Denali TherapeuticsDNLI
13F holders, Q1 2026 (March 31)269holders +19
46new positions
28sold out
4famous investors
$19.14avg. 13F price*
At the end of Q1 2026, 269 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 19 from Q4 2025. 46 opened new positions and 28 sold out. The largest holders were BlackRock, Inc. ($250.3M), Baillie Gifford & Co. ($231.7M) and T. Rowe Price Investment Management, Inc. ($163.6M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 46 | $67.9M |
| Exits | 28 | $87.1M |
All 13F filers, Q4 2025 → Q1 2026: 16,385,852 shares bought and 14,832,082 shares sold, net +1,553,770 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 269 holders
| BlackRock, Inc. | 0.00% | Add +2.5% | 13,034,434 | $250.3M |
| Baillie Gifford & Co. | 0.24% | Reduce -2.0% | 12,066,479 | $231.7M |
| T. Rowe Price Investment Management, Inc. | 0.11% | Add +17.4% | 8,519,192 | $163.6M |
| Temasek Holdings (Private) Ltd | 0.45% | No change | 7,012,974 | $134.6M |
| State Street Corp. | 0.00% | Add +0.1% | 6,272,001 | $120.4M |
| Vanguard Capital Management LLC | 0.00% | — | 6,147,957 | $118.0M |
| Vanguard Portfolio Management LLC | 0.01% | — | 6,120,160 | $117.5M |
| FMR LLC | 0.00% | Reduce -25.0% | 4,575,374 | $87.8M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -11.1% | 4,432,314 | $85.1M |
| Goldman Sachs Group Inc. | 0.01% | Add +14.9% | 4,407,255 | $84.6M |
| Baker Bros. Advisors LP | 0.41% | No change | 3,731,695 | $71.6M |
| Geode Capital Management, LLC | 0.00% | Add +7.8% | 3,727,114 | $71.6M |
| Holocene Advisors, LP | 0.15% | Add +1.4% | 3,195,429 | $61.4M |
| Dimensional Fund Advisors LP | 0.01% | Add +13.4% | 2,692,175 | $51.7M |
| UBS Group AG | 0.01% | Add +6.9% | 2,571,344 | $49.4M |
| Pictet Asset Management Holding SA | 0.05% | Add +92.5% | 2,558,865 | $48.4M |
| Capital Research Global Investors | 0.01% | Reduce -32.6% | 2,514,588 | $48.3M |
| Alliancebernstein L.P. | 0.02% | Reduce -18.7% | 2,893,618 | $47.8M |
| T. Rowe Price Associates Inc. | 0.01% | Reduce -37.1% | 2,464,146 | $47.3M |
| Fisher Asset Management | 0.02% | Reduce -5.9% | 2,436,895 | $46.8M |
| Crestline Management, L.P. | 91.74% | Reduce -21.4% | 2,210,732 | $42.4M |
| Alyeska Investment Group, L.P. | 0.11% | Add +126.0% | 1,941,123 | $37.3M |
| Lynx1 Capital Management LP | 5.71% | Add +8.1% | 1,880,303 | $36.1M |
| ADAR1 Capital Management, LLC | 2.18% | Add +3490.9% | 1,871,455 | $35.9M |
| Aberdeen Group plc | 0.06% | Reduce -8.8% | 1,854,446 | $35.6M |
| Casdin Capital, LLC | 2.68% | No change | 1,840,000 | $35.3M |
| Vestal Point Capital, LP | 0.95% | Add +281.4% | 1,773,326 | $34.0M |
| Principal Financial Group Inc. | 0.02% | Reduce -3.0% | 1,478,486 | $28.4M |
| Siren, L.L.C. | 0.74% | No change | 1,396,513 | $26.8M |
| Defilade Capital Management, L.P. | 3.67% | Add +107.1% | 1,359,969 | $26.1M |
| Northern Trust Corp. | 0.00% | Add +9.2% | 1,310,656 | $25.2M |
| Millennium Management | 0.02% | Add +240.2% | 1,257,950 | $24.2M |
| Foresite Capital Management VI LLC | 5.05% | Add +21.0% | 1,209,971 | $23.2M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +0.6% | 1,207,399 | $23.2M |
| Bank of America Corp. | 0.00% | Add +21.7% | 1,134,183 | $21.8M |
| Morgan Stanley | 0.00% | Reduce -9.4% | 1,104,757 | $21.2M |
| Candriam S.C.A. | 0.11% | Reduce -5.7% | 1,099,845 | $21.1M |
| Artisan Partners Limited Partnership | 0.03% | New | 1,099,719 | $21.1M |
| Marshall Wace, LLP | 0.02% | Add +29.8% | 991,268 | $19.0M |
| Vanguard Fiduciary Trust Co. | 0.00% | — | 949,695 | $18.2M |
| American Century Companies Inc. | 0.01% | Add +146.8% | 935,692 | $18.0M |
| Bank of New York Mellon Corp | 0.00% | Add +0.8% | 768,039 | $14.7M |
| Clearstead Advisors, LLC | 0.13% | New | 737,990 | $14.2M |
| Cercano Management LLC | 0.52% | No change | 625,000 | $12.0M |
| Masters Capital Management LLC | 1.70% | Reduce -40.0% | 600,000 | $11.5M |
