Denali TherapeuticsDNLI

13F holders, Q1 2026 (March 31)
269holders +19
46new positions
28sold out
4famous investors
$19.14avg. 13F price*

At the end of Q1 2026, 269 institutions reported holding Denali Therapeutics Inc. (DNLI) in their 13F filings, up 19 from Q4 2025. 46 opened new positions and 28 sold out. The largest holders were BlackRock, Inc. ($250.3M), Baillie Gifford & Co. ($231.7M) and T. Rowe Price Investment Management, Inc. ($163.6M). 4 famous investors held it, including Israel Englander (0.0% of Millennium Management's portfolio), Ken Fisher (0.0% of Fisher Asset Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).

Company
Denali Therapeutics Inc.
CUSIP
24823R105
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300 Q1 2024: 211Q1 2024Q2 2024: 203Q2 2024Q3 2024: 217Q3 2024Q4 2024: 223Q4 2024Q1 2025: 222Q1 2025Q2 2025: 230Q2 2025Q3 2025: 240Q3 2025Q4 2025: 250Q4 2025Q1 2026: 269Q1 2026Q2 2026: 294Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions46$67.9M
Exits28$87.1M

All 13F filers, Q4 2025 → Q1 2026: 16,385,852 shares bought and 14,832,082 shares sold, net +1,553,770 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 269 holders

BlackRock, Inc. 0.00% Add +2.5% 13,034,434 $250.3M
Baillie Gifford & Co. 0.24% Reduce -2.0% 12,066,479 $231.7M
T. Rowe Price Investment Management, Inc. 0.11% Add +17.4% 8,519,192 $163.6M
Temasek Holdings (Private) Ltd 0.45% No change 7,012,974 $134.6M
State Street Corp. 0.00% Add +0.1% 6,272,001 $120.4M
Vanguard Capital Management LLC 0.00% — 6,147,957 $118.0M
Vanguard Portfolio Management LLC 0.01% — 6,120,160 $117.5M
FMR LLC 0.00% Reduce -25.0% 4,575,374 $87.8M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.02% Reduce -11.1% 4,432,314 $85.1M
Goldman Sachs Group Inc. 0.01% Add +14.9% 4,407,255 $84.6M
Baker Bros. Advisors LP 0.41% No change 3,731,695 $71.6M
Geode Capital Management, LLC 0.00% Add +7.8% 3,727,114 $71.6M
Holocene Advisors, LP 0.15% Add +1.4% 3,195,429 $61.4M
Dimensional Fund Advisors LP 0.01% Add +13.4% 2,692,175 $51.7M
UBS Group AG 0.01% Add +6.9% 2,571,344 $49.4M
Pictet Asset Management Holding SA 0.05% Add +92.5% 2,558,865 $48.4M
Capital Research Global Investors 0.01% Reduce -32.6% 2,514,588 $48.3M
Alliancebernstein L.P. 0.02% Reduce -18.7% 2,893,618 $47.8M
T. Rowe Price Associates Inc. 0.01% Reduce -37.1% 2,464,146 $47.3M
Fisher Asset Management 0.02% Reduce -5.9% 2,436,895 $46.8M
Crestline Management, L.P. 91.74% Reduce -21.4% 2,210,732 $42.4M
Alyeska Investment Group, L.P. 0.11% Add +126.0% 1,941,123 $37.3M
Lynx1 Capital Management LP 5.71% Add +8.1% 1,880,303 $36.1M
ADAR1 Capital Management, LLC 2.18% Add +3490.9% 1,871,455 $35.9M
Aberdeen Group plc 0.06% Reduce -8.8% 1,854,446 $35.6M
Casdin Capital, LLC 2.68% No change 1,840,000 $35.3M
Vestal Point Capital, LP 0.95% Add +281.4% 1,773,326 $34.0M
Principal Financial Group Inc. 0.02% Reduce -3.0% 1,478,486 $28.4M
Siren, L.L.C. 0.74% No change 1,396,513 $26.8M
Defilade Capital Management, L.P. 3.67% Add +107.1% 1,359,969 $26.1M
Northern Trust Corp. 0.00% Add +9.2% 1,310,656 $25.2M
Millennium Management 0.02% Add +240.2% 1,257,950 $24.2M
Foresite Capital Management VI LLC 5.05% Add +21.0% 1,209,971 $23.2M
Charles Schwab Investment Management Inc. 0.00% Add +0.6% 1,207,399 $23.2M
