Karyopharm TherapeuticsKPTI
13F holders, Q1 2025 (March 31)47holders
3famous investors
$3.74avg. 13F price*
At the end of Q1 2025, 47 institutions reported holding Karyopharm Therapeutics Inc. (KPTI) in their 13F filings. The largest holders were Vanguard Group Inc. ($1.9M), Adage Capital Partners Gp, L.L.C. ($1.6M) and Eversept Partners, LP ($962K). 3 famous investors held it, including Ken Griffin (0.0% of Citadel Advisors's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).
- Company
- Karyopharm Therapeutics Inc.
- CUSIP
- 48576U205
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 4 | $562K |
| Exits | 0 | $0 |
Ownership 47 holders
| Vanguard Group Inc. | 0.00% | No change | 510,294 | $1.9M |
| Adage Capital Partners Gp, L.L.C. | 0.00% | No change | 421,322 | $1.6M |
| Eversept Partners, LP | 0.11% | Add +84.7% | 257,154 | $962K |
| BlackRock, Inc. | 0.00% | Reduce -3.4% | 242,742 | $908K |
| Citadel Advisors | 0.00% | No change | 206,909 | $774K |
| JPMorgan Chase & Co. | 0.00% | Add +827.5% | 170,790 | $639K |
| Catalio Capital Management, LP | 0.14% | No change | 155,622 | $582K |
| T. Rowe Price Investment Management, Inc. | 0.00% | New | 139,646 | $523K |
| Avidity Partners Management LP | 0.10% | No change | 134,566 | $503K |
| Bank of America Corp. | 0.00% | Add +1132.8% | 132,908 | $497K |
| Marshall Wace, LLP | 0.00% | Reduce -19.8% | 128,451 | $480K |
| C WorldWide Group Holding A/S | 0.00% | No change | 100,000 | $374K |
| Geode Capital Management, LLC | 0.00% | Add +7.3% | 99,640 | $373K |
| UBS Group AG | 0.00% | Add +863.1% | 93,612 | $350K |
| Goldman Sachs Group Inc. | 0.00% | Reduce -4.1% | 85,410 | $319K |
| Renaissance Technologies | 0.00% | Reduce -23.6% | 61,214 | $229K |
| Millennium Management | 0.00% | Reduce -28.1% | 55,367 | $207K |
| Altium Capital Management LLC | 0.54% | No change | 49,333 | $185K |
| State Street Corp. | 0.00% | No change | 29,495 | $110K |
| BNP Paribas Financial Markets | 0.00% | Reduce -66.9% | 28,961 | $108K |
| Ikarian Capital, LLC | 0.03% | No change | 27,257 | $102K |
| Shay Capital LLC | 0.03% | Add +121.5% | 25,417 | $95K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.00% | Reduce -76.1% | 23,640 | $88K |
| Northern Trust Corp. | 0.00% | No change | 18,910 | $71K |
| Susquehanna International Group, LLP | 0.00% | Reduce -73.9% | 11,548 | $43K |
| Jane Street Group, LLC | 0.00% | Reduce -77.1% | 11,420 | $43K |
| Bank of New York Mellon Corp | 0.00% | No change | 11,086 | $41K |
| Morgan Stanley | 0.00% | Reduce -95.5% | 10,423 | $39K |
| Leonteq Securities AG | 0.00% | New | 10,000 | $37K |
| Citigroup Inc. | 0.00% | No change | 7,044 | $26K |
| Barclays PLC | 0.00% | Reduce -16.3% | 5,333 | $20K |
| TD Waterhouse Canada Inc. | 0.00% | No change | 3,203 | $11K |
| Royal Bank of Canada | 0.00% | Add +236.7% | 1,459 | $5K |
| FMR LLC | 0.00% | Reduce -98.1% | 527 | $2K |
| Osaic Holdings, Inc. | 0.00% | Reduce -3.7% | 346 | $1K |
| Coldstream Capital Management Inc. | 0.00% | New | 331 | $1K |
| Quent Capital, LLC | 0.00% | Reduce -0.7% | 231 | $864 |
| VSM Wealth Advisory, LLC | 0.00% | Reduce -0.3% | 133 | $497 |
| Mb, Levis & Associates, LLC | 0.00% | No change | 100 | $374 |
| Harbour Investments, Inc. | 0.00% | Reduce -1.9% | 85 | $318 |
| SBI Securities Co., Ltd. | 0.00% | Add +54.8% | 74 | $277 |
| Activest Wealth Management | 0.00% | Reduce -1.0% | 66 | $247 |
| Allworth Financial LP | 0.00% | Reduce -4.0% | 32 | $192 |
| Bruce G. Allen Investments, LLC | 0.00% | Reduce -2.4% | 22 | $82 |
| CIBC Private Wealth Group LLC | 0.00% | Reduce -10.0% | 3 | $12 |
| West Branch Capital LLC | 0.00% | Reduce -6.3% | 3 | $12 |
| Danske Bank A/S | 0.00% | New | 3 | $11 |
"% of holder's portfolio" is KPTI's weight in each manager's 13F, not the share of Karyopharm Therapeutics Inc. the manager owns.