Structure TherapeuticsGPCR
13F holders, Q1 2026 (March 31)196holders −1
37new positions
39sold out
4famous investors
$48.29avg. 13F price*
At the end of Q1 2026, 196 institutions reported holding Structure Therapeutics Inc. (GPCR) in their 13F filings, down 1 from Q4 2025. 37 opened new positions and 39 sold out. The largest holders were FMR LLC ($405.0M), Wellington Management Group LLP ($349.9M) and Avoro Capital Advisors LLC ($316.0M). 4 famous investors held it, including Paul Tudor Jones (0.0% of Tudor Investment Corporation's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Structure Therapeutics Inc.
- CUSIP
- 86366E106
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q4 2025 → Q1 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 37 | $84.1M |
| Exits | 39 | $195.8M |
All 13F filers, Q4 2025 → Q1 2026: 6,879,512 shares bought and 6,549,624 shares sold, net +329,888 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 196 holders
| FMR LLC | 0.02% | Reduce -3.5% | 8,403,449 | $405.0M |
| Wellington Management Group LLP | 0.07% | Add +1.9% | 7,260,287 | $349.9M |
| Avoro Capital Advisors LLC | 3.11% | No change | 6,555,555 | $316.0M |
| Janus Henderson Group PLC | 0.12% | Add +5.2% | 5,354,981 | $258.3M |
| Deep Track Capital, LP | 4.26% | Add +4.1% | 4,279,848 | $206.3M |
| BVF Inc. | 5.31% | Reduce -0.6% | 3,459,358 | $166.7M |
| Morgan Stanley | 0.01% | Add +10.4% | 2,305,457 | $111.1M |
| T. Rowe Price Associates Inc. | 0.01% | Add +19.7% | 2,000,696 | $96.4M |
| Principal Financial Group Inc. | 0.05% | Add +36.6% | 1,753,764 | $84.5M |
| Driehaus Capital Management LLC | 0.56% | Reduce -4.0% | 1,577,356 | $76.0M |
| Orbimed Advisors LLC | 1.61% | Add +27.0% | 1,475,403 | $71.1M |
| American Century Companies Inc. | 0.04% | Add +183.7% | 1,438,031 | $69.3M |
| Baker Bros. Advisors LP | 0.40% | No change | 1,432,529 | $69.0M |
| Siren, L.L.C. | 1.78% | Add +23.2% | 1,328,698 | $64.0M |
| Casdin Capital, LLC | 4.29% | No change | 1,175,000 | $56.6M |
| Capitolis Liquid Global Markets LLC | 0.35% | — | 1,151,300 | $55.5M |
| Alliancebernstein L.P. | 0.01% | Reduce -24.7% | 638,813 | $44.4M |
| Deerfield Management Company, L.P. | 0.52% | No change | 767,993 | $37.0M |
| Pacific Heights Asset Management LLC | 1.21% | Add +7.1% | 750,000 | $36.1M |
| Rock Springs Capital Management LP | 1.82% | Reduce -14.4% | 640,217 | $30.9M |
| Paradigm Biocapital Advisors LP | 0.54% | New | 545,287 | $26.3M |
| Franklin Resources Inc. | 0.01% | Reduce -38.9% | 531,595 | $25.6M |
| Logos Global Management LP | 1.24% | Reduce -16.7% | 500,000 | $24.1M |
| Healthcare of Ontario Pension Plan Trust Fund | 0.04% | No change | 467,800 | $22.5M |
| BlackRock, Inc. | 0.00% | Add +2.8% | 441,975 | $21.3M |
| Aberdeen Group plc | 0.03% | Add +47.9% | 391,809 | $18.9M |
| Deutsche Bank AG | 0.01% | Reduce -60.5% | 331,867 | $16.0M |
| National Bank of Canada | 0.02% | Add +15.1% | 305,400 | $14.7M |
| Balyasny Asset Management L.P. | 0.03% | Add +41.0% | 304,934 | $14.7M |
| Goldman Sachs Group Inc. | 0.00% | Add +16.1% | 260,543 | $12.6M |
| Catalio Capital Management, LP | 2.57% | Add +1.0% | 255,379 | $12.3M |
| Voloridge Investment Management, LLC | 0.05% | Add +2.0% | 254,969 | $12.3M |
| SEB Asset Management AB | 0.05% | — | 245,043 | $11.8M |
| Pentwater Capital Management LP | 0.08% | New | 245,000 | $11.8M |
| Parkman Healthcare Partners LLC | 1.16% | Add +322.0% | 232,093 | $11.2M |
| Bank of America Corp. | 0.00% | Add +617.0% | 227,132 | $10.9M |
| Ameriprise Financial Inc. | 0.00% | Reduce -23.1% | 219,516 | $10.6M |
| UBS Group AG | 0.00% | Add +5.2% | 212,919 | $10.3M |
| Sio Capital Management, LLC | 1.45% | Add +3.8% | 209,093 | $10.1M |
| D. E. Shaw & Co. | 0.01% | Add +2274.9% | 204,790 | $9.9M |
| TD Asset Management Inc | 0.01% | Add +17.2% | 204,762 | $9.9M |
| Stempoint Capital LP | 1.86% | Reduce -43.0% | 200,267 | $9.7M |
| JPMorgan Chase & Co. | 0.00% | Add +1542.5% | 212,803 | $9.4M |
| Woodline Partners LP | 0.03% | Add +54.0% | 190,808 | $9.2M |
