Praxis Precision Medicines IPRAX
13F holders, Q4 2024 (December 31)162holders +28
33new positions
10sold out
5famous investors
$76.96avg. 13F price*
At the end of Q4 2024, 162 institutions reported holding Praxis Precision Medicines I (PRAX) in their 13F filings, up 28 from Q3 2024. 33 opened new positions and 10 sold out. The largest holders were Cormorant Asset Management, LP ($130.3M), BlackRock, Inc. ($112.5M) and Perceptive Advisors LLC ($102.3M). 5 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), Israel Englander (0.0% of Millennium Management's portfolio) and Ken Griffin (0.0% of Citadel Advisors's portfolio).
- Company
- Praxis Precision Medicines I
- CUSIP
- 74006W207
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q3 2024 → Q4 2024
| Institutions | Total Value | |
|---|---|---|
| New Positions | 33 | $47.4M |
| Exits | 10 | $12.4M |
All 13F filers, Q3 2024 → Q4 2024: 5,111,758 shares bought and 2,269,834 shares sold, net +2,841,924 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 162 holders
| Cormorant Asset Management, LP | 7.16% | Add +94.6% | 1,693,219 | $130.3M |
| BlackRock, Inc. | 0.00% | Add +12.3% | 1,462,445 | $112.5M |
| Perceptive Advisors LLC | 2.85% | Add +14.2% | 1,329,735 | $102.3M |
| T. Rowe Price Associates Inc. | 0.01% | Add +7.9% | 1,208,522 | $93.0M |
| Morgan Stanley | 0.01% | Add +1345.4% | 1,163,526 | $89.5M |
| Vanguard Group Inc. | 0.00% | Add +2.4% | 1,063,639 | $81.9M |
| Capital Research Global Investors | 0.02% | Reduce -0.3% | 993,569 | $76.5M |
| Venrock Adviser, LLC | 5.23% | Add +40.2% | 989,985 | $76.2M |
| Janus Henderson Group PLC | 0.04% | Add +77.5% | 929,523 | $71.6M |
| State Street Corp. | 0.00% | Reduce -2.7% | 768,655 | $59.2M |
| Ra Capital Management, L.P. | 0.78% | No change | 761,955 | $58.6M |
| Adage Capital Partners Gp, L.L.C. | 0.08% | Reduce -29.2% | 605,010 | $46.6M |
| Assenagon Asset Management S.A. | 0.08% | Add +5437.7% | 559,082 | $43.0M |
| Point72 Asset Management | 0.11% | Reduce -49.5% | 521,273 | $40.1M |
| Verition Fund Management LLC | 0.19% | Reduce -16.9% | 464,508 | $35.7M |
| Geode Capital Management, LLC | 0.00% | Add +2.0% | 406,711 | $31.3M |
| Franklin Resources Inc. | 0.01% | Reduce -12.4% | 389,835 | $30.0M |
| CIBC Asset Management Inc | 0.09% | Add +47.3% | 366,756 | $28.2M |
| Baker Bros. Advisors LP | 0.28% | Add +2.6% | 331,533 | $25.5M |
| Nuveen Asset Management, LLC | 0.01% | Add +0.7% | 306,911 | $23.6M |
| Kingdon Capital Management, L.L.C. | 3.99% | Reduce -17.7% | 303,000 | $23.3M |
| Velan Capital Investment Management LP | 19.92% | Reduce -14.4% | 300,000 | $23.1M |
| Goldman Sachs Group Inc. | 0.00% | Reduce -0.1% | 279,395 | $21.5M |
| Soleus Capital Management, L.P. | 1.42% | Reduce -6.1% | 243,540 | $18.7M |
| Alyeska Investment Group, L.P. | 0.07% | New | 226,788 | $17.5M |
| FMR LLC | 0.00% | Reduce -31.2% | 188,367 | $14.5M |
| 5AM Venture Management, LLC | 3.12% | Reduce -50.0% | 170,000 | $13.1M |
