end of Q3 2025, 221 institutions reported holding Agios Pharmaceuticals Inc. (AGIO) in their 13F filings, up 6 from Q2 2025. 39 opened new positions and 34 sold out. The largest holders were Farallon Capital Management, L.L.C. ($232.1M), Vanguard Group Inc. ($225.0M) and BlackRock, Inc. ($182.5M). 6 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Ken Fisher (0.0% of Fisher Asset Management's portfolio).
- Company
- Agios Pharmaceuticals Inc.
- CUSIP
- 00847X104
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $78.2M |
| Exits | 34 | $80.7M |
All 13F filers, Q2 2025 → Q3 2025: 8,822,197 shares bought and 7,182,936 shares sold, net +1,639,261 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 221 holders
| Farallon Capital Management, L.L.C. | 1.31% | Add +0.2% | 5,781,066 | $232.1M |
| Vanguard Group Inc. | 0.00% | Reduce -1.4% | 5,604,876 | $225.0M |
| BlackRock, Inc. | 0.00% | Reduce -6.0% | 4,545,738 | $182.5M |
| Bellevue Group AG | 3.10% | Add +3.5% | 3,714,736 | $149.1M |
| Erste Asset Management GmbH | 1.05% | Add +18.8% | 2,764,900 | $108.6M |
| Paradigm Biocapital Advisors LP | 3.18% | Add +134.0% | 2,673,555 | $107.3M |
| Wellington Management Group LLP | 0.02% | Add +485.5% | 2,471,416 | $99.2M |
| Commodore Capital LP | 4.58% | Add +0.6% | 2,338,287 | $93.9M |
| State Street Corp. | 0.00% | Add +16.0% | 2,262,712 | $90.8M |
| Macquarie Group Ltd. | 0.09% | Add +3.0% | 1,958,101 | $78.6M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -27.1% | 1,656,938 | $66.5M |
| TCG Crossover Management, LLC | 2.82% | Add +105.2% | 1,430,041 | $57.4M |
| Geode Capital Management, LLC | 0.00% | Add +0.8% | 1,416,315 | $56.9M |
| Frazier Life Sciences Management, L.P. | 1.54% | No change | 1,279,754 | $51.4M |
| Caligan Partners LP | 6.30% | Add +5.6% | 1,131,205 | $45.4M |
| Bank of America Corp. | 0.00% | Add +0.9% | 1,130,000 | $45.4M |
| Dimensional Fund Advisors LP | 0.01% | Reduce -7.7% | 1,021,201 | $41.0M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.10% | Reduce -2.9% | 987,339 | $39.6M |
| Rock Springs Capital Management LP | 2.26% | Reduce -3.1% | 958,542 | $38.5M |
| Deutsche Bank AG | 0.01% | Add +0.6% | 926,734 | $37.2M |
| Fisher Asset Management | 0.01% | Reduce -0.8% | 870,145 | $34.9M |
| GW&K Investment Management, LLC | 0.30% | Reduce -1.8% | 852,942 | $34.2M |
| Goldman Sachs Group Inc. | 0.00% | Add +24.2% | 804,766 | $32.3M |
| Adage Capital Partners Gp, L.L.C. | 0.05% | Add +1.1% | 800,000 | $32.1M |
| Armistice Capital, LLC | 0.96% | Reduce -34.6% | 764,000 | $30.7M |
| ArrowMark Colorado Holdings LLC | 0.51% | Add +3.2% | 679,922 | $27.3M |
| SCS Capital Management LLC | 0.26% | Reduce -0.9% | 598,765 | $24.0M |
| Northern Trust Corp. | 0.00% | Reduce -0.3% | 555,410 | $22.3M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.07% | Add +4.9% | 530,098 | $21.3M |
| Balyasny Asset Management L.P. | 0.04% | New | 495,491 | $19.9M |
| Boothbay Fund Management, LLC | 0.53% | Add +10.8% | 495,341 | $19.9M |
| Citadel Advisors | 0.02% | Reduce -54.5% | 491,982 | $19.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.3% | 482,186 | $19.4M |