Bank of America Corp. 0.00% Add +21.7% 1,134,183 $21.8M
Morgan Stanley 0.00% Reduce -9.4% 1,104,757 $21.2M
Candriam S.C.A. 0.11% Reduce -5.7% 1,099,845 $21.1M
Artisan Partners Limited Partnership 0.03% New 1,099,719 $21.1M
Marshall Wace, LLP 0.02% Add +29.8% 991,268 $19.0M
Vanguard Fiduciary Trust Co. 0.00% — 949,695 $18.2M
American Century Companies Inc. 0.01% Add +146.8% 935,692 $18.0M
Bank of New York Mellon Corp 0.00% Add +0.8% 768,039 $14.7M
Clearstead Advisors, LLC 0.13% New 737,990 $14.2M
Cercano Management LLC 0.52% No change 625,000 $12.0M
Masters Capital Management LLC 1.70% Reduce -40.0% 600,000 $11.5M
Ensign Peak Advisors, Inc 0.02% No change 515,721 $9.9M
Segall Bryant & Hamill, LLC 0.14% Reduce -4.9% 510,543 $9.8M
Stempoint Capital LP 1.57% Add +1.8% 426,561 $8.2M
Woodline Partners LP 0.03% Add +219.1% 364,082 $7.0M
Hudson Bay Capital Management LP 0.04% Reduce -23.0% 346,360 $6.7M
DAFNA Capital Management LLC 1.41% No change 318,500 $6.1M
Invesco Ltd. 0.00% Add +6.3% 310,196 $6.0M
JPMorgan Chase & Co. 0.00% Add +88.4% 323,989 $5.9M
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.01% Reduce -0.8% 296,503 $5.7M
Braidwell LP 0.22% New 296,324 $5.7M
Nuveen, LLC 0.00% Add +7.3% 295,586 $5.7M
Marex Group Ltd 0.06% Reduce 0.0% 287,000 $5.5M
Swiss National Bank 0.00% No change 273,800 $5.3M
Schroder Investment Management Group 0.00% Reduce -36.6% 285,820 $5.2M
TD Asset Management Inc 0.00% Reduce -24.6% 255,766 $4.9M
Privium Fund Management B.V. 1.02% New 254,857 $4.9M
Palo Alto Investors LP 0.69% Reduce -63.4% 234,582 $4.5M
Great Lakes Advisors, LLC 0.04% New 227,110 $4.4M
Edmond DE Rothschild Holding S.A. 0.06% No change 225,680 $4.3M
Groupama Asset Managment 0.06% Add +36.6% 207,130 $4.0M
Burkehill Global Management, LP 0.20% No change 200,000 $3.8M
Rhenman & Partners Asset Management AB 0.47% Add +99.0% 199,000 $3.8M
SCS Capital Management LLC 0.04% No change 197,998 $3.8M
Balyasny Asset Management L.P. 0.01% New 195,108 $3.7M
Rhumbline Advisers 0.00% Add +0.7% 184,248 $3.5M
Citadel Advisors 0.00% Reduce -76.7% 181,417 $3.5M
Teachers Retirement System of the State of Kentucky 0.02% Add +8.1% 166,181 $3.2M
Sector Gamma As 0.74% New 162,710 $3.1M
California State Teachers Retirement System 0.00% Add +25.6% 162,576 $3.1M
Susquehanna Portfolio Strategies, LLC 0.05% Reduce -5.8% 157,896 $3.0M
Rafferty Asset Management, LLC 0.01% Reduce -21.3% 150,687 $2.9M
Man Group plc 0.01% Add +183.8% 139,045 $2.7M
Alps Advisors Inc. 0.01% Add +7.0% 129,105 $2.5M
New York State Common Retirement Fund 0.00% Add +233.0% 128,119 $2.5M
Manufacturers Life Insurance Company, The 0.00% Reduce -31.9% 125,442 $2.4M
VANGUARD ASSET MANAGEMENT, Ltd 0.00% — 125,243 $2.4M
Deutsche Bank AG 0.00% Add +14.5% 120,368 $2.3M
Nomura Asset Management International Inc. 0.00% Add +6.5% 114,524 $2.2M
B. Metzler seel. Sohn & Co. AG 0.02% No change 112,300 $2.2M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +135.3% 111,694 $2.1M
Legal & General Group Plc 0.00% Reduce -16.0% 110,250 $2.1M
D.A. Davidson & Co. 0.01% Add +3.1% 110,235 $2.1M
Wells Fargo & Company 0.00% Reduce -44.4% 107,657 $2.1M
AQR Capital Management 0.00% Add +166.9% 102,579 $2.0M
Ghisallo Capital Management LLC 0.05% No change 100,000 $1.9M
