Lexicon PharmaceuticalsLXRX
13F holders, Q2 2026 (June 30)149holders +13
42new positions
30sold out
7famous investors
$2.40avg. 13F price*
At the end of Q2 2026, 149 institutions reported holding Lexicon Pharmaceuticals Inc. (LXRX) in their 13F filings, up 13 from Q1 2026. 42 opened new positions and 30 sold out. The largest holders were Artal Group S.A. ($420.4M), FMR LLC ($124.3M) and Siren, L.L.C. ($106.3M). 7 famous investors held it, including Steve Cohen (0.0% of Point72 Asset Management's portfolio), Jim Simons / Peter Brown (0.0% of Renaissance Technologies's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Lexicon Pharmaceuticals Inc.
- CUSIP
- 528872302
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2026 → Q2 2026
| Institutions | Total Value | |
|---|---|---|
| New Positions | 42 | $8.3M |
| Exits | 30 | $12.5M |
All 13F filers, Q1 2026 → Q2 2026: 60,808,700 shares bought and 19,560,719 shares sold, net +41,247,981 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 149 holders
| Artal Group S.A. | 45.15% | Add +13.2% | 175,156,062 | $420.4M |
| FMR LLC | 0.01% | Add +14.9% | 51,782,045 | $124.3M |
| Siren, L.L.C. | 2.16% | No change | 44,303,518 | $106.3M |
| Sessa Capital IM, L.P. | 0.79% | Add +5.8% | 18,960,836 | $45.5M |
| BlackRock, Inc. | 0.00% | Add +422.2% | 17,348,741 | $41.6M |
| Vanguard Capital Management LLC | 0.00% | Add +4.0% | 9,901,208 | $23.8M |
| Point72 Asset Management | 0.03% | Add +5.6% | 8,251,325 | $19.8M |
| Geode Capital Management, LLC | 0.00% | Add +97.0% | 6,244,372 | $15.0M |
| State Street Corp. | 0.00% | Add +410.1% | 4,917,769 | $11.8M |
| Vanguard Portfolio Management LLC | 0.00% | Add +331.4% | 2,357,749 | $5.7M |
| Northern Trust Corp. | 0.00% | Add +298.0% | 1,968,619 | $4.7M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +49.2% | 1,956,775 | $4.7M |
| Vanguard Fiduciary Trust Co. | 0.00% | Add +22.7% | 1,634,571 | $3.9M |
| Citadel Advisors | 0.00% | Add +46.2% | 1,601,182 | $3.8M |
| Ishara Investments LP | 2.24% | Add +40.9% | 1,271,000 | $3.1M |
| Millennium Management | 0.00% | Reduce -77.1% | 1,134,229 | $2.7M |
| Renaissance Technologies | 0.00% | Reduce -29.6% | 1,127,000 | $2.7M |
| Mackenzie Financial Corp. | 0.00% | Add +24.7% | 963,354 | $2.3M |
| ADAR1 Capital Management, LLC | 0.09% | No change | 750,000 | $1.8M |
| Susquehanna International Group, LLP | 0.00% | Reduce -67.2% | 696,776 | $1.7M |
| Acadian Asset Management LLC | 0.00% | Add +56.4% | 696,617 | $1.7M |
| UBS Group AG | 0.00% | Reduce -72.4% | 684,713 | $1.6M |
| Two Sigma Investments, LP | 0.00% | Reduce -46.4% | 643,444 | $1.5M |
| Nuveen, LLC | 0.00% | New | 586,664 | $1.4M |
| Bank of New York Mellon Corp | 0.00% | Add +1971.1% | 568,706 | $1.4M |
| Invesco Ltd. | 0.00% | Reduce -0.8% | 508,071 | $1.2M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -54.6% | 485,546 | $1.2M |
| Compagnie Lombard Odier SCmA | 0.01% | Reduce -5.9% | 480,000 | $1.2M |
| Bank of America Corp. | 0.00% | Reduce -19.9% | 421,299 | $1.0M |
| Gsa Capital Partners LLP | 0.06% | Reduce -57.3% | 397,219 | $953K |
| Barclays PLC | 0.00% | Add +267.3% | 387,483 | $930K |
| XTX Topco Ltd | 0.01% | Add +13.8% | 357,877 | $859K |
| Janney Montgomery Scott LLC | 0.00% | New | 295,548 | $709K |
| Canada Pension Plan Investment Board | 0.00% | New | 257,900 | $619K |
| Rhumbline Advisers | 0.00% | Add +0.0% | 256,885 | $617K |
| Deutsche Bank AG | 0.00% | New | 247,528 | $594K |
| Wells Fargo & Company | 0.00% | Add +2870.0% | 230,470 | $553K |
| T. Rowe Price Associates Inc. | 0.00% | New | 204,391 | $491K |
| Wellington Management Group LLP | 0.00% | New | 179,700 | $431K |
