Denali TherapeuticsDNLI
13F holders, Q2 2025 (June 30)230holders +8
45new positions
37sold out
7famous investors
$13.99avg. 13F price*
At the end of Q2 2025, 230 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 8 from Q1 2025. 45 opened new positions and 37 sold out. The largest holders were BlackRock, Inc. ($168.6M), Baillie Gifford & Co. ($167.3M) and Vanguard Group Inc. ($165.2M). 7 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 45 | $116.5M |
| Exits | 37 | $31.1M |
All 13F filers, Q1 2025 → Q2 2025: 16,081,223 shares bought and 14,409,105 shares sold, net +1,672,118 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 230 holders
| BlackRock, Inc. | 0.00% | Reduce -12.9% | 12,053,345 | $168.6M |
| Baillie Gifford & Co. | 0.12% | Reduce -1.1% | 11,955,323 | $167.3M |
| Vanguard Group Inc. | 0.00% | Add +0.1% | 11,810,735 | $165.2M |
| FMR LLC | 0.01% | Add +1.7% | 7,538,468 | $105.5M |
| T. Rowe Price Associates Inc. | 0.01% | Add +50.7% | 6,582,295 | $92.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -7.5% | 6,262,277 | $87.6M |
| Wellington Management Group LLP | 0.01% | Reduce -50.4% | 5,664,733 | $79.2M |
| Temasek Holdings (Private) Ltd | 0.29% | No change | 5,355,832 | $74.9M |
| Capital Research Global Investors | 0.01% | Reduce -0.3% | 4,750,579 | $66.5M |
| State Street Corp. | 0.00% | Add +1.3% | 4,517,994 | $63.2M |
| Norges Bank | 0.01% | Add +29.5% | 3,947,387 | $55.2M |
| Crestline Management, L.P. | 86.33% | Reduce -7.2% | 3,860,732 | $54.0M |
| Baker Bros. Advisors LP | 0.51% | No change | 3,731,695 | $52.2M |
| T. Rowe Price Investment Management, Inc. | 0.03% | New | 3,246,934 | $45.4M |
| Geode Capital Management, LLC | 0.00% | Add +4.5% | 3,172,305 | $44.4M |
| Alliancebernstein L.P. | 0.01% | Reduce -0.6% | 3,137,140 | $43.9M |
| Dimensional Fund Advisors LP | 0.01% | Add +14.8% | 2,412,928 | $33.8M |
| Point72 Asset Management | 0.08% | New | 2,213,947 | $31.0M |
| Goldman Sachs Group Inc. | 0.00% | Add +11.6% | 1,865,324 | $26.1M |
| Fisher Asset Management | 0.01% | Add +11.1% | 1,515,991 | $21.2M |
| Marshall Wace, LLP | 0.02% | Reduce -35.8% | 1,405,250 | $19.7M |
| Morgan Stanley | 0.00% | Add +4.7% | 1,312,016 | $18.4M |
| Citadel Advisors | 0.02% | Add +6.8% | 1,248,953 | $17.5M |
| Northern Trust Corp. | 0.00% | Add +6.1% | 1,201,709 | $16.8M |
| Principal Financial Group Inc. | 0.01% | Reduce -0.8% | 1,072,983 | $15.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.6% | 1,056,019 | $14.8M |
| UBS Group AG | 0.00% | Add +20.6% | 950,764 | $13.3M |
| Aberdeen Group plc | 0.02% | Add +18.8% | 902,751 | $12.6M |
| Millennium Management | 0.01% | Reduce -39.7% | 900,501 | $12.6M |
| Casdin Capital, LLC | 1.13% | Reduce -10.1% | 890,000 | $12.5M |
| Candriam S.C.A. | 0.07% | Reduce -1.6% | 844,249 | $11.8M |
| Siren, L.L.C. | 0.59% | No change | 821,513 | $11.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -28.4% | 790,756 | $11.1M |
| Voloridge Investment Management, LLC | 0.04% | Add +155.2% | 770,527 | $10.8M |
| Stempoint Capital LP | 3.19% | Add +6.1% | 707,915 | $9.9M |
| Bank of America Corp. | 0.00% | Add +45.2% | 650,222 | $9.1M |
| Cercano Management LLC | 0.25% | No change | 625,000 | $8.7M |
