Crinetics PharmaceuticalsCRNX
13F holders, Q4 2025 (December 31)At the end of Q4 2025, 242 institutions reported holding Crinetics Pharmaceuticals Inc. (CRNX) in their 13F filings, up 17 from Q3 2025. 40 opened new positions and 27 sold out. The largest holders were FMR LLC ($665.4M), Vanguard Group Inc. ($425.3M) and Wellington Management Group LLP ($374.2M). 4 famous investors held it, including Steve Cohen (0.2% of Point72 Asset Management's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Crinetics Pharmaceuticals Inc.
- CUSIP
- 22663K107
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2025 → Q4 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 40 | $41.1M |
| Exits | 27 | $74.9M |
All 13F filers, Q3 2025 → Q4 2025: 9,730,519 shares bought and 5,909,003 shares sold, net +3,821,516 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 242 holders
| FMR LLC | 0.03% | Add +0.8% | 14,293,775 | $665.4M |
| Vanguard Group Inc. | 0.01% | Reduce -0.4% | 9,135,504 | $425.3M |
| Wellington Management Group LLP | 0.07% | Reduce -4.1% | 8,037,889 | $374.2M |
| BlackRock, Inc. | 0.01% | Add +5.3% | 7,988,548 | $371.9M |
| Farallon Capital Management, L.L.C. | 1.68% | Add +20.2% | 6,933,098 | $322.7M |
| Driehaus Capital Management LLC | 2.02% | Reduce -1.4% | 6,387,740 | $297.3M |
| T. Rowe Price Associates Inc. | 0.03% | Reduce -1.5% | 5,224,387 | $243.2M |
| Janus Henderson Group PLC | 0.09% | Add +15.1% | 4,440,691 | $206.6M |
| EcoR1 Capital, LLC | 9.15% | No change | 4,288,120 | $199.6M |
| Point72 Asset Management | 0.18% | Add +16.7% | 2,337,034 | $108.8M |
| Geode Capital Management, LLC | 0.01% | Reduce -1.6% | 2,242,631 | $104.4M |
| Paradigm Biocapital Advisors LP | 2.76% | Reduce -13.3% | 2,210,774 | $102.9M |
| State Street Corp. | 0.00% | Reduce -2.1% | 2,161,378 | $100.6M |
| Baker Bros. Advisors LP | 0.45% | Add +488.9% | 1,648,869 | $76.8M |
| Novo Holdings A/S | 5.87% | No change | 1,625,000 | $75.6M |
| Pictet Asset Management Holding SA | 0.07% | Add +6.5% | 1,560,300 | $72.6M |
| Siren, L.L.C. | 2.09% | Reduce -10.7% | 1,507,636 | $70.2M |
| GW&K Investment Management, LLC | 0.59% | Add +73.6% | 1,476,325 | $68.7M |
| RTW Investments, LP | 0.63% | Add +54.9% | 1,351,326 | $62.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.07% | Add +59.1% | 1,327,382 | $61.8M |
| Jennison Associates LLC | 0.04% | Reduce -37.3% | 1,281,601 | $59.7M |
| First Light Asset Management, LLC | 4.25% | Add +26.8% | 1,194,263 | $55.6M |
| JPMorgan Chase & Co. | 0.00% | Reduce -8.3% | 1,154,710 | $53.8M |
| American Century Companies Inc. | 0.03% | Reduce -5.7% | 1,068,878 | $49.8M |
| Orbimed Advisors LLC | 0.95% | Reduce -9.1% | 999,000 | $46.5M |
| UBS Group AG | 0.01% | Add +122.8% | 908,192 | $42.3M |
| Hood River Capital Management LLC | 0.46% | Add +1.6% | 897,403 | $41.8M |
| Candriam S.C.A. | 0.19% | Add +11.5% | 830,961 | $38.7M |
