Centessa PharmaceuticalsCNTA
13F holders, Q3 2025 (September 30)At the end of Q3 2025, 125 institutions reported holding Centessa Pharmaceuticals Ltd. (CNTA) in their 13F filings, up 8 from Q2 2025. 27 opened new positions and 17 sold out. The largest holders were Medicxi Ventures Management (Jersey) Ltd ($484.1M), Avoro Capital Advisors LLC ($262.1M) and Adage Capital Partners Gp, L.L.C. ($243.3M). 6 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio).
- Company
- Centessa Pharmaceuticals Ltd.
- CUSIP
- 152309100
- Latest filing quarter
- Q1 2026
History
Number of 13F holders
Total Exit/New Position Q2 2025 → Q3 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 27 | $104.0M |
| Exits | 17 | $36.5M |
All 13F filers, Q2 2025 → Q3 2025: 19,015,662 shares bought and 14,200,117 shares sold, net +4,815,545 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 125 holders
| Medicxi Ventures Management (Jersey) Ltd | 65.03% | No change | 19,963,157 | $484.1M |
| Avoro Capital Advisors LLC | 3.39% | Add +116.2% | 10,808,080 | $262.1M |
| Adage Capital Partners Gp, L.L.C. | 0.39% | Add +19.4% | 10,035,000 | $243.3M |
| Index Venture Life Associates VI Ltd | 100.00% | No change | 9,961,789 | $241.6M |
| General Atlantic, L.P. | 7.05% | No change | 9,681,818 | $234.8M |
| FMR LLC | 0.01% | Add +64.1% | 6,277,243 | $152.2M |
| Janus Henderson Group PLC | 0.06% | Reduce -17.2% | 5,408,199 | $131.1M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -18.7% | 4,804,056 | $116.5M |
| Farallon Capital Management, L.L.C. | 0.59% | Reduce -4.4% | 4,331,318 | $105.0M |
| First Light Asset Management, LLC | 8.31% | Reduce -15.3% | 3,635,816 | $88.2M |
| Siren, L.L.C. | 3.06% | Reduce -6.7% | 3,227,517 | $78.3M |
| TCG Crossover Management, LLC | 3.74% | Add +8.5% | 3,136,480 | $76.1M |
| Perceptive Advisors LLC | 2.21% | Add +170.4% | 3,100,902 | $75.2M |
| Commodore Capital LP | 3.37% | Reduce -13.6% | 2,850,000 | $69.1M |
| Franklin Resources Inc. | 0.02% | Add +0.6% | 2,558,414 | $62.0M |
| RTW Investments, LP | 0.68% | Add +49.8% | 2,291,747 | $55.6M |
| Cormorant Asset Management, LP | 3.22% | Reduce -7.7% | 1,925,000 | $46.7M |
| Federated Hermes, Inc. | 0.07% | New | 1,749,650 | $42.4M |
| Foresite Capital Management VI LLC | 12.31% | Add +4.8% | 1,314,019 | $31.9M |
| Morgan Stanley | 0.00% | Reduce -37.3% | 1,124,445 | $27.3M |
| Affinity Asset Advisors, LLC | 2.58% | Add +23.0% | 1,107,162 | $26.8M |
| American Century Companies Inc. | 0.01% | Reduce -3.0% | 1,096,704 | $26.6M |
| Point72 Asset Management | 0.06% | Reduce -58.6% | 1,072,665 | $26.0M |
| Millennium Management | 0.02% | Reduce -45.6% | 902,268 | $21.9M |
| Octagon Capital Advisors LP | 3.14% | Reduce -19.4% | 830,000 | $20.1M |
| Balyasny Asset Management L.P. | 0.04% | Reduce -34.0% | 805,611 | $19.5M |
| Saturn V Capital Management LP | 3.91% | Reduce -7.4% | 734,539 | $17.8M |
| Capital World Investors | 0.00% | Add +64.3% | 684,805 | $16.6M |
| 5AM Venture Management, LLC | 6.05% | Reduce -18.1% | 680,945 | $16.5M |
| PFM Health Sciences, LP | 1.40% | Add +93.1% | 666,196 | $16.2M |
| Stempoint Capital LP | 3.20% | Reduce -48.2% | 655,385 | $15.9M |
| Tanager Wealth Management LLP | 1.52% | No change | 598,044 | $14.5M |