| Masters Capital Management LLC | 1.62% | New | 600,000 | $8.4M |
| Nuveen, LLC | 0.00% | Add +84.3% | 595,217 | $8.3M |
| Segall Bryant & Hamill, LLC | 0.10% | Add +78.0% | 500,559 | $7.0M |
| TD Asset Management Inc | 0.01% | Add +60.8% | 496,290 | $6.9M |
| Ensign Peak Advisors, Inc | 0.01% | Reduce -19.4% | 473,695 | $6.6M |
| Yiheng Capital Management, L.P. | 2.38% | No change | 469,981 | $6.6M |
| Barclays PLC | 0.00% | Add +77.0% | 425,981 | $6.0M |
| Pictet Asset Management Holding SA | 0.01% | Add +20.7% | 415,112 | $5.9M |
| Holocene Advisors, LP | 0.01% | New | 403,172 | $5.6M |
| Camber Capital Management LP | 0.78% | Reduce -68.0% | 400,000 | $5.6M |
| Cubist Systematic Strategies, LLC | 0.06% | New | 396,586 | $5.5M |
| Royal Bank of Canada | 0.00% | Add +2602.7% | 390,155 | $5.5M |
| Schroder Investment Management Group | 0.00% | Add +32.5% | 386,539 | $5.4M |
| Clarius Group, LLC | 0.30% | No change | 368,995 | $5.2M |
| Edgestream Partners, L.P. | 0.13% | New | 342,923 | $4.8M |
| American Century Companies Inc. | 0.00% | Reduce -8.9% | 318,193 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +22.1% | 315,102 | $4.4M |
| Pier Capital, LLC | 0.67% | Reduce -6.2% | 314,796 | $4.4M |
| AXA S.A. | 0.01% | Add +0.2% | 293,853 | $4.1M |
| Hudson Bay Capital Management LP | 0.03% | Add +16.0% | 290,000 | $4.1M |
| Marex Group Ltd | 0.07% | New | 262,000 | $3.7M |
| Swiss National Bank | 0.00% | No change | 250,900 | $3.5M |
| Palo Alto Investors LP | 0.71% | New | 239,809 | $3.4M |
| Invesco Ltd. | 0.00% | Add +16.0% | 219,795 | $3.1M |
| Rhumbline Advisers | 0.00% | Add +11.7% | 212,503 | $3.0M |
| Twinbeech Capital LP | 0.07% | Add +192.1% | 210,370 | $2.9M |
| Edmond DE Rothschild Holding S.A. | 0.05% | No change | 205,680 | $2.9M |
| SCS Capital Management LLC | 0.03% | No change | 197,998 | $2.8M |
| Renaissance Technologies | 0.00% | Add +13.1% | 195,700 | $2.7M |
| JPMorgan Chase & Co. | 0.00% | Add +1.7% | 191,613 | $2.7M |
| Soleus Capital Management, L.P. | 0.18% | Add +34.9% | 182,110 | $2.5M |
| Groupama Asset Managment | 0.04% | Add +21.5% | 175,531 | $2.5M |
| Teachers Retirement System of the State of Kentucky | 0.02% | Reduce -6.5% | 171,553 | $2.4M |
| DAFNA Capital Management LLC | 0.66% | Add +31.7% | 168,500 | $2.4M |
| Susquehanna International Group, LLP | 0.00% | Reduce -3.6% | 161,136 | $2.3M |
| Campbell & CO Investment Adviser LLC | 0.13% | Add +109.3% | 142,708 | $2.0M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +47.3% | 137,880 | $1.9M |
| Deutsche Bank AG | 0.00% | Reduce -13.0% | 135,969 | $1.9M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +52.2% | 134,703 | $1.9M |
| Legal & General Group Plc | 0.00% | Reduce -13.3% | 131,755 | $1.8M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -5.3% | 122,262 | $1.7M |
| California State Teachers Retirement System | 0.00% | Add +1.5% | 119,327 | $1.7M |
| Engineers Gate Manager LP | 0.02% | Add +575.1% | 116,101 | $1.6M |
| Woodline Partners LP | 0.01% | No change | 113,517 | $1.6M |
| Trexquant Investment LP | 0.02% | Reduce -3.5% | 109,242 | $1.5M |
| Ameriprise Financial Inc. | 0.00% | New | 102,033 | $1.4M |
| Rhenman & Partners Asset Management AB | 0.18% | No change | 100,000 | $1.4M |