| Morgan Stanley | 0.00% | Add +42.8% | 416,998 | $16.7M |
| Artisan Partners Limited Partnership | 0.02% | Add +3.3% | 402,943 | $16.2M |
| Jane Street Group, LLC | 0.02% | Add +1079.8% | 395,120 | $15.9M |
| D. E. Shaw & Co. | 0.01% | Reduce -38.3% | 367,749 | $14.8M |
| Legal & General Group Plc | 0.00% | Add +402.2% | 322,934 | $13.0M |
| Bank of New York Mellon Corp | 0.00% | Add +1.3% | 270,096 | $10.8M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -7.7% | 272,161 | $10.7M |
| Palo Alto Investors LP | 1.97% | Reduce -1.2% | 265,497 | $10.7M |
| SummitTX Capital, L.P. | 0.44% | New | 262,977 | $10.6M |
| Eagle Health Investments LP | 2.59% | Reduce -25.6% | 246,230 | $9.9M |
| UBS Group AG | 0.00% | Add +104.3% | 242,813 | $9.7M |
| Marshall Wace, LLP | 0.01% | Reduce -66.9% | 226,824 | $9.1M |
| Barclays PLC | 0.00% | Add +19.6% | 216,040 | $8.7M |
| HighVista Strategies LLC | 1.92% | Add +178.5% | 195,298 | $7.8M |
| Baker Bros. Advisors LP | 0.06% | No change | 189,866 | $7.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -82.2% | 183,100 | $7.3M |
| AXA Investment Managers S.A. | 0.02% | — | 177,675 | $7.1M |
| Peregrine Capital Management LLC | 0.20% | New | 162,905 | $6.5M |
| Allianz Asset Management GmbH | 0.01% | Add +5.6% | 146,643 | $5.9M |
| Alyeska Investment Group, L.P. | 0.02% | New | 146,514 | $5.9M |
| American Century Companies Inc. | 0.00% | Add +13.7% | 145,121 | $5.8M |
| Patient Square Capital LP | 1.44% | Reduce -4.2% | 133,827 | $5.4M |
| TD Asset Management Inc | 0.00% | Reduce -23.7% | 128,294 | $5.1M |
| Vestal Point Capital, LP | 0.23% | New | 127,000 | $5.1M |
| Ikarian Capital, LLC | 1.03% | New | 126,979 | $5.1M |
| Invesco Ltd. | 0.00% | Add +12.8% | 126,976 | $5.1M |
| Hudson Bay Capital Management LP | 0.03% | Reduce -5.8% | 122,500 | $4.9M |
| Nuveen, LLC | 0.00% | No change | 119,580 | $4.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -50.8% | 106,875 | $4.3M |
| Swiss National Bank | 0.00% | Reduce -2.6% | 106,660 | $4.3M |
| Parkman Healthcare Partners LLC | 0.44% | New | 100,380 | $4.0M |
| Nantahala Capital Management, LLC | 0.25% | New | 100,000 | $4.0M |
| Prudential Financial Inc. | 0.00% | Reduce -38.0% | 98,239 | $3.9M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -27.3% | 96,012 | $3.9M |
| AQR Capital Management | 0.00% | Reduce -5.4% | 91,635 | $3.6M |
| Jump Financial, LLC | 0.05% | New | 87,900 | $3.5M |
| Rhumbline Advisers | 0.00% | Reduce -2.4% | 87,702 | $3.5M |
| First Trust Advisors LP | 0.00% | Add +104.3% | 74,429 | $3.0M |
| Woodline Partners LP | 0.01% | Reduce -68.3% | 73,996 | $3.0M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +28.8% | 71,213 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +38.1% | 68,220 | $2.7M |
| Assenagon Asset Management S.A. | 0.00% | New | 67,153 | $2.7M |
| Alliancebernstein L.P. | 0.00% | Add +0.1% | 61,503 | $2.5M |
| California State Teachers Retirement System | 0.00% | Add +28.6% | 61,296 | $2.5M |
| Two Sigma Investments, LP | 0.00% | New | 59,629 | $2.4M |
| Moore Capital Management, LP | 0.04% | Reduce -31.3% | 55,000 | $2.2M |