| Bank of America Corp. | 0.00% | Add +33.3% | 801,314 | $37.3M |
| Charles Schwab Investment Management Inc. | 0.01% | Add +0.4% | 781,981 | $36.4M |
| Northern Trust Corp. | 0.00% | Reduce -5.0% | 769,823 | $35.8M |
| Morgan Stanley | 0.00% | Add +12.7% | 768,826 | $35.8M |
| Fisher Asset Management | 0.01% | Add +0.0% | 758,659 | $35.3M |
| Aberdeen Group plc | 0.05% | Add +98.4% | 674,533 | $31.4M |
| Ameriprise Financial Inc. | 0.01% | Reduce -2.2% | 601,190 | $28.0M |
| Fiera Capital Corp | 0.09% | Add +32.9% | 578,455 | $26.9M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -20.5% | 567,127 | $26.4M |
| Dimensional Fund Advisors LP | 0.01% | Add +45.3% | 548,977 | $25.6M |
| Nuveen, LLC | 0.01% | Reduce -4.1% | 522,466 | $24.3M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.03% | Add +5.3% | 408,312 | $19.0M |
| Bank of New York Mellon Corp | 0.00% | Add +1.4% | 405,010 | $18.9M |
| ADAR1 Capital Management, LLC | 1.08% | Add +24.6% | 309,368 | $14.4M |
| Voya Investment Management LLC | 0.02% | Add +770.5% | 302,001 | $14.1M |
| Millennium Management | 0.01% | Add +38.9% | 300,335 | $14.0M |
| Cormorant Asset Management, LP | 0.79% | Reduce -25.0% | 300,000 | $14.0M |
| Ensign Peak Advisors, Inc | 0.02% | Reduce -6.6% | 275,616 | $12.8M |
| Impax Asset Management Group plc | 0.08% | New | 275,000 | $12.8M |
| Prosight Management, LP | 2.53% | Reduce -20.0% | 262,904 | $12.2M |
| Citadel Advisors | 0.01% | Reduce -71.2% | 254,720 | $11.9M |
| Deutsche Bank AG | 0.00% | Add +1.1% | 235,018 | $10.9M |
| Balyasny Asset Management L.P. | 0.02% | Add +1560.4% | 233,197 | $10.9M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +3.7% | 225,842 | $10.5M |
| GordonMD Global Investments LP | 7.48% | — | 224,135 | $10.4M |
| Skandinaviska Enskilda Banken AB (publ) | 0.04% | Add +19.8% | 213,891 | $10.0M |
| Schroder Investment Management Group | 0.01% | Add +114.7% | 187,433 | $8.9M |
| TD Asset Management Inc | 0.01% | Reduce -6.4% | 190,478 | $8.9M |
| Segall Bryant & Hamill, LLC | 0.12% | Add +4.8% | 189,477 | $8.8M |
| Barclays PLC | 0.00% | Add +1.3% | 185,677 | $8.6M |
| Neuberger Berman Group LLC | 0.01% | Add +171.3% | 182,188 | $8.5M |
| Swiss National Bank | 0.00% | Add +2.3% | 176,500 | $8.2M |
| Rice Hall James & Associates, LLC | 0.44% | Reduce -1.3% | 171,830 | $8.0M |
| Invesco Ltd. | 0.00% | Add +76.8% | 158,089 | $7.4M |
| Manufacturers Life Insurance Company, The | 0.01% | Add +0.5% | 148,489 | $7.0M |
| New York State Common Retirement Fund | 0.01% | Reduce -1.4% | 146,123 | $6.8M |
| Silvercrest Asset Management Group LLC | 0.05% | New | 144,239 | $6.7M |
| Wells Fargo & Company | 0.00% | Add +41.3% | 139,461 | $6.5M |
| Victory Capital Management Inc. | 0.00% | Reduce -40.6% | 138,685 | $6.5M |
| Envestnet Asset Management Inc. | 0.00% | Add +147.5% | 130,363 | $6.1M |
