Praxis Precision Medicines IPRAX

13F holders, Q1 2026 (March 31)
291holders +41
72new positions
30sold out
2famous investors
$321.97avg. 13F price*

At the end of Q1 2026, 291 institutions reported holding Praxis Precision Medicines I (PRAX) in their 13F filings, up 41 from Q4 2025. 72 opened new positions and 30 sold out. The largest holders were Janus Henderson Group PLC ($1.1B), Orbis Allan Gray Ltd ($796.6M) and BlackRock, Inc. ($749.1M). 2 famous investors held it, including Cliff Asness (0.0% of AQR Capital Management's portfolio) and Israel Englander (0.0% of Millennium Management's portfolio).

Company
Praxis Precision Medicines I
CUSIP
74006W207
Latest filing quarter
Q2 2026

History

Number of 13F holders

0100200300400 Q1 2024: 111Q1 2024Q2 2024: 113Q2 2024Q3 2024: 134Q3 2024Q4 2024: 162Q4 2024Q1 2025: 150Q1 2025Q2 2025: 143Q2 2025Q3 2025: 152Q3 2025Q4 2025: 250Q4 2025Q1 2026: 291Q1 2026Q2 2026: 309Q2 2026

Total Exit/New Position Q4 2025 → Q1 2026

InstitutionsTotal Value
New Positions72$75.0M
Exits30$358.2M

All 13F filers, Q4 2025 → Q1 2026: 4,667,433 shares bought and 3,064,233 shares sold, net +1,603,200 shares. Counts holders who added, trimmed, opened or closed a position; split-adjusted.