| Ensign Peak Advisors, Inc | 0.02% | No change | 559,744 | $13.6M |
| Bank of America Corp. | 0.00% | Add +307.2% | 553,007 | $13.4M |
| EcoR1 Capital, LLC | 0.64% | New | 550,000 | $13.3M |
| Logos Global Management LP | 1.26% | New | 525,000 | $12.7M |
| Driehaus Capital Management LLC | 0.09% | Add +1.0% | 515,979 | $12.5M |
| TD Asset Management Inc | 0.01% | Reduce -15.6% | 466,960 | $11.3M |
| BlackRock, Inc. | 0.00% | Add +7.2% | 408,386 | $9.9M |
| Nantahala Capital Management, LLC | 0.61% | Reduce -27.0% | 404,803 | $9.8M |
| Armistice Capital, LLC | 0.29% | Reduce -5.5% | 378,000 | $9.2M |
| Candriam S.C.A. | 0.04% | Reduce -1.3% | 343,207 | $8.3M |
| Manufacturers Life Insurance Company, The | 0.01% | Reduce -17.4% | 262,146 | $6.4M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -55.7% | 247,555 | $6.0M |
| Royce & Associates LP | 0.06% | New | 247,387 | $6.0M |
| Jain Global LLC | 0.08% | New | 241,975 | $5.9M |
| JPMorgan Chase & Co. | 0.00% | Reduce -43.5% | 241,895 | $5.9M |
| HighMark Wealth Management LLC | 2.53% | No change | 237,285 | $5.8M |
| Tang Capital Management LLC | 0.19% | Add +300.0% | 200,000 | $4.8M |
| Fred Alger Management, LLC | 0.02% | Add +53.8% | 190,360 | $4.6M |
| Platinum Investment Management Ltd. | 0.29% | Reduce -35.9% | 186,399 | $4.5M |
| Russell Investments Group, Ltd. | 0.01% | Add +29.3% | 182,300 | $4.4M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +46.1% | 172,696 | $4.2M |
| Blue Owl Capital Holdings LP | 1.28% | Reduce -48.7% | 169,450 | $4.1M |
| Renaissance Technologies | 0.01% | Reduce -57.2% | 164,600 | $4.0M |
| Windmill Hill Asset Management Ltd | 1.04% | No change | 163,768 | $4.0M |
| Silverarc Capital Management, LLC | 0.50% | Add +2724.8% | 141,238 | $3.4M |
| Citadel Advisors | 0.00% | New | 137,201 | $3.3M |
| Artia Global Partners LP | 0.57% | New | 133,291 | $3.2M |
| Caption Management, LLC | 0.18% | New | 125,309 | $3.0M |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 0.00% | Reduce -54.8% | 116,397 | $2.8M |
| Verition Fund Management LLC | 0.02% | New | 114,306 | $2.8M |
| Marshall Wace, LLP | 0.00% | Reduce -66.9% | 113,590 | $2.8M |
| Ameriprise Financial Inc. | 0.00% | New | 108,002 | $2.6M |
| Woodline Partners LP | 0.01% | Reduce -73.1% | 107,671 | $2.6M |
| Cubist Systematic Strategies, LLC | 0.04% | Reduce -62.4% | 103,909 | $2.5M |
| Eagle Health Investments LP | 0.66% | New | 103,100 | $2.5M |
| Legal & General Group Plc | 0.00% | Add +3.5% | 101,693 | $2.5M |
| Geode Capital Management, LLC | 0.00% | Add +8.7% | 95,032 | $2.3M |
| Cinctive Capital Management LP | 0.11% | New | 92,628 | $2.2M |
| Exome Asset Management LLC | 1.41% | Reduce -47.3% | 88,024 | $2.1M |
| UBS Group AG | 0.00% | Reduce -59.4% | 85,178 | $2.1M |
| Wellington Management Group LLP | 0.00% | Reduce -44.7% | 82,665 | $2.0M |
| Rock Springs Capital Management LP | 0.10% | New | 69,240 | $1.7M |
| D. E. Shaw & Co. | 0.00% | Add +308.5% | 64,389 | $1.6M |
| HighVista Strategies LLC | 0.38% | Add +55.6% | 63,301 | $1.5M |
| Trexquant Investment LP | 0.02% | Reduce -58.8% | 62,310 | $1.5M |
| Tudor Investment Corporation | 0.01% | Add +13.7% | 57,810 | $1.4M |
| Two Sigma Investments, LP | 0.00% | Reduce -20.4% | 57,444 | $1.4M |