| Sio Capital Management, LLC | 0.96% | Reduce -28.6% | 124,841 | $5.8M |
| Russell Investments Group, Ltd. | 0.01% | Reduce -19.5% | 119,905 | $5.6M |
| Rhumbline Advisers | 0.00% | Reduce -12.0% | 115,752 | $5.4M |
| Sector Gamma As | 1.22% | New | 115,000 | $5.4M |
| Moody Aldrich Partners LLC | 0.96% | Reduce -4.4% | 110,415 | $5.1M |
| Connor, Clark & Lunn Investment Management Ltd. | 0.01% | Add +701.7% | 100,567 | $4.7M |
| AWM Investment Company, Inc. | 0.45% | No change | 100,000 | $4.7M |
| Alliancebernstein L.P. | 0.00% | No change | 93,020 | $4.3M |
| Decheng Capital LLC | 0.58% | Reduce -35.2% | 92,700 | $4.3M |
| Legal & General Group Plc | 0.00% | Reduce -6.4% | 87,802 | $4.1M |
| California State Teachers Retirement System | 0.00% | Add +1.6% | 85,568 | $4.0M |
| Alps Advisors Inc. | 0.02% | Add +64.0% | 77,765 | $3.6M |
| Affinity Asset Advisors, LLC | 0.26% | No change | 75,000 | $3.5M |
| Sei Investments Co. | 0.00% | Add +19.4% | 72,045 | $3.4M |
| Castleark Management LLC | 0.09% | New | 62,790 | $2.9M |
| Man Group plc | 0.01% | New | 62,560 | $2.9M |
| T. Rowe Price Investment Management, Inc. | 0.00% | Reduce -2.4% | 59,121 | $2.8M |
| State of Wisconsin Investment Board | 0.01% | Reduce -2.6% | 55,561 | $2.6M |
| Phocas Financial Corp. | 0.33% | Reduce -0.3% | 53,877 | $2.5M |
| MetLife Investment Management, LLC | 0.01% | Reduce -6.7% | 49,818 | $2.3M |
| Two Sigma Investments, LP | 0.00% | No change | 49,699 | $2.3M |
| Creative Planning | 0.00% | Add +16.6% | 47,321 | $2.2M |
| Royal Bank of Canada | 0.00% | Reduce -72.3% | 47,295 | $2.2M |
| Vestmark Advisory Solutions, Inc. | 0.03% | New | 46,552 | $2.2M |
| Lisanti Capital Growth, LLC | 0.47% | Add +88.0% | 43,040 | $2.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -0.0% | 42,002 | $2.0M |
| Susquehanna International Group, LLP | 0.00% | Reduce -87.0% | 33,511 | $1.6M |
| Raymond James Financial Inc. | 0.00% | New | 33,354 | $1.6M |
| First Trust Advisors LP | 0.00% | Add +378.3% | 33,150 | $1.5M |
| State of New Jersey Common Pension Fund D | 0.01% | Reduce -57.8% | 30,537 | $1.4M |
| Orion Porfolio Solutions, LLC | 0.01% | Add +80.8% | 30,495 | $1.4M |
| Intech Investment Management LLC | 0.01% | Add +36.1% | 30,243 | $1.4M |
| Handelsbanken Fonder AB | 0.00% | Reduce -8.1% | 29,500 | $1.4M |
| WINTON GROUP Ltd | 0.05% | Reduce -58.4% | 28,384 | $1.3M |
| BNP Paribas Financial Markets | 0.00% | Add +14.9% | 27,533 | $1.3M |
| Teachers Retirement System of the State of Kentucky | 0.01% | No change | 27,377 | $1.3M |
| Lewis Asset Management, LLC | 0.49% | Reduce -12.0% | 26,105 | $1.2M |
| Pathstone Holdings, LLC | 0.00% | Add +9.6% | 25,062 | $1.2M |
| Arizona State Retirement System | 0.01% | Reduce -4.9% | 25,014 | $1.2M |
| Police & Firemen's Retirement System of New Jersey | 0.01% | Reduce -0.8% | 24,820 | $1.2M |
| Progeny 3, Inc. | 0.06% | New | 24,000 | $1.1M |