Ownership 291 holders

Janus Henderson Group PLC 0.53% Add +6.8% 3,458,863 $1.1B
Orbis Allan Gray Ltd 3.36% Add +97.0% 2,472,480 $796.6M
BlackRock, Inc. 0.01% Add +11.9% 2,324,929 $749.1M
FMR LLC 0.04% Add +59.0% 2,160,943 $696.2M
Perceptive Advisors LLC 13.00% Add +2.0% 2,035,986 $656.0M
Baker Bros. Advisors LP 3.24% Add +55.6% 1,753,198 $564.9M
Vanguard Capital Management LLC 0.01% — 1,221,944 $393.7M
Deerfield Management Company, L.P. 4.33% Add +6.6% 963,351 $310.4M
Driehaus Capital Management LLC 2.25% Add +1.7% 949,225 $305.8M
Cormorant Asset Management, LP 14.38% Reduce -6.8% 885,500 $285.3M
State Street Corp. 0.01% Add +0.2% 884,238 $284.9M
Morgan Stanley 0.02% Reduce -6.3% 833,491 $268.5M
Adage Capital Partners Gp, L.L.C. 0.41% Reduce -15.5% 815,739 $262.8M
Vanguard Portfolio Management LLC 0.01% — 756,748 $243.8M
Goldman Sachs Group Inc. 0.03% Reduce -0.8% 710,734 $229.0M
Geode Capital Management, LLC 0.01% Add +15.7% 650,904 $209.8M
T. Rowe Price Associates Inc. 0.02% Reduce -19.7% 630,852 $203.3M
Bank of America Corp. 0.01% Add +2.3% 534,604 $172.2M
Ra Capital Management, L.P. 1.28% No change 373,787 $120.4M
Hood River Capital Management LLC 1.16% Add +23.9% 358,618 $115.5M
Vivo Capital, LLC 9.08% Add +3.0% 338,895 $109.2M
Soleus Capital Management, L.P. 4.31% Reduce -8.9% 330,517 $106.5M
Logos Global Management LP 4.73% Reduce -24.0% 285,000 $91.8M
Pictet Asset Management Holding SA 0.10% Add +19.1% 286,644 $91.4M
Franklin Resources Inc. 0.02% Reduce -22.4% 276,123 $89.0M
Northern Trust Corp. 0.01% Add +18.5% 227,934 $73.4M
Charles Schwab Investment Management Inc. 0.01% Add +8.7% 215,447 $69.4M
Woodline Partners LP 0.24% Add +89.7% 200,013 $64.4M
T. Rowe Price Investment Management, Inc. 0.04% Reduce -36.6% 175,237 $56.5M
Wellington Management Group LLP 0.01% Reduce -1.3% 174,350 $56.2M
Orbimed Advisors LLC 1.26% Add +82.5% 172,500 $55.6M
Aberdeen Group plc 0.09% Add +27.8% 172,484 $55.6M
Affinity Asset Advisors, LLC 3.28% Reduce -8.1% 170,000 $54.8M
Vanguard Fiduciary Trust Co. 0.01% — 169,902 $54.7M
BNP Paribas Financial Markets 0.03% Add +2993.0% 143,082 $46.1M
American Century Companies Inc. 0.02% Add +70.2% 128,254 $41.3M
Qube Research & Technologies Ltd 0.06% Reduce -24.1% 128,228 $41.3M
ArrowMark Colorado Holdings LLC 1.01% Add +292.8% 117,851 $38.0M
UBS Group AG 0.01% Add +21.6% 108,446 $34.9M
Velan Capital Investment Management LP 20.34% No change 100,781 $32.5M
Bank of New York Mellon Corp 0.01% Add +11.8% 87,047 $28.0M
Acuta Capital Partners, LLC 19.46% Add +2.3% 84,901 $27.4M
MetLife Investment Management, LLC 0.13% Add +551.4% 80,930 $26.1M
Alyeska Investment Group, L.P. 0.07% Reduce -3.0% 72,178 $23.3M
Nuveen, LLC 0.01% Add +44.2% 72,043 $23.2M
Ikarian Capital, LLC 3.30% Reduce -17.3% 71,581 $23.1M
Silverarc Capital Management, LLC 2.72% Reduce -13.2% 71,552 $23.1M
JPMorgan Chase & Co. 0.00% Add +45.0% 80,180 $22.2M
Ensign Peak Advisors, Inc 0.04% Add +6.4% 68,383 $22.0M
72 Investment Holdings, LLC 42.83% No change 65,933 $21.2M
Sofinnova Investments, Inc. 1.03% Reduce -49.4% 63,680 $20.5M
Candriam S.C.A. 0.11% Reduce -42.5% 63,628 $20.5M
Invesco Ltd. 0.00% Reduce -20.4% 61,397 $19.8M
AQR Capital Management 0.01% Add +103.5% 58,656 $18.9M
Deutsche Bank AG 0.01% Add +13.7% 57,779 $18.6M
