Apellis PharmaceuticalsAPLS
13F holders, Q1 2026 (March 31)324holders +44
116new positions
75sold out
11famous investors
$39.63avg. 13F price*
At the end of Q1 2026, 324 institutions reported holding Apellis Pharmaceuticals Inc. (APLS) in their 13F filings, up 44 from Q4 2025. 116 opened new positions and 75 sold out. The largest holders were BlackRock, Inc. ($544.6M), Avoro Capital Advisors LLC ($491.7M) and Morgan Stanley ($404.0M). 11 famous investors held it, including George Soros (0.8% of Soros Fund Management's portfolio), Steve Cohen (0.3% of Point72 Asset Management's portfolio) and Paul Tudor Jones (0.1% of Tudor Investment Corporation's portfolio).
- Company
- Apellis Pharmaceuticals Inc.
- CUSIP
- 03753U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 116 | $1.1B |
| Exits | 75 | $404.7M |
All 13F filers, Q4 2025 → Q1 2026: 57,101,717 shares bought and 44,527,637 shares sold, net +12,574,080 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 324 holders
| BlackRock, Inc. | 0.01% | Add +116.2% | 13,536,964 | $544.6M |
| Avoro Capital Advisors LLC | 4.84% | No change | 12,222,222 | $491.7M |
| Morgan Stanley | 0.02% | Add +9.5% | 10,042,399 | $404.0M |
| State Street Corp. | 0.01% | Add +48.4% | 6,844,990 | $275.4M |
| UBS Group AG | 0.04% | Add +48.3% | 6,206,681 | $249.7M |
| Vanguard Portfolio Management LLC | 0.01% | — | 5,404,559 | $217.4M |
| Pentwater Capital Management LP | 1.50% | New | 5,250,000 | $211.2M |
| Vanguard Capital Management LLC | 0.00% | — | 4,768,944 | $191.9M |
| Deep Track Capital, LP | 3.76% | Reduce -41.5% | 4,532,374 | $182.3M |
| Point72 Asset Management | 0.31% | Add +600.0% | 4,183,918 | $168.3M |
| RTW Investments, LP | 1.48% | Reduce -51.9% | 3,685,045 | $148.2M |
| HBK Investments L P | 1.95% | New | 3,550,000 | $142.8M |
| Montanova Capital, LLC | 3.84% | Reduce -15.0% | 3,518,471 | $141.5M |
| Millennium Management | 0.07% | Add +138.4% | 2,256,802 | $90.8M |
| Geode Capital Management, LLC | 0.01% | Add +2.4% | 2,075,075 | $83.5M |
| Goldman Sachs Group Inc. | 0.01% | Add +946.6% | 1,980,144 | $79.7M |
| Balyasny Asset Management L.P. | 0.16% | Add +2844.0% | 1,917,501 | $77.1M |
| Dimensional Fund Advisors LP | 0.01% | Add +640.1% | 1,338,995 | $53.7M |
| Glazer Capital, LLC | 1.16% | New | 1,294,196 | $52.1M |
| TIG Advisors, LLC | 2.41% | New | 1,252,986 | $50.4M |
| Toronto Dominion Bank | 0.10% | New | 1,236,436 | $49.7M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.08% | New | 1,202,100 | $48.4M |
| Bank of America Corp. | 0.00% | Add +24.5% | 1,190,864 | $47.9M |
| Hudson Bay Capital Management LP | 0.32% | Add +0.9% | 1,190,416 | $47.9M |
| FIL Ltd | 0.04% | New | 1,140,000 | $45.9M |
| Kryger Capital LLC | 3.13% | — | 1,100,000 | $44.3M |
| Soros Fund Management | 0.78% | New | 1,056,000 | $42.5M |
| Capitolis Liquid Global Markets LLC | 0.26% | — | 1,013,500 | $40.8M |
| Woodline Partners LP | 0.15% | Add +79.8% | 976,175 | $39.3M |
| Renaissance Technologies | 0.06% | Add +47.9% | 935,958 | $37.7M |
| Marshall Wace, LLP | 0.04% | Reduce -6.2% | 929,019 | $37.4M |
| Man Group plc | 0.08% | Add +534.7% | 915,689 | $36.8M |
| First Trust Advisors LP | 0.03% | Add +82.2% | 903,637 | $36.4M |
| JPMorgan Chase & Co. | 0.00% | Add +1198.2% | 2,047,927 | $35.0M |
| Magnetar Financial LLC | 0.38% | New | 869,229 | $35.0M |
| Alpine Associates Management Inc. | 2.05% | New | 864,000 | $34.8M |
| Kynam Capital Management, LP | 2.11% | Reduce -9.2% | 825,000 | $33.2M |
| Oddo BHF Asset Management Sas | 1.31% | New | 825,000 | $33.2M |
| Northern Trust Corp. | 0.00% | Add +6.0% | 738,440 | $29.7M |
| Weiss Asset Management LP | 0.72% | New | 700,000 | $28.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.9% | 675,864 | $27.2M |
| Citigroup Inc. | 0.02% | Add +5.6% | 657,223 | $26.4M |
| Vanguard Fiduciary Trust Co. | 0.01% | — | 654,922 | $26.3M |
| Tudor Investment Corporation | 0.14% | Add +202.3% | 650,000 | $26.1M |
