Apellis PharmaceuticalsAPLS
13F holders, Q4 2024 (December 31)260holders −5
48new positions
62sold out
7famous investors
$31.91avg. 13F price*
At the end of Q4 2024, 260 institutions reported holding Apellis Pharmaceuticals Inc. (APLS) in their 13F filings, down 5 from Q3 2024. 48 opened new positions and 62 sold out. The largest holders were Avoro Capital Advisors LLC ($390.0M), EcoR1 Capital, LLC ($379.4M) and Wellington Management Group LLP ($376.6M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Cliff Asness (0.1% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Apellis Pharmaceuticals Inc.
- CUSIP
- 03753U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 48 | $238.7M |
| Exits | 62 | $134.7M |
All 13F filers, Q3 2024 → Q4 2024: 30,166,297 shares bought and 21,374,307 shares sold, net +8,791,990 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 260 holders
| Avoro Capital Advisors LLC | 5.52% | Add +10.0% | 12,222,222 | $390.0M |
| EcoR1 Capital, LLC | 15.18% | No change | 11,890,843 | $379.4M |
| Wellington Management Group LLP | 0.07% | Reduce -24.2% | 11,800,849 | $376.6M |
| Vanguard Group Inc. | 0.01% | Add +2.4% | 10,046,025 | $320.6M |
| Morgan Stanley | 0.02% | Add +184.0% | 9,627,227 | $307.2M |
| BlackRock, Inc. | 0.00% | Add +4.6% | 6,477,989 | $206.7M |
| State Street Corp. | 0.01% | Add +12.0% | 4,525,155 | $144.4M |
| Deep Track Capital, LP | 5.11% | Reduce -2.9% | 4,274,921 | $136.4M |
| Octagon Capital Advisors LP | 16.34% | No change | 3,006,980 | $96.0M |
| Siren, L.L.C. | 3.97% | Add +29.9% | 2,816,258 | $89.9M |
| Jennison Associates LLC | 0.05% | Add +51.6% | 2,760,404 | $88.1M |
| UBS Group AG | 0.02% | Add +722.0% | 2,586,739 | $82.5M |
| FMR LLC | 0.00% | Reduce -26.6% | 2,127,665 | $67.9M |
| Braidwell LP | 2.99% | Reduce -32.8% | 2,098,866 | $67.0M |
| AQR Capital Management | 0.08% | Add +127.2% | 1,856,442 | $59.2M |
| Geode Capital Management, LLC | 0.00% | Add +1.6% | 1,838,952 | $58.7M |
| Deutsche Bank AG | 0.02% | Add +1.8% | 1,778,377 | $56.7M |
| Bank of America Corp. | 0.01% | Add +72.3% | 1,680,213 | $53.6M |
| Polar Capital Holdings Plc | 0.28% | Add +45.8% | 1,577,175 | $50.3M |
| Royal Bank of Canada | 0.01% | Add +969.6% | 1,518,827 | $48.5M |
| Boxer Capital Management, LLC | 3.87% | — | 1,426,000 | $45.5M |
| National Bank of Canada | 0.06% | Add +266361.5% | 1,385,600 | $44.2M |
| Cibc World Markets Corp. | 0.24% | New | 1,285,300 | $41.0M |
| Point72 Asset Management | 0.11% | New | 1,267,958 | $40.5M |
| Norges Bank | 0.00% | Add +1.7% | 1,086,243 | $34.7M |
| Toronto Dominion Bank | 0.06% | Add +3791.4% | 997,053 | $31.8M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +4.2% | 996,748 | $31.8M |
| Ameriprise Financial Inc. | 0.01% | Add +2.6% | 882,801 | $28.2M |
| Natixis | 0.19% | New | 870,627 | $27.8M |
| BNP Paribas Financial Markets | 0.02% | Add +432.8% | 850,823 | $27.1M |
| Montanova Capital, LLC | 0.94% | New | 793,187 | $25.3M |
| Balyasny Asset Management L.P. | 0.06% | New | 744,194 | $23.7M |
| Invesco Ltd. | 0.00% | Reduce -0.1% | 603,656 | $19.3M |
| Millennium Management | 0.02% | Add +643.7% | 575,490 | $18.4M |
| Victory Capital Management Inc. | 0.02% | Add +36.5% | 562,269 | $17.9M |
| Northern Trust Corp. | 0.00% | Add +20.8% | 547,276 | $17.5M |
| Candriam S.C.A. | 0.10% | Reduce -20.6% | 539,602 | $17.2M |
| Logos Global Management LP | 1.87% | New | 500,000 | $16.0M |
| Nuveen Asset Management, LLC | 0.00% | Add +44.1% | 491,107 | $15.7M |
| Integral Health Asset Management, LLC | 1.19% | New | 420,000 | $13.4M |
| JPMorgan Chase & Co. | 0.00% | Reduce -89.4% | 411,549 | $13.1M |
| Walleye Capital LLC | 0.13% | Add +286.8% | 394,823 | $12.6M |
| 683 Capital Management, LLC | 1.26% | Add +53.2% | 360,000 | $11.5M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -5.3% | 358,578 | $11.4M |
| Pictet Asset Management Holding SA | 0.01% | Add +16.8% | 347,854 | $11.1M |