Stempoint Capital LP 3.48% Add +167.1% 56,267 $18.1M
Frontier Capital Management Co. LLC 0.18% New 53,365 $17.2M
Universal- Beteiligungs- und Servicegesellschaft mbH 0.03% Add +26.9% 47,432 $15.3M
Swiss National Bank 0.01% Add +15.3% 46,700 $15.0M
Boxer Capital Management, LLC 1.97% No change 46,457 $15.0M
Exome Asset Management LLC 8.62% Reduce -21.8% 45,469 $14.6M
Marshall Wace, LLP 0.02% Reduce -34.8% 45,149 $14.5M
KVP Capital Advisors, LP 10.32% No change 42,900 $13.8M
First Turn Management, LLC 1.53% Add +18.7% 42,441 $13.7M
California Public Employees Retirement System 0.01% New 42,163 $13.6M
Canada Pension Plan Investment Board 0.01% Reduce -42.4% 40,130 $12.9M
Integral Health Asset Management, LLC 0.68% No change 40,000 $12.9M
Eventide Asset Management, LLC 0.21% Reduce -42.4% 38,640 $12.4M
UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC 0.00% Add +8.1% 38,145 $12.3M
SummitTX Capital, L.P. 0.38% Reduce -11.5% 36,838 $11.9M
PFM Health Sciences, LP 1.22% Add +13.7% 35,438 $11.4M
TD Asset Management Inc 0.01% Reduce -23.8% 35,146 $11.3M
Burkehill Global Management, LP 0.59% Add +40.0% 35,000 $11.3M
First Trust Advisors LP 0.01% Reduce -62.4% 33,335 $10.7M
B Group, Inc. 7.94% No change 33,237 $10.7M
Rhumbline Advisers 0.01% Add +16.1% 32,879 $10.6M
Ally Bridge Group (NY) LLC 10.50% Add +65.0% 32,810 $10.6M
Ameriprise Financial Inc. 0.00% Add +37.4% 31,220 $10.1M
Dimensional Fund Advisors LP 0.00% Add +32.4% 31,161 $10.0M
Prudential Financial Inc. 0.01% Add +105.3% 30,510 $9.8M
Manufacturers Life Insurance Company, The 0.01% Reduce -9.6% 30,093 $9.7M
Lord, Abbett & Co. LLC 0.03% Reduce -3.7% 29,619 $9.5M
Sei Investments Co. 0.01% Add +86.9% 29,525 $9.5M
Voya Investment Management LLC 0.01% Add +106.0% 28,134 $9.1M
MIRAE ASSET GLOBAL ETFS HOLDINGS Ltd. 0.01% Add +8.6% 27,744 $8.9M
California State Teachers Retirement System 0.01% Add +39.7% 27,477 $8.9M
HighVista Strategies LLC 2.34% Add +1.9% 26,323 $8.5M
Neuberger Berman Group LLC 0.01% Add +1.1% 25,960 $8.4M
Alliancebernstein L.P. 0.00% Add +10.5% 27,700 $8.2M
University of Wisconsin Foundation 7.21% New 25,215 $8.1M
Congress Asset Management Co. 0.06% Reduce -20.5% 24,839 $8.0M
Susquehanna Portfolio Strategies, LLC 0.11% No change 23,251 $7.5M
Russell Investments Group, Ltd. 0.01% Add +12.1% 23,112 $7.4M
Ishara Investments LP 7.34% Reduce -43.6% 22,550 $7.3M
VANGUARD ASSET MANAGEMENT, Ltd 0.01% — 22,000 $7.1M
Moody Aldrich Partners LLC 1.26% Reduce -48.0% 21,688 $7.0M
Atom Investors LP 0.49% Add +28.6% 21,196 $6.8M
Informed Momentum Co LLC 0.71% Reduce -9.3% 18,995 $6.1M
Legal & General Group Plc 0.00% Add +2.8% 18,482 $6.0M
Two Sigma Investments, LP 0.00% Reduce -23.8% 17,598 $5.7M
Boothbay Fund Management, LLC 0.14% Reduce -16.1% 17,587 $5.7M
Creative Planning 0.00% Add +50.2% 16,286 $5.2M
Algert Global LLC 0.08% Reduce -80.0% 16,168 $5.2M
Tetragon Partners GP Ltd 1.01% Reduce -30.5% 15,952 $5.1M
J. Goldman & Co LP 0.23% Add +182.2% 15,664 $5.0M
Rafferty Asset Management, LLC 0.02% Reduce -31.7% 15,188 $4.9M
ExodusPoint Capital Management, LP 0.05% New 14,742 $4.7M
State of Wisconsin Investment Board 0.01% Reduce -3.9% 14,642 $4.7M
Victory Capital Management Inc. 0.00% Add +6.3% 14,132 $4.6M