| ArrowMark Colorado Holdings LLC | 0.24% | Reduce -30.6% | 188,195 | $9.1M |
| Two Sigma Investments, LP | 0.01% | Add +89.9% | 181,415 | $8.7M |
| Cormorant Asset Management, LP | 0.43% | New | 175,000 | $8.4M |
| Millennium Management | 0.01% | Add +10.7% | 168,931 | $8.1M |
| Schonfeld Strategic Advisors LLC | 0.07% | Add +1795.6% | 165,426 | $8.0M |
| Holocene Advisors, LP | 0.02% | New | 159,009 | $7.7M |
| TCG Crossover Management, LLC | 0.19% | Reduce -84.8% | 140,411 | $6.8M |
| Eversept Partners, LP | 0.44% | Add +8.2% | 138,036 | $6.7M |
| Nomura Asset Management International Inc. | 0.01% | Add +62.2% | 134,015 | $6.5M |
| NEXTBio Capital Management LP | 2.98% | Add +41.1% | 133,239 | $6.4M |
| HSG Holding Ltd | 0.38% | No change | 266,062 | $6.2M |
| Rhenman & Partners Asset Management AB | 0.76% | Reduce -13.2% | 128,100 | $6.2M |
| B Group, Inc. | 4.56% | Add +41.7% | 127,500 | $6.1M |
| Davern Capital Partners, LP | 1.67% | New | 126,461 | $6.1M |
| PFM Health Sciences, LP | 0.65% | Add +85.2% | 126,383 | $6.1M |
| HighVista Strategies LLC | 1.65% | Reduce -35.8% | 123,909 | $6.0M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +19.1% | 114,814 | $5.5M |
| Universal- Beteiligungs- und Servicegesellschaft mbH | 0.01% | Add +32.0% | 109,638 | $5.3M |
| Trexquant Investment LP | 0.04% | Add +19.9% | 107,884 | $5.2M |
| Jump Financial, LLC | 0.09% | New | 107,857 | $5.2M |
| Jones Hill Capital LP | 1.04% | — | 100,593 | $4.8M |
| Birchview Capital, LP | 2.74% | Add +11.1% | 100,000 | $4.8M |
| Peregrine Capital Management LLC | 0.17% | Add +15.2% | 97,117 | $4.7M |
| Soleus Capital Management, L.P. | 0.16% | Reduce -11.1% | 80,000 | $3.9M |
| Tudor Investment Corporation | 0.02% | Add +114.8% | 75,301 | $3.6M |
| Boxer Capital Management, LLC | 0.47% | No change | 75,000 | $3.6M |
| Qube Research & Technologies Ltd | 0.01% | New | 73,599 | $3.5M |
| Diadema Partners LP | 1.44% | New | 72,234 | $3.5M |
| Marshall Wace, LLP | 0.00% | Reduce -59.0% | 69,107 | $3.3M |
| Geode Capital Management, LLC | 0.00% | Add +23.1% | 67,862 | $3.3M |
| Platinum Investment Management Ltd. | 0.81% | Reduce -23.9% | 66,864 | $3.2M |
| Jefferies Financial Group Inc. | 0.04% | Reduce -39.2% | 62,592 | $3.0M |
| Susquehanna Portfolio Strategies, LLC | 0.04% | Reduce -11.1% | 60,517 | $2.9M |
| Burkehill Global Management, LP | 0.15% | No change | 60,000 | $2.9M |
| Alps Advisors Inc. | 0.01% | Add +16.0% | 57,667 | $2.8M |
| Susquehanna International Group, LLP | 0.00% | Add +520.5% | 55,842 | $2.7M |
| Renaissance Technologies | 0.00% | Reduce -51.6% | 55,800 | $2.7M |
| Sphera Funds Management LTD. | 0.42% | Add +23.9% | 50,800 | $2.4M |
| Monashee Investment Management LLC | 1.56% | Reduce -77.8% | 50,000 | $2.4M |
| Buckland Partners Management Co LLC | 1.46% | No change | 50,000 | $2.4M |
| Seven Grand Managers, LLC | 0.16% | No change | 50,000 | $2.4M |
| Banque Pictet & Cie SA | 0.03% | Reduce -17.6% | 49,367 | $2.4M |
| State Street Corp. | 0.00% | Reduce -1.3% | 47,581 | $2.3M |
| Pier Capital, LLC | 0.38% | Reduce -2.5% | 47,551 | $2.3M |
| DAFNA Capital Management LLC | 0.52% | Add +25.7% | 46,500 | $2.2M |
| Brevan Howard Capital Management LP | 0.02% | Reduce -45.2% | 47,266 | $2.2M |
| ANTIPODES PARTNERS Ltd | 0.04% | Reduce -2.0% | 45,361 | $2.2M |
| Raymond James Financial Inc. | 0.00% | Add +1.7% | 45,139 | $2.2M |
| Osaic Holdings, Inc. | 0.00% | Reduce -25.0% | 44,416 | $2.1M |
| Voya Investment Management LLC | 0.00% | Reduce -19.7% | 44,410 | $2.1M |
| Bank of Montreal | 0.00% | Reduce -26.4% | 39,984 | $1.9M |
| Headlands Technologies LLC | 0.20% | Reduce -15.0% | 37,156 | $1.8M |
| Flax Pond Capital, LLC | 1.40% | Reduce -26.1% | 36,000 | $1.7M |
| PSquared Asset Management AG | 0.59% | New | 35,000 | $1.7M |
| Mariner, LLC | 0.00% | Reduce -21.9% | 34,480 | $1.7M |
| Private Capital Advisors, Inc. | 0.19% | Add +368.0% | 34,389 | $1.7M |
"% of holder's portfolio" is GPCR's weight in each manager's 13F, not the share of Structure Therapeutics Inc. the manager owns.