Apellis PharmaceuticalsAPLS
13F holders, Q2 2025 (June 30)247holders −8
39new positions
49sold out
6famous investors
$17.32avg. 13F price*
At the end of Q2 2025, 247 institutions reported holding Apellis Pharmaceuticals Inc. (APLS) in their 13F filings, down 8 from Q1 2025. 39 opened new positions and 49 sold out. The largest holders were Avoro Capital Advisors LLC ($211.6M), EcoR1 Capital, LLC ($205.9M) and Vanguard Group Inc. ($175.8M). 6 famous investors held it, including Cliff Asness (0.1% of AQR Capital Management's portfolio), Joel Greenblatt (0.0% of Gotham Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Apellis Pharmaceuticals Inc.
- CUSIP
- 03753U106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 39 | $65.6M |
| Exits | 49 | $96.4M |
All 13F filers, Q1 2025 → Q2 2025: 20,772,156 shares bought and 17,257,692 shares sold, net +3,514,464 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 247 holders
| Avoro Capital Advisors LLC | 3.71% | No change | 12,222,222 | $211.6M |
| EcoR1 Capital, LLC | 12.22% | No change | 11,895,808 | $205.9M |
| Vanguard Group Inc. | 0.00% | Add +0.2% | 10,154,751 | $175.8M |
| Morgan Stanley | 0.01% | Add +1.3% | 9,752,201 | $168.8M |
| Wellington Management Group LLP | 0.03% | Reduce -27.0% | 8,976,962 | $155.4M |
| Deep Track Capital, LP | 3.90% | Add +40.0% | 7,000,000 | $121.2M |
| BlackRock, Inc. | 0.00% | Add +1.2% | 6,404,999 | $110.9M |
| AQR Capital Management | 0.09% | Add +46.6% | 5,976,414 | $103.5M |
| UBS Group AG | 0.02% | Add +44.7% | 4,735,311 | $82.0M |
| State Street Corp. | 0.00% | Reduce -9.6% | 3,562,721 | $61.7M |
| Montanova Capital, LLC | 1.88% | Add +74.8% | 2,878,000 | $49.8M |
| Marshall Wace, LLP | 0.06% | Add +11373.8% | 2,704,837 | $46.8M |
| Jennison Associates LLC | 0.03% | Add +7.4% | 2,661,823 | $46.1M |
| Siren, L.L.C. | 2.31% | No change | 2,578,396 | $44.6M |
| Bank of America Corp. | 0.00% | Reduce -22.5% | 2,426,628 | $42.0M |
| Norges Bank | 0.01% | Add +50.4% | 2,367,224 | $41.0M |
| Geode Capital Management, LLC | 0.00% | Add +2.3% | 1,995,271 | $34.5M |
| Amundi | 0.01% | Add +386.7% | 1,604,105 | $28.6M |
| Deutsche Bank AG | 0.01% | Reduce -15.8% | 1,496,296 | $25.9M |
| Orbimed Advisors LLC | 0.65% | Add +3.5% | 1,482,300 | $25.7M |
| Polar Capital Holdings Plc | 0.12% | Reduce -14.3% | 1,352,175 | $23.4M |
| BNP Paribas Financial Markets | 0.02% | Add +16.9% | 1,298,459 | $22.5M |
| Braidwell LP | 0.93% | Reduce -32.1% | 1,121,034 | $19.4M |
| Wells Fargo & Company | 0.00% | Add +22470.4% | 1,043,655 | $18.1M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +2.6% | 989,143 | $17.1M |
| Octagon Capital Advisors LP | 3.43% | Reduce -56.9% | 903,500 | $15.6M |
| Camber Capital Management LP | 2.05% | New | 850,000 | $14.7M |
| Royal Bank of Canada | 0.00% | Add +0.3% | 797,585 | $13.8M |
| Ameriprise Financial Inc. | 0.00% | Add +60.8% | 750,161 | $13.0M |
| Bank of Nova Scotia | 0.02% | New | 594,812 | $10.3M |
| Jefferies Financial Group Inc. | 0.17% | Reduce -3.5% | 578,205 | $10.0M |
| Jump Financial, LLC | 0.12% | Add +110.3% | 558,668 | $9.7M |
| Ossiam | 0.11% | New | 555,953 | $9.6M |
| Capitolis Liquid Global Markets LLC | 0.07% | New | 544,600 | $9.4M |
| Woodline Partners LP | 0.05% | Add +142.6% | 530,923 | $9.2M |
| Northern Trust Corp. | 0.00% | Add +1.4% | 525,882 | $9.1M |
| Schroder Investment Management Group | 0.01% | Add +91.9% | 485,615 | $8.4M |
| Hudson Bay Capital Management LP | 0.06% | Add +52.9% | 475,000 | $8.2M |
| Nuveen, LLC | 0.00% | Reduce -4.7% | 469,253 | $8.1M |
| Voloridge Investment Management, LLC | 0.03% | Add +84.7% | 468,710 | $8.1M |
| Citadel Advisors | 0.01% | Add +97.5% | 442,560 | $7.7M |
| 683 Capital Management, LLC | 0.76% | Add +23.1% | 410,000 | $7.1M |
| Two Sigma Investments, LP | 0.01% | Add +54.8% | 406,913 | $7.0M |
| Pictet Asset Management Holding SA | 0.01% | Add +10.6% | 348,349 | $6.1M |
| Ieq Capital, LLC | 0.04% | Add +18.9% | 346,923 | $6.0M |