| New York State Common Retirement Fund | 0.00% | Add +27.4% | 49,790 | $2.0M |
| Phocas Financial Corp. | 0.24% | New | 46,608 | $1.9M |
| Wells Fargo & Company | 0.00% | Add +18.7% | 44,754 | $1.8M |
| Citigroup Inc. | 0.00% | Reduce -22.8% | 43,620 | $1.8M |
| VIRGINIA RETIREMENT SYSTEMS ET Al | 0.01% | Reduce -17.3% | 41,061 | $1.6M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 40,000 | $1.6M |
| Ameriprise Financial Inc. | 0.00% | Reduce -26.5% | 38,428 | $1.5M |
| ADAR1 Capital Management, LLC | 0.15% | Add +3.1% | 37,000 | $1.5M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -7.5% | 36,592 | $1.5M |
| Algert Global LLC | 0.02% | Reduce -59.7% | 35,770 | $1.4M |
| State of Wisconsin Investment Board | 0.00% | Reduce -39.8% | 35,573 | $1.4M |
| Edgewood Management LLC | 0.01% | No change | 35,000 | $1.4M |
| Harbor Capital Advisors, Inc. | 0.11% | Reduce -5.9% | 34,835 | $1.4M |
| MetLife Investment Management, LLC | 0.01% | No change | 34,032 | $1.4M |
| Sei Investments Co. | 0.00% | Add +212.8% | 32,300 | $1.3M |
| Victory Capital Management Inc. | 0.00% | Add +2.8% | 30,232 | $1.2M |
| SG Americas Securities, LLC | 0.00% | New | 27,650 | $1.1M |
| Alps Advisors Inc. | 0.01% | Reduce -11.9% | 27,554 | $1.1M |
| Hennion & Walsh Asset Management, Inc. | 0.04% | Add +70.0% | 25,501 | $1.0M |
| Oak Ridge Investments LLC | 0.07% | Reduce -31.9% | 25,385 | $1.0M |
| Kennedy Capital Management LLC | 0.02% | Reduce -32.9% | 24,641 | $989K |
| Janus Henderson Group PLC | 0.00% | No change | 23,797 | $955K |
| Intech Investment Management LLC | 0.01% | Add +3.4% | 23,578 | $946K |
| FMR LLC | 0.00% | Add +11.4% | 20,712 | $831K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +24.9% | 20,476 | $822K |
| CANADA LIFE ASSURANCE Co | 0.00% | Add +3.4% | 20,325 | $796K |
| Handelsbanken Fonder AB | 0.00% | No change | 19,323 | $776K |
| Royal Bank of Canada | 0.00% | Reduce -24.3% | 17,527 | $705K |
| Caption Management, LLC | 0.04% | Add +2.9% | 17,494 | $702K |
| WINTON GROUP Ltd | 0.02% | New | 16,400 | $658K |
| Arizona State Retirement System | 0.00% | Reduce -2.5% | 16,255 | $652K |
| Rockefeller Capital Management L.P. | 0.00% | New | 16,038 | $644K |
| Guggenheim Capital LLC | 0.00% | Reduce -11.2% | 15,902 | $638K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 15,847 | $636K |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Add +21.0% | 15,633 | $628K |
| Freestone Grove Partners LP | 0.00% | New | 15,424 | $619K |
| Profund Advisors LLC | 0.02% | Add +39.2% | 15,109 | $606K |
| Tidal Investments LLC | 0.00% | Reduce -4.2% | 14,914 | $599K |
| BNP Paribas Financial Markets | 0.00% | Add +23.4% | 14,698 | $590K |
| Two Sigma Advisers, LP | 0.00% | New | 13,600 | $546K |
| Teacher Retirement System of Texas | 0.00% | Reduce -12.5% | 13,484 | $541K |
| Atria Investments, Inc | 0.01% | Reduce -0.7% | 13,386 | $537K |
| Henshaw Capital LLC | 0.02% | Reduce -5.8% | 13,227 | $531K |
| Creative Planning | 0.00% | Add +2.2% | 13,119 | $527K |
| Virtus Investment Advisers, LLC | 0.15% | No change | 12,881 | $517K |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -49.5% | 12,620 | $507K |
