Structure TherapeuticsGPCR
13F holders, Q2 2025 (June 30)172holders +22
37new positions
16sold out
5famous investors
$20.74avg. 13F price*
At the end of Q2 2025, 172 institutions reported holding Structure Therapeutics Inc. (GPCR) in their 13F filings, up 22 from Q1 2025. 37 opened new positions and 16 sold out. The largest holders were Wellington Management Group LLP ($142.6M), Deep Track Capital, LP ($106.5M) and FMR LLC ($101.9M). 5 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Steve Cohen (0.0% of Point72 Asset Management's portfolio).
- Company
- Structure Therapeutics Inc.
- CUSIP
- 86366E106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $31.0M |
| Exits | 16 | $74.8M |
All 13F filers, Q1 2025 → Q2 2025: 9,051,012 shares bought and 10,331,496 shares sold, net −1,280,484 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 172 holders
| Wellington Management Group LLP | 0.03% | Reduce -11.8% | 6,875,769 | $142.6M |
| Deep Track Capital, LP | 3.42% | Add +25.2% | 5,133,917 | $106.5M |
| FMR LLC | 0.01% | Reduce -16.5% | 4,914,965 | $101.9M |
| Janus Henderson Group PLC | 0.05% | Add +5.0% | 4,573,006 | $94.9M |
| Baker Bros. Advisors LP | 0.50% | Add +593.9% | 2,508,767 | $52.0M |
| BVF Inc. | 1.31% | No change | 1,771,417 | $36.7M |
| Capital International Investors | 0.01% | Reduce -0.0% | 1,618,876 | $33.6M |
| Ameriprise Financial Inc. | 0.01% | Add +7.2% | 1,588,198 | $32.9M |
| Ra Capital Management, L.P. | 0.53% | No change | 1,517,418 | $31.5M |
| Citadel Advisors | 0.02% | Add +33.9% | 1,328,479 | $27.6M |
| Casdin Capital, LLC | 2.31% | Add +75.0% | 1,225,000 | $25.4M |
| Millennium Management | 0.02% | Add +54.4% | 1,220,055 | $25.3M |
| Vestal Point Capital, LP | 1.31% | Reduce -32.9% | 1,200,000 | $24.9M |
| Orbimed Advisors LLC | 0.63% | Add +83.9% | 1,199,300 | $24.9M |
| Rock Springs Capital Management LP | 1.47% | Add +0.3% | 1,135,879 | $23.6M |
| TCG Crossover Management, LLC | 2.52% | No change | 1,063,000 | $22.0M |
| Morgan Stanley | 0.00% | Add +32.5% | 917,346 | $19.0M |
| Principal Financial Group Inc. | 0.01% | Add +12.8% | 853,202 | $17.7M |
| Logos Global Management LP | 2.35% | Add +100.0% | 850,000 | $17.6M |
| Franklin Resources Inc. | 0.00% | Add +0.2% | 741,783 | $15.4M |
| Driehaus Capital Management LLC | 0.11% | Reduce -47.1% | 672,792 | $14.0M |
| Catalio Capital Management, LP | 2.92% | Reduce -4.9% | 670,575 | $13.9M |
| American Century Companies Inc. | 0.01% | Reduce -3.7% | 491,193 | $10.2M |
| Federated Hermes, Inc. | 0.02% | Reduce -60.0% | 468,300 | $9.7M |
| Pacific Heights Asset Management LLC | 0.51% | New | 460,000 | $9.5M |
| Monashee Investment Management LLC | 4.91% | Add +46.8% | 430,000 | $8.9M |
| Invesco Ltd. | 0.00% | Add +7.7% | 424,548 | $8.8M |
| Aberdeen Group plc | 0.01% | Add +61.4% | 401,624 | $8.3M |
| Handelsbanken Fonder AB | 0.03% | No change | 380,000 | $7.9M |
| Deerfield Management Company, L.P. | 0.16% | No change | 373,407 | $7.7M |
| T. Rowe Price Associates Inc. | 0.00% | Reduce -54.6% | 352,868 | $7.3M |
| Bellevue Group AG | 0.16% | Add +57.2% | 348,527 | $7.2M |