| Headlands Technologies LLC | 0.09% | Add +14.8% | 23,217 | $1.1M |
| Parkman Healthcare Partners LLC | 0.10% | Reduce -69.0% | 22,852 | $1.1M |
| SG Americas Securities, LLC | 0.00% | Reduce -32.5% | 21,789 | $1.0M |
| HighMark Wealth Management LLC | 0.41% | Add +7.5% | 21,495 | $1.0M |
| Stifel Financial Corp. | 0.00% | Reduce -2.5% | 21,200 | $987K |
| ProShare Advisors LLC | 0.00% | Add +10.2% | 20,721 | $965K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +7.9% | 20,116 | $936K |
| Natixis Advisors, LLC | 0.00% | Reduce -61.3% | 20,035 | $933K |
| KLP Kapitalforvaltning As | 0.00% | Add +1.6% | 19,100 | $889K |
| Cerity Partners LLC | 0.00% | New | 18,974 | $883K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 18,406 | $857K |
| Assetmark, Inc. | 0.00% | Reduce -4.6% | 17,965 | $836K |
| Oppenheimer Asset Management Inc. | 0.01% | Add +235.8% | 17,786 | $828K |
| Franklin Resources Inc. | 0.00% | Reduce -13.4% | 17,671 | $823K |
| Glenmede Trust Co. NA | 0.00% | — | 16,944 | $789K |
| Citigroup Inc. | 0.00% | Reduce -21.4% | 16,337 | $760K |
| DNB Asset Management AS | 0.00% | Add +75.7% | 16,089 | $749K |
| Legato Capital Management LLC | 0.06% | Add +182.1% | 16,035 | $746K |
| Cresset Asset Management, LLC | 0.00% | Add +6.5% | 15,858 | $738K |
| Odyssean, LLC | 0.53% | — | 15,848 | $738K |
| AlphaQuest LLC | 0.04% | Add +7.7% | 15,844 | $738K |
| China Universal Asset Management Co., Ltd. | 0.06% | Reduce -6.3% | 15,463 | $720K |
| Virtus Investment Advisers, LLC | 0.17% | Add +282.7% | 13,535 | $630K |
| Teacher Retirement System of Texas | 0.00% | Reduce -39.3% | 13,219 | $615K |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 11,300 | $546K |
| PSP Research LLC | 0.46% | — | 11,316 | $527K |
| Los Angeles Capital Management LLC | 0.00% | Add +19.4% | 11,267 | $488K |
| Truist Financial Corp. | 0.00% | New | 9,879 | $460K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 9,008 | $419K |
| Fiduciary Trust Co | 0.00% | Add +19.9% | 8,897 | $414K |
| Quantinno Capital Management LP | 0.00% | Add +13.4% | 8,856 | $412K |
| Canada Pension Plan Investment Board | 0.00% | New | 8,829 | $411K |
| Tema ETFs LLC | 0.03% | Reduce -60.7% | 8,767 | $408K |
| NEOS Investment Management LLC | 0.00% | Reduce -60.7% | 8,767 | $408K |
| Baader Bank Aktiengesellschaft | 0.03% | New | 8,625 | $399K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Add +13.9% | 8,524 | $397K |
| CANADA LIFE ASSURANCE Co | 0.00% | Reduce -63.6% | 8,214 | $382K |
| Commerce Bank | 0.00% | Add +5.9% | 8,019 | $373K |
| Ameritas Investment Partners, Inc. | 0.01% | Reduce -2.9% | 7,340 | $342K |
| Xponance LLC | 0.00% | Add +1.4% | 7,195 | $335K |
| Park Avenue Securities LLC | 0.00% | New | 7,040 | $328K |
| Profund Advisors LLC | 0.01% | Reduce -31.1% | 6,950 | $324K |
| Rwa Wealth Partners, LLC | 0.00% | Add +20.2% | 6,846 | $319K |