Integrated Wealth Concepts LLC 0.02% Add +5.3% 99,554 $1.9M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.00% Add +40.5% 99,503 $1.9M
Lumbard & Kellner, LLC 0.63% New 94,782 $1.8M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.00% Reduce -26.1% 95,193 $1.8M
Ameriprise Financial Inc. 0.00% Reduce -50.3% 89,534 $1.7M
State of Wisconsin Investment Board 0.00% Add +11.9% 82,357 $1.6M
XTX Topco Ltd 0.03% New 78,567 $1.5M
Y-Intercept (Hong Kong) Ltd 0.03% Reduce -16.6% 78,007 $1.5M
MetLife Investment Management, LLC 0.01% Add +3.2% 77,558 $1.5M
Creative Planning 0.00% Add +21.9% 74,069 $1.4M
WINTON GROUP Ltd 0.05% Add +460.5% 71,179 $1.4M
Profund Advisors LLC 0.05% Reduce -4.8% 68,227 $1.3M
1492 Capital Management LLC 0.49% Reduce -0.1% 67,417 $1.3M
Polen Capital Management LLC 0.01% Add +142.8% 65,301 $1.3M
Pier 88 Investment Partners LLC 1.84% Reduce -5.0% 64,800 $1.2M
DekaBank Deutsche Girozentrale 0.00% No change 59,800 $1.2M
Janus Henderson Group PLC 0.00% No change 60,028 $1.2M
Vanguard Global Advisers, LLC 0.00% — 58,779 $1.1M
Knights of Columbus Asset Advisors LLC 0.06% Add +14.9% 56,329 $1.1M
Pathstone Holdings, LLC 0.00% Add +9.5% 56,325 $1.1M
Wellington Management Group LLP 0.00% Reduce -2.2% 53,363 $1.0M
Sei Investments Co. 0.00% New 52,235 $1.0M
Barclays PLC 0.00% Reduce -87.2% 52,084 $1.0M
Ironwood Investment Management LLC 0.42% Add +2.2% 52,062 $1000K
Dana Investment Advisors, Inc. 0.03% Add +2.6% 51,922 $997K
Envestnet Asset Management Inc. 0.00% Add +31.6% 50,900 $977K
Susquehanna International Group, LLP 0.00% Add +45.2% 50,475 $969K
Franklin Resources Inc. 0.00% Reduce -19.1% 48,732 $936K
State of New Jersey Common Pension Fund D 0.00% Add +0.1% 47,471 $911K
Employees Retirement System of Texas 0.01% No change 47,177 $906K
SG Americas Securities, LLC 0.00% Reduce -68.8% 46,642 $896K
MAI Capital Management 0.01% Add +0.1% 46,590 $895K
Handelsbanken Fonder AB 0.00% No change 43,800 $841K
Virtu Financial LLC 0.03% New 43,362 $833K
China Universal Asset Management Co., Ltd. 0.06% Add +70.1% 40,643 $780K
BNP Paribas Financial Markets 0.00% Add +157.4% 39,893 $766K
Citigroup Inc. 0.00% Add +26.9% 39,278 $754K
Intech Investment Management LLC 0.01% Reduce -26.0% 38,931 $747K
Police & Firemen's Retirement System of New Jersey 0.01% Add +5.3% 38,545 $740K
Arizona State Retirement System 0.00% Reduce -1.3% 38,153 $733K
Vanguard Investments Australia, Ltd. 0.00% — 37,410 $718K
Nomura Asset Management Co. Ltd. 0.00% Add +0.0% 36,732 $705K
Seven Fleet Capital Management LP 0.21% New 35,286 $677K
Jefferies Financial Group Inc. 0.01% New 34,425 $661K
Raymond James Financial Inc. 0.00% Add +34.4% 34,383 $660K
State Board of Administration of Florida Retirement System 0.00% No change 34,168 $656K
Thrivent Financial for Lutherans 0.00% No change 32,555 $626K
Jane Street Group, LLC 0.00% Reduce -25.1% 32,147 $617K
KLP Kapitalforvaltning As 0.00% Add +3.3% 30,900 $593K
Prudential Financial Inc. 0.00% New 30,570 $587K
Quantinno Capital Management LP 0.00% Add +14.7% 30,170 $579K
SBI Okasan Asset Management Co.Ltd. 0.02% Add +63.9% 29,500 $533K
ProShare Advisors LLC 0.00% Reduce -9.6% 27,737 $533K
Rockefeller Capital Management L.P. 0.00% Add +1950.2% 25,935 $498K
Erste Asset Management GmbH 0.00% No change 26,900 $486K
Voya Investment Management LLC 0.00% Reduce -0.6% 23,672 $455K