| Brevan Howard Capital Management LP | 0.01% | Reduce -58.6% | 12,071 | $485K |
| Savvy Advisors, Inc. | 0.02% | Reduce -44.9% | 11,993 | $481K |
| KLP Kapitalforvaltning As | 0.00% | No change | 11,800 | $474K |
| ProShare Advisors LLC | 0.00% | Reduce -14.7% | 11,728 | $471K |
| Inspire Investing, LLC | 0.04% | Reduce -2.8% | 11,395 | $457K |
| Gallagher Fiduciary Advisors, LLC | 0.02% | Reduce -1.9% | 11,260 | $452K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 11,200 | $450K |
| China Universal Asset Management Co., Ltd. | 0.03% | Reduce -12.4% | 10,184 | $409K |
| Voya Investment Management LLC | 0.00% | Reduce -34.2% | 10,134 | $407K |
| Cinctive Capital Management LP | 0.02% | New | 10,099 | $405K |
| Envestnet Asset Management Inc. | 0.00% | Reduce -6.7% | 9,423 | $378K |
| Commerce Bank | 0.00% | Reduce -4.6% | 9,159 | $368K |
| Y-Intercept (Hong Kong) Ltd | 0.01% | New | 7,932 | $318K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -26.2% | 6,856 | $275K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 6,796 | $273K |
| Voleon Capital Management LP | 0.01% | New | 6,682 | $268K |
| Point72 Asset Management | 0.00% | New | 6,507 | $261K |
| Cerity Partners LLC | 0.00% | Reduce -5.2% | 6,439 | $258K |
| Cubist Systematic Strategies, LLC | 0.00% | New | 6,264 | $251K |
| CIBC Bancorp USA Inc. | 0.00% | — | 6,021 | $242K |
| Fiduciary Trust Co | 0.00% | New | 5,454 | $219K |
| AlphaQuest LLC | 0.01% | Add +708.8% | 5,411 | $217K |
| Northcape Wealth Management, LLC | 0.06% | New | 5,240 | $210K |
| Millennium Management | 0.00% | Reduce -98.3% | 5,049 | $203K |
| Quarry LP | 0.05% | New | 5,000 | $201K |
| North Star Asset Management Inc. | 0.01% | New | 5,000 | $201K |
| Cwm, LLC | 0.00% | Reduce -9.4% | 4,791 | $192K |
| Ameritas Investment Partners, Inc. | 0.01% | Reduce -20.2% | 4,719 | $189K |
| PNC Financial Services Group, Inc. | 0.00% | Add +3.0% | 4,554 | $183K |
| Sterling Capital Management LLC | 0.00% | Add +158.2% | 3,911 | $157K |
| Torno Capital, LLC | 0.01% | New | 2,500 | $100K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.4% | 2,246 | $90K |
| Quantbot Technologies LP | 0.00% | New | 1,976 | $79K |
| Amalgamated Bank | 0.00% | No change | 1,957 | $79K |
| KBC Group NV | 0.00% | No change | 1,751 | $70K |
| BIT Capital GmbH | 0.00% | Reduce -29.6% | 1,571 | $63K |
| Tower Research Capital LLC (TRC) | 0.00% | Reduce -78.9% | 1,357 | $54K |
| NewEdge Advisors, LLC | 0.00% | No change | 1,273 | $51K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -14.4% | 1,250 | $50K |
| First Horizon Corp. | 0.00% | — | 1,124 | $45K |
| Assetmark, Inc. | 0.00% | No change | 955 | $38K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 780 | $31K |
| Arax Advisory Partners | 0.00% | Add +5300.0% | 702 | $28K |
| US Bancorp \de | 0.00% | No change | 569 | $23K |
| Signaturefd, LLC | 0.00% | No change | 513 | $21K |
| Smartleaf Asset Management LLC | 0.00% | Add +138.3% | 398 | $16K |
| Comerica Bank | 0.00% | Add +6.0% | 374 | $15K |