| Advisors Asset Management, Inc. | 0.01% | Reduce -1.3% | 6,569 | $306K |
| LPL Financial LLC | 0.00% | New | 6,154 | $286K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +114.1% | 6,123 | $285K |
| Brooklyn Investment Group | 0.01% | New | 5,890 | $280K |
| Cibc World Markets Corp. | 0.00% | — | 5,982 | $278K |
| Oppenheimer & Co. Inc. | 0.00% | Add +14.9% | 5,973 | $278K |
| Palumbo Wealth Management LLC | 0.07% | New | 5,805 | $270K |
| Praxis Investment Management Inc. | 0.02% | No change | 5,805 | $270K |
| Mackenzie Financial Corp. | 0.00% | Reduce -4.6% | 5,666 | $268K |
| Amundi | 0.00% | New | 5,622 | $262K |
| Prudential Financial Inc. | 0.00% | Reduce -51.7% | 5,615 | $261K |
| US Bancorp \de | 0.00% | Add +7.9% | 5,511 | $257K |
| MML Investors Services, LLC | 0.00% | New | 5,394 | $251K |
| Keybank National Association | 0.00% | Reduce -34.1% | 5,357 | $249K |
| Principal Financial Group Inc. | 0.00% | Reduce -22.9% | 5,341 | $249K |
| STRS Ohio | 0.00% | Add +341.7% | 5,300 | $247K |
| PNC Financial Services Group, Inc. | 0.00% | Reduce -11.5% | 5,270 | $245K |
| Atria Investments, Inc | 0.00% | Add +1.0% | 5,139 | $239K |
| Callan Family Office, LLC | 0.01% | New | 5,002 | $233K |
| Walleye Capital LLC | 0.00% | New | 4,931 | $230K |
| Rafferty Asset Management, LLC | 0.00% | Reduce -21.3% | 4,865 | $226K |
| Cetera Investment Advisers | 0.00% | New | 4,810 | $224K |
| Arrowpoint Investment Partners (Singapore) Pte. Ltd. | 0.03% | New | 4,717 | $220K |
| Rockefeller Capital Management L.P. | 0.00% | Add +12.5% | 4,679 | $218K |
| Snowden Capital Advisors LLC | 0.01% | Reduce -4.3% | 4,668 | $217K |
| Meeder Advisory Services, Inc. | 0.01% | New | 4,646 | $216K |
| OneDigital Investment Advisors LLC | 0.00% | New | 4,622 | $215K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +26.6% | 4,611 | $215K |
| Bellevue Group AG | 0.00% | New | 4,040 | $188K |
| Comerica Bank | 0.00% | Add +420.1% | 3,396 | $158K |
| Nisa Investment Advisors, LLC | 0.00% | Add +0.1% | 3,202 | $149K |
| Bessemer Group Inc. | 0.00% | Add +0.3% | 3,111 | $145K |
| KBC Group NV | 0.00% | No change | 3,064 | $143K |
| Kestra Advisory Services, LLC | 0.00% | New | 2,922 | $136K |
| Amalgamated Bank | 0.00% | Reduce -3.0% | 2,841 | $132K |
| GF Fund Management Co. LTD. | 0.00% | Reduce -8.0% | 1,864 | $87K |
| Osaic Holdings, Inc. | 0.00% | Reduce -30.4% | 1,756 | $82K |
| Arax Advisory Partners | 0.00% | Add +131.2% | 1,498 | $70K |
| IFP Advisors, Inc | 0.00% | No change | 1,446 | $67K |
| Parallel Advisors, LLC | 0.00% | Add +34.6% | 1,225 | $57K |
| State of Wyoming | 0.00% | Reduce -31.4% | 669 | $31K |
| Smartleaf Asset Management LLC | 0.00% | Add +107.5% | 639 | $30K |
| Huntington National Bank | 0.00% | Add +4.0% | 619 | $29K |
| Sterling Capital Management LLC | 0.00% | Add +171.7% | 595 | $28K |
| Signaturefd, LLC | 0.00% | Add +32.5% | 514 | $24K |
