Apellis PharmaceuticalsAPLS
13F holders, Q1 2025 (March 31)255holders −5
47new positions
51sold out
5famous investors
$21.89avg. 13F price*
At the end of Q1 2025, 255 institutions reported holding Apellis Pharmaceuticals Inc. (APLS) in their 13F filings, down 5 from Q4 2024. 47 opened new positions and 51 sold out. The largest holders were Wellington Management Group LLP ($269.1M), Avoro Capital Advisors LLC ($267.3M) and EcoR1 Capital, LLC ($260.2M). 5 famous investors held it, including Cliff Asness (0.1% of AQR Capital Management's portfolio), Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Apellis Pharmaceuticals Inc.
- CUSIP
- 03753U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2024 → Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 47 | $75.5M |
| Exits | 51 | $176.9M |
All 13F filers, Q4 2024 → Q1 2025: 16,142,389 shares bought and 14,889,447 shares sold, net +1,252,942 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 255 holders
| Wellington Management Group LLP | 0.05% | Add +4.3% | 12,303,252 | $269.1M |
| Avoro Capital Advisors LLC | 4.17% | No change | 12,222,222 | $267.3M |
| EcoR1 Capital, LLC | 15.47% | Add +0.0% | 11,895,808 | $260.2M |
| Vanguard Group Inc. | 0.00% | Add +0.8% | 10,130,356 | $221.6M |
| Morgan Stanley | 0.02% | Reduce -0.0% | 9,626,123 | $210.5M |
| BlackRock, Inc. | 0.00% | Reduce -2.3% | 6,329,598 | $138.4M |
| Deep Track Capital, LP | 3.54% | Add +17.0% | 5,000,000 | $109.3M |
| AQR Capital Management | 0.09% | Add +119.6% | 4,077,419 | $89.2M |
| State Street Corp. | 0.00% | Reduce -12.9% | 3,941,405 | $86.2M |
| UBS Group AG | 0.02% | Add +26.5% | 3,272,194 | $71.6M |
| Bank of America Corp. | 0.01% | Add +86.4% | 3,131,436 | $68.5M |
| Siren, L.L.C. | 3.18% | Reduce -8.4% | 2,578,396 | $56.4M |
| Jennison Associates LLC | 0.04% | Reduce -10.3% | 2,477,531 | $54.2M |
| Octagon Capital Advisors LP | 9.95% | Reduce -30.4% | 2,094,000 | $45.8M |
| Geode Capital Management, LLC | 0.00% | Add +6.0% | 1,950,046 | $42.7M |
| Deutsche Bank AG | 0.02% | Reduce -0.1% | 1,776,576 | $38.9M |
| Braidwell LP | 1.88% | Reduce -21.3% | 1,652,334 | $36.1M |
| Montanova Capital, LLC | 1.46% | Add +107.6% | 1,646,615 | $36.0M |
| Polar Capital Holdings Plc | 0.21% | No change | 1,577,175 | $34.5M |
| Norges Bank | 0.00% | Add +44.9% | 1,573,601 | $34.4M |
| FMR LLC | 0.00% | Reduce -29.4% | 1,503,209 | $32.9M |
| Orbimed Advisors LLC | 0.75% | New | 1,432,300 | $31.3M |
| BNP Paribas Financial Markets | 0.02% | Add +30.6% | 1,110,709 | $24.3M |
| Canada Pension Plan Investment Board | 0.02% | Add +2879.3% | 1,048,700 | $22.9M |
| Man Group plc | 0.07% | Add +1985.1% | 1,027,792 | $22.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Reduce -3.2% | 964,499 | $21.1M |
| Royal Bank of Canada | 0.00% | Reduce -47.7% | 794,935 | $17.4M |
| National Bank of Canada | 0.02% | Reduce -43.5% | 782,701 | $17.1M |
| Boxer Capital Management, LLC | 4.69% | Reduce -50.0% | 713,000 | $15.6M |
| Natixis | 0.09% | Reduce -24.8% | 655,027 | $14.8M |
| Invesco Ltd. | 0.00% | Add +6.3% | 641,397 | $14.0M |
| Jefferies Financial Group Inc. | 0.24% | Add +75.5% | 599,255 | $13.1M |
| Northern Trust Corp. | 0.00% | Reduce -5.2% | 518,694 | $11.3M |
| Nuveen, LLC | 0.00% | — | 492,238 | $10.8M |
| Ameriprise Financial Inc. | 0.00% | Reduce -47.1% | 466,661 | $10.2M |
| Millennium Management | 0.01% | Reduce -21.5% | 451,973 | $9.9M |
| Squarepoint Ops LLC | 0.02% | Add +165.2% | 442,793 | $9.7M |
| JPMorgan Chase & Co. | 0.00% | Add +3.0% | 423,800 | $9.3M |
| Citigroup Inc. | 0.01% | Add +116.8% | 416,619 | $9.1M |
| Trexquant Investment LP | 0.10% | Add +89.6% | 384,922 | $8.4M |
| SG Americas Securities, LLC | 0.03% | Add +598.7% | 366,144 | $8.0M |
| Pictet Asset Management Holding SA | 0.01% | Reduce -9.5% | 314,842 | $7.6M |
| Amundi | 0.00% | No change | 329,582 | $7.4M |
| Algert Global LLC | 0.18% | Add +19.9% | 338,613 | $7.4M |