| Point72 Asset Management | 0.02% | Add +43.8% | 330,000 | $6.8M |
| Schonfeld Strategic Advisors LLC | 0.05% | New | 321,591 | $6.7M |
| ArrowMark Colorado Holdings LLC | 0.11% | Add +21.9% | 298,937 | $6.2M |
| HSG Holding Ltd | 0.28% | No change | 266,062 | $5.5M |
| BlackRock, Inc. | 0.00% | Reduce -57.0% | 243,334 | $5.0M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -32.1% | 220,174 | $4.6M |
| Foresite Capital Management VI LLC | 2.45% | Reduce -50.0% | 210,000 | $4.4M |
| Pier Capital, LLC | 0.63% | Reduce -6.6% | 198,478 | $4.1M |
| Ikarian Capital, LLC | 1.26% | Reduce -30.7% | 183,085 | $3.8M |
| Readystate Asset Management LP | 0.28% | Reduce -62.9% | 178,612 | $3.7M |
| Woodline Partners LP | 0.02% | Add +0.6% | 176,453 | $3.7M |
| Marshall Wace, LLP | 0.00% | Add +474.9% | 176,060 | $3.7M |
| Silverarc Capital Management, LLC | 0.75% | Reduce -6.6% | 175,636 | $3.6M |
| Nantahala Capital Management, LLC | 0.25% | No change | 168,553 | $3.5M |
| Canada Pension Plan Investment Board | 0.00% | New | 167,800 | $3.5M |
| UBS Group AG | 0.00% | Reduce -35.8% | 152,981 | $3.2M |
| CCG Wealth Management, LLC | 1.64% | No change | 150,000 | $3.1M |
| Susquehanna Fundamental Investments, LLC | 0.08% | Reduce -11.6% | 139,717 | $2.9M |
| Rhenman & Partners Asset Management AB | 0.35% | Add +93.0% | 135,100 | $2.8M |
| First Light Asset Management, LLC | 0.33% | Reduce -7.7% | 122,226 | $2.5M |
| Point72 Europe (London) LLP | 0.12% | Add +28.7% | 116,697 | $2.4M |
| Renaissance Technologies | 0.00% | Add +608.2% | 111,900 | $2.3M |
| Eversept Partners, LP | 0.21% | New | 99,338 | $2.1M |
| Sphera Funds Management LTD. | 0.52% | Add +14.2% | 95,931 | $2.0M |
| HighVista Strategies LLC | 0.66% | Add +393.3% | 86,621 | $1.8M |
| Trexquant Investment LP | 0.02% | Reduce -32.2% | 81,588 | $1.7M |
| Susquehanna International Group, LLP | 0.00% | Add +11.2% | 75,802 | $1.6M |
| Platinum Investment Management Ltd. | 0.10% | No change | 74,900 | $1.6M |
| Verition Fund Management LLC | 0.01% | Add +272.7% | 72,984 | $1.5M |
| Cubist Systematic Strategies, LLC | 0.02% | Add +30.8% | 71,690 | $1.5M |
| Banque Pictet & Cie SA | 0.02% | Reduce -13.9% | 70,401 | $1.5M |
| Jain Global LLC | 0.02% | Add +193.4% | 69,369 | $1.4M |
| BNP Paribas Financial Markets | 0.00% | Add +1357.2% | 65,836 | $1.4M |
| Osaic Holdings, Inc. | 0.00% | Add +101.8% | 63,362 | $1.3M |
| Jump Financial, LLC | 0.02% | Add +105.9% | 63,234 | $1.3M |
| Exchange Traded Concepts, LLC | 0.02% | Add +58.6% | 61,732 | $1.3M |
| Bank of Montreal | 0.00% | Add +9.1% | 58,073 | $1.2M |
| DAFNA Capital Management LLC | 0.34% | No change | 59,000 | $1.2M |
| Macquarie Group Ltd. | 0.00% | No change | 58,000 | $1.2M |
| Boothbay Fund Management, LLC | 0.04% | Reduce -25.4% | 57,622 | $1.2M |
| PFM Health Sciences, LP | 0.10% | Add +40.1% | 56,594 | $1.2M |
| Geode Capital Management, LLC | 0.00% | Add +18.5% | 54,181 | $1.1M |
| Exome Asset Management LLC | 0.92% | Reduce -47.8% | 53,744 | $1.1M |
| Sectoral Asset Management Inc. | 0.70% | Add +52.5% | 51,369 | $1.1M |
| TD Asset Management Inc | 0.00% | No change | 43,686 | $906K |
