Definium TherapeuticsDFTX
13F holders, Q1 2026 (March 31)246holders +238
62new positions
1sold out
5famous investors
$18.89avg. 13F price*
At the end of Q1 2026, 246 institutions reported holding Definium Therapeutics Inc. (DFTX) in their 13F filings, up 238 from Q4 2025. 62 opened new positions and 1 sold out. The largest holders were BlackRock, Inc. ($160.3M), Driehaus Capital Management LLC ($111.7M) and Avoro Capital Advisors LLC ($94.5M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Definium Therapeutics Inc.
- CUSIP
- 24477V105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 62 | $155.2M |
| Exits | 1 | $411K |
All 13F filers, Q4 2025 → Q1 2026: 19,658,272 shares bought and 8,325,956 shares sold, net +11,332,316 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 246 holders
| BlackRock, Inc. | 0.00% | Add +2.5% | 8,480,230 | $160.3M |
| Driehaus Capital Management LLC | 0.82% | Reduce -9.6% | 5,911,889 | $111.7M |
| Avoro Capital Advisors LLC | 0.93% | No change | 5,000,000 | $94.5M |
| Janus Henderson Group PLC | 0.03% | Add +47.5% | 3,556,041 | $67.2M |
| Deep Track Capital, LP | 1.17% | Add +78.9% | 3,000,000 | $56.7M |
| Geode Capital Management, LLC | 0.00% | Add +7.0% | 2,495,399 | $47.2M |
| State Street Corp. | 0.00% | Add +4.4% | 2,471,873 | $46.7M |
| Octagon Capital Advisors LP | 5.10% | Add +9.4% | 2,440,000 | $46.1M |
| Commodore Capital LP | 2.19% | No change | 2,000,000 | $37.8M |
| FMR LLC | 0.00% | Add +1016.7% | 1,809,610 | $34.2M |
| Trails Edge Capital Partners, LP | 7.73% | Reduce -32.3% | 1,738,110 | $32.9M |
| Goldman Sachs Group Inc. | 0.00% | Add +81.1% | 1,675,411 | $31.7M |
| ArrowMark Colorado Holdings LLC | 0.80% | New | 1,594,717 | $30.1M |
| Citadel Advisors | 0.02% | Add +535.1% | 1,333,442 | $25.2M |
| Wellington Management Group LLP | 0.00% | Add +6.9% | 1,304,749 | $24.7M |
| Candriam S.C.A. | 0.13% | Add +33.2% | 1,293,629 | $24.4M |
| Balyasny Asset Management L.P. | 0.05% | Reduce -2.6% | 1,274,221 | $24.1M |
| Two Sigma Investments, LP | 0.02% | Add +182.6% | 1,201,610 | $22.7M |
| Marshall Wace, LLP | 0.02% | Reduce -59.6% | 1,200,825 | $22.7M |
| Adage Capital Partners Gp, L.L.C. | 0.03% | No change | 1,150,000 | $21.7M |
| Vanguard Capital Management LLC | 0.00% | — | 1,096,978 | $20.7M |
| Holocene Advisors, LP | 0.05% | New | 1,091,967 | $20.6M |
| AWM Investment Company, Inc. | 2.25% | Reduce -22.6% | 1,076,893 | $20.4M |
| Catalio Capital Management, LP | 4.10% | New | 1,037,984 | $19.6M |
| Ameriprise Financial Inc. | 0.00% | Add +91.7% | 966,608 | $18.3M |
| Siren, L.L.C. | 0.48% | Add +14.9% | 919,493 | $17.4M |
| Vanguard Portfolio Management LLC | 0.00% | — | 872,665 | $16.5M |
| Millennium Management | 0.01% | Reduce -38.8% | 846,896 | $16.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.2% | 808,715 | $15.3M |
| Orbimed Advisors LLC | 0.34% | Reduce -34.5% | 804,000 | $15.2M |
| Northern Trust Corp. | 0.00% | Add +8.8% | 798,987 | $15.1M |
| Bank of New York Mellon Corp | 0.00% | Add +152.1% | 752,922 | $14.2M |
| Woodline Partners LP | 0.05% | Add +400.0% | 752,792 | $14.2M |
| Nuveen, LLC | 0.00% | Add +152.5% | 698,130 | $13.2M |
| Eventide Asset Management, LLC | 0.21% | New | 686,162 | $13.0M |
| Boxer Capital Management, LLC | 1.49% | No change | 598,500 | $11.3M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 575,937 | $10.9M |
| Ensign Peak Advisors, Inc | 0.02% | Add +108.7% | 546,783 | $10.3M |