| Citigroup Inc. | 0.00% | Add +5.3% | 175,205 | $420K |
| Group One Trading LLC | 0.01% | Reduce -5.4% | 175,013 | $420K |
| Virtus Investment Advisers, LLC | 0.10% | New | 170,415 | $409K |
| Headlands Technologies LLC | 0.04% | Reduce -12.6% | 167,198 | $401K |
| Ikarian Capital, LLC | 0.06% | No change | 164,674 | $395K |
| Quarry LP | 0.06% | Add +42.0% | 156,186 | $375K |
| MetLife Investment Management, LLC | 0.00% | New | 146,410 | $351K |
| Morgan Stanley | 0.00% | Reduce -39.5% | 132,902 | $319K |
| Panagora Asset Management Inc. | 0.00% | New | 132,042 | $317K |
| JPMorgan Chase & Co. | 0.00% | New | 109,839 | $290K |
| State of Wyoming | 0.03% | Add +1004.8% | 119,090 | $286K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | New | 114,114 | $274K |
| Cornerstone Investment Partners, LLC | 0.01% | New | 113,739 | $273K |
| Cerity Partners LLC | 0.00% | Reduce -10.9% | 98,400 | $236K |
| Algert Global LLC | 0.00% | New | 92,150 | $221K |
| Bank of Nova Scotia | 0.00% | Add +17.5% | 86,607 | $208K |
| LPL Financial LLC | 0.00% | Add +21.7% | 84,916 | $204K |
| Vanguard Global Advisers, LLC | 0.00% | Reduce -16.8% | 77,946 | $187K |
| AQR Capital Management | 0.00% | Reduce -21.8% | 75,230 | $181K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | New | 73,402 | $176K |
| University of Texas/Texas Am Investment Management Co. | 0.02% | Add +100.0% | 71,427 | $171K |
| Prudential Financial Inc. | 0.00% | Add +111.1% | 71,345 | $171K |
| Manufacturers Life Insurance Company, The | 0.00% | New | 69,747 | $167K |
| New York State Common Retirement Fund | 0.00% | New | 68,400 | $164K |
| Two Sigma Securities, LLC | 0.01% | New | 66,375 | $159K |
| Sei Investments Co. | 0.00% | New | 63,937 | $153K |
| Straight Path Wealth Management | 0.04% | No change | 62,666 | $150K |
| R Squared Ltd | 0.07% | Reduce -18.6% | 54,985 | $132K |
| Vanguard Personalized Indexing Management, LLC | 0.00% | Reduce -1.1% | 54,334 | $130K |
| Fortis Group Advisors, LLC | 0.02% | No change | 50,000 | $120K |
| Schonfeld Strategic Advisors LLC | 0.00% | Reduce -34.2% | 49,435 | $119K |
| Scotia Capital Inc. | 0.00% | Reduce -69.4% | 48,871 | $117K |
| Profund Advisors LLC | 0.00% | New | 48,586 | $117K |
| Voya Investment Management LLC | 0.00% | New | 47,771 | $115K |
| Axq Capital, LP | 0.01% | Add +126.9% | 45,727 | $110K |
| Boothbay Fund Management, LLC | 0.00% | No change | 44,315 | $106K |
| Alliancebernstein L.P. | 0.00% | New | 67,800 | $106K |
| WINTON GROUP Ltd | 0.00% | Add +69.4% | 43,200 | $104K |
| Intech Investment Management LLC | 0.00% | New | 42,491 | $102K |
| LMR Partners LLP | 0.00% | Add +76.3% | 41,091 | $99K |
| Bank of Montreal | 0.00% | Reduce -42.9% | 40,000 | $96K |
| BNP Paribas Financial Markets | 0.00% | Add +115.3% | 37,780 | $91K |
| Rafferty Asset Management, LLC | 0.00% | New | 34,090 | $82K |
| ProShare Advisors LLC | 0.00% | New | 32,588 | $78K |
| Leonteq Securities AG | 0.00% | No change | 30,000 | $72K |
| Pathstone Holdings, LLC | 0.00% | Add +0.7% | 29,969 | $72K |
| Pinnacle Associates Ltd. | 0.00% | No change | 29,015 | $70K |
| Security National Bank of Sioux City Iowa | 0.03% | No change | 26,650 | $64K |
| Victory Capital Management Inc. | 0.00% | Add +6.8% | 24,223 | $58K |
| Legal & General Group Plc | 0.00% | New | 24,185 | $58K |
| Xponance LLC | 0.00% | New | 23,763 | $57K |
| Graham Capital Management, L.P. | 0.00% | Reduce -30.8% | 23,541 | $56K |
| Ameritas Investment Partners, Inc. | 0.00% | New | 22,986 | $55K |
| D. E. Shaw & Co. | 0.00% | New | 22,200 | $53K |
| Quadrature Capital Ltd | 0.00% | Reduce -80.1% | 21,998 | $53K |
| Diker Management LLC | 0.04% | No change | 20,000 | $48K |