Allianz Asset Management GmbH 0.01% Add +484.6% 14,030 $4.5M
Mutual of America Capital Management LLC 0.05% New 12,473 $4.0M
Wells Fargo & Company 0.00% Reduce -54.0% 11,614 $3.7M
Vanguard Global Advisers, LLC 0.00% — 11,335 $3.7M
Polen Capital Management LLC 0.02% New 10,043 $3.2M
Braidwell LP 0.12% New 9,976 $3.2M
Prelude Capital Management, LLC 0.22% Reduce -43.5% 9,064 $2.9M
Erste Asset Management GmbH 0.03% No change 10,500 $2.9M
New York State Common Retirement Fund 0.00% Add +19.9% 8,749 $2.8M
Susquehanna International Group, LLP 0.00% Add +263.5% 8,517 $2.7M
Allspring Global Investments Holdings, LLC 0.00% Add +392.8% 8,536 $2.7M
State of New Jersey Common Pension Fund D 0.01% Add +14.8% 8,058 $2.6M
Massachusetts Financial Services Co. 0.00% Add +122.8% 7,388 $2.4M
Connor, Clark & Lunn Investment Management Ltd. 0.01% Add +4.7% 7,194 $2.3M
Profund Advisors LLC 0.08% Reduce -16.3% 7,081 $2.3M
Police & Firemen's Retirement System of New Jersey 0.02% Add +15.4% 6,989 $2.3M
Barclays PLC 0.00% Reduce -98.7% 6,979 $2.2M
Intech Investment Management LLC 0.02% Reduce -20.1% 6,977 $2.2M
Vestmark Advisory Solutions, Inc. 0.02% Add +48.3% 6,681 $2.2M
Trexquant Investment LP 0.02% Reduce -20.5% 6,626 $2.1M
Arizona State Retirement System 0.01% Add +13.2% 6,476 $2.1M
Nisa Investment Advisors, LLC 0.01% Reduce -19.2% 6,280 $2.0M
Vanguard Investments Australia, Ltd. 0.01% — 5,936 $1.9M
State Board of Administration of Florida Retirement System 0.00% Add +1.6% 5,902 $1.9M
Citigroup Inc. 0.00% Add +1.1% 5,646 $1.8M
Raymond James Financial Inc. 0.00% Add +1.6% 5,320 $1.7M
KLP Kapitalforvaltning As 0.01% Add +18.2% 5,200 $1.7M
Los Angeles Capital Management LLC 0.01% Add +816.7% 5,060 $1.6M
Ghisallo Capital Management LLC 0.04% New 5,000 $1.6M
ProShare Advisors LLC 0.00% Reduce -4.3% 4,988 $1.6M
China Universal Asset Management Co., Ltd. 0.12% Add +1.4% 4,942 $1.6M
Envestnet Asset Management Inc. 0.00% Reduce -12.4% 4,862 $1.6M
Lion Point Capital, LP 8.57% No change 4,450 $1.4M
Hussman Strategic Advisors, Inc. 0.29% Reduce -50.0% 4,200 $1.4M
Royal Bank of Canada 0.00% Add +22.4% 4,133 $1.3M
Zurcher Kantonalbank (Zurich Cantonalbank) 0.00% Add +4031.6% 4,049 $1.3M
Nicholas Investment Partners, LP 0.10% New 3,948 $1.3M
Coastal Bridge Advisors, LLC 0.09% Reduce -6.0% 3,906 $1.3M
Arrowpoint Investment Partners (Singapore) Pte. Ltd. 1.85% Add +85.2% 3,855 $1.2M
Millennium Management 0.00% New 3,831 $1.2M
STRS Ohio 0.00% Add +12.5% 3,600 $1.2M
Fifth Third Bancorp 0.00% New 3,589 $1.2M
Allstate Corp. 0.01% New 3,512 $1.1M
Glenmede Trust Co. NA 0.01% Reduce -45.8% 3,410 $1.1M
FORA Capital, LLC 0.08% New 3,412 $1.1M
Quantinno Capital Management LP 0.00% Add +21.9% 3,320 $1.1M
Homestead Advisers Corp 0.03% New 3,300 $1.1M
Man Group plc 0.00% Reduce -85.0% 3,173 $1.0M
Teacher Retirement System of Texas 0.00% Add +0.3% 3,062 $987K
LPL Financial LLC 0.00% New 2,923 $942K
Quarry LP 0.18% Reduce -31.3% 2,750 $886K
Act Capital Management, LLC 0.68% Add +285.7% 2,700 $870K
Guggenheim Capital LLC 0.01% New 2,670 $860K
Artia Global Partners LP 0.18% No change 2,500 $805K
Xponance LLC 0.01% Add +37.2% 2,420 $780K
Public Employees Retirement Association of Colorado 0.00% No change 2,390 $770K
Ameritas Investment Partners, Inc. 0.02% Add +13.2% 2,113 $681K