| Blackstone Inc. | 0.04% | Reduce -75.3% | 508,668 | $9.6M |
| UBS Group AG | 0.00% | Reduce -27.8% | 493,977 | $9.3M |
| Morgan Stanley | 0.00% | Add +19.6% | 438,573 | $8.3M |
| Qube Research & Technologies Ltd | 0.01% | New | 426,055 | $8.1M |
| Deutsche Bank AG | 0.00% | Add +3.4% | 411,834 | $7.8M |
| Integral Health Asset Management, LLC | 0.40% | Add +14.3% | 400,000 | $7.6M |
| Tri Locum Partners LP | 0.98% | New | 369,588 | $7.0M |
| Superstring Capital Management LP | 4.75% | Reduce -17.3% | 351,461 | $6.6M |
| Sofinnova Investments, Inc. | 0.33% | New | 344,166 | $6.5M |
| Patient Square Capital LP | 1.11% | New | 331,000 | $6.3M |
| Stempoint Capital LP | 1.18% | New | 325,483 | $6.2M |
| RTW Investments, LP | 0.06% | No change | 300,000 | $5.7M |
| BIT Capital GmbH | 0.29% | New | 277,511 | $5.2M |
| D. E. Shaw & Co. | 0.00% | Reduce -7.5% | 271,717 | $5.1M |
| Jane Street Group, LLC | 0.01% | Reduce -51.5% | 260,241 | $4.9M |
| JPMorgan Chase & Co. | 0.00% | Add +72.1% | 264,545 | $4.6M |
| Royce & Associates LP | 0.04% | Add +42.7% | 234,051 | $4.4M |
| Seven Grand Managers, LLC | 0.28% | No change | 225,000 | $4.3M |
| Brevan Howard Capital Management LP | 0.04% | Add +1802.9% | 211,488 | $4.0M |
| PFM Health Sciences, LP | 0.42% | New | 205,317 | $3.9M |
| Tetragon Partners GP Ltd | 0.74% | New | 199,994 | $3.8M |
| HighVista Strategies LLC | 0.97% | New | 185,856 | $3.5M |
| Point72 Asset Management | 0.01% | Reduce -2.7% | 175,490 | $3.3M |
| Eversept Partners, LP | 0.20% | New | 160,723 | $3.0M |
| Swiss National Bank | 0.00% | No change | 158,400 | $3.0M |
| Bank of America Corp. | 0.00% | Add +43.3% | 158,345 | $3.0M |
| Soviero Asset Management, LP | 1.49% | Reduce -6.7% | 140,000 | $2.6M |
| Neuberger Berman Group LLC | 0.00% | New | 133,369 | $2.5M |
| Squarepoint Ops LLC | 0.01% | Add +176.5% | 125,522 | $2.4M |
| Rosalind Advisors, Inc. | 0.97% | Reduce -83.3% | 125,000 | $2.4M |
| Rhumbline Advisers | 0.00% | Add +8.3% | 119,972 | $2.3M |
| Russell Investments Group, Ltd. | 0.00% | Add +1247.6% | 119,464 | $2.3M |
| ExodusPoint Capital Management, LP | 0.02% | Add +453.7% | 104,915 | $2.0M |
| Data Collective IV GP, LLC | 3.39% | No change | 100,350 | $1.9M |
| Burkehill Global Management, LP | 0.10% | No change | 100,000 | $1.9M |
| Seven Fleet Capital Management LP | 0.59% | New | 99,887 | $1.9M |
| Royal Bank of Canada | 0.00% | Add +3.8% | 97,192 | $1.8M |
| Fred Alger Management, LLC | 0.01% | New | 92,165 | $1.7M |
| Alliancebernstein L.P. | 0.00% | Add +22.5% | 91,703 | $1.7M |
| AdvisorShares Investments LLC | 0.31% | Reduce -11.2% | 91,301 | $1.7M |
| HRT Financial LP | 0.00% | Add +239.2% | 89,141 | $1.7M |
| Invesco Ltd. | 0.00% | Add +65.1% | 88,121 | $1.7M |
| Group One Trading LLC | 0.05% | New | 87,832 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Reduce -82.9% | 81,456 | $1.5M |
| LPL Financial LLC | 0.00% | Add +1.3% | 78,271 | $1.5M |
| T. Rowe Price Associates Inc. | 0.00% | Add +34.0% | 70,001 | $1.3M |
| Platinum Investment Management Ltd. | 0.33% | No change | 70,000 | $1.3M |
| Legal & General Group Plc | 0.00% | Reduce -10.7% | 59,799 | $1.1M |
| Ikarian Capital, LLC | 0.16% | No change | 58,803 | $1.1M |
| AQR Capital Management | 0.00% | Reduce -2.1% | 57,094 | $1.1M |
| Rockefeller Capital Management L.P. | 0.00% | Add +15628.2% | 55,206 | $1.0M |
| MetLife Investment Management, LLC | 0.01% | Add +3.2% | 54,261 | $1.0M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 54,018 | $1.0M |