| Hurley Capital, LLC | 0.01% | No change | 366 | $15K |
| Aspect Partners, LLC | 0.01% | No change | 361 | $14K |
| Advisory Services Network, LLC | 0.00% | New | 350 | $14K |
| Osaic Holdings, Inc. | 0.00% | Reduce -3.2% | 336 | $13K |
| Versant Capital Management, Inc | 0.00% | No change | 316 | $13K |
| Optiver Holding B.V. | 0.00% | Add +1.6% | 310 | $12K |
| Bell Investment Advisors, Inc | 0.00% | No change | 298 | $12K |
| Clearstead Advisors, LLC | 0.00% | No change | 291 | $12K |
| Lanark Financial, Inc. | 0.00% | Reduce -30.1% | 241 | $10K |
| Spire Wealth Management | 0.00% | No change | 230 | $9K |
| GAMMA Investing LLC | 0.00% | Add +12.6% | 206 | $8K |
| Concord Wealth Partners | 0.00% | No change | 200 | $8K |
| Hillsdale Investment Management Inc. | 0.00% | No change | 200 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 204 | $8K |
| Bessemer Group Inc. | 0.00% | Add +69.1% | 186 | $7K |
| Farther Finance Advisors, LLC | 0.00% | Add +6.6% | 161 | $6K |
| Essential Partners LLC | 0.00% | No change | 115 | $5K |
| Root Financial Partners, LLC | 0.00% | New | 106 | $4K |
| Mather Group, Llc. | 0.00% | New | 95 | $4K |
| Private Wealth Management Group, LLC | 0.00% | No change | 84 | $3K |
| Rothschild Investment LLC | 0.00% | Reduce -16.7% | 75 | $3K |
| Covestor Ltd | 0.00% | Add +2033.3% | 64 | $3K |
| Larson Financial Group LLC | 0.00% | New | 74 | $3K |
| JPL Wealth Management, LLC | 0.00% | New | 70 | $3K |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 62 | $2K |
| Federated Hermes, Inc. | 0.00% | Reduce -91.1% | 53 | $2K |
| Halbert Hargrove Global Advisors, LLC | 0.00% | New | 47 | $2K |
| Parkside Financial Bank & Trust | 0.00% | No change | 45 | $2K |
| Raffa Wealth Management, LLC | 0.00% | No change | 32 | $1K |
| Fifth Third Bancorp | 0.00% | New | 30 | $1K |
| MAI Capital Management | 0.00% | Reduce -26.5% | 25 | $1K |
| Allworth Financial LP | 0.00% | Add +13.3% | 17 | $683 |
| JFS Wealth Advisors, LLC | 0.00% | No change | 16 | $643 |
| Quadrant Capital Group LLC | 0.00% | New | 16 | $643 |
| Parallel Advisors, LLC | 0.00% | No change | 12 | $482 |
| True Wealth Design, LLC | 0.00% | No change | 9 | $362 |
| Steward Partners Investment Advisory, LLC | 0.00% | No change | 9 | $361 |
| IFP Advisors, Inc | 0.00% | Add +0.0% | 6 | $241 |
| Wealthspire Advisors, LLC | 0.00% | New | 6 | $241 |
| Fortitude Family Office, LLC | 0.00% | No change | 5 | $201 |
| SBI Securities Co., Ltd. | 0.00% | Add +33.3% | 4 | $161 |
| Bay Harbor Wealth Management, LLC | 0.00% | Add +50.0% | 3 | $120 |
| HFM Investment Advisors, LLC | 0.00% | Add +200.0% | 3 | $120 |
| SJS Investment Consulting Inc. | 0.00% | Add +100.0% | 2 | $81 |
| Rialto Wealth Management, LLC | 0.00% | No change | 2 | $81 |
| Jones Financial Companies LLLP | 0.00% | No change | 1 | $39 |
| DiNuzzo Private Wealth, Inc. | 0.00% | No change | 1 | $38 |
| Hemington Wealth Management | 0.00% | Add +150.0% | 15 | $0 |
| Cloud Capital Management, LLC | 0.00% | New | 1 | $0 |
"% of holder's portfolio" is AGIO's weight in each manager's 13F, not the share of Agios Pharmaceuticals Inc. the manager owns.