| Invera Wealth Advisors, LLC | 0.03% | No change | 20,000 | $48K |
| Wedbush Securities Inc. | 0.00% | Reduce -51.0% | 20,000 | $48K |
| Tiaa-Cref Individual & Institutional Services, LLC | 0.00% | No change | 20,000 | $48K |
| Russell Investments Group, Ltd. | 0.00% | New | 19,902 | $48K |
| Tower Research Capital LLC (TRC) | 0.00% | New | 19,486 | $47K |
| SBI Securities Co., Ltd. | 0.00% | Add +370.6% | 19,205 | $46K |
| Principal Financial Group Inc. | 0.00% | New | 19,034 | $46K |
| Credit Agricole S A | 0.00% | No change | 18,975 | $46K |
| Captrust Financial Advisors | 0.00% | Reduce -0.8% | 15,321 | $37K |
| Callan Family Office, LLC | 0.00% | No change | 14,090 | $34K |
| Truist Financial Corp. | 0.00% | No change | 14,000 | $34K |
| CIBC Bancorp USA Inc. | 0.00% | Reduce -99.2% | 13,740 | $33K |
| Gotham Asset Management | 0.00% | New | 13,627 | $33K |
| CIBC Asset Management Inc | 0.00% | Reduce -66.8% | 13,102 | $31K |
| Royal Bank of Canada | 0.00% | Add +715.6% | 12,650 | $30K |
| HBK Sorce Advisory LLC | 0.00% | No change | 11,786 | $29K |
| Squarepoint Ops LLC | 0.00% | New | 11,741 | $28K |
| Apollon Wealth Management, LLC | 0.00% | New | 11,378 | $27K |
| Mariner, LLC | 0.00% | Add +1.5% | 11,239 | $27K |
| Wealth Enhancement Advisory Services, LLC | 0.00% | Reduce -2.0% | 12,139 | $27K |
| Perennial Investment Advisors, LLC | 0.00% | No change | 10,990 | $26K |
| Cetera Investment Advisers | 0.00% | Reduce -16.7% | 10,524 | $25K |
| NBT Bank, N.A. | 0.00% | No change | 10,000 | $24K |
| Berger Financial Group, Inc | 0.00% | No change | 10,000 | $24K |
| Simplex Trading, LLC | 0.00% | New | 8,540 | $20K |
| California State Teachers Retirement System | 0.00% | New | 3,427 | $8K |
| Nisa Investment Advisors, LLC | 0.00% | No change | 2,592 | $6K |
| PNC Financial Services Group, Inc. | 0.00% | No change | 1,461 | $4K |
| Physician Wealth Advisors, Inc. | 0.00% | No change | 1,412 | $3K |
| Rialto Wealth Management, LLC | 0.00% | No change | 1,313 | $3K |
| Global Retirement Partners, LLC | 0.00% | — | 1,000 | $2K |
| Cassaday & Co Wealth Management LLC | 0.00% | No change | 1,000 | $2K |
| MassMutual Private Wealth & Trust, FSB | 0.00% | New | 957 | $2K |
| Sterling Capital Management LLC | 0.00% | New | 874 | $2K |
| Avion Wealth | 0.00% | Reduce -16.4% | 1,115 | $2K |
| Aster Capital Management (DIFC) Ltd | 0.00% | New | 743 | $2K |
| Fortitude Family Office, LLC | 0.00% | No change | 706 | $2K |
| Basecamp Wealth Advisors LLC | 0.00% | No change | 691 | $2K |
| Northwestern Mutual Wealth Management Co. | 0.00% | Reduce -0.6% | 500 | $1K |
| Steward Partners Investment Advisory, LLC | 0.00% | Reduce -20.0% | 400 | $960 |
| Jones Financial Companies LLLP | 0.00% | No change | 356 | $908 |
| Rockefeller Capital Management L.P. | 0.00% | Reduce -10.4% | 300 | $720 |
| Allworth Financial LP | 0.00% | New | 263 | $632 |
| Parallel Advisors, LLC | 0.00% | No change | 247 | $593 |
| Osaic Holdings, Inc. | 0.00% | Reduce -75.4% | 163 | $390 |
| Caitong International Asset Management Co., Ltd | 0.00% | Reduce -55.5% | 157 | $377 |
| Syntax Research, Inc. | 0.00% | No change | 142 | $341 |
| Clearstead Advisors, LLC | 0.00% | New | 100 | $240 |
| Larson Financial Group LLC | 0.00% | No change | 100 | $240 |
| Arax Advisory Partners | 0.00% | No change | 41 | $98 |
| HM Payson & Co. | 0.00% | No change | 37 | $89 |
| Blume Capital Management, Inc. | 0.00% | New | 5 | $12 |
| Farther Finance Advisors, LLC | 0.00% | Reduce -99.2% | 2 | $5 |
| Covestor Ltd | 0.00% | No change | 81 | $0 |
"% of holder's portfolio" is LXRX's weight in each manager's 13F, not the share of Lexicon Pharmaceuticals Inc. the manager owns.