| Blair William & Co. | 0.00% | New | 53,695 | $1.0M |
| Kestra Private Wealth Services, LLC | 0.01% | Add +0.9% | 50,588 | $956K |
| State of Wisconsin Investment Board | 0.00% | Reduce -14.0% | 50,420 | $953K |
| Nisa Investment Advisors, LLC | 0.00% | Add +1.1% | 48,903 | $924K |
| Vanguard Global Advisers, LLC | 0.00% | — | 48,044 | $908K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +5.6% | 46,193 | $873K |
| Allstate Corp. | 0.01% | New | 45,366 | $857K |
| CenterBook Partners LP | 0.04% | Reduce -69.2% | 42,829 | $809K |
| Twinbeech Capital LP | 0.08% | New | 42,100 | $796K |
| Simplex Trading, LLC | 0.02% | Reduce -14.7% | 41,156 | $778K |
| Scotia Capital Inc. | 0.00% | Reduce -18.4% | 40,548 | $766K |
| Wells Fargo & Company | 0.00% | Reduce -62.7% | 39,973 | $755K |
| Quantinno Capital Management LP | 0.00% | Add +1.6% | 39,958 | $755K |
| Jennison Associates LLC | 0.00% | Reduce -25.7% | 39,957 | $755K |
| Barclays PLC | 0.00% | Reduce -78.4% | 39,683 | $750K |
| Palumbo Wealth Management LLC | 0.18% | Reduce -2.7% | 37,966 | $718K |
| Caxton Associates LLP | 0.02% | Add +137.4% | 37,255 | $704K |
| Walleye Capital LLC | 0.00% | New | 35,485 | $671K |
| Mariner, LLC | 0.00% | Add +72.8% | 34,851 | $659K |
| PSP Research LLC | 0.47% | Reduce -0.1% | 34,800 | $658K |
| Caption Management, LLC | 0.03% | New | 33,758 | $638K |
| Cetera Investment Advisers | 0.00% | Add +91.7% | 31,824 | $601K |
| Rathbones Group PLC | 0.00% | No change | 30,200 | $571K |
| Engineers Gate Manager LP | 0.01% | New | 29,767 | $563K |
| New York State Common Retirement Fund | 0.00% | No change | 29,600 | $559K |
| Sei Investments Co. | 0.00% | Add +137.6% | 28,117 | $531K |
| State of New Jersey Common Pension Fund D | 0.00% | New | 27,441 | $519K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +8.6% | 27,361 | $517K |
| Kingswood Wealth Advisors, LLC | 0.02% | New | 26,591 | $503K |
| Citigroup Inc. | 0.00% | Reduce -36.1% | 26,486 | $501K |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -6.8% | 26,404 | $499K |
| Bay Rivers Group | 0.21% | Add +64.7% | 26,346 | $498K |
| Intech Investment Management LLC | 0.00% | Reduce -15.7% | 24,990 | $472K |
| Campbell & CO Investment Adviser LLC | 0.03% | New | 24,755 | $468K |
| Raymond James Financial Inc. | 0.00% | Add +12.3% | 23,713 | $448K |
| BNP Paribas Financial Markets | 0.00% | Add +4.3% | 23,356 | $441K |
| Arizona State Retirement System | 0.00% | Reduce -0.8% | 22,054 | $417K |
| Virtus Investment Advisers, LLC | 0.11% | Add +2.5% | 21,727 | $411K |
| Concurrent Investment Advisors, LLC | 0.00% | Add +4.3% | 21,285 | $402K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +38.0% | 20,868 | $394K |
| Vanguard Investments Australia, Ltd. | 0.00% | — | 20,467 | $387K |
| China Universal Asset Management Co., Ltd. | 0.03% | Add +25.8% | 20,192 | $382K |
| Marex Group Ltd | 0.00% | No change | 20,000 | $378K |
| STRS Ohio | 0.00% | New | 19,300 | $365K |
| ProShare Advisors LLC | 0.00% | Reduce -13.0% | 18,731 | $354K |
| HighTower Advisors, LLC | 0.00% | New | 18,559 | $351K |
| Gsa Capital Partners LLP | 0.02% | Reduce -65.3% | 18,155 | $343K |
| Sequoia Financial Advisors, LLC | 0.00% | Add +0.4% | 17,245 | $326K |
| Voya Investment Management LLC | 0.00% | Add +2.5% | 16,384 | $310K |
| Persistent Asset Partners Ltd | 0.12% | New | 15,861 | $300K |
| Virtu Financial LLC | 0.01% | New | 14,460 | $273K |
