Denali TherapeuticsDNLI
13F holders, Q4 2024 (December 31)223holders +6
29new positions
28sold out
4famous investors
$20.38avg. 13F price*
At the end of Q4 2024, 223 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 6 from Q3 2024. 29 opened new positions and 28 sold out. The largest holders were BlackRock, Inc. ($283.7M), Baillie Gifford & Co. ($251.0M) and Vanguard Group Inc. ($245.0M). 4 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Ken Griffin (0.0% of Citadel Advisors's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Denali Therapeutics Inc.
- CUSIP
- 24823R105
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 29 | $26.8M |
| Exits | 28 | $17.1M |
All 13F filers, Q3 2024 → Q4 2024: 8,603,785 shares bought and 7,689,606 shares sold, net +914,179 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 223 holders
| BlackRock, Inc. | 0.01% | Add +1.0% | 13,920,245 | $283.7M |
| Baillie Gifford & Co. | 0.19% | Reduce -7.7% | 12,313,931 | $251.0M |
| Vanguard Group Inc. | 0.00% | Add +7.5% | 12,021,230 | $245.0M |
| Wellington Management Group LLP | 0.04% | Reduce -8.2% | 9,847,951 | $200.7M |
| FMR LLC | 0.01% | Add +2.4% | 8,019,746 | $163.4M |
| Capital Research Global Investors | 0.02% | Reduce -30.8% | 5,477,211 | $111.6M |
| Temasek Holdings (Private) Ltd | 0.43% | No change | 5,355,832 | $109.2M |
| State Street Corp. | 0.00% | Add +6.9% | 4,544,973 | $92.6M |
| Crestline Management, L.P. | 3.06% | Reduce -3.4% | 4,310,732 | $87.9M |
| Baker Bros. Advisors LP | 0.82% | No change | 3,731,695 | $76.1M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.02% | Reduce -4.4% | 3,582,874 | $73.0M |
| Alliancebernstein L.P. | 0.02% | Add +8.8% | 3,315,642 | $67.6M |
| T. Rowe Price Associates Inc. | 0.01% | Add +6.6% | 3,058,615 | $62.3M |
| Geode Capital Management, LLC | 0.00% | Reduce -0.7% | 2,935,283 | $59.8M |
| Camber Capital Management LP | 1.81% | Add +12.5% | 2,250,000 | $45.9M |
| Dimensional Fund Advisors LP | 0.01% | Add +19.0% | 1,855,036 | $37.8M |
| Marshall Wace, LLP | 0.05% | Reduce -9.1% | 1,788,737 | $36.5M |
| Bank of New York Mellon Corp | 0.00% | Reduce -6.6% | 1,242,987 | $25.3M |
| Morgan Stanley | 0.00% | Reduce -29.6% | 1,229,140 | $25.0M |
| Northern Trust Corp. | 0.00% | Add +10.7% | 1,201,518 | $24.5M |
| Principal Financial Group Inc. | 0.01% | Reduce -8.7% | 1,130,963 | $23.0M |
| Norges Bank | 0.00% | Add +168.1% | 1,065,608 | $21.7M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -22.7% | 1,057,523 | $21.6M |
| Artisan Partners Limited Partnership | 0.03% | Reduce -3.4% | 1,054,523 | $21.5M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +1.3% | 1,028,462 | $21.0M |
| Casdin Capital, LLC | 1.35% | No change | 990,000 | $20.2M |
| UBS Group AG | 0.00% | Add +503.1% | 852,861 | $17.4M |
| Siren, L.L.C. | 0.75% | No change | 834,028 | $17.0M |
| Candriam S.C.A. | 0.10% | Reduce -11.6% | 832,977 | $17.0M |
| Citadel Advisors | 0.02% | Add +6.8% | 829,911 | $16.9M |
| Fisher Asset Management | 0.01% | Add +44.8% | 792,499 | $16.2M |
| Yiheng Capital Management, L.P. | 3.16% | Add +16.7% | 700,098 | $14.3M |
| Cercano Management LLC | 0.32% | No change | 625,000 | $12.7M |
| Stempoint Capital LP | 2.99% | Add +107.2% | 584,328 | $11.9M |
| Polar Asset Management Partners Inc. | 0.22% | Add +1240.9% | 551,092 | $11.2M |
| Point72 Asset Management | 0.03% | Add +64.5% | 548,739 | $11.2M |
| American Century Companies Inc. | 0.01% | Add +6.5% | 480,529 | $9.8M |
| Balyasny Asset Management L.P. | 0.02% | Add +822.4% | 416,074 | $8.5M |
| Clarius Group, LLC | 0.57% | No change | 409,995 | $8.4M |
| Millennium Management | 0.01% | Add +571.8% | 404,224 | $8.2M |
| Aberdeen Group plc | 0.02% | Add +10.6% | 402,282 | $8.2M |
| Nuveen Asset Management, LLC | 0.00% | Reduce -50.4% | 355,057 | $7.2M |
| Ensign Peak Advisors, Inc | 0.01% | No change | 346,304 | $7.1M |
| Pier Capital, LLC | 0.97% | Add +97.7% | 332,319 | $6.8M |