| Savvy Advisors, Inc. | 0.09% | New | 97,793 | $1.4M |
| Integrated Wealth Concepts LLC | 0.01% | New | 96,046 | $1.3M |
| Polar Asset Management Partners Inc. | 0.04% | Add +337.2% | 91,600 | $1.3M |
| Wells Fargo & Company | 0.00% | Add +16.0% | 89,639 | $1.3M |
| Algert Global LLC | 0.03% | New | 85,840 | $1.2M |
| Jane Street Group, LLC | 0.00% | Reduce -60.1% | 85,332 | $1.2M |
| State of Wisconsin Investment Board | 0.00% | Reduce -0.3% | 79,627 | $1.1M |
| MetLife Investment Management, LLC | 0.01% | Add +5.8% | 79,075 | $1.1M |
| Alps Advisors Inc. | 0.01% | Reduce -29.6% | 78,356 | $1.1M |
| Citigroup Inc. | 0.00% | Reduce -60.7% | 76,315 | $1.1M |
| Intech Investment Management LLC | 0.01% | Reduce -7.4% | 71,866 | $1.0M |
| Man Group plc | 0.00% | Reduce -58.7% | 70,028 | $980K |
| Thrivent Financial for Lutherans | 0.00% | No change | 67,917 | $950K |
| TT International Asset Management LTD | 0.17% | New | 65,000 | $909K |
| Graham Capital Management, L.P. | 0.03% | Add +50.7% | 64,799 | $907K |
| Franklin Resources Inc. | 0.00% | Reduce -22.5% | 64,525 | $903K |
| DekaBank Deutsche Girozentrale | 0.00% | Reduce -6.9% | 59,800 | $841K |
| Janus Henderson Group PLC | 0.00% | No change | 60,028 | $839K |
| Creative Planning | 0.00% | Add +88.7% | 57,678 | $807K |
| Pier 88 Investment Partners LLC | 0.85% | Add +27.3% | 57,150 | $800K |
| Tudor Investment Corporation | 0.01% | Reduce -23.6% | 55,448 | $776K |
| Ironwood Investment Management LLC | 0.36% | Add +7.9% | 53,212 | $744K |
| Guggenheim Capital LLC | 0.01% | Reduce -7.4% | 51,860 | $726K |
| Verition Fund Management LLC | 0.00% | Add +270.1% | 50,809 | $711K |
| MAI Capital Management | 0.00% | No change | 46,526 | $651K |
| Victory Capital Management Inc. | 0.00% | Add +9.6% | 45,616 | $638K |
| Pathstone Holdings, LLC | 0.00% | Add +17.6% | 45,040 | $630K |
| Employees Retirement System of Texas | 0.01% | No change | 43,769 | $612K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +9.6% | 43,587 | $610K |
| Skandinaviska Enskilda Banken AB (publ) | 0.00% | No change | 43,245 | $605K |
| Knights of Columbus Asset Advisors LLC | 0.03% | Reduce -4.5% | 38,479 | $538K |
| New York State Common Retirement Fund | 0.00% | Reduce -45.2% | 38,478 | $538K |
| Handelsbanken Fonder AB | 0.00% | No change | 38,300 | $536K |
| Arizona State Retirement System | 0.00% | Add +2.7% | 38,114 | $533K |
| Voya Investment Management LLC | 0.00% | Reduce -29.6% | 35,908 | $502K |
| ADAR1 Capital Management, LLC | 0.08% | Add +157.4% | 35,716 | $500K |
| Dana Investment Advisors, Inc. | 0.02% | Add +10.6% | 35,561 | $497K |
| Teacher Retirement System of Texas | 0.00% | Add +1.0% | 35,221 | $493K |
| State Board of Administration of Florida Retirement System | 0.00% | No change | 34,168 | $478K |
| Envestnet Asset Management Inc. | 0.00% | Add +6.7% | 33,538 | $469K |
| ProShare Advisors LLC | 0.00% | Reduce -2.6% | 32,582 | $456K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | Add +14.8% | 30,394 | $425K |
| China Universal Asset Management Co., Ltd. | 0.04% | Add +0.2% | 29,178 | $408K |
| Dark Forest Capital Management LP | 0.02% | Reduce -64.8% | 28,433 | $398K |
| Two Sigma Advisers, LP | 0.00% | Reduce -21.8% | 27,600 | $386K |