| Heritage Wealth Management, Inc. | 0.15% | New | 14,375 | $272K |
| Profund Advisors LLC | 0.01% | Reduce -35.4% | 14,196 | $268K |
| Amundi | 0.00% | New | 14,136 | $267K |
| Boothbay Fund Management, LLC | 0.01% | New | 14,096 | $266K |
| Fox Run Management, L.L.C. | 0.04% | Reduce -52.6% | 14,557 | $255K |
| Pictet Asset Management Holding SA | 0.00% | New | 13,295 | $251K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +1224.0% | 13,240 | $250K |
| Magnetar Financial LLC | 0.00% | New | 13,178 | $249K |
| Money Concepts Capital Corp. | 0.01% | No change | 13,000 | $246K |
| Summit Trail Advisors, LLC | 0.00% | New | 13,000 | $246K |
| Federation des caisses Desjardins du Quebec | 0.00% | Add +19.2% | 12,644 | $239K |
| Stifel Financial Corp. | 0.00% | New | 12,626 | $239K |
| Cinctive Capital Management LP | 0.02% | New | 12,551 | $237K |
| Twelve Points Wealth Management LLC | 0.05% | Add +15.0% | 12,245 | $231K |
| Bank of Montreal | 0.00% | Add +2.8% | 12,136 | $229K |
| Diversify Wealth Management, LLC | 0.00% | Add +10.0% | 11,000 | $225K |
| Sanctuary Advisors, LLC | 0.00% | Add +7.0% | 11,466 | $217K |
| Chicago Partners Investment Group LLC | 0.00% | New | 9,307 | $215K |
| RPS Advisory Solutions LLC | 0.12% | New | 11,355 | $215K |
| Dynamic Technology Lab Private Ltd | 0.03% | Reduce -52.6% | 10,880 | $206K |
| Osaic Holdings, Inc. | 0.00% | Add +0.3% | 10,559 | $200K |
| SG Americas Securities, LLC | 0.00% | New | 10,493 | $198K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -65.8% | 10,412 | $197K |
| Verition Fund Management LLC | 0.00% | Reduce -92.2% | 10,384 | $196K |
| Teacher Retirement System of Texas | 0.00% | Reduce -12.7% | 10,300 | $195K |
| Commonwealth Equity Services, LLC | 0.00% | Reduce -24.7% | 10,251 | $194K |
| Cibc World Market Inc. | 0.00% | New | 10,049 | $190K |
| Sharpepoint LLC | 0.11% | Reduce -1.3% | 10,000 | $189K |
| King Wealth Management Group | 0.02% | No change | 10,000 | $189K |
| Swiss Life Asset Management Ltd | 0.00% | New | 17,745 | $187K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 7,641 | $144K |
| PNC Financial Services Group, Inc. | 0.00% | Add +7.5% | 7,620 | $144K |
| North Star Investment Management Corp. | 0.01% | Add +13.0% | 7,571 | $143K |
| Hollencrest Capital Management | 0.01% | Reduce -1.7% | 7,386 | $140K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +68.5% | 7,305 | $138K |
| Cwm, LLC | 0.00% | Add +4.6% | 5,600 | $106K |
| Walleye Trading LLC | 0.00% | Add +27.2% | 5,414 | $102K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 5,200 | $98K |
| Caitong International Asset Management Co., Ltd | 0.01% | Add +26806.7% | 4,036 | $76K |
| Sound Income Strategies, LLC | 0.00% | No change | 3,690 | $76K |
| Fifth Third Bancorp | 0.00% | No change | 3,300 | $62K |
| Advisory Services Network, LLC | 0.00% | New | 2,659 | $50K |
| Sterling Capital Management LLC | 0.00% | Reduce -37.6% | 2,443 | $46K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +169.9% | 2,413 | $46K |
| GF Fund Management Co. LTD. | 0.00% | Add +14.4% | 2,213 | $42K |
| KBC Group NV | 0.00% | New | 2,172 | $41K |
| Crewe Advisors LLC | 0.00% | No change | 1,999 | $38K |
| TD Waterhouse Canada Inc. | 0.00% | Add +17.6% | 1,802 | $37K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | Add +31.4% | 1,812 | $34K |
| National Bank of Canada | 0.00% | Reduce -8.5% | 1,708 | $32K |
| High Note Wealth, LLC | 0.01% | No change | 1,500 | $28K |
