Structure TherapeuticsGPCR
13F holders, Q2 2025 (June 30)172holders +22
37new positions
16sold out
5famous investors
$20.74avg. 13F price*
At the end of Q2 2025, 172 institutions reported holding Structure Therapeutics Inc. (GPCR) in their 13F filings, up 22 from Q1 2025. 37 opened new positions and 16 sold out. The largest holders were Wellington Management Group LLP ($142.6M), Deep Track Capital, LP ($106.5M) and FMR LLC ($101.9M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Structure Therapeutics Inc.
- CUSIP
- 86366E106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $31.0M |
| Exits | 16 | $74.8M |
All 13F filers, Q1 2025 → Q2 2025: 9,051,012 shares bought and 10,331,496 shares sold, net −1,280,484 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 172 holders
| Wellington Management Group LLP | 0.03% | Reduce -11.8% | 6,875,769 | $142.6M |
| Deep Track Capital, LP | 3.42% | Add +25.2% | 5,133,917 | $106.5M |
| FMR LLC | 0.01% | Reduce -16.5% | 4,914,965 | $101.9M |
| Janus Henderson Group PLC | 0.05% | Add +5.0% | 4,573,006 | $94.9M |
| Baker Bros. Advisors LP | 0.50% | Add +593.9% | 2,508,767 | $52.0M |
| BVF Inc. | 1.31% | No change | 1,771,417 | $36.7M |
| Capital International Investors | 0.01% | Reduce -0.0% | 1,618,876 | $33.6M |
| Ameriprise Financial Inc. | 0.01% | Add +7.2% | 1,588,198 | $32.9M |
| Ra Capital Management, L.P. | 0.53% | No change | 1,517,418 | $31.5M |
| Citadel Advisors | 0.02% | Add +33.9% | 1,328,479 | $27.6M |
| Casdin Capital, LLC | 2.31% | Add +75.0% | 1,225,000 | $25.4M |
| Millennium Management | 0.02% | Add +54.4% | 1,220,055 | $25.3M |
| Vestal Point Capital, LP | 1.31% | Reduce -32.9% | 1,200,000 | $24.9M |
| Orbimed Advisors LLC | 0.63% | Add +83.9% | 1,199,300 | $24.9M |
| Rock Springs Capital Management LP | 1.47% | Add +0.3% | 1,135,879 | $23.6M |
| TCG Crossover Management, LLC | 2.52% | No change | 1,063,000 | $22.0M |
| Morgan Stanley | 0.00% | Add +32.5% | 917,346 | $19.0M |
| Principal Financial Group Inc. | 0.01% | Add +12.8% | 853,202 | $17.7M |
| Logos Global Management LP | 2.35% | Add +100.0% | 850,000 | $17.6M |
| Franklin Resources Inc. | 0.00% | Add +0.2% | 741,783 | $15.4M |
| Driehaus Capital Management LLC | 0.11% | Reduce -47.1% | 672,792 | $14.0M |
| Catalio Capital Management, LP | 2.92% | Reduce -4.9% | 670,575 | $13.9M |
| American Century Companies Inc. | 0.01% | Reduce -3.7% | 491,193 | $10.2M |
| Federated Hermes, Inc. | 0.02% | Reduce -60.0% | 468,300 | $9.7M |
| Pacific Heights Asset Management LLC | 0.51% | New | 460,000 | $9.5M |
| Monashee Investment Management LLC | 4.91% | Add +46.8% | 430,000 | $8.9M |
| Invesco Ltd. | 0.00% | Add +7.7% | 424,548 | $8.8M |
| Aberdeen Group plc | 0.01% | Add +61.4% | 401,624 | $8.3M |
| Handelsbanken Fonder AB | 0.03% | No change | 380,000 | $7.9M |
| Deerfield Management Company, L.P. | 0.16% | No change | 373,407 | $7.7M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -54.6% | 352,868 | $7.3M |
| Bellevue Group AG | 0.16% | Add +57.2% | 348,527 | $7.2M |
| Point72 Asset Management | 0.02% | Add +43.8% | 330,000 | $6.8M |
| Schonfeld Strategic Advisors LLC | 0.05% | New | 321,591 | $6.7M |
| ArrowMark Colorado Holdings LLC | 0.11% | Add +21.9% | 298,937 | $6.2M |
| HSG Holding Ltd | 0.28% | No change | 266,062 | $5.5M |
| BlackRock, Inc. | 0.00% | Reduce -57.0% | 243,334 | $5.0M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -32.1% | 220,174 | $4.6M |
| Foresite Capital Management VI LLC | 2.45% | Reduce -50.0% | 210,000 | $4.4M |
| Pier Capital, LLC | 0.63% | Reduce -6.6% | 198,478 | $4.1M |
| Ikarian Capital, LLC | 1.26% | Reduce -30.7% | 183,085 | $3.8M |
| Readystate Asset Management LP | 0.28% | Reduce -62.9% | 178,612 | $3.7M |
| Woodline Partners LP | 0.02% | Add +0.6% | 176,453 | $3.7M |
| Marshall Wace, LLP | 0.00% | Add +474.9% | 176,060 | $3.7M |