Squarepoint Ops LLC 0.00% Add +6.3% 2,010 $648K
Ethic Inc. 0.01% Reduce -9.3% 1,990 $641K
E Fund Management Co., Ltd. 0.02% — 1,956 $630K
Mercer Global Advisors Inc. 0.00% Add +52.6% 1,850 $596K
Amundi 0.00% Add +128.1% 1,802 $581K
VIRGINIA RETIREMENT SYSTEMS ET Al 0.00% Reduce -48.6% 1,800 $580K
Bellevue Group AG 0.01% New 1,757 $566K
Orion Porfolio Solutions, LLC 0.00% Reduce -12.6% 1,734 $559K
Simplex Trading, LLC 0.02% New 1,660 $535K
Hudson Bay Capital Management LP 0.00% New 1,640 $528K
Martingale Asset Management L P 0.01% Add +52.9% 1,615 $520K
HSBC Holdings PLC 0.00% Add +98.1% 1,634 $518K
Cerity Partners LLC 0.00% Reduce -59.3% 1,599 $515K
US Bancorp \de 0.00% Reduce -15.7% 1,539 $496K
Centiva Capital, LP 0.02% New 1,501 $484K
PSP Research LLC 0.34% Reduce -24.3% 1,500 $483K
ADAR1 Capital Management, LLC 0.03% No change 1,500 $483K
StoneX Group Inc. 0.03% Reduce -16.8% 1,469 $473K
Mirae Asset Global Investments Co., Ltd. 0.00% Add +19.6% 1,453 $468K
Cwm, LLC 0.00% Add +63.8% 1,432 $461K
Swiss Life Asset Management Ltd 0.00% Add +48.2% 1,402 $452K
Abel Hall, LLC 0.10% Add +34.9% 1,392 $448K
XTX Topco Ltd 0.01% New 1,344 $433K
Vanguard Personalized Indexing Management, LLC 0.00% New 1,344 $433K
Tower Research Capital LLC (TRC) 0.01% Add +118.2% 1,333 $429K
CIBC Bancorp USA Inc. 0.00% — 1,312 $423K
Integrated Quantitative Investments LLC 0.07% New 1,253 $404K
Fieldview Capital Management, LLC 0.12% New 1,223 $394K
Fox Run Management, L.L.C. 0.07% New 1,393 $385K
Mariner, LLC 0.00% New 1,177 $379K
Principal Financial Group Inc. 0.00% Add +15.9% 1,153 $371K
DNB Asset Management AS 0.00% New 1,146 $369K
AlphaGrep UK Ltd 0.11% New 1,134 $365K
Persistent Asset Partners Ltd 0.14% Reduce -19.6% 1,131 $364K
Atria Investments, Inc 0.00% New 1,060 $342K
Virtus Investment Advisers, LLC 0.09% Add +2.4% 1,013 $326K
QP Wealth Management, LLC 0.55% New 995 $321K
Gallagher Fiduciary Advisors, LLC 0.01% New 990 $319K
Carl P. Sherr & Co., LLC 0.15% Add +8.4% 972 $313K
Brevan Howard Capital Management LP 0.00% New 972 $313K
Brick & Kyle, Associates 0.10% New 966 $311K
PNC Financial Services Group, Inc. 0.00% Add +33.5% 953 $307K
Daiwa Securities Group Inc. 0.00% Add +1213.9% 946 $305K
M&T Bank Corp 0.00% Add +5.7% 935 $301K
CTC Alternative Strategies, Ltd. 0.68% New 925 $298K
CIBC Asset Management Inc 0.00% No change 900 $290K
Chicago Partners Investment Group LLC 0.01% New 833 $281K
Inscription Capital, LLC 0.03% No change 866 $279K
SG Americas Securities, LLC 0.00% Reduce -91.5% 852 $275K
Ieq Capital, LLC 0.00% Add +3.3% 842 $271K
O'shaughnessy Asset Management, LLC 0.00% Add +9.2% 839 $270K
GTS Securities LLC 0.01% New 837 $270K
Sterling Capital Management LLC 0.00% Reduce -33.6% 804 $259K
Bank of Montreal 0.00% New 804 $259K
Perbak Capital Partners LLP 0.06% New 799 $257K
Englebert Financial Advisers, LLC 0.29% New 789 $254K
Wealth Enhancement Advisory Services, LLC 0.00% New 787 $244K
Pinnacle Wealth Management Advisory Group, LLC 0.02% New 744 $240K
Pinnacle Associates Ltd. 0.00% New 744 $240K
Acadian Asset Management LLC 0.00% Add +17.8% 741 $238K
KBC Group NV 0.00% Add +5.8% 715 $230K
Amalgamated Bank 0.00% No change 708 $228K
Legato Capital Management LLC 0.02% New 670 $216K
Scientech Research LLC 0.18% New 669 $216K