| Northern Trust Corp. | 0.00% | Add +10.1% | 167,590 | $12.9M |
| Driehaus Capital Management LLC | 0.10% | Reduce -0.7% | 164,912 | $12.7M |
| Susquehanna International Group, LLP | 0.02% | Add +444.7% | 157,925 | $12.2M |
| Millennium Management | 0.01% | Add +3519.4% | 150,892 | $11.6M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +4.3% | 142,892 | $11.0M |
| Stempoint Capital LP | 2.59% | Reduce -22.9% | 134,178 | $10.3M |
| UBS Group AG | 0.00% | Add +307.0% | 120,267 | $9.3M |
| PFM Health Sciences, LP | 0.72% | Reduce -34.7% | 119,509 | $9.2M |
| Norges Bank | 0.00% | Add +2278.0% | 118,900 | $9.2M |
| Candriam S.C.A. | 0.05% | Reduce -27.2% | 117,970 | $9.1M |
| Voloridge Investment Management, LLC | 0.03% | Add +54.4% | 116,062 | $8.9M |
| Polar Asset Management Partners Inc. | 0.15% | New | 98,617 | $7.6M |
| Citigroup Inc. | 0.01% | Add +14.0% | 95,047 | $7.3M |
| Citadel Advisors | 0.01% | Add +94.0% | 93,190 | $7.2M |
| Sphera Funds Management LTD. | 1.30% | Reduce -39.9% | 91,583 | $7.0M |
| Walleye Capital LLC | 0.07% | Add +61.1% | 89,613 | $6.9M |
| Invesco Ltd. | 0.00% | Reduce -19.3% | 86,983 | $6.7M |
| Alliancebernstein L.P. | 0.00% | Add +335.9% | 78,627 | $6.1M |
| Silverarc Capital Management, LLC | 1.25% | Add +8.2% | 72,516 | $5.6M |
| Acuta Capital Partners, LLC | 5.23% | Add +17.4% | 67,500 | $5.2M |
| 72 Investment Holdings, LLC | 10.33% | No change | 65,933 | $5.1M |
| Wellington Management Group LLP | 0.00% | Reduce -70.9% | 63,934 | $4.9M |
| Marshall Wace, LLP | 0.01% | Reduce -65.7% | 58,305 | $4.5M |
| TD Asset Management Inc | 0.00% | Add +20.5% | 52,898 | $4.1M |
| D. E. Shaw & Co. | 0.00% | Add +3.5% | 47,993 | $3.7M |
| Bank of New York Mellon Corp | 0.00% | Reduce -2.8% | 46,856 | $3.6M |
| First Turn Management, LLC | 0.63% | New | 45,536 | $3.5M |
| Pictet Asset Management Holding SA | 0.00% | New | 45,427 | $3.5M |
| Ally Bridge Group (NY) LLC | 2.97% | Reduce -38.5% | 44,982 | $3.5M |
| Schonfeld Strategic Advisors LLC | 0.02% | Add +51.5% | 43,100 | $3.3M |
| Simplify Asset Management Inc. | 0.23% | New | 43,085 | $3.3M |
| Jacobs Levy Equity Management, Inc. | 0.01% | No change | 39,999 | $3.1M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +9.5% | 38,483 | $3.0M |
| Barclays PLC | 0.00% | Add +0.4% | 37,288 | $2.9M |
| Tri Locum Partners LP | 0.59% | New | 37,269 | $2.9M |
| Jane Street Group, LLC | 0.00% | Reduce -3.6% | 37,144 | $2.9M |
| Rafferty Asset Management, LLC | 0.01% | Reduce -4.9% | 33,629 | $2.6M |
| Qube Research & Technologies Ltd | 0.00% | Reduce -28.4% | 31,999 | $2.5M |
| Moody Aldrich Partners LLC | 0.44% | Reduce -2.9% | 30,677 | $2.4M |
| Ensign Peak Advisors, Inc | 0.00% | New | 27,650 | $2.1M |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.05% | Reduce -31.1% | 26,503 | $2.0M |
| Swiss National Bank | 0.00% | Add +4.0% | 26,100 | $2.0M |
| Rhumbline Advisers | 0.00% | Reduce -1.5% | 22,769 | $1.8M |