| Silverarc Capital Management, LLC | 0.75% | Reduce -6.6% | 175,636 | $3.6M |
| Nantahala Capital Management, LLC | 0.25% | No change | 168,553 | $3.5M |
| Canada Pension Plan Investment Board | 0.00% | New | 167,800 | $3.5M |
| UBS Group AG | 0.00% | Reduce -35.8% | 152,981 | $3.2M |
| CCG Wealth Management, LLC | 1.64% | No change | 150,000 | $3.1M |
| Susquehanna Fundamental Investments, LLC | 0.08% | Reduce -11.6% | 139,717 | $2.9M |
| Rhenman & Partners Asset Management AB | 0.35% | Add +93.0% | 135,100 | $2.8M |
| First Light Asset Management, LLC | 0.33% | Reduce -7.7% | 122,226 | $2.5M |
| Point72 Europe (London) LLP | 0.12% | Add +28.7% | 116,697 | $2.4M |
| Renaissance Technologies | 0.00% | Add +608.2% | 111,900 | $2.3M |
| Eversept Partners, LP | 0.21% | New | 99,338 | $2.1M |
| Sphera Funds Management LTD. | 0.52% | Add +14.2% | 95,931 | $2.0M |
| HighVista Strategies LLC | 0.66% | Add +393.3% | 86,621 | $1.8M |
| Trexquant Investment LP | 0.02% | Reduce -32.2% | 81,588 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Add +11.2% | 75,802 | $1.6M |
| Platinum Investment Management Ltd. | 0.10% | No change | 74,900 | $1.6M |
| Verition Fund Management LLC | 0.01% | Add +272.7% | 72,984 | $1.5M |
| Cubist Systematic Strategies, LLC | 0.02% | Add +30.8% | 71,690 | $1.5M |
| Banque Pictet & Cie SA | 0.02% | Reduce -13.9% | 70,401 | $1.5M |
| Jain Global LLC | 0.02% | Add +193.4% | 69,369 | $1.4M |
| BNP Paribas Financial Markets | 0.00% | Add +1357.2% | 65,836 | $1.4M |
| Osaic Holdings, Inc. | 0.00% | Add +101.8% | 63,362 | $1.3M |
| Jump Financial, LLC | 0.02% | Add +105.9% | 63,234 | $1.3M |
| Exchange Traded Concepts, LLC | 0.02% | Add +58.6% | 61,732 | $1.3M |
| Bank of Montreal | 0.00% | Add +9.1% | 58,073 | $1.2M |
| DAFNA Capital Management LLC | 0.34% | No change | 59,000 | $1.2M |
| Macquarie Group Ltd. | 0.00% | No change | 58,000 | $1.2M |
| Boothbay Fund Management, LLC | 0.04% | Reduce -25.4% | 57,622 | $1.2M |
| PFM Health Sciences, LP | 0.10% | Add +40.1% | 56,594 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Add +18.5% | 54,181 | $1.1M |
| Exome Asset Management LLC | 0.92% | Reduce -47.8% | 53,744 | $1.1M |
| Sectoral Asset Management Inc. | 0.70% | Add +52.5% | 51,369 | $1.1M |
| TD Asset Management Inc | 0.00% | No change | 43,686 | $906K |
| JPMorgan Chase & Co. | 0.00% | Reduce -68.4% | 42,442 | $880K |
| Quinn Opportunity Partners LLC | 0.07% | Add +90.9% | 42,000 | $871K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.1% | 40,789 | $846K |
| Susquehanna Portfolio Strategies, LLC | 0.02% | New | 39,960 | $829K |
| Mariner, LLC | 0.00% | Add +118.8% | 39,501 | $819K |
| Walleye Capital LLC | 0.01% | New | 38,673 | $802K |
| TrueMark Investments, LLC | 0.17% | Reduce -3.7% | 37,765 | $783K |
| Two Sigma Advisers, LP | 0.00% | New | 36,100 | $749K |
| Birchview Capital, LP | 0.74% | New | 36,000 | $747K |
| Sofinnova Investments, Inc. | 0.05% | Reduce -1.7% | 34,353 | $712K |
| State Street Corp. | 0.00% | Add +211.5% | 33,459 | $694K |
| Alps Advisors Inc. | 0.00% | Reduce -27.9% | 31,073 | $644K |
| Voya Investment Management LLC | 0.00% | Add +18.2% | 30,655 | $636K |
| Caption Management, LLC | 0.05% | Add +204.4% | 28,174 | $584K |
| Nomura Asset Management Co. Ltd. | 0.00% | Reduce -14.2% | 24,874 | $516K |
| DCF Advisers, LLC | 0.25% | New | 24,750 | $513K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 24,600 | $510K |
| Simplex Trading, LLC | 0.01% | Add +12.1% | 23,094 | $478K |
| Tema ETFs LLC | 0.13% | Add +1.3% | 22,880 | $475K |
| NEOS Investment Management LLC | 0.01% | Add +1.3% | 22,880 | $475K |
| Alliancebernstein L.P. | 0.00% | New | 22,499 | $467K |
| Tejara Capital Ltd | 0.22% | New | 22,400 | $465K |
| Headlands Technologies LLC | 0.06% | Add +555.5% | 22,338 | $463K |
"% of holder's portfolio" is GPCR's weight in each manager's 13F, not the share of Structure Therapeutics Inc. the manager owns.