Lanark Financial, Inc. 0.02% Add +413.9% 668 $215K
Westfield Capital Management Co. LP 0.00% New 662 $213K
Commonwealth Equity Services, LLC 0.00% Reduce -11.4% 660 $213K
MML Investors Services, LLC 0.00% Reduce -26.0% 639 $206K
GF Fund Management Co. LTD. 0.00% Add +14.7% 562 $181K
Caitong International Asset Management Co., Ltd 0.03% New 472 $152K
BNP PARIBAS ASSET MANAGEMENT Holding S.A. 0.00% Add +52.0% 424 $137K
ABS Direct Equity Fund LLC 0.10% New 400 $135K
Rockefeller Capital Management L.P. 0.00% Add +392.2% 315 $101K
GAMMA Investing LLC 0.00% Add +26.5% 301 $97K
Toronto Dominion Bank 0.00% New 289 $93K
Eurizon Capital SGR S.p.A. 0.00% New 306 $85K
Farther Finance Advisors, LLC 0.00% Reduce -35.3% 238 $76K
Kemnay Advisory Services Inc. 0.01% Add +262.3% 221 $71K
Group One Trading LLC 0.00% Reduce -97.7% 129 $42K
Parallel Advisors, LLC 0.00% Add +3000.0% 124 $40K
MAI Capital Management 0.00% Add +2550.0% 106 $34K
Larson Financial Group LLC 0.00% Add +8.9% 98 $32K
Osaic Holdings, Inc. 0.00% Add +13.3% 94 $30K
Smartleaf Asset Management LLC 0.00% Add +33.8% 99 $27K
Pinnacle Wealth Planning Services, Inc. 0.00% New 81 $26K
Allworth Financial LP 0.00% Add +167.9% 75 $24K
Rothschild Investment LLC 0.00% Add +38.0% 69 $22K
SBI Securities Co., Ltd. 0.00% Reduce -9.5% 67 $22K
J.Safra Asset Management Corp 0.00% Add +200.0% 54 $17K
Accent Capital Management, LLC 0.01% No change 50 $16K
EverSource Wealth Advisors, LLC 0.00% Add +100.0% 50 $16K
First Horizon Corp. 0.00% New 48 $15K
E Fund Management (Hong Kong) Co., Ltd. 0.01% New 46 $15K
Federated Hermes, Inc. 0.00% No change 44 $14K
Arax Advisory Partners 0.00% Reduce -40.6% 38 $12K
Optiver Holding B.V. 0.00% Reduce -38.3% 37 $12K
Aster Capital Management (DIFC) Ltd 0.00% New 260 $10K
Signaturefd, LLC 0.00% New 30 $10K
Jones Financial Companies LLLP 0.00% New 31 $9K
Rakuten Securities, Inc. 0.00% New 25 $8K
Covestor Ltd 0.01% Add +1100.0% 24 $8K
Basecamp Wealth Advisors LLC 0.00% Add +50.0% 24 $8K
Ascentis Independent Advisors 0.00% New 24 $8K
AdvisorNet Financial, Inc 0.00% New 20 $6K
Meeder Asset Management Inc. 0.00% New 16 $5K
Parkside Financial Bank & Trust 0.00% No change 14 $5K
Bare Financial Services, Inc 0.00% Add +11.1% 10 $3K
Steward Partners Investment Advisory, LLC 0.00% New 10 $3K
Keating Financial Advisory Services, Inc. 0.00% Add +700.0% 8 $3K
Fortitude Family Office, LLC 0.00% New 7 $2K
MassMutual Private Wealth & Trust, FSB 0.00% New 7 $2K
Root Financial Partners, LLC 0.00% New 7 $2K
IFP Advisors, Inc 0.00% No change 6 $2K
Wealth Preservation Advisors, LLC 0.00% New 5 $2K
Twin Peaks Wealth Advisors, LLC 0.00% New 5 $2K
Bell Investment Advisors, Inc 0.00% No change 5 $2K
Essential Partners LLC 0.00% No change 4 $1K
Physician Wealth Advisors, Inc. 0.00% New 4 $1K
SJS Investment Consulting Inc. 0.00% Add +300.0% 4 $1K
Versant Capital Management, Inc 0.00% New 2 $644
Zions Bancorporation, National Association 0.00% New 2 $644
National Bank of Canada 0.00% New 2 $641
Quadrant Capital Group LLC 0.00% New 1 $323
Bogart Wealth, LLC 0.00% New 1 $322
Hughes Financial Services, LLC 0.00% New 1 $322

"% of holder's portfolio" is PRAX's weight in each manager's 13F, not the share of Praxis Precision Medicines I the manager owns.