| Canada Pension Plan Investment Board | 0.01% | Reduce -67.9% | 336,800 | $5.8M |
| Squarepoint Ops LLC | 0.01% | Reduce -25.6% | 329,392 | $5.7M |
| Susquehanna International Group, LLP | 0.01% | Add +1014.1% | 328,726 | $5.7M |
| Trexquant Investment LP | 0.06% | Reduce -14.9% | 327,421 | $5.7M |
| ING Groep NV | 0.03% | Add +67.4% | 308,300 | $5.3M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +35.6% | 301,939 | $5.2M |
| Barclays PLC | 0.00% | Add +43.2% | 273,912 | $4.7M |
| Two Sigma Advisers, LP | 0.01% | Add +33.9% | 256,800 | $4.4M |
| D. E. Shaw & Co. | 0.00% | New | 251,069 | $4.3M |
| Jane Street Group, LLC | 0.01% | Reduce -3.9% | 246,199 | $4.3M |
| Bank of New York Mellon Corp | 0.00% | Reduce -26.1% | 243,327 | $4.2M |
| JPMorgan Chase & Co. | 0.00% | Reduce -44.6% | 234,801 | $4.1M |
| Caption Management, LLC | 0.37% | Add +1824.1% | 230,888 | $4.0M |
| Edgestream Partners, L.P. | 0.11% | Reduce -9.5% | 218,392 | $3.8M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -29.8% | 215,999 | $3.7M |
| Fiduciary Trust Co | 0.04% | Reduce -0.4% | 202,536 | $3.5M |
| Millennium Management | 0.00% | Reduce -55.2% | 202,452 | $3.5M |
| Aquatic Capital Management LLC | 0.06% | Reduce -18.1% | 176,704 | $3.1M |
| Invesco Ltd. | 0.00% | Reduce -74.1% | 166,135 | $2.9M |
| Y-Intercept (Hong Kong) Ltd | 0.07% | Add +455.4% | 164,275 | $2.8M |
| PDT Partners, LLC | 0.16% | Reduce -18.0% | 160,058 | $2.8M |
| Bank of Montreal | 0.00% | Add +0.7% | 159,613 | $2.8M |
| Algert Global LLC | 0.06% | Reduce -54.5% | 154,113 | $2.7M |
| Prudential Financial Inc. | 0.00% | Reduce -29.3% | 154,010 | $2.7M |
| Voya Investment Management LLC | 0.00% | Add +20.1% | 150,593 | $2.6M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -20.1% | 143,852 | $2.5M |
| Swiss National Bank | 0.00% | Add +8.4% | 143,800 | $2.5M |
| Steward Partners Investment Advisory, LLC | 0.02% | Add +15.4% | 140,975 | $2.4M |
| Citigroup Inc. | 0.00% | Reduce -66.8% | 138,451 | $2.4M |
| California Public Employees Retirement System | 0.00% | Add +6.3% | 134,637 | $2.3M |
| Cwm, LLC | 0.01% | Add +29.9% | 127,584 | $2.2M |
| Rhumbline Advisers | 0.00% | Reduce -2.0% | 122,002 | $2.1M |
| Gotham Asset Management | 0.01% | Add +247.8% | 119,229 | $2.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Reduce -10.0% | 118,724 | $2.1M |
| J. Safra Sarasin Holding AG | 0.03% | Add +145.6% | 115,684 | $2.0M |
| Cerity Partners LLC | 0.00% | Add +110.8% | 114,745 | $2.0M |
| Sphera Funds Management LTD. | 0.52% | Reduce -37.0% | 114,346 | $2.0M |
| HRT Financial LP | 0.01% | New | 107,200 | $1.9M |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Add +43.5% | 100,666 | $1.8M |
| EFG Asset Management (North America) Corp. | 0.26% | Add +166.8% | 105,024 | $1.8M |
| Dark Forest Capital Management LP | 0.07% | New | 104,725 | $1.8M |
| Exome Asset Management LLC | 1.41% | New | 98,600 | $1.7M |
| Legal & General Group Plc | 0.00% | Add +21.5% | 96,050 | $1.7M |
| Verition Fund Management LLC | 0.01% | Reduce -13.5% | 95,605 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Add +11.6% | 94,404 | $1.6M |
| J. Goldman & Co LP | 0.05% | New | 93,574 | $1.6M |
| Rhenman & Partners Asset Management AB | 0.20% | Add +230.1% | 93,250 | $1.6M |
| T. Rowe Price Associates Inc. | 0.00% | Add +1.6% | 92,151 | $1.6M |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -0.5% | 91,408 | $1.6M |
| Natixis | 0.01% | Reduce -86.2% | 90,666 | $1.6M |
| California State Teachers Retirement System | 0.00% | Add +47.1% | 87,929 | $1.5M |
| HighVista Strategies LLC | 0.55% | Reduce -20.3% | 86,663 | $1.5M |
| Rock Springs Capital Management LP | 0.09% | Add +5.4% | 84,300 | $1.5M |
| Schonfeld Strategic Advisors LLC | 0.01% | Reduce -53.7% | 83,916 | $1.5M |
| Walleye Capital LLC | 0.01% | Reduce -74.4% | 81,270 | $1.4M |
"% of holder's portfolio" is APLS's weight in each manager's 13F, not the share of Apellis Pharmaceuticals Inc. the manager owns.