Praxis Precision Medicines IPRAX
13F holders, Q2 2025 (June 30)143holders −7
24new positions
32sold out
4famous investors
$42.05avg. 13F price*
At the end of Q2 2025, 143 institutions reported holding Praxis Precision Medicines I (PRAX) in their 13F filings, down 7 from Q1 2025. 24 opened new positions and 32 sold out. The largest holders were Janus Henderson Group PLC ($106.5M), Adage Capital Partners Gp, L.L.C. ($83.0M) and Cormorant Asset Management, LP ($68.3M). 4 famous investors held it, including Steve Cohen (0.1% of Point72 Asset Management's portfolio), David E. Shaw (0.0% of D. E. Shaw & Co.'s portfolio) and Cliff Asness (0.0% of AQR Capital Management's portfolio).
- Company
- Praxis Precision Medicines I
- CUSIP
- 74006W207
- Latest filing quarter
- Q2 2026
History
Number of 13F holders
Total Exit/New Position Q1 2025 → Q2 2025
| Institutions | Total Value | |
|---|---|---|
| New Positions | 24 | $24.9M |
| Exits | 32 | $91.1M |
All 13F filers, Q1 2025 → Q2 2025: 4,750,991 shares bought and 4,051,340 shares sold, net +699,651 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.
Ownership 143 holders
| Janus Henderson Group PLC | 0.05% | Add +68.2% | 2,533,405 | $106.5M |
| Adage Capital Partners Gp, L.L.C. | 0.14% | Add +13.3% | 1,974,585 | $83.0M |
| Cormorant Asset Management, LP | 5.09% | Reduce -6.9% | 1,625,000 | $68.3M |
| BlackRock, Inc. | 0.00% | Add +12.2% | 1,590,128 | $66.9M |
| T. Rowe Price Associates Inc. | 0.01% | Add +34.4% | 1,473,075 | $61.9M |
| Morgan Stanley | 0.00% | Add +1.0% | 1,226,339 | $51.6M |
| Vanguard Group Inc. | 0.00% | Add +11.8% | 1,215,644 | $51.1M |
| Soleus Capital Management, L.P. | 2.81% | Reduce -15.2% | 966,740 | $40.7M |
| Point72 Asset Management | 0.10% | Add +186.1% | 954,075 | $40.1M |
| Perceptive Advisors LLC | 1.19% | Reduce -23.2% | 752,921 | $31.7M |
| State Street Corp. | 0.00% | Reduce -5.3% | 698,093 | $29.4M |
| Baker Bros. Advisors LP | 0.28% | Add +108.0% | 689,488 | $29.0M |
| Deerfield Management Company, L.P. | 0.59% | Add +10.8% | 686,931 | $28.9M |
| Assenagon Asset Management S.A. | 0.04% | Add +19.1% | 604,298 | $25.4M |
| Driehaus Capital Management LLC | 0.18% | Add +10.3% | 530,988 | $22.3M |
| Bank of America Corp. | 0.00% | Reduce -1.6% | 453,403 | $19.1M |
| Geode Capital Management, LLC | 0.00% | Add +8.1% | 451,731 | $19.0M |
| CIBC Asset Management Inc | 0.05% | No change | 388,759 | $16.3M |
| Balyasny Asset Management L.P. | 0.04% | Reduce -8.4% | 369,254 | $15.5M |
| Franklin Resources Inc. | 0.00% | Add +0.0% | 314,150 | $13.2M |
| Ikarian Capital, LLC | 3.85% | Add +90.3% | 276,950 | $11.6M |
| Goldman Sachs Group Inc. | 0.00% | Add +27.5% | 225,992 | $9.5M |
| Logos Global Management LP | 1.26% | New | 225,000 | $9.5M |
| Aberdeen Group plc | 0.02% | Add +143.5% | 214,056 | $9.0M |
| Northern Trust Corp. | 0.00% | Add +29.4% | 213,712 | $9.0M |
| Tri Locum Partners LP | 2.49% | Add +133.6% | 195,432 | $8.2M |
| 5AM Venture Management, LLC | 2.75% | No change | 170,000 | $7.1M |
| Vivo Capital, LLC | 0.72% | New | 167,600 | $7.0M |
| Charles Schwab Investment Management Inc. | 0.00% | Add +8.1% | 152,444 | $6.4M |
| Velan Capital Investment Management LP | 6.28% | Reduce -19.3% | 149,334 | $6.3M |
| Alyeska Investment Group, L.P. | 0.02% | Reduce -16.7% | 125,000 | $5.3M |
| Verition Fund Management LLC | 0.03% | Reduce -40.7% | 118,482 | $5.0M |
| Boothbay Fund Management, LLC | 0.16% | Add +153.3% | 118,121 | $5.0M |
| Sphera Funds Management LTD. | 1.21% | Reduce -22.0% | 109,757 | $4.6M |
| Schonfeld Strategic Advisors LLC | 0.03% | Add +1557.9% | 100,702 | $4.2M |
| UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 0.00% | Add +11.3% | 96,945 | $4.1M |
| Barclays PLC | 0.00% | Add +179.3% | 88,724 | $3.7M |
| UBS Group AG | 0.00% | Reduce -55.1% | 86,534 | $3.6M |
| PFM Health Sciences, LP | 0.32% | Reduce -47.3% | 84,713 | $3.6M |
| Ally Bridge Group (NY) LLC | 2.83% | Reduce -15.4% | 80,880 | $3.4M |
| Pictet Asset Management Holding SA | 0.00% | Add +0.7% | 79,143 | $3.3M |
| Acuta Capital Partners, LLC | 4.35% | Reduce -15.0% | 74,087 | $3.1M |
| Kennedy Capital Management LLC | 0.07% | Add +7.9% | 70,445 | $3.0M |
| HighVista Strategies LLC | 1.04% | Add +71.3% | 67,288 | $2.8M |
| 72 Investment Holdings, LLC | 7.23% | No change | 65,933 | $2.8M |
| TD Asset Management Inc | 0.00% | Add +72.2% | 63,938 | $2.7M |
| Candriam S.C.A. | 0.02% | No change | 63,671 | $2.7M |
| Exome Asset Management LLC | 2.05% | New | 59,002 | $2.5M |
| Manufacturers Life Insurance Company, The | 0.00% | Add +72.8% | 56,131 | $2.4M |
| Wellington Management Group LLP | 0.00% | Add +10.1% | 55,881 | $2.3M |
| Bank of New York Mellon Corp | 0.00% | Add +13.5% | 52,553 | $2.2M |
| Susquehanna International Group, LLP | 0.00% | Add +35.0% | 46,927 | $2.0M |
| Woodline Partners LP | 0.01% | Reduce -73.8% | 45,952 | $1.9M |
| Jacobs Levy Equity Management, Inc. | 0.01% | Add +12.7% | 45,082 | $1.9M |
| Caption Management, LLC | 0.15% | Add +113.5% | 39,036 | $1.6M |
| Nuveen, LLC | 0.00% | Add +161.1% | 38,549 | $1.6M |
| FMR LLC | 0.00% | Add +6.7% | 38,100 | $1.6M |
| B Group, Inc. | 1.27% | Add +84.2% | 35,000 | $1.5M |
| Stempoint Capital LP | 0.44% | New | 32,255 | $1.4M |
| Swiss National Bank | 0.00% | Add +13.7% | 30,800 | $1.3M |
| Algert Global LLC | 0.02% | Add +28.3% | 27,570 | $1.2M |
| Rhumbline Advisers | 0.00% | Add +12.5% | 27,341 | $1.1M |
| Simplex Trading, LLC | 0.03% | Add +668.0% | 25,328 | $1.1M |
| Rafferty Asset Management, LLC | 0.00% | Reduce -15.2% | 24,805 | $1.0M |
| Capital Fund Management S.A. | 0.01% | New | 24,292 | $1.0M |
| MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. | 0.00% | Add +103.9% | 23,873 | $1.0M |
| Royal Bank of Canada | 0.00% | Add +20819.4% | 22,593 | $950K |
| OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) | 0.03% | Reduce -18.3% | 21,892 | $921K |
| Prelude Capital Management, LLC | 0.08% | New | 19,900 | $837K |
| D. E. Shaw & Co. | 0.00% | Add +56.1% | 19,056 | $801K |
| Alliancebernstein L.P. | 0.00% | Reduce -64.7% | 18,040 | $759K |
| Legal & General Group Plc | 0.00% | Add +15.7% | 16,670 | $701K |
| California State Teachers Retirement System | 0.00% | No change | 16,346 | $687K |
| Invesco Ltd. | 0.00% | Add +36.5% | 15,939 | $670K |
| Sofinnova Investments, Inc. | 0.04% | Reduce -90.0% | 15,717 | $661K |
| State of Wisconsin Investment Board | 0.00% | Add +1.0% | 14,759 | $621K |
| AQR Capital Management | 0.00% | New | 14,580 | $613K |
| JPMorgan Chase & Co. | 0.00% | Add +21.4% | 13,938 | $586K |
| Jane Street Group, LLC | 0.00% | Add +37.0% | 13,003 | $547K |
| Deutsche Bank AG | 0.00% | Reduce -12.5% | 12,124 | $510K |
| Gsa Capital Partners LLP | 0.04% | Reduce -7.5% | 12,008 | $505K |
| Citigroup Inc. | 0.00% | Reduce -74.0% | 11,866 | $499K |
| Wells Fargo & Company | 0.00% | Add +32.1% | 11,252 | $473K |
| Alps Advisors Inc. | 0.00% | Reduce -26.4% | 10,994 | $462K |
| MetLife Investment Management, LLC | 0.00% | Reduce -0.7% | 10,520 | $442K |
| Hussman Strategic Advisors, Inc. | 0.10% | No change | 10,500 | $442K |
| Citadel Advisors | 0.00% | Reduce -83.3% | 10,366 | $436K |
| Silverarc Capital Management, LLC | 0.09% | Reduce -94.0% | 10,000 | $421K |
| Intech Investment Management LLC | 0.00% | Reduce -0.9% | 8,719 | $367K |