| ADAR1 Capital Management, LLC | 0.13% | Reduce -81.9% | 53,666 | $1.3M |
| Aberdeen Group plc | 0.00% | Reduce -55.1% | 53,574 | $1.3M |
| Voya Investment Management LLC | 0.00% | No change | 29,670 | $719K |
| Prelude Capital Management, LLC | 0.05% | Reduce -46.8% | 26,656 | $646K |
| Campbell & CO Investment Adviser LLC | 0.05% | Add +55.5% | 25,845 | $627K |
| Jane Street Group, LLC | 0.00% | Reduce -74.5% | 24,091 | $584K |
| SG Americas Securities, LLC | 0.00% | New | 23,586 | $572K |
| Boothbay Fund Management, LLC | 0.01% | Reduce -49.1% | 21,319 | $517K |
| Squarepoint Ops LLC | 0.00% | Reduce -51.2% | 19,413 | $471K |
| Gsa Capital Partners LLP | 0.04% | New | 18,761 | $455K |
| Meridian Wealth Partners, LLC | 0.06% | Reduce -52.5% | 18,101 | $439K |
| OMERS ADMINISTRATION Corp | 0.00% | Reduce -68.3% | 17,500 | $424K |
| China Universal Asset Management Co., Ltd. | 0.03% | Reduce -12.3% | 16,816 | $408K |
| Pictet Asset Management Holding SA | 0.00% | New | 13,869 | $336K |
| Atria Investments, Inc | 0.00% | Reduce -3.0% | 13,518 | $328K |
| J. Goldman & Co LP | 0.01% | Reduce -60.5% | 13,105 | $318K |
| Coastal Bridge Advisors, LLC | 0.02% | Reduce -33.3% | 13,102 | $318K |
| Virtus Investment Advisers, LLC | 0.07% | Add +21.0% | 9,451 | $229K |
| DNB Asset Management AS | 0.00% | New | 8,988 | $218K |
| Bank of New York Mellon Corp | 0.00% | New | 8,727 | $212K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.03% | New | 6,690 | $162K |
| Royal Bank of Canada | 0.00% | Reduce -27.9% | 5,404 | $131K |
| Barclays PLC | 0.00% | Reduce -33.9% | 4,968 | $120K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +716.5% | 3,911 | $95K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +0.5% | 3,709 | $90K |
| GAMMA Investing LLC | 0.00% | Add +13.2% | 3,612 | $88K |
| Rockefeller Capital Management L.P. | 0.00% | New | 3,468 | $84K |
| Simplex Trading, LLC | 0.00% | New | 2,622 | $63K |
| Group One Trading LLC | 0.00% | New | 2,461 | $60K |
| Wells Fargo & Company | 0.00% | Add +1486.0% | 2,379 | $58K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -9.6% | 2,064 | $50K |
| Citigroup Inc. | 0.00% | Add +1.3% | 1,844 | $45K |
| BNP Paribas Financial Markets | 0.00% | Reduce -96.6% | 1,198 | $29K |
| Adirondack Trust Co. | 0.01% | No change | 925 | $22K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Reduce -29.5% | 481 | $12K |
| Global Retirement Partners, LLC | 0.00% | No change | 350 | $8K |
| Daiwa Securities Group Inc. | 0.00% | No change | 294 | $7K |
| Aspect Partners, LLC | 0.00% | New | 230 | $6K |
| Washington Trust Advisors, Inc. | 0.00% | No change | 184 | $4K |
| Lanark Financial, Inc. | 0.00% | No change | 138 | $3K |
| Steward Partners Investment Advisory, LLC | 0.00% | New | 81 | $2K |
| Bellevue Asset Management, LLC | 0.00% | New | 70 | $2K |
| T. Rowe Price Investment Management, Inc. | 0.00% | Reduce -95.0% | 20 | $1K |
| SBI Securities Co., Ltd. | 0.00% | New | 21 | $509 |
| EverSource Wealth Advisors, LLC | 0.00% | No change | 20 | $485 |
| Principal Securities, Inc. | 0.00% | No change | 17 | $412 |
"% of holder's portfolio" is CNTA's weight in each manager's 13F, not the share of Centessa Pharmaceuticals Ltd. the manager owns.