| Qube Research & Technologies Ltd | 0.01% | New | 311,507 | $6.3M |
| AXA S.A. | 0.02% | Reduce -14.8% | 293,755 | $6.0M |
| Segall Bryant & Hamill, LLC | 0.08% | New | 289,075 | $5.9M |
| Barclays PLC | 0.00% | Add +8.7% | 278,067 | $5.7M |
| Deutsche Bank AG | 0.00% | Add +15.8% | 277,853 | $5.7M |
| Bank of America Corp. | 0.00% | Reduce -22.4% | 270,333 | $5.5M |
| TD Asset Management Inc | 0.00% | Add +8.7% | 265,752 | $5.4M |
| Twinbeech Capital LP | 0.09% | New | 254,586 | $5.2M |
| Swiss National Bank | 0.00% | Add +1.1% | 253,500 | $5.2M |
| Schroder Investment Management Group | 0.00% | Add +94.7% | 247,800 | $5.0M |
| Jane Street Group, LLC | 0.01% | Reduce -38.0% | 229,165 | $4.7M |
| JPMorgan Chase & Co. | 0.00% | Reduce -5.3% | 222,983 | $4.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.8% | 208,521 | $4.2M |
| Teachers Retirement System of the State of Kentucky | 0.04% | No change | 207,124 | $4.2M |
| Edmond DE Rothschild Holding S.A. | 0.07% | No change | 205,680 | $4.2M |
| Holocene Advisors, LP | 0.01% | Add +104.3% | 199,072 | $4.1M |
| Susquehanna Fundamental Investments, LLC | 0.07% | — | 192,563 | $3.9M |
| Rhumbline Advisers | 0.00% | Add +0.3% | 190,390 | $3.9M |
| Two Sigma Investments, LP | 0.01% | Add +80.8% | 179,884 | $3.7M |
| Citigroup Inc. | 0.00% | Add +76.0% | 166,706 | $3.4M |
| Legal & General Group Plc | 0.00% | Add +5.7% | 149,513 | $3.0M |
| New York State Common Retirement Fund | 0.00% | Reduce -3.5% | 144,724 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Add +20.1% | 141,310 | $2.9M |
| Cinctive Capital Management LP | 0.14% | Reduce -12.5% | 130,445 | $2.7M |
| Invesco Ltd. | 0.00% | Reduce -41.1% | 121,478 | $2.5M |
| California State Teachers Retirement System | 0.00% | Reduce -0.8% | 120,174 | $2.4M |
| Alps Advisors Inc. | 0.01% | Add +9.5% | 116,377 | $2.4M |
| Prudential Financial Inc. | 0.00% | Reduce -5.8% | 110,593 | $2.3M |
| Groupama Asset Managment | 0.05% | Add +41.2% | 110,207 | $2.2M |
| Woodline Partners LP | 0.01% | New | 100,000 | $2.0M |
| State of Wisconsin Investment Board | 0.00% | Add +14.3% | 93,094 | $1.9M |
| Thrivent Financial for Lutherans | 0.00% | Reduce -33.0% | 92,972 | $1.9M |
| Hudson Bay Capital Management LP | 0.01% | Add +168.1% | 92,500 | $1.9M |
| Fred Alger Management, LLC | 0.01% | Reduce -24.3% | 91,807 | $1.9M |
| Wells Fargo & Company | 0.00% | Reduce -5.1% | 88,933 | $1.8M |
| State of New Jersey Common Pension Fund D | 0.01% | Add +11.3% | 86,243 | $1.8M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +4.2% | 85,075 | $1.7M |
| MetLife Investment Management, LLC | 0.01% | Add +5.9% | 76,050 | $1.5M |
| Franklin Resources Inc. | 0.00% | Reduce -6.5% | 74,862 | $1.5M |
| Susquehanna International Group, LLP | 0.00% | Add +42.0% | 71,240 | $1.5M |
| Nisa Investment Advisors, LLC | 0.01% | Add +0.2% | 66,621 | $1.4M |
| First Trust Advisors LP | 0.00% | Add +260.9% | 65,442 | $1.3M |
| Corebridge Financial, Inc. | 0.01% | Reduce -7.0% | 61,800 | $1.3M |
| Trexquant Investment LP | 0.01% | Add +147.2% | 60,656 | $1.2M |
| Janus Henderson Group PLC | 0.00% | Add +15.2% | 60,028 | $1.2M |
| Diadema Partners LP | 1.38% | — | 60,000 | $1.2M |
| DekaBank Deutsche Girozentrale | 0.00% | No change | 59,800 | $1.2M |
| Voya Investment Management LLC | 0.00% | Reduce -5.2% | 54,813 | $1.1M |
| Engineers Gate Manager LP | 0.02% | New | 53,358 | $1.1M |
| Squarepoint Ops LLC | 0.00% | Add +44.2% | 48,619 | $991K |
| Guggenheim Capital LLC | 0.01% | Add +133.5% | 48,131 | $981K |
| Creative Planning | 0.00% | Reduce -20.4% | 47,950 | $977K |
| Intech Investment Management LLC | 0.01% | Add +60.5% | 47,401 | $966K |
| MAI Capital Management | 0.01% | New | 46,526 | $948K |
| Pier 88 Investment Partners LLC | 1.13% | Reduce -23.3% | 45,410 | $925K |
| ADAR1 Capital Management, LLC | 0.19% | Reduce -56.0% | 44,826 | $914K |
"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.