| GAMMA Investing LLC | 0.00% | Add +7.9% | 1,111 | $21K |
| Opal Wealth Advisors, LLC | 0.00% | New | 1,101 | $21K |
| Stone House Investment Management, LLC | 0.00% | No change | 1,000 | $19K |
| Bullock Wealth Management Group | 0.01% | Reduce -24.0% | 907 | $19K |
| First Horizon Corp. | 0.00% | Add +14.1% | 962 | $18K |
| Kemnay Advisory Services Inc. | 0.00% | New | 806 | $15K |
| Farther Finance Advisors, LLC | 0.00% | Add +24.1% | 567 | $12K |
| Los Angeles Capital Management LLC | 0.00% | New | 618 | $12K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | No change | 568 | $11K |
| Harbour Investments, Inc. | 0.00% | New | 556 | $11K |
| Larson Financial Group LLC | 0.00% | No change | 535 | $10K |
| Arax Advisory Partners | 0.00% | Reduce -2.7% | 466 | $9K |
| Private Wealth Management Group, LLC | 0.00% | New | 450 | $9K |
| Nvwm, LLC | 0.00% | No change | 416 | $8K |
| Meeder Asset Management Inc. | 0.00% | New | 353 | $7K |
| Western Pacific Wealth Management, LP | 0.01% | New | 333 | $6K |
| EverSource Wealth Advisors, LLC | 0.00% | Add +16.1% | 295 | $6K |
| Rothschild Investment LLC | 0.00% | Add +1.7% | 292 | $6K |
| Ancora Advisors LLC | 0.00% | New | 251 | $5K |
| Parallel Advisors, LLC | 0.00% | No change | 232 | $4K |
| Federated Hermes, Inc. | 0.00% | Add +209.0% | 207 | $4K |
| Smartleaf Asset Management LLC | 0.00% | New | 215 | $4K |
| Atlantic Edge Private Wealth Management, LLC | 0.00% | No change | 193 | $4K |
| Jones Financial Companies LLLP | 0.00% | New | 180 | $3K |
| Strategic Wealth Partners, Ltd. | 0.00% | No change | 166 | $3K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -16.2% | 155 | $3K |
| Salem Investment Counselors Inc. | 0.00% | New | 150 | $3K |
| Sankala Group LLC | 0.00% | Reduce -63.9% | 141 | $3K |
| Allworth Financial LP | 0.00% | Reduce -14.2% | 127 | $2K |
| MAI Capital Management | 0.00% | Add +74.6% | 103 | $2K |
| HighMark Wealth Management LLC | 0.00% | No change | 100 | $2K |
| Lanark Financial, Inc. | 0.00% | No change | 100 | $2K |
| SBI Securities Co., Ltd. | 0.00% | Add +7.7% | 98 | $2K |
| MH & Associates Securities Management Corp. | 0.00% | No change | 66 | $1K |
| Activest Wealth Management | 0.00% | No change | 66 | $1K |
| Louisbourg Investments Inc. | 0.00% | New | 52 | $983 |
| Optiver Holding B.V. | 0.00% | Reduce -60.2% | 49 | $926 |
| Sunbelt Securities, Inc. | 0.00% | No change | 44 | $832 |
| Anfield Capital Management, LLC | 0.00% | New | 36 | $680 |
| Plante Moran Financial Advisors, LLC | 0.00% | No change | 36 | $680 |
| Financial Gravity Asset Management, Inc. | 0.00% | No change | 35 | $662 |
| RMG Wealth Management LLC | 0.00% | New | 30 | $642 |
| Chesapeake Asset Management LLC | 0.00% | No change | 33 | $623 |
| Benson Wealth Management INC | 0.00% | New | 30 | $567 |
| Robbins Farley | 0.00% | No change | 28 | $530 |
| Vanguard National Trust Co | 0.00% | — | 27 | $510 |
| Rachor Investment Advisory Services, LLC | 0.00% | No change | 25 | $473 |
| Pinnacle Wealth Planning Services, Inc. | 0.00% | No change | 25 | $472 |
| Essential Partners LLC | 0.00% | No change | 21 | $397 |
| NewEdge Advisors, LLC | 0.00% | Reduce -95.0% | 7 | $125 |
| CoreCap Advisors, LLC | 0.00% | No change | 5 | $95 |
| Keating Financial Advisory Services, Inc. | 0.00% | Reduce -85.7% | 1 | $19 |
| Tsfg, LLC | 0.00% | No change | 6 | $0 |
"% of holder's portfolio" is DFTX's weight in each manager's 13F, not the share of Definium Therapeutics Inc. the manager owns.