| GAMMA Investing LLC | 0.00% | Add +97.4% | 460 | $21K |
| Farther Finance Advisors, LLC | 0.00% | Reduce -46.8% | 448 | $21K |
| Wellington-Altus USA Inc. | 0.01% | — | 395 | $18K |
| Larson Financial Group LLC | 0.00% | Add +354.7% | 291 | $14K |
| Daiwa Securities Group Inc. | 0.00% | Reduce -7.2% | 282 | $13K |
| Allworth Financial LP | 0.00% | Add +14.6% | 252 | $12K |
| Kemnay Advisory Services Inc. | 0.00% | New | 234 | $11K |
| Quadrant Capital Group LLC | 0.00% | No change | 230 | $11K |
| MAI Capital Management | 0.00% | New | 215 | $10K |
| SBI Securities Co., Ltd. | 0.00% | New | 210 | $10K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -22.1% | 201 | $9K |
| Cwm, LLC | 0.00% | Add +101.2% | 173 | $8K |
| Optiver Holding B.V. | 0.00% | Reduce -37.6% | 166 | $8K |
| Basecamp Wealth Advisors LLC | 0.00% | — | 163 | $8K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 158 | $7K |
| ORG Partners LLC | 0.00% | Add +440.7% | 146 | $7K |
| J.Safra Asset Management Corp | 0.00% | Add +21.9% | 117 | $5K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +64.2% | 110 | $5K |
| SageView Advisory Group, LLC | 0.00% | New | 110 | $5K |
| Versant Capital Management, Inc | 0.00% | No change | 104 | $5K |
| Rothschild Investment LLC | 0.00% | No change | 100 | $5K |
| Danske Bank A/S | 0.00% | No change | 100 | $5K |
| Parkside Financial Bank & Trust | 0.00% | Add +33.3% | 60 | $3K |
| Jones Financial Companies LLLP | 0.00% | New | 58 | $3K |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | New | 55 | $3K |
| Meeder Asset Management Inc. | 0.00% | Reduce -58.5% | 49 | $2K |
| Bare Financial Services, Inc | 0.00% | New | 47 | $2K |
| Cornerstone Planning Group LLC | 0.00% | No change | 42 | $2K |
| Motiv8 Investments LLC | 0.00% | New | 35 | $2K |
| Cornerstone Financial Management LLC | 0.00% | — | 34 | $2K |
| Cape Investment Advisory, Inc. | 0.00% | No change | 31 | $1K |
| Quarry LP | 0.00% | New | 30 | $1K |
| Whittier Trust Co. of Nevada Inc. | 0.00% | No change | 30 | $1K |
| Torren Management, LLC | 0.00% | — | 23 | $1K |
| Zions Bancorporation, National Association | 0.00% | New | 22 | $1K |
| Park Place Capital Corp | 0.00% | No change | 18 | $838 |
| Bell Investment Advisors, Inc | 0.00% | Reduce -37.0% | 17 | $792 |
| Physician Wealth Advisors, Inc. | 0.00% | Reduce -31.8% | 15 | $699 |
| CoreCap Advisors, LLC | 0.00% | New | 14 | $652 |
| Ares Financial Consulting, LLC | 0.00% | — | 12 | $559 |
| True Wealth Design, LLC | 0.00% | No change | 8 | $373 |
| Keating Financial Advisory Services, Inc. | 0.00% | — | 4 | $186 |
| Dunhill Financial, LLC | 0.00% | New | 2 | $79 |
| Inspire Investing, LLC | 0.00% | New | 1 | $29 |
| Covestor Ltd | 0.00% | Reduce -99.7% | 5 | $0 |
"% of holder's portfolio" is CRNX's weight in each manager's 13F, not the share of Crinetics Pharmaceuticals Inc. the manager owns.