| BNP Paribas Financial Markets | 0.02% | Add +4.8% | 584,192 | $23.5M |
| Ossiam | 0.39% | Add +28.8% | 555,953 | $22.4M |
| Bank of New York Mellon Corp | 0.00% | Add +93.0% | 524,789 | $21.1M |
| Two Sigma Investments, LP | 0.02% | Reduce -7.2% | 521,965 | $21.0M |
| Principal Financial Group Inc. | 0.01% | New | 499,053 | $20.1M |
| Absolute Gestao de Investimentos Ltda. | 2.07% | New | 450,000 | $18.1M |
| Squarepoint Ops LLC | 0.04% | Add +134.1% | 449,796 | $18.1M |
| Invesco Ltd. | 0.00% | Add +93.8% | 437,868 | $17.6M |
| AQR Capital Management | 0.01% | Reduce -81.2% | 427,970 | $17.2M |
| LMR Partners LLP | 0.19% | New | 403,622 | $16.2M |
| Verition Fund Management LLC | 0.17% | New | 400,000 | $16.1M |
| Alliancebernstein L.P. | 0.01% | Add +1748.5% | 638,291 | $16.0M |
| Public Sector Pension Investment Board | 0.05% | New | 366,674 | $14.8M |
| First Trust Capital Management L.P. | 0.74% | New | 350,800 | $14.1M |
| Susquehanna International Group, LLP | 0.02% | Reduce -36.3% | 340,086 | $13.7M |
| Gabelli Funds LLC | 0.09% | New | 321,200 | $12.9M |
| Beck Bode, LLC | 2.13% | New | 312,841 | $12.6M |
| Meteora Capital, LLC | 0.90% | New | 300,000 | $12.1M |
| O'Connor Alternative Investments LLC | 0.68% | — | 300,000 | $12.1M |
| Jump Financial, LLC | 0.19% | Add +50.4% | 291,488 | $11.7M |
| Rhumbline Advisers | 0.01% | Add +135.7% | 275,540 | $11.1M |
| Janus Henderson Group PLC | 0.00% | Add +9.5% | 252,130 | $10.1M |
| 683 Capital Management, LLC | 0.98% | Reduce -24.2% | 250,000 | $10.1M |
| Capstone Investment Advisors, LLC | 0.11% | New | 250,000 | $10.1M |
| Wellington Management Group LLP | 0.00% | Reduce -98.0% | 249,635 | $10.0M |
| Granite Investment Partners, LLC | 0.57% | Reduce -29.1% | 231,917 | $9.3M |
| Legal & General Group Plc | 0.00% | Add +167.0% | 228,255 | $9.2M |
| Westchester Capital Management, LLC | 0.44% | New | 227,489 | $9.2M |
| Nuveen, LLC | 0.00% | Reduce -67.7% | 220,114 | $8.9M |
| Jefferies Financial Group Inc. | 0.11% | Add +2412.0% | 219,000 | $8.8M |
| Bank of Montreal | 0.00% | Add +21.8% | 215,041 | $8.7M |
| Sphera Funds Management LTD. | 1.49% | Reduce -14.4% | 214,914 | $8.6M |
| Trexquant Investment LP | 0.06% | Add +5.5% | 205,219 | $8.3M |
| GABELLI & Co INVESTMENT ADVISERS, INC. | 1.20% | New | 200,600 | $8.1M |
| Pictet Asset Management Holding SA | 0.01% | Add +9.2% | 426,821 | $7.6M |
| D. E. Shaw & Co. | 0.01% | Reduce -58.5% | 186,853 | $7.5M |
| Ameriprise Financial Inc. | 0.00% | Reduce -68.9% | 183,578 | $7.4M |
| Boothbay Fund Management, LLC | 0.18% | Add +757.0% | 183,522 | $7.4M |
| Rafferty Asset Management, LLC | 0.03% | Add +5.3% | 180,471 | $7.3M |
| Fiduciary Trust Co | 0.09% | Reduce -0.1% | 180,161 | $7.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +0.6% | 179,953 | $7.2M |
| Gardner Lewis Asset Management L P | 1.44% | New | 165,000 | $6.6M |
| Rock Springs Capital Management LP | 0.39% | Add +8.1% | 162,750 | $6.5M |
| Mackenzie Financial Corp. | 0.01% | Add +59.4% | 153,330 | $6.2M |
| Picton Mahoney Asset Management | 0.06% | New | 150,000 | $6.0M |
| Swiss National Bank | 0.00% | No change | 149,500 | $6.0M |
| Empowered Funds, LLC | 0.04% | Add +1006.3% | 148,038 | $6.0M |
| AQR Arbitrage LLC | 0.12% | New | 146,604 | $5.9M |
| Chicago Capital Management, LLC | 12.18% | New | 190,000 | $5.8M |
| Slotnik Capital, LLC | 1.61% | New | 135,000 | $5.4M |
| Twin Securities, Inc. | 2.53% | New | 127,440 | $5.1M |
| Royal Bank of Canada | 0.00% | Add +42.9% | 126,701 | $5.1M |
| Schonfeld Strategic Advisors LLC | 0.04% | New | 123,824 | $5.0M |
| Quantinno Capital Management LP | 0.01% | Add +281.8% | 121,270 | $4.9M |
| Water Island Capital LLC | 0.68% | New | 120,500 | $4.8M |
| Prelude Capital Management, LLC | 0.34% | Add +189.4% | 111,468 | $4.5M |
"% of holder's portfolio" is APLS's weight in each manager's 13F, not the share of Apellis Pharmaceuticals Inc. the manager owns.