Denali TherapeuticsDNLI
13F holders, Q2 2025 (June 30)230holders +8
45new positions
37sold out
7famous investors
$13.99avg. 13F price*
At the end of Q2 2025, 230 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 8 from Q1 2025. 45 opened new positions and 37 sold out. The largest holders were BlackRock, Inc. ($168.6M), Baillie Gifford & Co. ($167.3M) and Vanguard Group Inc. ($165.2M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $116.5M |
| Exits | 37 | $31.1M |
All 13F filers, Q1 2025 → Q2 2025: 16,081,223 shares bought and 14,409,105 shares sold, net +1,672,118 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 230 holders
| BlackRock, Inc. | 0.00% | Reduce -12.9% | 12,053,345 | $168.6M |
| Baillie Gifford & Co. | 0.12% | Reduce -1.1% | 11,955,323 | $167.3M |
| Vanguard Group Inc. | 0.00% | Add +0.1% | 11,810,735 | $165.2M |
| FMR LLC | 0.01% | Add +1.7% | 7,538,468 | $105.5M |
| T. Rowe Price Associates Inc. | 0.01% | Add +50.7% | 6,582,295 | $92.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -7.5% | 6,262,277 | $87.6M |
| Wellington Management Group LLP | 0.01% | Reduce -50.4% | 5,664,733 | $79.2M |
| Temasek Holdings (Private) Ltd | 0.29% | No change | 5,355,832 | $74.9M |
| Capital Research Global Investors | 0.01% | Reduce -0.3% | 4,750,579 | $66.5M |
| State Street Corp. | 0.00% | Add +1.3% | 4,517,994 | $63.2M |
| Norges Bank | 0.01% | Add +29.5% | 3,947,387 | $55.2M |
| Crestline Management, L.P. | 86.33% | Reduce -7.2% | 3,860,732 | $54.0M |
| Baker Bros. Advisors LP | 0.51% | No change | 3,731,695 | $52.2M |
| T. Rowe Price Investment Management, Inc. | 0.03% | New | 3,246,934 | $45.4M |
| Geode Capital Management, LLC | 0.00% | Add +4.5% | 3,172,305 | $44.4M |
| Alliancebernstein L.P. | 0.01% | Reduce -0.6% | 3,137,140 | $43.9M |
| Dimensional Fund Advisors LP | 0.01% | Add +14.8% | 2,412,928 | $33.8M |
| Point72 Asset Management | 0.08% | New | 2,213,947 | $31.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +11.6% | 1,865,324 | $26.1M |
| Fisher Asset Management | 0.01% | Add +11.1% | 1,515,991 | $21.2M |
| Marshall Wace, LLP | 0.02% | Reduce -35.8% | 1,405,250 | $19.7M |
| Morgan Stanley | 0.00% | Add +4.7% | 1,312,016 | $18.4M |
| Citadel Advisors | 0.02% | Add +6.8% | 1,248,953 | $17.5M |
| Northern Trust Corp. | 0.00% | Add +6.1% | 1,201,709 | $16.8M |
| Principal Financial Group Inc. | 0.01% | Reduce -0.8% | 1,072,983 | $15.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.6% | 1,056,019 | $14.8M |
| UBS Group AG | 0.00% | Add +20.6% | 950,764 | $13.3M |
| Aberdeen Group plc | 0.02% | Add +18.8% | 902,751 | $12.6M |
| Millennium Management | 0.01% | Reduce -39.7% | 900,501 | $12.6M |
| Casdin Capital, LLC | 1.13% | Reduce -10.1% | 890,000 | $12.5M |
| Candriam S.C.A. | 0.07% | Reduce -1.6% | 844,249 | $11.8M |
| Siren, L.L.C. | 0.59% | No change | 821,513 | $11.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -28.4% | 790,756 | $11.1M |
| Voloridge Investment Management, LLC | 0.04% | Add +155.2% | 770,527 | $10.8M |
| Stempoint Capital LP | 3.19% | Add +6.1% | 707,915 | $9.9M |
| Bank of America Corp. | 0.00% | Add +45.2% | 650,222 | $9.1M |
| Cercano Management LLC | 0.25% | No change | 625,000 | $8.7M |
| Masters Capital Management LLC | 1.62% | New | 600,000 | $8.4M |
| Nuveen, LLC | 0.00% | Add +84.3% | 595,217 | $8.3M |
| Segall Bryant & Hamill, LLC | 0.10% | Add +78.0% | 500,559 | $7.0M |
| TD Asset Management Inc | 0.01% | Add +60.8% | 496,290 | $6.9M |
| Ensign Peak Advisors, Inc | 0.01% | Reduce -19.4% | 473,695 | $6.6M |
| Yiheng Capital Management, L.P. | 2.38% | No change | 469,981 | $6.6M |
| Barclays PLC | 0.00% | Add +77.0% | 425,981 | $6.0M |
| Pictet Asset Management Holding SA | 0.01% | Add +20.7% | 415,112 | $5.9M |
| Holocene Advisors, LP | 0.01% | New | 403,172 | $5.6M |