| Ensign Peak Advisors, Inc | 0.02% | No change | 515,721 | $9.9M |
| Segall Bryant & Hamill, LLC | 0.14% | Reduce -4.9% | 510,543 | $9.8M |
| Stempoint Capital LP | 1.57% | Add +1.8% | 426,561 | $8.2M |
| Woodline Partners LP | 0.03% | Add +219.1% | 364,082 | $7.0M |
| Hudson Bay Capital Management LP | 0.04% | Reduce -23.0% | 346,360 | $6.7M |
| DAFNA Capital Management LLC | 1.41% | No change | 318,500 | $6.1M |
| Invesco Ltd. | 0.00% | Add +6.3% | 310,196 | $6.0M |
| JPMorgan Chase & Co. | 0.00% | Add +88.4% | 323,989 | $5.9M |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.01% | Reduce -0.8% | 296,503 | $5.7M |
| Braidwell LP | 0.22% | New | 296,324 | $5.7M |
| Nuveen, LLC | 0.00% | Add +7.3% | 295,586 | $5.7M |
| Marex Group Ltd | 0.06% | Reduce 0.0% | 287,000 | $5.5M |
| Swiss National Bank | 0.00% | No change | 273,800 | $5.3M |
| Schroder Investment Management Group | 0.00% | Reduce -36.6% | 285,820 | $5.2M |
| TD Asset Management Inc | 0.00% | Reduce -24.6% | 255,766 | $4.9M |
| Privium Fund Management B.V. | 1.02% | New | 254,857 | $4.9M |
| Palo Alto Investors LP | 0.69% | Reduce -63.4% | 234,582 | $4.5M |
| Great Lakes Advisors, LLC | 0.04% | New | 227,110 | $4.4M |
| Edmond DE Rothschild Holding S.A. | 0.06% | No change | 225,680 | $4.3M |
| Groupama Asset Managment | 0.06% | Add +36.6% | 207,130 | $4.0M |
| Burkehill Global Management, LP | 0.20% | No change | 200,000 | $3.8M |
| Rhenman & Partners Asset Management AB | 0.47% | Add +99.0% | 199,000 | $3.8M |
| SCS Capital Management LLC | 0.04% | No change | 197,998 | $3.8M |
| Balyasny Asset Management L.P. | 0.01% | New | 195,108 | $3.7M |
| Rhumbline Advisers | 0.00% | Add +0.7% | 184,248 | $3.5M |
| Citadel Advisors | 0.00% | Reduce -76.7% | 181,417 | $3.5M |
| Teachers Retirement System of the State of Kentucky | 0.02% | Add +8.1% | 166,181 | $3.2M |
| Sector Gamma As | 0.74% | New | 162,710 | $3.1M |
| California State Teachers Retirement System | 0.00% | Add +25.6% | 162,576 | $3.1M |
| Susquehanna Portfolio Strategies, LLC | 0.05% | Reduce -5.8% | 157,896 | $3.0M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -21.3% | 150,687 | $2.9M |
| Man Group plc | 0.01% | Add +183.8% | 139,045 | $2.7M |
| Alps Advisors Inc. | 0.01% | Add +7.0% | 129,105 | $2.5M |
| New York State Common Retirement Fund | 0.00% | Add +233.0% | 128,119 | $2.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Reduce -31.9% | 125,442 | $2.4M |
| VANGUARD ASSET MANAGEMENT, Ltd | 0.00% | — | 125,243 | $2.4M |
| Deutsche Bank AG | 0.00% | Add +14.5% | 120,368 | $2.3M |
| Nomura Asset Management International Inc. | 0.00% | Add +6.5% | 114,524 | $2.2M |
| B. Metzler seel. Sohn & Co. AG | 0.02% | No change | 112,300 | $2.2M |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | Add +135.3% | 111,694 | $2.1M |
| Legal & General Group Plc | 0.00% | Reduce -16.0% | 110,250 | $2.1M |
| D.A. Davidson & Co. | 0.01% | Add +3.1% | 110,235 | $2.1M |
| Wells Fargo & Company | 0.00% | Reduce -44.4% | 107,657 | $2.1M |
| AQR Capital Management | 0.00% | Add +166.9% | 102,579 | $2.0M |
| Ghisallo Capital Management LLC | 0.05% | No change | 100,000 | $1.9M |
| Integrated Wealth Concepts LLC | 0.02% | Add +5.3% | 99,554 | $1.9M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Add +40.5% | 99,503 | $1.9M |
| Lumbard & Kellner, LLC | 0.63% | New | 94,782 | $1.8M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Reduce -26.1% | 95,193 | $1.8M |
| Ameriprise Financial Inc. | 0.00% | Reduce -50.3% | 89,534 | $1.7M |
| State of Wisconsin Investment Board | 0.00% | Add +11.9% | 82,357 | $1.6M |
| XTX Topco Ltd | 0.03% | New | 78,567 | $1.5M |
| Y-Intercept (Hong Kong) Ltd | 0.03% | Reduce -16.6% | 78,007 | $1.5M |
| MetLife Investment Management, LLC | 0.01% | Add +3.2% | 77,558 | $1.5M |
| Creative Planning | 0.00% | Add +21.9% | 74,069 | $1.4M |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.