Crinetics PharmaceuticalsCRNX

13F holders, Q4 2025 (December 31)
242holders +17
40new positions
27sold out
4famous investors
$46.55avg. 13F price*

At the end of Q4 2025, 242 institutions reported holding Crinetics Pharmaceuticals Inc. (CRNX) in their 13F filings, up 17 from Q3 2025. 40 opened new positions and 27 sold out. The largest holders were FMR LLC ($665.4M), Vanguard Group Inc. ($425.3M) and Wellington Management Group LLP ($374.2M). 4 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Crinetics Pharmaceuticals Inc.
CUSIP
22663K107
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 203Q1 2024Q2 2024: 234Q2 2024Q3 2024: 235Q3 2024Q4 2024: 247Q4 2024Q1 2025: 227Q1 2025Q2 2025: 222Q2 2025Q3 2025: 225Q3 2025Q4 2025: 242Q4 2025Q1 2026: 244Q1 2026Q2 2026: 267Q2 2026

Total Exit/New Position Q3 2025 → Q4 2025

InstitutionsTotal Value
New Positions40$41.1M
Exits27$74.9M

All 13F filers, Q3 2025 → Q4 2025: 9,730,519 shares bought and 5,909,003 shares sold, net +3,821,516 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 242 holders

FMR LLC 0.03% Add +0.8% 14,293,775 $665.4M
Vanguard Group Inc. 0.01% Reduce -0.4% 9,135,504 $425.3M
Wellington Management Group LLP 0.07% Reduce -4.1% 8,037,889 $374.2M
BlackRock, Inc. 0.01% Add +5.3% 7,988,548 $371.9M
Farallon Capital Management, L.L.C. 1.68% Add +20.2% 6,933,098 $322.7M
Driehaus Capital Management LLC 2.02% Reduce -1.4% 6,387,740 $297.3M
T. Rowe Price Associates Inc. 0.03% Reduce -1.5% 5,224,387 $243.2M
Janus Henderson Group PLC 0.09% Add +15.1% 4,440,691 $206.6M
EcoR1 Capital, LLC 9.15% No change 4,288,120 $199.6M
Point72 Asset Management 0.18% Add +16.7% 2,337,034 $108.8M
Geode Capital Management, LLC 0.01% Reduce -1.6% 2,242,631 $104.4M
Paradigm Biocapital Advisors LP 2.76% Reduce -13.3% 2,210,774 $102.9M
State Street Corp. 0.00% Reduce -2.1% 2,161,378 $100.6M
Baker Bros. Advisors LP 0.45% Add +488.9% 1,648,869 $76.8M
Novo Holdings A/S 5.87% No change 1,625,000 $75.6M
Pictet Asset Management Holding SA 0.07% Add +6.5% 1,560,300 $72.6M
Siren, L.L.C. 2.09% Reduce -10.7% 1,507,636 $70.2M
GW&K Investment Management, LLC 0.59% Add +73.6% 1,476,325 $68.7M
RTW Investments, LP 0.63% Add +54.9% 1,351,326 $62.9M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.07% Add +59.1% 1,327,382 $61.8M
Jennison Associates LLC 0.04% Reduce -37.3% 1,281,601 $59.7M
First Light Asset Management, LLC 4.25% Add +26.8% 1,194,263 $55.6M
JPMorgan Chase & Co. 0.00% Reduce -8.3% 1,154,710 $53.8M
American Century Companies Inc. 0.03% Reduce -5.7% 1,068,878 $49.8M
Orbimed Advisors LLC 0.95% Reduce -9.1% 999,000 $46.5M
UBS Group AG 0.01% Add +122.8% 908,192 $42.3M
Hood River Capital Management LLC 0.46% Add +1.6% 897,403 $41.8M
Candriam S.C.A. 0.19% Add +11.5% 830,961 $38.7M
Bank of America Corp. 0.00% Add +33.3% 801,314 $37.3M
Charles Schwab Investment Management Inc. 0.01% Add +0.4% 781,981 $36.4M
Northern Trust Corp. 0.00% Reduce -5.0% 769,823 $35.8M