| Camber Capital Management LP | 0.78% | Reduce -68.0% | 400,000 | $5.6M |
| Cubist Systematic Strategies, LLC | 0.06% | New | 396,586 | $5.5M |
| Royal Bank of Canada | 0.00% | Add +2602.7% | 390,155 | $5.5M |
| Schroder Investment Management Group | 0.00% | Add +32.5% | 386,539 | $5.4M |
| Clarius Group, LLC | 0.30% | No change | 368,995 | $5.2M |
| Edgestream Partners, L.P. | 0.13% | New | 342,923 | $4.8M |
| American Century Companies Inc. | 0.00% | Reduce -8.9% | 318,193 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +22.1% | 315,102 | $4.4M |
| Pier Capital, LLC | 0.67% | Reduce -6.2% | 314,796 | $4.4M |
| AXA S.A. | 0.01% | Add +0.2% | 293,853 | $4.1M |
| Hudson Bay Capital Management LP | 0.03% | Add +16.0% | 290,000 | $4.1M |
| Marex Group Ltd | 0.07% | New | 262,000 | $3.7M |
| Swiss National Bank | 0.00% | No change | 250,900 | $3.5M |
| Palo Alto Investors LP | 0.71% | New | 239,809 | $3.4M |
| Invesco Ltd. | 0.00% | Add +16.0% | 219,795 | $3.1M |
| Rhumbline Advisers | 0.00% | Add +11.7% | 212,503 | $3.0M |
| Twinbeech Capital LP | 0.07% | Add +192.1% | 210,370 | $2.9M |
| Edmond DE Rothschild Holding S.A. | 0.05% | No change | 205,680 | $2.9M |
| SCS Capital Management LLC | 0.03% | No change | 197,998 | $2.8M |
| Renaissance Technologies | 0.00% | Add +13.1% | 195,700 | $2.7M |
| JPMorgan Chase & Co. | 0.00% | Add +1.7% | 191,613 | $2.7M |
| Soleus Capital Management, L.P. | 0.18% | Add +34.9% | 182,110 | $2.5M |
| Groupama Asset Managment | 0.04% | Add +21.5% | 175,531 | $2.5M |
| Teachers Retirement System of the State of Kentucky | 0.02% | Reduce -6.5% | 171,553 | $2.4M |
| DAFNA Capital Management LLC | 0.66% | Add +31.7% | 168,500 | $2.4M |
| Susquehanna International Group, LLP | 0.00% | Reduce -3.6% | 161,136 | $2.3M |
| Campbell & CO Investment Adviser LLC | 0.13% | Add +109.3% | 142,708 | $2.0M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +47.3% | 137,880 | $1.9M |
| Deutsche Bank AG | 0.00% | Reduce -13.0% | 135,969 | $1.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +52.2% | 134,703 | $1.9M |
| Legal & General Group Plc | 0.00% | Reduce -13.3% | 131,755 | $1.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -5.3% | 122,262 | $1.7M |
| California State Teachers Retirement System | 0.00% | Add +1.5% | 119,327 | $1.7M |
| Engineers Gate Manager LP | 0.02% | Add +575.1% | 116,101 | $1.6M |
| Woodline Partners LP | 0.01% | No change | 113,517 | $1.6M |
| Trexquant Investment LP | 0.02% | Reduce -3.5% | 109,242 | $1.5M |
| Ameriprise Financial Inc. | 0.00% | New | 102,033 | $1.4M |
| Rhenman & Partners Asset Management AB | 0.18% | No change | 100,000 | $1.4M |
| Savvy Advisors, Inc. | 0.09% | New | 97,793 | $1.4M |
| Integrated Wealth Concepts LLC | 0.01% | New | 96,046 | $1.3M |
| Polar Asset Management Partners Inc. | 0.04% | Add +337.2% | 91,600 | $1.3M |
| Wells Fargo & Company | 0.00% | Add +16.0% | 89,639 | $1.3M |
| Algert Global LLC | 0.03% | New | 85,840 | $1.2M |
| Jane Street Group, LLC | 0.00% | Reduce -60.1% | 85,332 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Reduce -0.3% | 79,627 | $1.1M |
| MetLife Investment Management, LLC | 0.01% | Add +5.8% | 79,075 | $1.1M |
| Alps Advisors Inc. | 0.01% | Reduce -29.6% | 78,356 | $1.1M |
| Citigroup Inc. | 0.00% | Reduce -60.7% | 76,315 | $1.1M |
| Intech Investment Management LLC | 0.01% | Reduce -7.4% | 71,866 | $1.0M |
| Man Group plc | 0.00% | Reduce -58.7% | 70,028 | $980K |
| Thrivent Financial for Lutherans | 0.00% | No change | 67,917 | $950K |
| TT International Asset Management LTD | 0.17% | New | 65,000 | $909K |
| Graham Capital Management, L.P. | 0.03% | Add +50.7% | 64,799 | $907K |
| Franklin Resources Inc. | 0.00% | Reduce -22.5% | 64,525 | $903K |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.