| Erste Asset Management GmbH | 0.00% | No change | 26,900 | $379K |
| Profund Advisors LLC | 0.01% | Reduce -4.1% | 26,723 | $374K |
| Raymond James Financial Inc. | 0.00% | Add +2.5% | 26,596 | $372K |
| KLP Kapitalforvaltning As | 0.00% | No change | 26,100 | $365K |
| Cinctive Capital Management LP | 0.02% | New | 24,310 | $340K |
| AlphaQuest LLC | 0.03% | Reduce -8.4% | 22,964 | $321K |
| HighTower Advisors, LLC | 0.00% | Reduce -4.5% | 22,533 | $315K |
| Capital Fund Management S.A. | 0.00% | New | 21,871 | $306K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +14.9% | 21,484 | $301K |
| AQR Capital Management | 0.00% | New | 21,217 | $297K |
| Two Sigma Investments, LP | 0.00% | Reduce -81.2% | 19,300 | $270K |
| BNP Paribas Financial Markets | 0.00% | Add +119.0% | 19,082 | $267K |
| Virtu Financial LLC | 0.01% | New | 18,438 | $258K |
| Breakwater Capital Group | 0.04% | Add +13.9% | 17,096 | $239K |
| Prudential Financial Inc. | 0.00% | Reduce -56.3% | 16,878 | $236K |
| Cibc World Markets Corp. | 0.00% | Reduce -40.8% | 16,318 | $228K |
| Prelude Capital Management, LLC | 0.02% | New | 15,940 | $223K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | New | 15,329 | $214K |
| Tema ETFs LLC | 0.06% | No change | 15,174 | $212K |
| NEOS Investment Management LLC | 0.00% | No change | 15,174 | $212K |
| Empowered Funds, LLC | 0.00% | Reduce -28.2% | 14,820 | $207K |
| Jain Global LLC | 0.00% | New | 14,486 | $203K |
| STRS Ohio | 0.00% | Reduce -39.9% | 14,300 | $200K |
| Caxton Associates LLP | 0.01% | New | 14,229 | $199K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +325.6% | 13,669 | $191K |
| E Fund Management Co., Ltd. | 0.01% | Add +12.8% | 13,612 | $190K |
| Ameritas Investment Partners, Inc. | 0.01% | Add +7.4% | 13,522 | $189K |
| CANADA LIFE ASSURANCE Co | 0.00% | No change | 13,434 | $188K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 12,238 | $171K |
| Aigen Investment Management, LP | 0.02% | New | 10,662 | $149K |
| Moneco Advisors, LLC | 0.01% | Reduce -1.1% | 10,478 | $147K |
| Xponance LLC | 0.00% | New | 10,352 | $145K |
| HSBC Holdings PLC | 0.00% | Reduce -82.7% | 10,048 | $141K |
| PNC Financial Services Group, Inc. | 0.00% | Add +120.1% | 8,236 | $115K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -9.9% | 6,300 | $88K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +15.5% | 5,612 | $79K |
| KBC Group NV | 0.00% | Reduce -30.3% | 4,495 | $63K |
| Amalgamated Bank | 0.00% | No change | 4,305 | $60K |
| Shell Asset Management Co. | 0.00% | Reduce -10.0% | 4,009 | $56K |
| GF Fund Management Co. LTD. | 0.00% | No change | 3,685 | $52K |
| Assetmark, Inc. | 0.00% | Add +13.7% | 3,620 | $51K |
| Sterling Capital Management LLC | 0.00% | Add +242.4% | 3,386 | $47K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -3.1% | 2,558 | $36K |
| Simplex Trading, LLC | 0.00% | New | 2,502 | $35K |
| Cwm, LLC | 0.00% | Add +12.4% | 2,275 | $32K |
| State of Wyoming | 0.00% | New | 2,099 | $29K |
| Headlands Technologies LLC | 0.00% | New | 1,847 | $26K |
| Osaic Holdings, Inc. | 0.00% | Add +52.2% | 1,595 | $22K |
| Bartlett & Co. Wealth Management LLC | 0.00% | No change | 1,500 | $21K |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | New | 1,369 | $19K |