Morgan Stanley 0.00% Add +12.7% 768,826 $35.8M
Fisher Asset Management 0.01% Add +0.0% 758,659 $35.3M
Aberdeen Group plc 0.05% Add +98.4% 674,533 $31.4M
Ameriprise Financial Inc. 0.01% Reduce -2.2% 601,190 $28.0M
Fiera Capital Corp 0.09% Add +32.9% 578,455 $26.9M
Goldman Sachs Group Inc. 0.00% Reduce -20.5% 567,127 $26.4M
Dimensional Fund Advisors LP 0.01% Add +45.3% 548,977 $25.6M
Nuveen, LLC 0.01% Reduce -4.1% 522,466 $24.3M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.03% Add +5.3% 408,312 $19.0M
Bank of New York Mellon Corp 0.00% Add +1.4% 405,010 $18.9M
ADAR1 Capital Management, LLC 1.08% Add +24.6% 309,368 $14.4M
Voya Investment Management LLC 0.02% Add +770.5% 302,001 $14.1M
Millennium Management 0.01% Add +38.9% 300,335 $14.0M
Cormorant Asset Management, LP 0.79% Reduce -25.0% 300,000 $14.0M
Ensign Peak Advisors, Inc 0.02% Reduce -6.6% 275,616 $12.8M
Impax Asset Management Group plc 0.08% New 275,000 $12.8M
Prosight Management, LP 2.53% Reduce -20.0% 262,904 $12.2M
Citadel Advisors 0.01% Reduce -71.2% 254,720 $11.9M
Deutsche Bank AG 0.00% Add +1.1% 235,018 $10.9M
Balyasny Asset Management L.P. 0.02% Add +1560.4% 233,197 $10.9M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +3.7% 225,842 $10.5M
GordonMD Global Investments LP 7.48% — 224,135 $10.4M
Skandinaviska Enskilda Banken AB (publ) 0.04% Add +19.8% 213,891 $10.0M
Schroder Investment Management Group 0.01% Add +114.7% 187,433 $8.9M
TD Asset Management Inc 0.01% Reduce -6.4% 190,478 $8.9M
Segall Bryant & Hamill, LLC 0.12% Add +4.8% 189,477 $8.8M
Barclays PLC 0.00% Add +1.3% 185,677 $8.6M
Neuberger Berman Group LLC 0.01% Add +171.3% 182,188 $8.5M
Swiss National Bank 0.00% Add +2.3% 176,500 $8.2M
Rice Hall James & Associates, LLC 0.44% Reduce -1.3% 171,830 $8.0M
Invesco Ltd. 0.00% Add +76.8% 158,089 $7.4M
Manufacturers Life Insurance Company, The 0.01% Add +0.5% 148,489 $7.0M
New York State Common Retirement Fund 0.01% Reduce -1.4% 146,123 $6.8M
Silvercrest Asset Management Group LLC 0.05% New 144,239 $6.7M
Wells Fargo & Company 0.00% Add +41.3% 139,461 $6.5M
Victory Capital Management Inc. 0.00% Reduce -40.6% 138,685 $6.5M
Envestnet Asset Management Inc. 0.00% Add +147.5% 130,363 $6.1M
Sio Capital Management, LLC 0.96% Reduce -28.6% 124,841 $5.8M
Russell Investments Group, Ltd. 0.01% Reduce -19.5% 119,905 $5.6M
Rhumbline Advisers 0.00% Reduce -12.0% 115,752 $5.4M
Sector Gamma As 1.22% New 115,000 $5.4M
Moody Aldrich Partners LLC 0.96% Reduce -4.4% 110,415 $5.1M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +701.7% 100,567 $4.7M
AWM Investment Company, Inc. 0.45% No change 100,000 $4.7M
Alliancebernstein L.P. 0.00% No change 93,020 $4.3M
Decheng Capital LLC 0.58% Reduce -35.2% 92,700 $4.3M
Legal & General Group Plc 0.00% Reduce -6.4% 87,802 $4.1M
California State Teachers Retirement System 0.00% Add +1.6% 85,568 $4.0M
Alps Advisors Inc. 0.02% Add +64.0% 77,765 $3.6M
Affinity Asset Advisors, LLC 0.26% No change 75,000 $3.5M