| Two Sigma Investments, LP | 0.00% | Reduce -11.9% | 20,066 | $1.5M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +17.3% | 18,615 | $1.4M |
| PCG Wealth Advisors, LLC | 0.49% | Reduce -0.4% | 17,282 | $1.3M |
| Simplex Trading, LLC | 0.04% | Add +35.7% | 16,854 | $1.3M |
| American Century Companies Inc. | 0.00% | Add +51.2% | 15,594 | $1.2M |
| Deutsche Bank AG | 0.00% | Add +48.6% | 15,324 | $1.2M |
| Alps Advisors Inc. | 0.01% | Add +12.2% | 15,066 | $1.2M |
| Legal & General Group Plc | 0.00% | Add +4.4% | 14,439 | $1.1M |
| California State Teachers Retirement System | 0.00% | Add +2.2% | 12,726 | $979K |
| J. Goldman & Co LP | 0.03% | New | 11,634 | $895K |
| Jump Financial, LLC | 0.02% | New | 11,188 | $861K |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +2.4% | 11,135 | $856K |
| HighVista Strategies LLC | 0.31% | No change | 10,951 | $843K |
| State of Wisconsin Investment Board | 0.00% | Reduce -15.5% | 10,682 | $822K |
| MetLife Investment Management, LLC | 0.00% | Add +5.4% | 10,675 | $822K |
| Hussman Strategic Advisors, Inc. | 0.24% | Reduce -50.0% | 10,500 | $808K |
| Woodline Partners LP | 0.01% | New | 9,948 | $766K |
| JPMorgan Chase & Co. | 0.00% | Add +24.1% | 9,693 | $746K |
| Fred Alger Management, LLC | 0.00% | Reduce -8.9% | 9,496 | $731K |
| Trexquant Investment LP | 0.01% | Reduce -40.9% | 9,115 | $701K |
| Wells Fargo & Company | 0.00% | Add +46.8% | 8,612 | $663K |
| Corebridge Financial, Inc. | 0.00% | Reduce -7.0% | 8,574 | $660K |
| Nicholas Investment Partners, LP | 0.06% | New | 8,481 | $653K |
| Ellsworth Advisors, LLC | 0.16% | New | 8,150 | $627K |
| New York State Common Retirement Fund | 0.00% | Add +12.1% | 7,847 | $604K |
| Squarepoint Ops LLC | 0.00% | Reduce -46.9% | 7,782 | $599K |
| AQR Capital Management | 0.00% | Reduce -73.5% | 6,704 | $516K |
| Profund Advisors LLC | 0.02% | Reduce -6.9% | 6,559 | $505K |
| Intech Investment Management LLC | 0.00% | Add +68.1% | 6,338 | $488K |
| State Board of Administration of Florida Retirement System | 0.00% | Reduce -3.7% | 6,040 | $465K |
| Tower Research Capital LLC (TRC) | 0.01% | Add +565.1% | 5,873 | $452K |
| ProShare Advisors LLC | 0.00% | New | 5,738 | $442K |
| Gsa Capital Partners LLP | 0.03% | New | 5,682 | $437K |
| Bank of America Corp. | 0.00% | Reduce -89.0% | 5,504 | $424K |
| Voya Investment Management LLC | 0.00% | Reduce -7.8% | 5,228 | $402K |
| Maven Securities LTD | 0.06% | New | 5,000 | $385K |
| Aberdeen Group plc | 0.00% | No change | 4,999 | $385K |
| Sei Investments Co. | 0.00% | Add +0.6% | 4,918 | $378K |
| Dimensional Fund Advisors LP | 0.00% | Reduce -10.7% | 4,544 | $350K |
| Cerity Partners LLC | 0.00% | Reduce -0.6% | 4,364 | $334K |
| Quarry LP | 0.07% | Add +320.0% | 4,200 | $323K |
| Nomura Holdings Inc. | 0.00% | New | 4,102 | $316K |
| Mesirow Financial Investment Management, Inc. | 0.01% | Add +1.0% | 4,047 | $311K |
| Teacher Retirement System of Texas | 0.00% | New | 3,961 | $305K |