| Versant Capital Management, Inc | 0.00% | Add +79.6% | 1,286 | $18K |
| Comerica Bank | 0.00% | Add +8.4% | 1,284 | $18K |
| Nisa Investment Advisors, LLC | 0.00% | Reduce -14.1% | 1,217 | $17K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 1,139 | $16K |
| Mitsubishi UFJ Asset Management Co., Ltd. | 0.00% | No change | 1,001 | $14K |
| Optiver Holding B.V. | 0.00% | Add +2780.7% | 893 | $12K |
| GAMMA Investing LLC | 0.00% | Add +28.0% | 749 | $10K |
| Nemes Rush Group LLC | 0.00% | No change | 700 | $10K |
| Covestor Ltd | 0.00% | Reduce -0.2% | 580 | $8K |
| Parallel Advisors, LLC | 0.00% | Add +236.4% | 545 | $8K |
| Lanark Financial, Inc. | 0.00% | No change | 532 | $7K |
| Daiwa Securities Group Inc. | 0.00% | No change | 475 | $7K |
| Smartleaf Asset Management LLC | 0.00% | Reduce -4.0% | 454 | $6K |
| US Bancorp \de | 0.00% | Reduce -17.4% | 441 | $6K |
| NewEdge Advisors, LLC | 0.00% | No change | 400 | $6K |
| Signaturefd, LLC | 0.00% | Reduce -37.3% | 329 | $5K |
| Rothschild Investment LLC | 0.00% | Add +400.0% | 325 | $5K |
| Private Wealth Management Group, LLC | 0.00% | New | 296 | $4K |
| Allworth Financial LP | 0.00% | Reduce -9.2% | 275 | $4K |
| Huntington National Bank | 0.00% | Reduce -61.0% | 270 | $4K |
| City State Bank | 0.00% | No change | 250 | $3K |
| Elevation Point Wealth Partners, LLC | 0.00% | New | 201 | $3K |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -90.5% | 200 | $3K |
| National Bank of Canada | 0.00% | Add +145.7% | 172 | $2K |
| Parkside Financial Bank & Trust | 0.00% | New | 150 | $2K |
| Physician Wealth Advisors, Inc. | 0.00% | New | 140 | $2K |
| Bell Investment Advisors, Inc | 0.00% | Add +136.5% | 123 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | Reduce -16.9% | 123 | $2K |
| EverSource Wealth Advisors, LLC | 0.00% | Reduce -73.3% | 115 | $2K |
| Farther Finance Advisors, LLC | 0.00% | Add +1428.6% | 107 | $1K |
| Your Advocates Ltd., LLP | 0.00% | No change | 100 | $1K |
| Harbour Investments, Inc. | 0.00% | No change | 100 | $1K |
| Rise Advisors, LLC | 0.00% | New | 74 | $1K |
| True Wealth Design, LLC | 0.00% | New | 56 | $784 |
| Arax Advisory Partners | 0.00% | New | 52 | $728 |
| Fortitude Family Office, LLC | 0.00% | New | 41 | $574 |
| Blue Trust, Inc. | 0.00% | New | 40 | $560 |
| Bare Financial Services, Inc | 0.00% | New | 36 | $504 |
| CIBC Private Wealth Group LLC | 0.00% | New | 35 | $490 |
| Brooklyn Investment Group | 0.00% | New | 31 | $434 |
| WealthTrak Capital Management LLC | 0.00% | New | 10 | $140 |
| Private Wealth Asset Management, LLC | 0.00% | Reduce -79.0% | 8 | $112 |
| SBI Securities Co., Ltd. | 0.00% | No change | 5 | $70 |
| SJS Investment Consulting Inc. | 0.00% | Add +33.3% | 4 | $56 |
| Global Retirement Partners, LLC | 0.00% | — | 3 | $42 |
| HFM Investment Advisors, LLC | 0.00% | New | 3 | $42 |
| Rialto Wealth Management, LLC | 0.00% | New | 2 | $28 |
| Truvestments Capital LLC | 0.00% | New | 1 | $18 |
| Bay Harbor Wealth Management, LLC | 0.00% | No change | 1 | $13 |
| Avion Wealth | 0.00% | Add +60.0% | 40 | $0 |
| Hemington Wealth Management | 0.00% | Add +112.5% | 34 | $0 |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.