| Voloridge Investment Management, LLC | 0.04% | Reduce -57.5% | 345,885 | $11.0M |
| Hudson Bay Capital Management LP | 0.08% | Add +32.7% | 345,000 | $11.0M |
| Jefferies Financial Group Inc. | 0.13% | Add +603.7% | 341,361 | $10.9M |
| Amundi | 0.00% | Add +10967.2% | 329,582 | $10.9M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.7% | 334,416 | $10.7M |
| MUFG Securities EMEA plc | 0.18% | New | 298,000 | $9.5M |
| Algert Global LLC | 0.21% | Add +242.5% | 282,285 | $9.0M |
| Renaissance Technologies | 0.01% | Reduce -27.0% | 271,913 | $8.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +24.6% | 242,967 | $7.8M |
| Rafferty Asset Management, LLC | 0.03% | Add +18.3% | 241,474 | $7.7M |
| Fiduciary Trust Co | 0.10% | Reduce -2.6% | 229,801 | $7.3M |
| Schroder Investment Management Group | 0.01% | No change | 219,383 | $7.0M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +11.4% | 212,887 | $6.8M |
| Sphera Funds Management LTD. | 1.22% | Reduce -4.5% | 206,251 | $6.6M |
| Trexquant Investment LP | 0.08% | New | 203,008 | $6.5M |
| Macquarie Group Ltd. | 0.01% | Add +9.7% | 201,067 | $6.4M |
| Intrinsic Edge Capital Management LLC | 0.87% | New | 200,000 | $6.4M |
| Prudential Financial Inc. | 0.01% | Reduce -31.2% | 198,060 | $6.3M |
| Rhenman & Partners Asset Management AB | 0.64% | Reduce -46.8% | 195,591 | $6.2M |
| Point72 Europe (London) LLP | 0.36% | New | 192,694 | $6.1M |
| Citigroup Inc. | 0.01% | Add +1480.0% | 192,161 | $6.1M |
| Cubist Systematic Strategies, LLC | 0.10% | New | 191,687 | $6.1M |
| Woodline Partners LP | 0.04% | Add +0.5% | 189,477 | $6.0M |
| Squarepoint Ops LLC | 0.01% | Add +84.8% | 166,962 | $5.3M |
| Barclays PLC | 0.00% | Reduce -37.6% | 159,565 | $5.1M |
| Granahan Investment Management, LLC | 0.21% | Add +2.5% | 154,418 | $4.9M |
| Swiss National Bank | 0.00% | Reduce -6.8% | 143,700 | $4.6M |
| PDT Partners, LLC | 0.39% | Reduce -5.4% | 137,694 | $4.4M |
| Aquatic Capital Management LLC | 0.11% | Add +5283.7% | 129,209 | $4.1M |
| HSBC Holdings PLC | 0.00% | Add +7.9% | 127,828 | $4.1M |
| Ieq Capital, LLC | 0.04% | Add +1425.5% | 126,710 | $4.0M |
| California Public Employees Retirement System | 0.00% | Reduce -8.0% | 126,659 | $4.0M |
| Rhumbline Advisers | 0.00% | Reduce -0.2% | 125,560 | $4.0M |
| Voya Investment Management LLC | 0.00% | Add +40.0% | 123,151 | $3.9M |
| Capital Fund Management S.A. | 0.04% | Reduce -50.1% | 121,433 | $3.9M |
| Exome Asset Management LLC | 2.87% | Add +19.0% | 119,467 | $3.8M |
| Steward Partners Investment Advisory, LLC | 0.03% | Add +2.0% | 115,045 | $3.7M |
| Old West Investment Management, LLC | 1.47% | Add +11.0% | 113,623 | $3.6M |
| Citadel Advisors | 0.00% | Reduce -43.3% | 112,423 | $3.6M |
| Edgestream Partners, L.P. | 0.15% | Add +10.6% | 109,883 | $3.5M |
| HighVista Strategies LLC | 1.29% | Add +202.2% | 108,714 | $3.5M |
| KBC Group NV | 0.01% | Add +3862.3% | 104,287 | $3.3M |
| Banque Pictet & Cie SA | 0.03% | Add +31.7% | 97,299 | $3.1M |
| Jane Street Group, LLC | 0.00% | Add +397.9% | 95,985 | $3.1M |
| State Board of Administration of Florida Retirement System | 0.01% | No change | 91,818 | $2.9M |
| Cinctive Capital Management LP | 0.15% | New | 86,991 | $2.8M |
| Legal & General Group Plc | 0.00% | Reduce -1.4% | 86,771 | $2.8M |
| Marshall Wace, LLP | 0.00% | Add +292.4% | 85,495 | $2.7M |
| Bank of Montreal | 0.00% | Add +105.8% | 80,991 | $2.6M |
| State of Wisconsin Investment Board | 0.01% | Reduce -0.8% | 80,382 | $2.6M |
| Rock Springs Capital Management LP | 0.10% | No change | 80,000 | $2.6M |
| Ensign Peak Advisors, Inc | 0.00% | Reduce -2.4% | 79,097 | $2.5M |
| Bleakley Financial Group, LLC | 0.07% | Reduce -6.9% | 73,505 | $2.3M |
| California State Teachers Retirement System | 0.00% | Reduce -7.7% | 70,688 | $2.3M |
| Fieldview Capital Management, LLC | 0.30% | — | 61,405 | $2.0M |
"% of holder's portfolio" is APLS's weight in each manager's 13F, not the share of Apellis Pharmaceuticals Inc. the manager owns.