Sei Investments Co. 0.00% Add +19.4% 72,045 $3.4M
Castleark Management LLC 0.09% New 62,790 $2.9M
Man Group plc 0.01% New 62,560 $2.9M
T. Rowe Price Investment Management, Inc. 0.00% Reduce -2.4% 59,121 $2.8M
State of Wisconsin Investment Board 0.01% Reduce -2.6% 55,561 $2.6M
Phocas Financial Corp. 0.33% Reduce -0.3% 53,877 $2.5M
MetLife Investment Management, LLC 0.01% Reduce -6.7% 49,818 $2.3M
Two Sigma Investments, LP 0.00% No change 49,699 $2.3M
Creative Planning 0.00% Add +16.6% 47,321 $2.2M
Royal Bank of Canada 0.00% Reduce -72.3% 47,295 $2.2M
Vestmark Advisory Solutions, Inc. 0.03% New 46,552 $2.2M
Lisanti Capital Growth, LLC 0.47% Add +88.0% 43,040 $2.0M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -0.0% 42,002 $2.0M
Susquehanna International Group, LLP 0.00% Reduce -87.0% 33,511 $1.6M
Raymond James Financial Inc. 0.00% New 33,354 $1.6M
First Trust Advisors LP 0.00% Add +378.3% 33,150 $1.5M
State of New Jersey Common Pension Fund D 0.01% Reduce -57.8% 30,537 $1.4M
Orion Porfolio Solutions, LLC 0.01% Add +80.8% 30,495 $1.4M
Intech Investment Management LLC 0.01% Add +36.1% 30,243 $1.4M
Handelsbanken Fonder AB 0.00% Reduce -8.1% 29,500 $1.4M
WINTON GROUP Ltd 0.05% Reduce -58.4% 28,384 $1.3M
BNP Paribas Financial Markets 0.00% Add +14.9% 27,533 $1.3M
Teachers Retirement System of the State of Kentucky 0.01% No change 27,377 $1.3M
Lewis Asset Management, LLC 0.49% Reduce -12.0% 26,105 $1.2M
Pathstone Holdings, LLC 0.00% Add +9.6% 25,062 $1.2M
Arizona State Retirement System 0.01% Reduce -4.9% 25,014 $1.2M
Police & Firemen's Retirement System of New Jersey 0.01% Reduce -0.8% 24,820 $1.2M
Progeny 3, Inc. 0.06% New 24,000 $1.1M
Headlands Technologies LLC 0.09% Add +14.8% 23,217 $1.1M
Parkman Healthcare Partners LLC 0.10% Reduce -69.0% 22,852 $1.1M
SG Americas Securities, LLC 0.00% Reduce -32.5% 21,789 $1.0M
HighMark Wealth Management LLC 0.41% Add +7.5% 21,495 $1.0M
Stifel Financial Corp. 0.00% Reduce -2.5% 21,200 $987K
ProShare Advisors LLC 0.00% Add +10.2% 20,721 $965K
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +7.9% 20,116 $936K
Natixis Advisors, LLC 0.00% Reduce -61.3% 20,035 $933K
KLP Kapitalforvaltning As 0.00% Add +1.6% 19,100 $889K
Cerity Partners LLC 0.00% New 18,974 $883K
State Board of Administration of Florida Retirement System 0.00% No change 18,406 $857K
Assetmark, Inc. 0.00% Reduce -4.6% 17,965 $836K
Oppenheimer Asset Management Inc. 0.01% Add +235.8% 17,786 $828K
Franklin Resources Inc. 0.00% Reduce -13.4% 17,671 $823K
Glenmede Trust Co. NA 0.00% — 16,944 $789K
Citigroup Inc. 0.00% Reduce -21.4% 16,337 $760K
DNB Asset Management AS 0.00% Add +75.7% 16,089 $749K
Legato Capital Management LLC 0.06% Add +182.1% 16,035 $746K
Cresset Asset Management, LLC 0.00% Add +6.5% 15,858 $738K
Odyssean, LLC 0.53% — 15,848 $738K
AlphaQuest LLC 0.04% Add +7.7% 15,844 $738K
China Universal Asset Management Co., Ltd. 0.06% Reduce -6.3% 15,463 $720K