Twinbeech Capital LP 0.05% New 23,000 $442K
Tower Research Capital LLC (TRC) 0.01% Add +62.1% 20,978 $403K
E Fund Management Co., Ltd. 0.01% — 18,942 $364K
Amundi 0.00% New 18,604 $357K
Martingale Asset Management L P 0.01% No change 18,535 $356K
Mariner, LLC 0.00% New 18,131 $348K
Teacher Retirement System of Texas 0.00% Reduce -12.9% 17,882 $343K
Bellevue Group AG 0.01% Add +148.9% 17,766 $341K
Osaic Holdings, Inc. 0.00% Add +1428.2% 16,413 $315K
Victory Capital Management Inc. 0.00% Add +7.5% 16,194 $311K
Engineers Gate Manager LP 0.00% New 16,110 $309K
Caitong International Asset Management Co., Ltd 0.06% New 15,861 $305K
Empowered Funds, LLC 0.00% Add +39.4% 15,787 $303K
Breakwater Capital Group 0.04% Reduce -4.8% 15,586 $299K
Virtus Investment Advisers, LLC 0.08% Add +2.5% 15,166 $291K
Contravisory Investment Management, Inc. 0.06% New 14,451 $277K
Intrust Bank NA 0.02% Add +28.4% 14,339 $275K
Russell Investments Group, Ltd. 0.00% Add +4.4% 14,058 $270K
Guggenheim Capital LLC 0.00% Add +10.9% 13,825 $265K
CANADA LIFE ASSURANCE Co 0.00% No change 13,434 $259K
Xponance LLC 0.00% Add +26.1% 13,240 $254K
Perbak Capital Partners LLP 0.06% Add +4.5% 13,175 $253K
Capstone Investment Advisors, LLC 0.00% Reduce -66.6% 12,963 $249K
Cerity Partners LLC 0.00% New 12,658 $243K
Simplex Trading, LLC 0.01% New 12,315 $236K
LPL Financial LLC 0.00% Add +16.9% 12,274 $236K
Public Employees Retirement Association of Colorado 0.00% No change 12,238 $235K
Atria Investments, Inc 0.00% New 12,112 $233K
HighTower Advisors, LLC 0.00% Add +1.8% 11,971 $230K
Ameritas Investment Partners, Inc. 0.01% Add +5.3% 11,654 $224K
Vanguard Personalized Indexing Management, LLC 0.00% Reduce -1.0% 11,622 $223K
B. Riley Wealth Advisors, Inc. 0.01% New 12,213 $221K
Pinnacle Wealth Planning Services, Inc. 0.02% Add +285.7% 11,406 $219K
Cetera Investment Advisers 0.00% New 11,059 $212K
DNB Asset Management AS 0.00% New 10,959 $210K
Gilbert & Cook, Inc. 0.03% New 10,871 $209K
Headlands Technologies LLC 0.02% Reduce -77.2% 10,557 $203K
PNC Financial Services Group, Inc. 0.00% Add +8.7% 9,220 $177K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +16.1% 8,272 $159K
Lanark Financial, Inc. 0.01% Add +16.5% 7,617 $146K
Royal Bank of Canada 0.00% Reduce -33.5% 7,535 $145K
Assetmark, Inc. 0.00% Add +0.2% 5,199 $100K
KBC Group NV 0.00% Reduce -21.1% 4,943 $95K
Eurizon Capital SGR S.p.A. 0.00% No change 5,045 $92K
Cwm, LLC 0.00% Add +78.5% 4,651 $89K
Sterling Capital Management LLC 0.00% Reduce -37.9% 4,493 $86K
GF Fund Management Co. LTD. 0.00% Add +14.3% 3,294 $63K
Fifth Third Bancorp 0.00% New 2,847 $55K
Nisa Investment Advisors, LLC 0.00% Add +67.3% 2,424 $47K
Versant Capital Management, Inc 0.00% No change 1,476 $28K
Bartlett & Co. Wealth Management LLC 0.00% No change 1,500 $28K
GAMMA Investing LLC 0.00% Add +48.4% 1,428 $27K
Kemnay Advisory Services Inc. 0.00% New 1,134 $22K
Smartleaf Asset Management LLC 0.00% Reduce -15.7% 1,107 $20K
Mitsubishi UFJ Asset Management Co., Ltd. 0.00% No change 1,001 $19K
Los Angeles Capital Management LLC 0.00% Add +47.9% 927 $18K
US Bancorp \de 0.00% Add +8.2% 902 $17K
Optiver Holding B.V. 0.00% Add +111.7% 866 $17K
Advisory Services Network, LLC 0.00% New 848 $16K
Quadrant Capital Group LLC 0.00% No change 758 $15K