| 683 Capital Management, LLC | 0.81% | Reduce -7.5% | 333,000 | $7.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -1.6% | 329,173 | $7.2M |
| Balyasny Asset Management L.P. | 0.02% | Reduce -56.4% | 324,487 | $7.1M |
| Walleye Capital LLC | 0.09% | Reduce -19.6% | 317,442 | $6.9M |
| Hudson Bay Capital Management LP | 0.05% | Reduce -9.9% | 310,700 | $6.8M |
| Goldman Sachs Group Inc. | 0.00% | Add +26.6% | 307,709 | $6.7M |
| Ieq Capital, LLC | 0.05% | Add +130.3% | 291,858 | $6.4M |
| Schroder Investment Management Group | 0.01% | Add +15.4% | 253,109 | $6.1M |
| Jump Financial, LLC | 0.09% | New | 265,593 | $5.8M |
| Two Sigma Investments, LP | 0.01% | New | 262,904 | $5.7M |
| Jane Street Group, LLC | 0.01% | Add +166.8% | 256,092 | $5.6M |
| Voloridge Investment Management, LLC | 0.02% | Reduce -26.6% | 253,790 | $5.6M |
| ExodusPoint Capital Management, LP | 0.07% | New | 250,414 | $5.5M |
| Edgestream Partners, L.P. | 0.18% | Add +119.6% | 241,287 | $5.3M |
| Citadel Advisors | 0.00% | Add +99.3% | 224,096 | $4.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +4.6% | 222,634 | $4.9M |
| Woodline Partners LP | 0.03% | Add +15.5% | 218,850 | $4.8M |
| Prudential Financial Inc. | 0.01% | Add +10.0% | 217,880 | $4.8M |
| Aquatic Capital Management LLC | 0.12% | Add +67.1% | 215,876 | $4.7M |
| Victory Capital Management Inc. | 0.00% | Reduce -61.7% | 215,152 | $4.7M |
| Macquarie Group Ltd. | 0.01% | Add +1.9% | 204,803 | $4.5M |
| Fiduciary Trust Co | 0.06% | Reduce -11.5% | 203,336 | $4.4M |
| First Trust Advisors LP | 0.00% | Add +676.8% | 199,209 | $4.4M |
| PDT Partners, LLC | 0.30% | Add +41.7% | 195,165 | $4.3M |
| Two Sigma Advisers, LP | 0.01% | New | 191,800 | $4.2M |
| Barclays PLC | 0.00% | Add +19.9% | 191,237 | $4.2M |
| ING Groep NV | 0.03% | New | 184,200 | $4.0M |
| Schonfeld Strategic Advisors LLC | 0.03% | New | 181,400 | $4.0M |
| Sphera Funds Management LTD. | 0.98% | Reduce -12.1% | 181,346 | $4.0M |
| Rafferty Asset Management, LLC | 0.02% | Reduce -25.4% | 180,134 | $3.9M |
| Granahan Investment Management, LLC | 0.19% | Add +13.8% | 175,696 | $3.8M |
| Toronto Dominion Bank | 0.01% | Reduce -83.7% | 162,190 | $3.5M |
| Candriam S.C.A. | 0.02% | Reduce -70.5% | 159,054 | $3.5M |
| Bank of Montreal | 0.00% | Add +95.8% | 158,573 | $3.5M |
| Alyeska Investment Group, L.P. | 0.01% | New | 150,000 | $3.3M |
| Swiss National Bank | 0.00% | Reduce -7.7% | 132,600 | $2.9M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +878.6% | 131,895 | $2.9M |
| Old West Investment Management, LLC | 1.01% | Add +12.8% | 128,192 | $2.8M |
| California Public Employees Retirement System | 0.00% | Add +0.0% | 126,706 | $2.8M |
| Voya Investment Management LLC | 0.00% | Add +1.8% | 125,401 | $2.7M |
| Rhumbline Advisers | 0.00% | Reduce -0.9% | 124,454 | $2.7M |
| Steward Partners Investment Advisory, LLC | 0.02% | Add +6.2% | 122,175 | $2.7M |
| Verition Fund Management LLC | 0.01% | Add +119.2% | 110,510 | $2.4M |
| HighVista Strategies LLC | 0.92% | No change | 108,714 | $2.4M |
| Cwm, LLC | 0.01% | Add +120.3% | 98,258 | $2.1M |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 91,818 | $2.0M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -74.7% | 90,700 | $2.0M |
| State of Wisconsin Investment Board | 0.00% | Add +5.3% | 84,615 | $1.9M |
| Rock Springs Capital Management LP | 0.10% | No change | 80,000 | $1.7M |
| Legal & General Group Plc | 0.00% | Reduce -8.9% | 79,070 | $1.7M |
| Ikarian Capital, LLC | 0.53% | Add +1986.8% | 75,000 | $1.6M |
| Assenagon Asset Management S.A. | 0.00% | Add +147.8% | 74,325 | $1.6M |
| Bleakley Financial Group, LLC | 0.05% | Reduce -0.5% | 73,137 | $1.6M |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +108.8% | 70,159 | $1.5M |
| California State Teachers Retirement System | 0.00% | Reduce -15.4% | 59,778 | $1.3M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 55,000 | $1.3M |
"% of holder's portfolio" is APLS's weight in each manager's 13F, not the share of Apellis Pharmaceuticals Inc. the manager owns.