Virtus Investment Advisers, LLC 0.17% Add +282.7% 13,535 $630K
Teacher Retirement System of Texas 0.00% Reduce -39.3% 13,219 $615K
DekaBank Deutsche Girozentrale 0.00% No change 11,300 $546K
PSP Research LLC 0.46% — 11,316 $527K
Los Angeles Capital Management LLC 0.00% Add +19.4% 11,267 $488K
Truist Financial Corp. 0.00% New 9,879 $460K
Public Employees Retirement Association of Colorado 0.00% No change 9,008 $419K
Fiduciary Trust Co 0.00% Add +19.9% 8,897 $414K
Quantinno Capital Management LP 0.00% Add +13.4% 8,856 $412K
Canada Pension Plan Investment Board 0.00% New 8,829 $411K
Tema ETFs LLC 0.03% Reduce -60.7% 8,767 $408K
NEOS Investment Management LLC 0.00% Reduce -60.7% 8,767 $408K
Baader Bank Aktiengesellschaft 0.03% New 8,625 $399K
Vanguard Personalized Indexing Management, LLC 0.00% Add +13.9% 8,524 $397K
CANADA LIFE ASSURANCE Co 0.00% Reduce -63.6% 8,214 $382K
Commerce Bank 0.00% Add +5.9% 8,019 $373K
Ameritas Investment Partners, Inc. 0.01% Reduce -2.9% 7,340 $342K
Xponance LLC 0.00% Add +1.4% 7,195 $335K
Park Avenue Securities LLC 0.00% New 7,040 $328K
Profund Advisors LLC 0.01% Reduce -31.1% 6,950 $324K
Rwa Wealth Partners, LLC 0.00% Add +20.2% 6,846 $319K
Advisors Asset Management, Inc. 0.01% Reduce -1.3% 6,569 $306K
LPL Financial LLC 0.00% New 6,154 $286K
Tower Research Capital LLC (TRC) 0.01% Add +114.1% 6,123 $285K
Brooklyn Investment Group 0.01% New 5,890 $280K
Cibc World Markets Corp. 0.00% — 5,982 $278K
Oppenheimer & Co. Inc. 0.00% Add +14.9% 5,973 $278K
Palumbo Wealth Management LLC 0.07% New 5,805 $270K
Praxis Investment Management Inc. 0.02% No change 5,805 $270K
Mackenzie Financial Corp. 0.00% Reduce -4.6% 5,666 $268K
Amundi 0.00% New 5,622 $262K
Prudential Financial Inc. 0.00% Reduce -51.7% 5,615 $261K
US Bancorp \de 0.00% Add +7.9% 5,511 $257K
MML Investors Services, LLC 0.00% New 5,394 $251K
Keybank National Association 0.00% Reduce -34.1% 5,357 $249K
Principal Financial Group Inc. 0.00% Reduce -22.9% 5,341 $249K
STRS Ohio 0.00% Add +341.7% 5,300 $247K
PNC Financial Services Group, Inc. 0.00% Reduce -11.5% 5,270 $245K
Atria Investments, Inc 0.00% Add +1.0% 5,139 $239K
Callan Family Office, LLC 0.01% New 5,002 $233K
Walleye Capital LLC 0.00% New 4,931 $230K
Rafferty Asset Management, LLC 0.00% Reduce -21.3% 4,865 $226K
Cetera Investment Advisers 0.00% New 4,810 $224K
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 0.03% New 4,717 $220K
Rockefeller Capital Management L.P. 0.00% Add +12.5% 4,679 $218K
Snowden Capital Advisors LLC 0.01% Reduce -4.3% 4,668 $217K
Meeder Advisory Services, Inc. 0.01% New 4,646 $216K
OneDigital Investment Advisors LLC 0.00% New 4,622 $215K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +26.6% 4,611 $215K
Bellevue Group AG 0.00% New 4,040 $188K
Comerica Bank 0.00% Add +420.1% 3,396 $158K
Nisa Investment Advisors, LLC 0.00% Add +0.1% 3,202 $149K
Bessemer Group Inc. 0.00% Add +0.3% 3,111 $145K
KBC Group NV 0.00% No change 3,064 $143K