| JPMorgan Chase & Co. | 0.00% | Reduce -68.4% | 42,442 | $880K |
| Quinn Opportunity Partners LLC | 0.07% | Add +90.9% | 42,000 | $871K |
| Manufacturers Life Insurance Company, The | 0.00% | Add +0.1% | 40,789 | $846K |
| Susquehanna Portfolio Strategies, LLC | 0.02% | New | 39,960 | $829K |
| Mariner, LLC | 0.00% | Add +118.8% | 39,501 | $819K |
| Walleye Capital LLC | 0.01% | New | 38,673 | $802K |
| TrueMark Investments, LLC | 0.17% | Reduce -3.7% | 37,765 | $783K |
| Two Sigma Advisers, LP | 0.00% | New | 36,100 | $749K |
| Birchview Capital, LP | 0.74% | New | 36,000 | $747K |
| Sofinnova Investments, Inc. | 0.05% | Reduce -1.7% | 34,353 | $712K |
| State Street Corp. | 0.00% | Add +211.5% | 33,459 | $694K |
| Alps Advisors Inc. | 0.00% | Reduce -27.9% | 31,073 | $644K |
| Voya Investment Management LLC | 0.00% | Add +18.2% | 30,655 | $636K |
| Caption Management, LLC | 0.05% | Add +204.4% | 28,174 | $584K |
| Nomura Asset Management Co. Ltd. | 0.00% | Reduce -14.2% | 24,874 | $516K |
| DCF Advisers, LLC | 0.25% | New | 24,750 | $513K |
| OMERS ADMINISTRATION Corp | 0.00% | New | 24,600 | $510K |
| Simplex Trading, LLC | 0.01% | Add +12.1% | 23,094 | $478K |
| Tema ETFs LLC | 0.13% | Add +1.3% | 22,880 | $475K |
| NEOS Investment Management LLC | 0.01% | Add +1.3% | 22,880 | $475K |
| Alliancebernstein L.P. | 0.00% | New | 22,499 | $467K |
| Tejara Capital Ltd | 0.22% | New | 22,400 | $465K |
| Headlands Technologies LLC | 0.06% | Add +555.5% | 22,338 | $463K |
| Paloma Partners Management Co | 0.19% | New | 20,950 | $435K |
| SG Americas Securities, LLC | 0.00% | New | 19,239 | $399K |
| Teachers Retirement System of the State of Kentucky | 0.00% | No change | 17,651 | $366K |
| Prelude Capital Management, LLC | 0.03% | Reduce -33.4% | 17,070 | $354K |
| Quadrature Capital Ltd | 0.01% | New | 16,079 | $334K |
| Engineers Gate Manager LP | 0.00% | New | 15,862 | $329K |
| Squarepoint Ops LLC | 0.00% | New | 15,176 | $315K |
| ADAR1 Capital Management, LLC | 0.05% | Reduce -57.9% | 15,000 | $311K |
| Good Life Advisors, LLC | 0.02% | Add +15.4% | 15,000 | $311K |
| Virtu Financial LLC | 0.02% | New | 14,779 | $307K |
| Capital Fund Management S.A. | 0.00% | Reduce -82.0% | 14,350 | $298K |
| Bank of America Corp. | 0.00% | Reduce -74.9% | 13,908 | $288K |
| MASO CAPITAL PARTNERS Ltd | 0.49% | New | 13,000 | $270K |
| D. E. Shaw & Co. | 0.00% | Add +4.3% | 12,165 | $252K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +0.1% | 11,967 | $248K |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.00% | Reduce -84.5% | 11,914 | $247K |
| LPL Financial LLC | 0.00% | New | 11,599 | $241K |
| Griffin Asset Management, Inc. | 0.03% | New | 11,205 | $232K |
| Brandywine Managers, LLC | 0.23% | No change | 11,057 | $229K |
| Atom Investors LP | 0.02% | New | 11,027 | $229K |
| Allianz Asset Management GmbH | 0.00% | New | 11,000 | $228K |
| Envestnet Asset Management Inc. | 0.00% | New | 10,676 | $221K |
| DNB Asset Management AS | 0.00% | New | 10,635 | $221K |
| Bleichroeder LP | 0.05% | No change | 10,000 | $207K |
| PEAK6 LLC | 0.01% | No change | 9,445 | $196K |