| China Universal Asset Management Co., Ltd. | 0.03% | New | 3,952 | $304K |
| Arizona State Retirement System | 0.00% | Add +4.2% | 3,851 | $296K |
| Engineers Gate Manager LP | 0.01% | Reduce -18.7% | 3,850 | $296K |
| Coastal Bridge Advisors, LLC | 0.07% | No change | 3,846 | $296K |
| Glenmede Trust Co. NA | 0.00% | Reduce -8.7% | 3,809 | $293K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | — | 3,789 | $292K |
| Pale Fire Capital SE | 0.06% | Reduce -95.0% | 3,369 | $259K |
| Ameriprise Financial Inc. | 0.00% | New | 3,227 | $248K |
| Fox Run Management, L.L.C. | 0.04% | New | 3,195 | $246K |
| Freestone Grove Partners LP | 0.00% | — | 3,080 | $237K |
| Envestnet Asset Management Inc. | 0.00% | New | 3,008 | $231K |
| Man Group plc | 0.00% | Reduce -29.9% | 2,832 | $218K |
| KLP Kapitalforvaltning As | 0.00% | — | 2,800 | $215K |
| Graham Capital Management, L.P. | 0.01% | New | 2,722 | $209K |
| BNP Paribas Financial Markets | 0.00% | Reduce -77.5% | 2,142 | $165K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,689 | $130K |
| Virtus Advisers, LLC | 0.03% | Reduce -56.4% | 1,001 | $77K |
| US Bancorp \de | 0.00% | Reduce -57.7% | 968 | $74K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | New | 621 | $48K |
| Amalgamated Bank | 0.00% | No change | 597 | $46K |
| Royal Bank of Canada | 0.00% | Reduce -74.0% | 514 | $39K |
| GF Fund Management Co. LTD. | 0.00% | — | 391 | $30K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 217 | $17K |
| Cwm, LLC | 0.00% | Add +9.6% | 195 | $15K |
| Russell Investments Group, Ltd. | 0.00% | Reduce -91.7% | 156 | $12K |
| Aster Capital Management (DIFC) Ltd | 0.00% | Add +1200.0% | 117 | $9K |
| Creative Planning | 0.00% | New | 106 | $8K |
| AlphaQuest LLC | 0.00% | New | 95 | $7K |
| R Squared Ltd | 0.01% | — | 90 | $7K |
| Osaic Holdings, Inc. | 0.00% | Add +29.5% | 79 | $6K |
| Nisa Investment Advisors, LLC | 0.00% | Add +22.4% | 71 | $5K |
| GAMMA Investing LLC | 0.00% | Add +150.0% | 65 | $5K |
| Daiwa Securities Group Inc. | 0.00% | New | 62 | $5K |
| SBI Securities Co., Ltd. | 0.00% | — | 60 | $5K |
| Bessemer Group Inc. | 0.00% | No change | 25 | $2K |
| True Wealth Design, LLC | 0.00% | No change | 25 | $2K |
| Rothschild Investment LLC | 0.00% | Add +66.7% | 25 | $2K |
| FSA Wealth Management LLC | 0.00% | No change | 21 | $2K |
| Sterling Capital Management LLC | 0.00% | No change | 18 | $1K |
| Lindbrook Capital, LLC | 0.00% | No change | 11 | $847 |
| Assetmark, Inc. | 0.00% | New | 7 | $539 |
| Principal Securities, Inc. | 0.00% | No change | 6 | $462 |
| CoreCap Advisors, LLC | 0.00% | New | 3 | $231 |
| PNC Financial Services Group, Inc. | 0.00% | New | 2 | $154 |
| Parallel Advisors, LLC | 0.00% | New | 2 | $154 |
| IFP Advisors, Inc | 0.00% | New | 1 | $77 |
| Capital Advisors, Ltd. LLC | 0.00% | No change | 2 | $0 |
| Covestor Ltd | 0.00% | New | 1 | $0 |
"% of holder's portfolio" is PRAX's weight in each manager's 13F, not the share of Praxis Precision Medicines I the manager owns.