Kestra Advisory Services, LLC 0.00% New 2,922 $136K
Amalgamated Bank 0.00% Reduce -3.0% 2,841 $132K
GF Fund Management Co. LTD. 0.00% Reduce -8.0% 1,864 $87K
Osaic Holdings, Inc. 0.00% Reduce -30.4% 1,756 $82K
Arax Advisory Partners 0.00% Add +131.2% 1,498 $70K
IFP Advisors, Inc 0.00% No change 1,446 $67K
Parallel Advisors, LLC 0.00% Add +34.6% 1,225 $57K
State of Wyoming 0.00% Reduce -31.4% 669 $31K
Smartleaf Asset Management LLC 0.00% Add +107.5% 639 $30K
Huntington National Bank 0.00% Add +4.0% 619 $29K
Sterling Capital Management LLC 0.00% Add +171.7% 595 $28K
Signaturefd, LLC 0.00% Add +32.5% 514 $24K
GAMMA Investing LLC 0.00% Add +97.4% 460 $21K
Farther Finance Advisors, LLC 0.00% Reduce -46.8% 448 $21K
Wellington-Altus USA Inc. 0.01% — 395 $18K
Larson Financial Group LLC 0.00% Add +354.7% 291 $14K
Daiwa Securities Group Inc. 0.00% Reduce -7.2% 282 $13K
Allworth Financial LP 0.00% Add +14.6% 252 $12K
Kemnay Advisory Services Inc. 0.00% New 234 $11K
Quadrant Capital Group LLC 0.00% No change 230 $11K
MAI Capital Management 0.00% New 215 $10K
SBI Securities Co., Ltd. 0.00% New 210 $10K
MassMutual Private Wealth & Trust, FSB 0.00% Reduce -22.1% 201 $9K
Cwm, LLC 0.00% Add +101.2% 173 $8K
Optiver Holding B.V. 0.00% Reduce -37.6% 166 $8K
Basecamp Wealth Advisors LLC 0.00% — 163 $8K
Aster Capital Management (DIFC) Ltd 0.00% New 158 $7K
ORG Partners LLC 0.00% Add +440.7% 146 $7K
J.Safra Asset Management Corp 0.00% Add +21.9% 117 $5K
EverSource Wealth Advisors, LLC 0.00% Add +64.2% 110 $5K
SageView Advisory Group, LLC 0.00% New 110 $5K
Versant Capital Management, Inc 0.00% No change 104 $5K
Rothschild Investment LLC 0.00% No change 100 $5K
Danske Bank A/S 0.00% No change 100 $5K
Parkside Financial Bank & Trust 0.00% Add +33.3% 60 $3K
Jones Financial Companies LLLP 0.00% New 58 $3K
Pinnacle Wealth Planning Services, Inc. 0.00% New 55 $3K
Meeder Asset Management Inc. 0.00% Reduce -58.5% 49 $2K
Bare Financial Services, Inc 0.00% New 47 $2K
Cornerstone Planning Group LLC 0.00% No change 42 $2K
Motiv8 Investments LLC 0.00% New 35 $2K
Cornerstone Financial Management LLC 0.00% — 34 $2K
Cape Investment Advisory, Inc. 0.00% No change 31 $1K
Quarry LP 0.00% New 30 $1K
Whittier Trust Co. of Nevada Inc. 0.00% No change 30 $1K
Torren Management, LLC 0.00% — 23 $1K
Zions Bancorporation, National Association 0.00% New 22 $1K
Park Place Capital Corp 0.00% No change 18 $838
Bell Investment Advisors, Inc 0.00% Reduce -37.0% 17 $792
Physician Wealth Advisors, Inc. 0.00% Reduce -31.8% 15 $699
CoreCap Advisors, LLC 0.00% New 14 $652
Ares Financial Consulting, LLC 0.00% — 12 $559
True Wealth Design, LLC 0.00% No change 8 $373
Keating Financial Advisory Services, Inc. 0.00% — 4 $186
Dunhill Financial, LLC 0.00% New 2 $79
Inspire Investing, LLC 0.00% New 1 $29
Covestor Ltd 0.00% Reduce -99.7% 5 $0

"% of holder's portfolio" is CRNX's weight in each manager's 13F, not the share of Crinetics Pharmaceuticals Inc. the manager owns.