Nemes Rush Group LLC 0.00% No change 700 $13K
UMB Bank, n.a. 0.00% Add +138.2% 624 $12K
Quantbot Technologies LP 0.00% New 512 $10K
Mowery & Schoenfeld Wealth Management, LLC 0.01% New 500 $10K
Owl Creek Wealth Partners LLC 0.00% — 450 $9K
Huntington National Bank 0.00% Reduce -14.5% 420 $8K
NewEdge Advisors, LLC 0.00% No change 400 $8K
SBI Securities Co., Ltd. 0.00% Reduce -69.9% 368 $7K
Parallel Advisors, LLC 0.00% No change 358 $7K
Covestor Ltd 0.00% Reduce -44.4% 322 $6K
Arax Advisory Partners 0.00% Add +52.0% 301 $6K
Private Wealth Management Group, LLC 0.00% No change 296 $6K
Rothschild Investment LLC 0.00% Add +47.7% 288 $6K
Eastern Bank 0.00% No change 282 $5K
Allworth Financial LP 0.00% Add +211.1% 280 $5K
Farther Finance Advisors, LLC 0.00% Add +26.2% 255 $5K
EverSource Wealth Advisors, LLC 0.00% Add +23.7% 256 $5K
City State Bank 0.00% No change 250 $5K
Signaturefd, LLC 0.00% Add +4.8% 241 $5K
Comprehensive Financial Planning, Inc. 0.00% No change 200 $4K
Parkside Financial Bank & Trust 0.00% No change 189 $4K
Root Financial Partners, LLC 0.00% Add +88.0% 188 $4K
Aster Capital Management (DIFC) Ltd 0.00% Reduce -92.9% 246 $3K
MassMutual Private Wealth & Trust, FSB 0.00% No change 143 $3K
Steward Partners Investment Advisory, LLC 0.00% New 136 $3K
Ascentis Independent Advisors 0.00% New 130 $2K
Your Advocates Ltd., LLP 0.00% No change 100 $2K
Johnson Financial Group, Inc. 0.00% No change 81 $2K
Physician Wealth Advisors, Inc. 0.00% No change 76 $1K
TD Private Client Wealth LLC 0.00% No change 71 $1K
Bayforest Capital Ltd 0.00% Reduce -99.7% 67 $1K
Rossby Financial, LCC 0.00% New 65 $1K
WPG Advisers, LLC 0.00% New 66 $1K
CVA Family Office, LLC 0.00% New 63 $1K
Larson Financial Group LLC 0.00% Add +63.2% 62 $1K
True Wealth Design, LLC 0.00% Add +1.8% 57 $1K
Hantz Financial Services, Inc. 0.00% No change 57 $1K
Essential Partners LLC 0.00% New 45 $864
Wealth Preservation Advisors, LLC 0.00% New 43 $826
Transamerica Financial Advisors, LLC 0.00% New 40 $768
Blue Trust, Inc. 0.00% No change 40 $768
Bell Investment Advisors, Inc 0.00% No change 38 $730
Jones Financial Companies LLLP 0.00% New 39 $708
Manchester Capital Management LLC 0.00% No change 36 $692
Fortitude Family Office, LLC 0.00% Add +400.0% 35 $672
Cornerstone Financial Management LLC 0.00% No change 34 $653
Keating Financial Advisory Services, Inc. 0.00% Add +65.0% 33 $634
Sunbelt Securities, Inc. 0.00% No change 22 $422
Basecamp Wealth Advisors LLC 0.00% Reduce -45.2% 17 $326
SJS Investment Consulting Inc. 0.00% Add +300.0% 16 $308
Atlantic Private Wealth, LLC 0.00% No change 10 $192
Cullen/Frost Bankers, Inc. 0.00% New 10 $192
IFP Advisors, Inc 0.00% No change 9 $173
JFS Wealth Advisors, LLC 0.00% No change 8 $154
Bay Harbor Wealth Management, LLC 0.00% Add +100.0% 6 $115
Rialto Wealth Management, LLC 0.00% Reduce -37.5% 5 $96
HFM Investment Advisors, LLC 0.00% Reduce -44.4% 5 $96
Dunhill Financial, LLC 0.00% No change 2 $40
DiNuzzo Private Wealth, Inc. 0.00% New 2 $39
Raffa Wealth Management, LLC 0.00% New 1 $19
Vermillion Wealth Management, Inc. 0.00% New 1 $19
Curio Wealth, LLC 0.00% New 1 $19
Avion Wealth 0.00% No change 40 $0

"% of holder's portfolio" is DNLI's weight in each manager's 13F, not the share of Denali Therapeutics Inc. the manager owns.