| Parallel Advisors, LLC | 0.00% | New | 8,264 | $171K |
| Group One Trading LLC | 0.01% | Reduce -83.5% | 8,065 | $167K |
| Royal Bank of Canada | 0.00% | Add +104.3% | 7,582 | $157K |
| Wells Fargo & Company | 0.00% | Reduce -1.7% | 7,223 | $150K |
| Signaturefd, LLC | 0.00% | Add +6550.0% | 6,650 | $138K |
| Barclays PLC | 0.00% | Add +19.1% | 6,328 | $131K |
| Raymond James Financial Inc. | 0.00% | New | 6,229 | $129K |
| PNC Financial Services Group, Inc. | 0.00% | Add +29.1% | 4,415 | $92K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -18.3% | 4,232 | $88K |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Reduce -29.5% | 4,170 | $86K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +11.8% | 4,120 | $85K |
| ANTIPODES PARTNERS Ltd | 0.00% | Reduce -31.0% | 2,932 | $61K |
| Quantbot Technologies LP | 0.00% | Reduce -80.0% | 2,888 | $60K |
| Assetmark, Inc. | 0.00% | Add +39.9% | 2,877 | $60K |
| Steward Partners Investment Advisory, LLC | 0.00% | Add +4.9% | 2,640 | $55K |
| FNY Investment Advisers, LLC | 0.02% | Add +41.7% | 1,700 | $35K |
| Citigroup Inc. | 0.00% | Reduce -98.5% | 1,600 | $33K |
| GF Fund Management Co. LTD. | 0.00% | No change | 1,525 | $32K |
| State of Wyoming | 0.00% | New | 1,330 | $28K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +50.9% | 898 | $19K |
| Caitong International Asset Management Co., Ltd | 0.01% | Add +122.1% | 835 | $17K |
| Jones Financial Companies LLLP | 0.00% | Reduce -75.6% | 767 | $16K |
| Farther Finance Advisors, LLC | 0.00% | New | 670 | $14K |
| Dynamic Wealth Strategies, LLC | 0.01% | New | 550 | $11K |
| SouthState Bank Corp | 0.00% | New | 500 | $10K |
| Country Trust Bank | 0.00% | New | 500 | $10K |
| GAMMA Investing LLC | 0.00% | Reduce -5.1% | 481 | $10K |
| Rhumbline Advisers | 0.00% | No change | 450 | $9K |
| Cwm, LLC | 0.00% | Add +255.0% | 355 | $7K |
| North Star Investment Management Corp. | 0.00% | No change | 330 | $7K |
| Wolff Wiese Magana LLC | 0.00% | Add +113.4% | 286 | $6K |
| Daiwa Securities Group Inc. | 0.00% | No change | 226 | $5K |
| National Bank of Canada | 0.00% | Reduce -93.2% | 200 | $4K |
| Private Wealth Management Group, LLC | 0.00% | No change | 196 | $4K |
| EverSource Wealth Advisors, LLC | 0.00% | New | 170 | $4K |
| Ameritas Advisory Services, LLC | 0.00% | New | 100 | $2K |
| Northwestern Mutual Wealth Management Co. | 0.00% | New | 58 | $1K |
| Washington Trust Advisors, Inc. | 0.00% | No change | 41 | $850 |
| CIBC Private Wealth Group LLC | 0.00% | New | 33 | $684 |
| Brooklyn Investment Group | 0.00% | New | 32 | $664 |
| Federation des caisses Desjardins du Quebec | 0.00% | No change | 20 | $415 |
| US Bancorp \de | 0.00% | No change | 13 | $270 |
| MAI Capital Management | 0.00% | No change | 10 | $208 |
| Global Retirement Partners, LLC | 0.00% | — | 10 | $207 |
| Cullen/Frost Bankers, Inc. | 0.00% | No change | 8 | $166 |
| Huntington National Bank | 0.00% | No change | 2 | $41 |
| Point72 Asia (Singapore) Pte. Ltd. | 0.00% | No change | 1 | $21 |
"% of holder's portfolio" is GPCR's weight in each manager's 13F, not the share of Structure Therapeutics Inc. the manager owns.