| Brevan Howard Capital Management LP | 0.00% | New | 8,503 | $358K |
| New York State Common Retirement Fund | 0.00% | No change | 6,600 | $278K |
| Two Sigma Investments, LP | 0.00% | Reduce -65.4% | 6,509 | $274K |
| Creative Planning | 0.00% | New | 6,495 | $273K |
| State Board of Administration of Florida Retirement System | 0.00% | Add +6.4% | 6,425 | $270K |
| Susquehanna Portfolio Strategies, LLC | 0.01% | New | 5,750 | $242K |
| Cerity Partners LLC | 0.00% | New | 5,611 | $236K |
| Profund Advisors LLC | 0.01% | Reduce -13.9% | 5,261 | $221K |
| Virtu Financial LLC | 0.01% | New | 5,058 | $213K |
| Maven Securities LTD | 0.05% | New | 5,000 | $210K |
| Jefferies Financial Group Inc. | 0.00% | New | 5,000 | $210K |
| Norges Bank | 0.00% | Reduce -94.1% | 5,000 | $210K |
| Voya Investment Management LLC | 0.00% | New | 4,919 | $207K |
| Quarry LP | 0.05% | Add +23.1% | 4,800 | $202K |
| China Universal Asset Management Co., Ltd. | 0.02% | Add +1.2% | 4,091 | $172K |
| Police & Firemen's Retirement System of New Jersey | 0.00% | No change | 3,789 | $159K |
| Toronto Dominion Bank | 0.00% | New | 3,100 | $130K |
| KLP Kapitalforvaltning As | 0.00% | No change | 2,800 | $118K |
| Virtus Investment Advisers, LLC | 0.03% | Reduce -9.8% | 2,088 | $88K |
| BNP Paribas Financial Markets | 0.00% | Reduce -72.5% | 2,047 | $86K |
| Tower Research Capital LLC (TRC) | 0.00% | Add +24.3% | 1,837 | $77K |
| Ameritas Investment Partners, Inc. | 0.00% | No change | 1,689 | $71K |
| Mirae Asset Global Investments Co., Ltd. | 0.00% | Add +16.6% | 787 | $33K |
| Cwm, LLC | 0.00% | Add +877.9% | 753 | $32K |
| Nisa Investment Advisors, LLC | 0.00% | Add +88.3% | 629 | $26K |
| Amalgamated Bank | 0.00% | No change | 599 | $25K |
| GF Fund Management Co. LTD. | 0.00% | No change | 477 | $20K |
| Sterling Capital Management LLC | 0.00% | Add +2372.2% | 445 | $19K |
| Brooklyn Investment Group | 0.00% | New | 298 | $13K |
| Russell Investments Group, Ltd. | 0.00% | New | 249 | $10K |
| Farther Finance Advisors, LLC | 0.00% | Add +15.0% | 230 | $10K |
| Caitong International Asset Management Co., Ltd | 0.01% | New | 219 | $9K |
| Public Employees Retirement Association of Colorado | 0.00% | No change | 217 | $9K |
| Zurcher Kantonalbank (Zurich Cantonalbank) | 0.00% | No change | 167 | $7K |
| US Bancorp \de | 0.00% | Reduce -80.8% | 166 | $7K |
| GAMMA Investing LLC | 0.00% | Add +46.2% | 155 | $7K |
| BNP PARIBAS ASSET MANAGEMENT Holding S.A. | 0.00% | New | 133 | $6K |
| AlphaQuest LLC | 0.00% | Reduce -21.6% | 116 | $5K |
| SBI Securities Co., Ltd. | 0.00% | Add +15.4% | 75 | $3K |
| Daiwa Securities Group Inc. | 0.00% | No change | 62 | $3K |
| Allworth Financial LP | 0.00% | Add +1050.0% | 69 | $3K |
| Osaic Holdings, Inc. | 0.00% | Reduce -18.2% | 54 | $2K |
| Rothschild Investment LLC | 0.00% | Add +900.0% | 50 | $2K |
| Larson Financial Group LLC | 0.00% | New | 38 | $2K |
| PNC Financial Services Group, Inc. | 0.00% | Add +380.0% | 24 | $1K |
| Hemington Wealth Management | 0.00% | No change | 30 | $1K |
| Arax Advisory Partners | 0.00% | New | 23 | $968 |
| FSA Wealth Management LLC | 0.00% | No change | 21 | $883 |
| EverSource Wealth Advisors, LLC | 0.00% | Add +63.6% | 18 | $757 |
| Parkside Financial Bank & Trust | 0.00% | No change | 10 | $421 |
| Twin Peaks Wealth Advisors, LLC | 0.00% | New | 1 | $48 |
| National Bank of Canada | 0.00% | New | 1 | $42 |
| Essential Partners LLC | 0.00% | — | 1 | $42 |
| Covestor Ltd | 0.00% | Add +100.0% | 2 | $0 |
"% of holder's portfolio" is PRAX's weight in each manager's 13F, not the share of Praxis Precision Medicines I the manager owns.